Publications by authors named "Christopher P Crum"

100Publications

Synovial Sarcoma of the Female Genital Tract: A Protean Mimic of Müllerian Neoplasia.

Am J Surg Pathol 2020 Nov;44(11):1487-1495

Department of Pathology, Division of Women's and Perinatal Pathology.

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http://dx.doi.org/10.1097/PAS.0000000000001538DOI Listing
November 2020

Molecular characterization of diffuse malignant peritoneal mesothelioma.

Mod Pathol 2020 Jun 5. Epub 2020 Jun 5.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41379-020-0588-yDOI Listing
June 2020

MicroRNA-200 family governs ovarian inclusion cyst formation and mode of ovarian cancer spread.

Oncogene 2020 May 25;39(20):4045-4060. Epub 2020 Mar 25.

Department of Obstetrics/Gynecology and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41388-020-1264-xDOI Listing
May 2020

Evidence for a Novel Endometrioid Carcinogenic Sequence in the Fallopian Tube With Unique Beta-Catenin Expression.

Int J Gynecol Pathol 2020 Mar;39(2):163-169

Department of Obstetrics and Gynecology, University Medical Center Gronigen, University of Gronigen, Groningen, The Netherlands (J.B., M.J.M.) Department of Pathology, Duke University Medical Center, Durham, North Carolina (K.C.S.) Jackson Laboratory for Genomic Medicine, Farmington, Connecticut (G.N.) Department of Pathology, Brigham and Women's Hospital (C.B.S., D.L.K., M.R.N., C.P.C.) Department of Pathology, Beth Israel Deaconess Hospital (J.H.), Boston, Massachusetts Institute of Molecular Medicine, University of Texas Health Sciences Center, Houston, Texas (W.X.).

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http://dx.doi.org/10.1097/PGP.0000000000000590DOI Listing
March 2020

Guidelines to Aid in the Distinction of Endometrial and Endocervical Carcinomas, and the Distinction of Independent Primary Carcinomas of the Endometrium and Adnexa From Metastatic Spread Between These and Other Sites.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S75-S92

Department of Histopathology, King Edward Memorial Hospital and School for Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia (C.J.R.S.) Department of Pathology, Brigham and Women's Hospital (C.P.C.) Department of Pathology, Massachusetts General Hospital and Harvard Medical School (E.O.), Boston, Massachusetts Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK (W.G.M.) Department of Pathology, Memorial-Sloan Kettering Cancer Center, New York, New York (K.J.P.) Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California (J.K.R.) Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.M.) Department of Pathology, Yale University School of Medicine, New Haven, Connecticut (V.P.) Pathological Oncology Group and Pathology Department, Hospital Arnau de Vilanova, Lleida, Spain (X.M.-G.) Departments of Pathology and Gynecology and Obstetrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland (B.M.R.).

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http://dx.doi.org/10.1097/PGP.0000000000000553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296834PMC
January 2019

High-grade Endometrial Carcinomas: Morphologic and Immunohistochemical Features, Diagnostic Challenges and Recommendations.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S40-S63

Department of Pathology, Memorial Sloan Kettering Cancer Center (R.M., R.A.S.) New York University Medical Center and School of Medicine, Tisch Hospital (K.M.), New York Department of Pathology, University Hospital, Stony Brook School of Medicine, Stony Brook (C.T.), New York Department of Pathology, Oslo University Hospital, Norwegian Radium Hospital; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway (B.D.) Department of Pathology, University of California San Diego, San Diego (O.F.) Department of Pathology, Cedars-Sinai Medical Center, Los Angeles (J.K.L.R.), California Department of Pathology, Karolinska Institutet, Stockholm, Sweden (J.A.C.) Department of Pathology, Brigham and Women's Hospital, Harvard Medical School (C.P.C.) Department of Pathology, Massachussetts General Hospital, Harvard Medical School (E.O.), Boston, Massachussetts Department of Pathology, University of British Columbia, Vancouver (C.B.G., J.A.I.) Department of Laboratory Medicine, Pathology and Medical Genetics, Royal Jubilee Hospital, Victoria (J.A.I.), BC, Canada Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas (A.M.) Department of Pathology, Hospital University Arnau de Vilanova; and Department of Pathology, Hospital University de Bellvitge, IRBLLEIDA, IDIBELL, University of Lleida, CIBERONC, Barcelona, Spain (X.M.-G.) Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK (W.G.M.) Department of Pathology and Obstetrics and Gynecology, Yale School of Medicine and Yale School of Publich Health, New Haven, Connecticut (V.P.) Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland (P.N.S.) Department of Pathology, KEMH and School for Women's and Infants' Health, University of Western Australia, Perth, WA, Australia (C.J.R.S.).

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http://dx.doi.org/10.1097/PGP.0000000000000491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296248PMC
January 2019

The fallopian tube, "precursor escape" and narrowing the knowledge gap to the origins of high-grade serous carcinoma.

Gynecol Oncol 2019 02 30;152(2):426-433. Epub 2018 Nov 30.

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, MA 02115, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258183145
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http://dx.doi.org/10.1016/j.ygyno.2018.11.033DOI Listing
February 2019

Back to the Future? The Fallopian Tube, Precursor Escape and a Dualistic Model of High-Grade Serous Carcinogenesis.

Cancers (Basel) 2018 Nov 28;10(12). Epub 2018 Nov 28.

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/cancers10120468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316244PMC
November 2018

Frontiers in the Pathology and Pathogenesis of Ovarian Cancer: Cancer Precursors and "Precursor Escape".

Hematol Oncol Clin North Am 2018 12;32(6):915-928

Department of Pathology, Harvard Medical School, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2018.07.013DOI Listing
December 2018

HPV 6-associated HSIL/Squamous Carcinoma in the Anogenital Tract.

Int J Gynecol Pathol 2019 Sep;38(5):493-497

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts (M.Z.L., Y.P.H., M.R.N., C.P.C.) Department of Pathology, Division of Cytopathology, University of Washington Health Sciences Center, Seattle, Washington (E.C.H.) Department of Pathology, Stanford University Medical Center, Palo Alto, California (B.E.H.).

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http://Insights.ovid.com/crossref?an=00004347-900000000-9915
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http://dx.doi.org/10.1097/PGP.0000000000000556DOI Listing
September 2019

An Efficient Method for Cloning Gastrointestinal Stem Cells From Patients via Endoscopic Biopsies.

Gastroenterology 2019 01 6;156(1):20-23. Epub 2018 Oct 6.

Institute of Molecular Medicine, McGovern Medical School of University of Texas Health Science Center, Houston, Texas; Department of Biochemistry and Molecular Biology, McGovern Medical School of University of Texas Health Science Center, Houston, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183508
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http://dx.doi.org/10.1053/j.gastro.2018.08.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309951PMC
January 2019

Targeted Genomic Profiling of Female Adnexal Tumors of Probable Wolffian Origin (FATWO).

Int J Gynecol Pathol 2019 Nov;38(6):543-551

Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (J.M.) Department of Pathology (F.D., L.M.S., E.G., N.L.) Department of Pathology, Division of Women's and Perinatal Pathology (J.M., C.P.C., M.R.N., B.E.H.), Brigham and Women's Hospital Dana-Farber Cancer Institute (E.G., L.M.), Boston, Massachusetts Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK (W.G.M.) Department of Pathology, Stanford University School of Medicine, Stanford, California (B.E.H.).

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http://Insights.ovid.com/crossref?an=00004347-900000000-9915
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http://dx.doi.org/10.1097/PGP.0000000000000545DOI Listing
November 2019

Surgical prevention strategies in ovarian cancer.

Gynecol Oncol 2018 10 4;151(1):166-175. Epub 2018 Aug 4.

Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, United States of America; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2018.08.005DOI Listing
October 2018

Evidence for lineage continuity between early serous proliferations (ESPs) in the Fallopian tube and disseminated high-grade serous carcinomas.

J Pathol 2018 11 27;246(3):344-351. Epub 2018 Sep 27.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/path.5145DOI Listing
November 2018

Evidence of a Monoclonal Origin for Bilateral Serous Tubal Intraepithelial Neoplasia.

Int J Gynecol Pathol 2019 Sep;38(5):443-448

Department of Pathology, Maine Medical Center, Portland, Maine (E.E.M.) Department of Pathology, Duke University Medical Center, Durham, North Carolina (K.C.S.) PlexSeq Diagnostics, Cleveland, Ohio (A.M., F.C.) Department of Pathology, Division of Women's and Perinatal Pathology, Brigham; and Women's Hospital, Boston, Massachusetts (T.R.S., C.P.C.) Department of Pathology, Stanford University Medical Center, Stanford, California (B.E.H.).

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http://dx.doi.org/10.1097/PGP.0000000000000534DOI Listing
September 2019

Classic Vulvar Intraepithelial Neoplasia With Superimposed Lichen Simplex Chronicus: A Unique Variant Mimicking Differentiated Vulvar Intraepithelial Neoplasia.

Int J Gynecol Pathol 2019 Mar;38(2):175-182

Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts (J.C.W., C.P.C., M.R.N.) Stanford University Hospital, Palo Alto, California (E.Y.) Laboratory of Experimental Pathology, GIGA-Cancer, University of Liege, Liege, Belgium (M.H.) Infections and Cancer Biology Group, International Agency for Research on Cancer, Lyon, France (T.G., M.T.).

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http://dx.doi.org/10.1097/PGP.0000000000000509DOI Listing
March 2019

Assessment of a Chemotherapy Response Score (CRS) System for Tubo-Ovarian High-Grade Serous Carcinoma (HGSC).

Int J Gynecol Pathol 2019 May;38(3):230-240

Department of Pathology, Women's and Perinatal Pathology Division (H.M.D., K.C.S., E.E.M., W.R.W., M.S.H., B.J.Q., K.R.L., C.P.C., G.L.M., M.R.N., B.E.H.) Division of Gynecologic Oncology and Reproductive Biology (M.G.M., J.F.L., C.F., N.H., R.S.B.), Brigham and Women's Hospital Department of Pathology, Beth Israel Deaconess Medical Center (M.G., J.L.H., D.I.L.) Medical Gynecologic Oncology Program, Dana-Farber Cancer Institute (E.S., P.A.K., U.A.M.), Harvard Medical School, Boston, Massachusetts Department of Pathology, Duke University Medical Center, Durham, North Carolina (K.C.S.) Department of Gynecology and Obstetrics, Odense University Hospital, University of Southern Denmark, Odense, Denmark (K.M.J.) Department of Pathology, Stanford University, Stanford, California (B.E.H.).

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http://dx.doi.org/10.1097/PGP.0000000000000513DOI Listing
May 2019

SMARCA4-deficient undifferentiated uterine sarcoma (malignant rhabdoid tumor of the uterus): a clinicopathologic entity distinct from undifferentiated carcinoma.

Mod Pathol 2018 09 26;31(9):1442-1456. Epub 2018 Apr 26.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA.

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http://www.nature.com/articles/s41379-018-0049-z
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http://dx.doi.org/10.1038/s41379-018-0049-zDOI Listing
September 2018

Origin of clear cell carcinoma: nature or nurture?

J Pathol 2018 Feb 2;244(2):131-134. Epub 2018 Jan 2.

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/path.5009DOI Listing
February 2018

Comprehensive Human Papillomavirus Genotyping in Cervical Squamous Cell Carcinomas and Its Relevance to Cervical Cancer Prevention in Malawian Women.

J Glob Oncol 2017 Jun 10;3(3):227-234. Epub 2016 Aug 10.

, , and , Brigham and Women's Hospital, Boston, MA; and , University of Liege, Liege, Belgium; , , and , Malawi College of Medicine, Blantyre, Malawi; and and , International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1200/JGO.2015.001909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493214PMC
June 2017

Epidermodysplasia Verruciformis-like HPV Infection of the Vulva in Immunosuppressed Women.

Int J Gynecol Pathol 2018 May;37(3):233-238

Departments of Obstetrics and Gynecology and Pathology, Bangkok Hospital, Bangkok, Thailand (N.P.) Department of Obstetrics and Gynecology, Division of Gynecologic Oncology (S.F.) Division of Dermatopathology (S.R.G., A.C.L.) Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, MA (C.P.C.) Laboratory of Experimental Pathology, GIGA-Cancer, Liege, Belgium (M.H.).

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http://dx.doi.org/10.1097/PGP.0000000000000417DOI Listing
May 2018

Frequency of "incidental" serous tubal intraepithelial carcinoma (STIC) in women without a history of or genetic risk factor for high-grade serous carcinoma: A six-year study.

Gynecol Oncol 2017 07 4;146(1):69-73. Epub 2017 May 4.

Division of Women's & Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258173079
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http://dx.doi.org/10.1016/j.ygyno.2017.04.015DOI Listing
July 2017

Deciphering the Multifactorial Susceptibility of Mucosal Junction Cells to HPV Infection and Related Carcinogenesis.

Viruses 2017 04 20;9(4). Epub 2017 Apr 20.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/v9040085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408691PMC
April 2017

Serous tubal intraepithelial neoplasia: the concept and its application.

Mod Pathol 2017 05 20;30(5):710-721. Epub 2017 Jan 20.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA USA.

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http://dx.doi.org/10.1038/modpathol.2016.238DOI Listing
May 2017

Universal Screening for Mismatch-Repair Deficiency in Endometrial Cancers to Identify Patients With Lynch Syndrome and Lynch-like Syndrome.

Int J Gynecol Pathol 2017 Mar;36(2):115-127

Departments of Pathology (J.C.W., J.L.H., C.P.C, L.M.S., B.E.H.) Gynecologic Oncology (M.C.M., C.M.F., R.S.B., N.S.H.), Brigham And Women's Hospital Department of Medical Oncology (S.S., M.B.Y., A.C.), Dana-Farber Cancer Institute, Boston, MA Department of Pathology (E.J.Y.), Stanford University Medical Center, Palo Alto, CA.

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http://dx.doi.org/10.1097/PGP.0000000000000312DOI Listing
March 2017

p16ink4 and cytokeratin 7 immunostaining in predicting HSIL outcome for low-grade squamous intraepithelial lesions: a case series, literature review and commentary.

Mod Pathol 2016 12 12;29(12):1501-1510. Epub 2016 Aug 12.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.141DOI Listing
December 2016

Vestibular Mast Cell Density in Vulvodynia: A Case-Controlled Study.

J Low Genit Tract Dis 2016 Jul;20(3):275-9

1Department of Obstetrics and Gynaecology, Shrewsbury and Telford Hospitals NHS Trust, Shrewsbury, UK.; 2Center for Vulvar Diseases, Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, MI, USA; 3Department of Pathology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA; and 4Department of Family Medicine, University of Michigan Health System, Ann Arbor, MI, USA.

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http://pdfs.journals.lww.com/jlgtd/2016/07000/Vestibular_Mas
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/LGT.0000000000000221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920700PMC
July 2016

Preventing Ovarian Cancer.

J Clin Oncol 2016 Jan 16;34(2):198-9. Epub 2015 Nov 16.

Brigham and Women's Hospital, Boston, MA

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http://dx.doi.org/10.1200/JCO.2015.62.9519DOI Listing
January 2016

Stathmin 1 and p16(INK4A) are sensitive adjunct biomarkers for serous tubal intraepithelial carcinoma.

Gynecol Oncol 2015 Oct 20;139(1):104-11. Epub 2015 Jul 20.

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2015.07.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586950PMC
October 2015

Cloning and variation of ground state intestinal stem cells.

Nature 2015 Jun 3;522(7555):173-8. Epub 2015 Jun 3.

1] The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06032, USA [2] Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06032, USA [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02118, USA [4] Department of Medicine, National University of Singapore, 119228 Singapore [5] Multiclonal Therapeutics, Inc., Farmington, Connecticut 06032, USA.

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http://dx.doi.org/10.1038/nature14484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853906PMC
June 2015

Cervical cancer: squamocolumnar junction ablation--tying up loose ends?

Nat Rev Clin Oncol 2015 Jul 2;12(7):378-80. Epub 2015 Jun 2.

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/nrclinonc.2015.104DOI Listing
July 2015

Ovarian cancer survival by tumor dominance, a surrogate for site of origin.

Cancer Causes Control 2015 Apr 13;26(4):601-8. Epub 2015 Mar 13.

Women's College Research Institute, Women's College Hospital, 790 Bay Street, 7th Floor, Toronto, ON, M5G 1N8, Canada.

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http://dx.doi.org/10.1007/s10552-015-0547-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561551PMC
April 2015

Salpingectomy as a potential ovarian cancer risk-reducing procedure.

J Natl Cancer Inst 2015 Feb 27;107(2). Epub 2015 Jan 27.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (EMP, MSR, SST); Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA (CPC); Department of Epidemiology, Harvard School of Public Health, Boston, MA (SST).

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http://dx.doi.org/10.1093/jnci/dju490DOI Listing
February 2015

Evidence for a dualistic model of high-grade serous carcinoma: BRCA mutation status, histology, and tubal intraepithelial carcinoma.

Am J Surg Pathol 2015 Mar;39(3):287-93

*Department of Pathology, Division of Women's and Perinatal Pathology §Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Brigham and Women's Hospital ‡Dana Farber Cancer Institute, Boston MA †Department of Pathology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

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http://dx.doi.org/10.1097/PAS.0000000000000369DOI Listing
March 2015

The utility of immunohistochemistry in the differential diagnosis of gynecologic disorders.

Arch Pathol Lab Med 2015 Jan;139(1):39-54

From the Department of Laboratory Medicine, Geisinger Health System, Wilkes-Barre, Pennsylvania (Dr Kaspar);

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http://dx.doi.org/10.5858/arpa.2014-0057-RADOI Listing
January 2015

p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.

Nature 2015 Jan 12;517(7536):616-20. Epub 2014 Nov 12.

1] Genome Institute of Singapore, A-STAR, 138672 Singapore [2] The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut 06032, USA [3] Department of Medicine, National University Health System, 119228 Singapore.

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http://www.nature.com/articles/nature13903
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http://dx.doi.org/10.1038/nature13903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095488PMC
January 2015

Response to "Two major pathways of recurrent high-grade squamous intraepithelial lesions of the cervix".

Int J Cancer 2015 Nov 8;137(10):2522-3. Epub 2014 Aug 8.

Division of Women's and Perinatal Pathology, Department of pathology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1002/ijc.29116DOI Listing
November 2015

Unique recurrence patterns of cervical intraepithelial neoplasia after excision of the squamocolumnar junction.

Int J Cancer 2015 Mar 3;136(5):1043-52. Epub 2014 Jul 3.

Department of Pathology, Laboratory of Experimental Pathology, GIGA-Cancer, University of Liege, Liege, Belgium.

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http://dx.doi.org/10.1002/ijc.28978DOI Listing
March 2015

Landscape of genomic alterations in cervical carcinomas.

Nature 2014 Feb 25;506(7488):371-5. Epub 2013 Dec 25.

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] The Eli and Edythe L. Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [4].

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http://dx.doi.org/10.1038/nature12881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161954PMC
February 2014

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models.

Cancer Cell 2013 Dec;24(6):751-65

Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917315PMC
December 2013

Gene expression signature of normal cell-of-origin predicts ovarian tumor outcomes.

PLoS One 2013 26;8(11):e80314. Epub 2013 Nov 26.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America ; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America ; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080314PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841174PMC
October 2014

The multidrug-resistance transporter ABCB5 is expressed in human placenta.

Int J Gynecol Pathol 2014 Jan;33(1):45-51

Departments of Pathology (E.R.V., C.L., Q.Z., C.P.C., G.F.M Dermatology (S.D.G., M.H.F.) Division of Genetics (N.Y.F.), Brigham and Women's Hospital Harvard Medical School (E.R.V., C.L., Q.Z., S.D.G., M.H.F., N.Y.F., C.P.C., G.F.M.) Transplantation Research Center (M.H.F., N.Y.F.), Children's Hospital, Boston Converge Diagnostic Services (D.W.K.), Peabody Department of Medicine (N.Y.F.), VA Boston Healthcare System, Jamaica Plain, Massachusetts.

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http://dx.doi.org/10.1097/PGP.0b013e31829c677fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909935PMC
January 2014

Cervical squamocolumnar junction-specific markers define distinct, clinically relevant subsets of low-grade squamous intraepithelial lesions.

Am J Surg Pathol 2013 Sep;37(9):1311-8

*Department of Pathology, Division of Women's and Perinatal Pathology §Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA ‡Department of Pathology, Cedar Sinai Medical Center, Los Angeles, CA †Department of Pathology, GIGA-Cancer, University of Liege, Liege, Belgium ∥Genome Institute of Singapore, ASTAR The Jackson Laboratory for Genomic Medicine, CT ¶The Jackson Laboratory for Genomic Medicine, The University of Connecticut School of Medicine, CT.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905241PMC
September 2013

Through the glass darkly: intraepithelial neoplasia, top-down differentiation, and the road to ovarian cancer.

J Pathol 2013 Dec;231(4):402-12

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1002/path.4263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947463PMC
December 2013

Phosphorylated S6 as an immunohistochemical biomarker of vulvar intraepithelial neoplasia.

Mod Pathol 2013 Nov 14;26(11):1498-507. Epub 2013 Jun 14.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2013.85DOI Listing
November 2013

Relationship of margin status and radiation dose to recurrence in post-operative vulvar carcinoma.

Gynecol Oncol 2013 Sep 5;130(3):545-9. Epub 2013 Jun 5.

Department of Radiation Oncology, Brigham and Women's Hospita and Dana-Farber Cancer Institutel, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ygyno.2013.05.036DOI Listing
September 2013

Differential expression of p-ERM, a marker of cell polarity, in benign and neoplastic oviductal epithelium.

Int J Gynecol Pathol 2013 Jul;32(4):345-52

Department of Cell Biology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1097/PGP.0b013e31826feee2DOI Listing
July 2013

Laboratory management of cervical intraepithelial neoplasia: proposing a new paradigm.

Adv Anat Pathol 2013 Mar;20(2):86-94

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/PAP.0b013e3182862aabDOI Listing
March 2013

Giant condyloma of the cervix: an uncommon entity associated with low-risk human papilloma virus infection.

Am J Surg Pathol 2013 Feb;37(2):300-4

Department of Pathology, Women's and Perinatal Pathology Division, Brigham and Women's Hospital-Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/PAS.0b013e31826d261eDOI Listing
February 2013

Low-grade and high-grade serous Mullerian carcinoma: review and analysis of publicly available gene expression profiles.

Gynecol Oncol 2013 Mar 16;128(3):488-92. Epub 2012 Dec 16.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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March 2013

Stathmin-1 expression as a complement to p16 helps identify high-grade cervical intraepithelial neoplasia with increased specificity.

Am J Surg Pathol 2013 Jan;37(1):89-97

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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January 2013

Peritoneal dissemination complicating morcellation of uterine mesenchymal neoplasms.

PLoS One 2012 26;7(11):e50058. Epub 2012 Nov 26.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham & Women's Hospital/Harvard Medical School, Boston, Massachussetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506532PMC
May 2013

Our wages of CIN.

Obstet Gynecol 2012 Dec;120(6):1261-2

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http://dx.doi.org/10.1097/aog.0b013e31827736b7DOI Listing
December 2012

A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia.

J Pathol 2013 Feb;229(3):460-8

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/path.4110DOI Listing
February 2013

Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.

PLoS Genet 2012 16;8(8):e1002906. Epub 2012 Aug 16.

Vincent Center for Reproductive Biology, Department of Obstetrics, Gynecology, and Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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https://dx.doi.org/10.1371/journal.pgen.1002906
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http://dx.doi.org/10.1371/journal.pgen.1002906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3420942PMC
December 2012

Digital quantification of precursor frequency in the fallopian tube and its significance.

Mod Pathol 2012 Dec 6;25(12):1654-61. Epub 2012 Jul 6.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://www.nature.com/articles/modpathol2012100
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December 2012

A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer.

Proc Natl Acad Sci U S A 2012 Jun 11;109(26):10516-21. Epub 2012 Jun 11.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1202684109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387104PMC
June 2012

BRCA, the oviduct, and the space and time continuum of pelvic serous carcinogenesis.

Int J Gynecol Cancer 2012 May;22 Suppl 1:S29-34

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0b013e31824d7269DOI Listing
May 2012

Cellular origin of Barrett's esophagus: controversy and therapeutic implications.

Gastroenterology 2012 Jun 23;142(7):1424-30. Epub 2012 Apr 23.

Institute of Medical Biology, A*STAR, Singapore.

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http://dx.doi.org/10.1053/j.gastro.2012.04.028DOI Listing
June 2012

Screening of symptomatic women for ovarian cancer.

Lancet Oncol 2012 Apr 30;13(4):e137; author reply e139-40. Epub 2012 Mar 30.

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http://dx.doi.org/10.1016/S1470-2045(12)70104-3DOI Listing
April 2012

The oviduct and ovarian cancer: causality, clinical implications, and "targeted prevention".

Clin Obstet Gynecol 2012 Mar;55(1):24-35

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/GRF.0b013e31824b1725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319355PMC
March 2012

Fallopian tube correlates of ovarian serous borderline tumors.

Am J Surg Pathol 2011 Dec;35(12):1759-65

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/PAS.0b013e318233b0f7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219906PMC
December 2011

PAX2-null secretory cell outgrowths in the oviduct and their relationship to pelvic serous cancer.

Mod Pathol 2012 Mar 11;25(3):449-55. Epub 2011 Nov 11.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2011.175DOI Listing
March 2012

Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming.

Proc Natl Acad Sci U S A 2011 Feb 18;108(5):2130-5. Epub 2011 Jan 18.

Infectious Diseases Division, Department of Medicine, The Channing Laboratory, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1009933108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033314PMC
February 2011

STICS, SCOUTs and p53 signatures; a new language for pelvic serous carcinogenesis.

Front Biosci (Elite Ed) 2011 Jan 1;3:625-34. Epub 2011 Jan 1.

Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.2741/e275DOI Listing
January 2011

High-grade and low-grade pelvic serous neoplasms demonstrate differential p53 immunoreactivity in peritoneal washings.

Acta Cytol 2011 26;55(1):79-84. Epub 2010 Nov 26.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1159/000320862DOI Listing
April 2011

MOLECULAR MARKERS OF EARLY CERVICAL NEOPLASIA.

Diagn Histopathol (Oxf) 2010 Oct;16(10):445-454

Department of Pathology at the Federal University of Paraná, Curitiba, PR, Brazil. Conflicts of interest: Alvaro Pinto received test reagents from Becton, Dickinson and Company to perform comparisons of ProEx C and other biomarkers.

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http://dx.doi.org/10.1016/j.mpdhp.2010.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975942PMC
October 2010

CA125 immune complexes in ovarian cancer patients with low CA125 concentrations.

Clin Chem 2010 Dec 13;56(12):1889-92. Epub 2010 Oct 13.

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1373/clinchem.2010.153122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079311PMC
December 2010

Bringing the p53 signature into focus.

Cancer 2010 Nov;116(22):5119-21

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http://dx.doi.org/10.1002/cncr.25450DOI Listing
November 2010

Clinical outcome in diagnostically ambiguous foci of 'gland crowding' in the endometrium.

Mod Pathol 2010 Nov 30;23(11):1486-91. Epub 2010 Jul 30.

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2010.140DOI Listing
November 2010

Secretory cell outgrowth, PAX2 and serous carcinogenesis in the Fallopian tube.

J Pathol 2010 Sep;222(1):110-6

Division of Women's and Perinatal Pathology, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/path.2739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914810PMC
September 2010