Publications by authors named "Christopher R Gignoux"

66Publications

A common variant in PNPLA3 is associated with age at diagnosis of NAFLD in patients from a multi-ethnic biobank.

J Hepatol 2020 Jun 5;72(6):1070-1081. Epub 2020 Mar 5.

The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.jhep.2020.01.029DOI Listing
June 2020

Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 Sep 4;10(1):4082. Epub 2019 Sep 4.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-12158-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726619PMC
September 2019

Genetic analyses of diverse populations improves discovery for complex traits.

Nature 2019 06 19;570(7762):514-518. Epub 2019 Jun 19.

Division of Public Health Science, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41586-019-1310-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785182PMC
June 2019

The Future of Genomic Studies Must Be Globally Representative: Perspectives from PAGE.

Annu Rev Genomics Hum Genet 2019 08 12;20:181-200. Epub 2019 Apr 12.

Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA; email:

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http://dx.doi.org/10.1146/annurev-genom-091416-035517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012212PMC
August 2019

Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

Nat Commun 2019 02 20;10(1):880. Epub 2019 Feb 20.

Department of Medicine, University of Colorado Denver, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1038/s41467-019-08469-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382865PMC
February 2019

Rapid evolution of a skin-lightening allele in southern African KhoeSan.

Proc Natl Acad Sci U S A 2018 12 10;115(52):13324-13329. Epub 2018 Dec 10.

Department of Ecology and Evolution, State University of New York at Stony Brook, Stony Brook, NY 11794;

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http://dx.doi.org/10.1073/pnas.1801948115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310813PMC
December 2018

An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos.

J Allergy Clin Immunol 2019 03 7;143(3):957-969. Epub 2018 Sep 7.

Program in Pharmaceutical Sciences and Pharmacogenomics, University of California, San Francisco, San Francisco, Calif; Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, Calif; Department of Medicine, University of California, San Francisco, San Francisco, Calif.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183127
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http://dx.doi.org/10.1016/j.jaci.2016.08.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927816PMC
March 2019

Genetic diversity in populations across Latin America: implications for population and medical genetic studies.

Curr Opin Genet Dev 2018 12 17;53:98-104. Epub 2018 Aug 17.

Colorado Center for Personalized Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA; Department of Biostatistics and Informatics, School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2018.07.006DOI Listing
December 2018

An ancestry-based approach for detecting interactions.

Genet Epidemiol 2018 02 8;42(1):49-63. Epub 2017 Nov 8.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/gepi.22087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065511PMC
February 2018

Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations.

Am J Hum Genet 2017 Apr 30;100(4):635-649. Epub 2017 Mar 30.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Center of Statistical Genetics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384097PMC
April 2017

Making Precision Medicine Socially Precise. Take a Deep Breath.

Am J Respir Crit Care Med 2016 Feb;193(4):348-50

1 Department of Medicine University of California, San Francisco San Francisco, California.

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http://dx.doi.org/10.1164/rccm.201510-2045EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803087PMC
February 2016

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

PLoS Genet 2015 Aug 20;11(8):e1005439. Epub 2015 Aug 20.

Departments of Structural Biology and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546388PMC
August 2015

Using multi-way admixture mapping to elucidate TB susceptibility in the South African Coloured population.

BMC Genomics 2014 Nov 25;15:1021. Epub 2014 Nov 25.

Molecular Biology and Human Genetics, MRC Centre for TB Research and the DST/NRF Centre of Excellence for Biomedical TB Research, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.

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http://dx.doi.org/10.1186/1471-2164-15-1021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256931PMC
November 2014

Dissecting childhood asthma with nasal transcriptomics distinguishes subphenotypes of disease.

J Allergy Clin Immunol 2014 Mar 2;133(3):670-8.e12. Epub 2014 Feb 2.

Integrated Center for Genes, Environment, and Health, National Jewish Health, Denver, Colo; Department of Pediatrics, National Jewish Health, Denver, Colo; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado-Denver, Denver, Colo. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043390PMC
March 2014

Gene flow from North Africa contributes to differential human genetic diversity in southern Europe.

Proc Natl Acad Sci U S A 2013 Jul 3;110(29):11791-6. Epub 2013 Jun 3.

Institut de Biologia Evolutiva, Consejo Superior de Investigaciones Científicas-Universitat Pompeu Fabra, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1073/pnas.1306223110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718088PMC
July 2013

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

Nat Genet 2011 Jul 31;43(9):887-92. Epub 2011 Jul 31.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445408PMC
http://dx.doi.org/10.1038/ng.888DOI Listing
July 2011

Rapid, global demographic expansions after the origins of agriculture.

Proc Natl Acad Sci U S A 2011 Apr 28;108(15):6044-9. Epub 2011 Mar 28.

University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1073/pnas.0914274108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076817PMC
April 2011

Characterizing the time dependency of human mitochondrial DNA mutation rate estimates.

Mol Biol Evol 2009 Jan 4;26(1):217-30. Epub 2008 Nov 4.

Department of Anthropology, Stanford University, USA.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msn244DOI Listing
January 2009