Publications by authors named "Christopher P Denton"

292Publications

Efficacy and safety of nintedanib in patients with systemic sclerosis-associated interstitial lung disease treated with mycophenolate: a subgroup analysis of the SENSCIS trial.

Lancet Respir Med 2021 01;9(1):96-106

National Heart and Lung Institute, Imperial College London, London, UK; National Institute for Health Research Clinical Research Facility, Royal Brompton Hospital, London, UK; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

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January 2021

Rituximab for the treatment of systemic sclerosis-interstitial lung disease.

Rheumatology (Oxford) 2020 Nov 27. Epub 2020 Nov 27.

Scleroderma Program, University of Michigan, Ann Arbor, MI, USA.

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November 2020

STRATUS, a Phase II Study of Abituzumab in Patients with Systemic Sclerosis-associated Interstitial Lung Disease.

J Rheumatol 2020 Oct 1. Epub 2020 Oct 1.

From the University of Michigan, Ann Arbor, MI, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Royal Brompton Hospital, London, UK; Scleroderma Research Consultants, LLC, Aiken, SC, USA; EMD Serono Inc., Billerica, MA, USA; University College London Medical School, Royal Free Hospital, London, UK. The STRATUS study was sponsored by Merck KGaA (for all study sites residing in countries outside of the USA) or EMD Serono Research and Development Institute, Inc., Billerica, MA, USA* (for study sites residing within the USA). Medical writing assistance was provided by Dan Booth (Bioscript Science, Macclesfield, UK) and funded by Merck KGaA. The STRATUS study was funded by Merck KGaA, Darmstadt, Germany and EMD Serono Research Institute Inc. (a business of Merck KGaA, Darmstadt, Germany). Merck KGaA authors were involved in the study design, collection, analysis and interpretation of the data, and in the writing of and decision to submit the manuscript. Address correspondence to Dr Dinesh Khanna, Division of Rheumatology, Department of Internal Medicine, University of Michigan Scleroderma Program, Ann Arbor, MI 48109, USA. Email:

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October 2020

High proton pump inhibitor exposure increases risk of calcinosis in systemic sclerosis.

Rheumatology (Oxford) 2020 Aug 23. Epub 2020 Aug 23.

Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, Royal Free Campus, London, UK.

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August 2020

News and failures from recent treatment trials in systemic sclerosis.

Eur J Rheumatol 2020 Oct 20;7(Suppl 3):S242-S248. Epub 2020 Jul 20.

Division of Medicine, Centre for Rheumatology, University College London, London, UK.

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October 2020

Analysis of Anti-RNA Polymerase III Antibody-positive Systemic Sclerosis and Altered GPATCH2L and CTNND2 Expression in Scleroderma Renal Crisis.

J Rheumatol 2020 11 15;47(11):1668-1677. Epub 2020 Mar 15.

S.G. Guerra, PhD, H. Chinque, BSc, V. Acquaah, BSc, M. Ponticos, V.H. Ong, PhD, FRCP, K. Khan, BSc, S.I. Nihtyanova, MD, C. Fonseca, MD, C.P. Denton, PhD, FRCP, Professor of Experimental Rheumatology, UCL Centre for Rheumatology and Connective Tissue Diseases, London, UK;

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November 2020

Scleroderma mimics - Clinical features and management.

Best Pract Res Clin Rheumatol 2020 02 5;34(1):101489. Epub 2020 Mar 5.

Centre for Rheumatology, Royal Free Campus, University College London, Rowland Hill Street, London NW3 2PF, UK. Electronic address:

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February 2020

Challenges in evidence-based therapy for systemic sclerosis associated interstitial lung disease.

Lancet Respir Med 2020 03 27;8(3):226-227. Epub 2020 Feb 27.

Division of Medicine, Royal Free Campus, University College London, London NW3 2PF, UK.

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March 2020