Publications by authors named "Christopher Overall"

100Publications

The HUPO High-Stringency Inventory of Humanity's Shared Human Proteome Revealed.

J Proteome Res 2020 Nov 19;19(11):4211-4214. Epub 2020 Oct 19.

Centre for Blood Research, Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, Faculty of Dentistry, The University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.

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http://dx.doi.org/10.1021/acs.jproteome.0c00794DOI Listing
November 2020

Experimental autoimmune encephalomyelitis is associated with changes of the microbiota composition in the gastrointestinal tract.

Sci Rep 2020 09 16;10(1):15183. Epub 2020 Sep 16.

Center for Brain Immunology and Glia, University of Virginia, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1038/s41598-020-72197-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494894PMC
September 2020

Cost-effectiveness of combinatorial pharmacogenomic testing for depression from the Canadian public payer perspective.

Pharmacogenomics 2020 06 17;21(8):521-531. Epub 2020 Apr 17.

Myriad Genetics Inc., Salt Lake City, UT 84108, USA.

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http://dx.doi.org/10.2217/pgs-2020-0012DOI Listing
June 2020

Advances in Identifying and Characterizing the Human Proteome.

J Proteome Res 2019 12;18(12):4079-4084

Institute for Systems Biology, Departments of Computational Medicine & Bioinformatics, Internal Medicine, and Human Genetics & School of Public Health , University of Michigan.

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http://dx.doi.org/10.1021/acs.jproteome.9b00745DOI Listing
December 2019

Simplified high yield TAILS terminomics using a new HPG-ALD 800K-2000 polymer with precipitation.

Methods Enzymol 2019 13;626:429-446. Epub 2019 Aug 13.

Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada; Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.07.030DOI Listing
June 2020

The active contribution of OPCs to neuroinflammation is mediated by LRP1.

Acta Neuropathol 2020 02 24;139(2):365-382. Epub 2019 Sep 24.

Department of Neuroscience, Center for Brain Immunology and Glia, School of Medicine, University of Virginia, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1007/s00401-019-02073-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994364PMC
February 2020

Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase.

J Biol Chem 2019 08 19;294(35):12866-12879. Epub 2019 Jul 19.

Centre for Blood Research, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.

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http://dx.doi.org/10.1074/jbc.RA119.009584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721938PMC
August 2019

Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions.

J Med Chem 2019 08 18;62(15):7185-7209. Epub 2019 Jul 18.

Infection and Immunity Program, Biomedicine Discovery Institute and Department of Microbiology , Monash University , Clayton Campus , Clayton , VIC 3800 , Australia.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00757DOI Listing
August 2019

Prediction of bacterial E3 ubiquitin ligase effectors using reduced amino acid peptide fingerprinting.

PeerJ 2019 7;7:e7055. Epub 2019 Jun 7.

Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, United States of America.

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http://dx.doi.org/10.7717/peerj.7055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557245PMC
June 2019

Matrix metalloproteinases in the CNS: interferons get nervous.

Cell Mol Life Sci 2019 Aug 4;76(16):3083-3095. Epub 2019 Jun 4.

Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada.

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http://dx.doi.org/10.1007/s00018-019-03171-9DOI Listing
August 2019

Persistent Salmonella enterica Serovar Typhimurium Infection Induces Protease Expression During Intestinal Fibrosis.

Inflamm Bowel Dis 2019 09;25(10):1629-1643

Institute of Medical Microbiology and Hospital Epidemiology and German Center for Infection Research (DZIF), Partner Site Hannover, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1093/ibd/izz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749888PMC
September 2019

Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer.

Pathol Res Pract 2019 Jun 2;215(6):152369. Epub 2019 Mar 2.

Laval University Cancer Research Center and Research Center of the Centre Hospitalier Universitaire (CHU) de Québec, Ville de Québec, QC, G1R 3S3, Canada.

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http://dx.doi.org/10.1016/j.prp.2019.02.019DOI Listing
June 2019

Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods.

J Proteome Res 2018 12;17(12):4023-4030

Institute for Systems Biology, Departments of Computational Medicine & Bioinformatics, Internal Medicine, and Human Genetics & School of Public Health, University of Michigan.

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http://dx.doi.org/10.1021/acs.jproteome.8b00885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288998PMC
December 2018

Precision Peptide Sequencing Using Mirror Proteases of Ac-LysargiNase and Trypsin for Large-scale Proteomics.

Mol Cell Proteomics 2019 04 8;18(4):773-785. Epub 2019 Jan 8.

§State Key Laboratory of Proteomics; Beijing Proteome Research Center; National Center for Protein Sciences Beijing; Beijing Institute of Lifeomics, Beijing 102206, China;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.TIR118.00091
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http://dx.doi.org/10.1074/mcp.TIR118.000918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442358PMC
April 2019

Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.

J Med Chem 2019 01 4;62(2):622-640. Epub 2019 Jan 4.

Department of Microbiology, Biomedicine Discovery Institute , Monash University, Clayton , Melbourne , VIC 3800 , Australia.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01310DOI Listing
January 2019

Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma.

J Endocrinol 2019 01;240(1):27-39

Departments of Cellular and Physiological Sciences and Obstetrics and Gynaecology, The University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1530/JOE-18-0479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347282PMC
January 2019

Global Profiling of Proteolysis from the Mitochondrial Amino Terminome during Early Intrinsic Apoptosis Prior to Caspase-3 Activation.

J Proteome Res 2018 12 29;17(12):4279-4296. Epub 2018 Oct 29.

Michael Smith Laboratories , University of British Columbia , Vancouver , British Columbia , V6T 1Z4 , Canada.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00675
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http://dx.doi.org/10.1021/acs.jproteome.8b00675DOI Listing
December 2018

Highlight: Frontiers in Proteolysis.

Biol Chem 2018 11;399(12):1351

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3.

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http://dx.doi.org/10.1515/hsz-2018-0401DOI Listing
November 2018

Improving network inference algorithms using resampling methods.

BMC Bioinformatics 2018 Oct 12;19(1):376. Epub 2018 Oct 12.

Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, USA.

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http://dx.doi.org/10.1186/s12859-018-2402-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186128PMC
October 2018

TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations.

Am J Physiol Lung Cell Mol Physiol 2018 12 4;315(6):L1003-L1014. Epub 2018 Oct 4.

Division of Respiratory Medicine and National Institute for Health Research Nottingham Biomedical Research Centre Respiratory Theme, University of Nottingham , Nottingham , United Kingdom.

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http://dx.doi.org/10.1152/ajplung.00175.2018DOI Listing
December 2018

Launching the C-HPP neXt-CP50 Pilot Project for Functional Characterization of Identified Proteins with No Known Function.

J Proteome Res 2018 12 29;17(12):4042-4050. Epub 2018 Nov 29.

Centre for Blood Research, Departments of Oral Biological & Medical Sciences and Biochemistry & Molecular Biology, Faculty of Dentistry , University of British Columbia , Vancouver , British Columbia V6T 1Z3 , Canada.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00383
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http://dx.doi.org/10.1021/acs.jproteome.8b00383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693327PMC
December 2018

C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

Nat Commun 2018 06 20;9(1):2416. Epub 2018 Jun 20.

Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, 4.401-2350 Health Sciences Mall, Vancouver, V6T 1Z3, BC, Canada.

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http://dx.doi.org/10.1038/s41467-018-04717-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010466PMC
June 2018

Species-specific transcriptomic network inference of interspecies interactions.

ISME J 2018 08 24;12(8):2011-2023. Epub 2018 May 24.

Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.

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http://dx.doi.org/10.1038/s41396-018-0145-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052077PMC
August 2018

Melanocyte development in the mouse tail epidermis requires the Adamts9 metalloproteinase.

Pigment Cell Melanoma Res 2018 11 5;31(6):693-707. Epub 2018 Jun 5.

Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/pcmr.12711DOI Listing
November 2018

TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by -glycosylation.

J Biol Chem 2018 05 28;293(20):7629-7644. Epub 2018 Mar 28.

From the Department of Cellular and Molecular Medicine, Centre for Glycomics, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark and

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http://dx.doi.org/10.1074/jbc.RA118.001978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961060PMC
May 2018

Identification of Protease Cleavage Sites and Substrates in Cancer by Carboxy-TAILS (C-TAILS).

Methods Mol Biol 2018 ;1731:15-28

Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/978-1-4939-7595-2_2DOI Listing
January 2019

Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification.

Chem Rev 2018 02 21;118(3):1137-1168. Epub 2017 Dec 21.

Life Sciences Institute, Department of Oral Biological and Medical Sciences, and ‡Department of Biochemistry and Molecular Biology, University of British Columbia , Vancouver, British Columbia V6T 1Z4, Canada.

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http://dx.doi.org/10.1021/acs.chemrev.7b00120DOI Listing
February 2018

Advances in the Chromosome-Centric Human Proteome Project: looking to the future.

Expert Rev Proteomics 2017 12 10;14(12):1059-1071. Epub 2017 Nov 10.

f Centre for Blood Research, Departments of Oral Biological & Medical Sciences, and Biochemistry & Molecular Biology, Faculty of Dentistry , University of British Columbia , Vancouver , Canada.

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http://dx.doi.org/10.1080/14789450.2017.1394189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158320PMC
December 2017

Progress on the HUPO Draft Human Proteome: 2017 Metrics of the Human Proteome Project.

J Proteome Res 2017 12 9;16(12):4281-4287. Epub 2017 Oct 9.

Institute for Systems Biology , 401 Terry Avenue North, Seattle, Washington 98109-5263, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872831PMC
December 2017

Overview of transcriptomic analysis of all human proteases, non-proteolytic homologs and inhibitors: Organ, tissue and ovarian cancer cell line expression profiling of the human protease degradome by the CLIP-CHIP™ DNA microarray.

Biochim Biophys Acta Mol Cell Res 2017 Nov 7;1864(11 Pt B):2210-2219. Epub 2017 Aug 7.

Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.08.004DOI Listing
November 2017

Can we predict protein from mRNA levels?

Nature 2017 07;547(7664):E19-E20

Department of Statistics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nature22293DOI Listing
July 2017

Aging-associated modifications of collagen affect its degradation by matrix metalloproteinases.

Matrix Biol 2018 01 17;65:30-44. Epub 2017 Jun 17.

Department of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, B.C. V6T 1Z3, Canada; Centre for Blood Research, University of British Columbia, Vancouver, B.C. V6T 1Z3, Canada; Department of Biochemistry & Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, B.C. V6T 1Z3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2017.06.004DOI Listing
January 2018

New intracellular activities of matrix metalloproteinases shine in the moonlight.

Biochim Biophys Acta Mol Cell Res 2017 Nov 16;1864(11 Pt A):2043-2055. Epub 2017 May 16.

Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Blood Research, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada; Department of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.05.013DOI Listing
November 2017

Sharpening Host Defenses during Infection: Proteases Cut to the Chase.

Mol Cell Proteomics 2017 04 8;16(4 suppl 1):S161-S171. Epub 2017 Feb 8.

¶Department of Biochemistry & Molecular Biology,

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http://dx.doi.org/10.1074/mcp.O116.066456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393396PMC
April 2017

Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X) and (X)K/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics.

J Proteome Res 2017 02 2;16(2):852-861. Epub 2016 Dec 2.

Centre for Blood Research, Department of Oral Biological and Medical Sciences, and Department of Biochemistry and Molecular Biology, University of British Columbia , Vancouver V6T 1Z3, BC, Canada.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.6b00825
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http://dx.doi.org/10.1021/acs.jproteome.6b00825DOI Listing
February 2017

Interactome disassembly during apoptosis occurs independent of caspase cleavage.

Mol Syst Biol 2017 01 12;13(1):906. Epub 2017 Jan 12.

Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293159PMC
http://dx.doi.org/10.15252/msb.20167067DOI Listing
January 2017

Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury.

J Exp Med 2017 02 19;214(2):285-296. Epub 2016 Dec 19.

Center for Brain Immunology and Glia (BIG), University of Virginia, Charlottesville, VA 22908

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http://dx.doi.org/10.1084/jem.20161982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5294864PMC
February 2017

Bayesian Model Averaging for Ensemble-Based Estimates of Solvation-Free Energies.

J Phys Chem B 2017 04 4;121(15):3458-3472. Epub 2017 Jan 4.

Division of Applied Mathematics, Brown University , Providence, Rhode Island 02912, United States.

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http://dx.doi.org/10.1021/acs.jpcb.6b09198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398953PMC
April 2017

Progress in the Chromosome-Centric Human Proteome Project as Highlighted in the Annual Special Issue IV.

J Proteome Res 2016 11;15(11):3945-3950

Departments of Computational Medicine & Bioinformatics, Internal Medicine, and Human Genetics and School of Public Health, University of Michigan.

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http://dx.doi.org/10.1021/acs.jproteome.6b00803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129621PMC
November 2016

Metrics for the Human Proteome Project 2016: Progress on Identifying and Characterizing the Human Proteome, Including Post-Translational Modifications.

J Proteome Res 2016 11 20;15(11):3951-3960. Epub 2016 Sep 20.

Institute for Systems Biology , 401 Terry Avenue North, Seattle, Washington 98109-5263, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129622PMC
November 2016

Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity.

Philos Trans A Math Phys Eng Sci 2016 Oct;374(2079)

Centre for Blood Research, University of British Columbia, Vancouver, BC Canada V6T 1Z3 Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC Canada V6T 1Z3 Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC Canada V6T 1Z3

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http://dx.doi.org/10.1098/rsta.2015.0372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031638PMC
October 2016

Traumatic brain injury induced matrix metalloproteinase2 cleaves CXCL12α (stromal cell derived factor 1α) and causes neurodegeneration.

Brain Behav Immun 2017 Jan 7;59:190-199. Epub 2016 Sep 7.

Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2016.09.002DOI Listing
January 2017

iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.

Eur J Immunol 2016 12 28;46(12):2737-2748. Epub 2016 Sep 28.

Program in Inflammation and Autoimmunity, Hospital for Special Surgery, 535 East 71 St., New York, NY 10021, USA.

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http://dx.doi.org/10.1002/eji.201646482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149455PMC
December 2016

Network analysis of transcriptomics expands regulatory landscapes in Synechococcus sp. PCC 7002.

Nucleic Acids Res 2016 Oct 27;44(18):8810-8825. Epub 2016 Aug 27.

Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA

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http://dx.doi.org/10.1093/nar/gkw737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062996PMC
October 2016

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.

Cell Rep 2016 08 28;16(6):1762-1773. Epub 2016 Jul 28.

Centre for Blood Research, Life Sciences Institute and Faculty of Dentistry, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.06.086DOI Listing
August 2016

Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2).

Matrix Biol 2017 05 26;59:23-38. Epub 2016 Jul 26.

Centre for Blood Research, Departments of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2016.07.006DOI Listing
May 2017

Novel grooved substrata stimulate macrophage fusion, CCL2 and MMP-9 secretion.

J Biomed Mater Res A 2016 09 10;104(9):2243-54. Epub 2016 May 10.

Department of Oral Biological & Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1002/jbm.a.35757DOI Listing
September 2016

Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14.

Data Brief 2016 Jun 22;7:299-310. Epub 2016 Feb 22.

Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.dib.2016.02.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777984PMC
June 2016

Prediction of multi-drug resistance transporters using a novel sequence analysis method.

F1000Res 2015 9;4:60. Epub 2015 Mar 9.

Biological Sciences, Pacific Northwest National Laboratory, Washington, WA, 99352, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743146PMC
http://dx.doi.org/10.12688/f1000research.6200.2DOI Listing
February 2016

TAILS N-terminomic and proteomic datasets of healthy human dental pulp.

Data Brief 2015 Dec 16;5:542-8. Epub 2015 Oct 16.

Centre for Blood Research, The Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada ; Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada ; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.dib.2015.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625376PMC
December 2015

Novel N-terminal and Lysine Methyltransferases That Target Translation Elongation Factor 1A in Yeast and Human.

Mol Cell Proteomics 2016 Jan 6;15(1):164-76. Epub 2015 Nov 6.

From the ‡Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, New South Wales, 2052, Australia;

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http://dx.doi.org/10.1074/mcp.M115.052449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762513PMC
January 2016

Positional proteomics in the era of the human proteome project on the doorstep of precision medicine.

Biochimie 2016 Mar 14;122:110-8. Epub 2015 Nov 14.

Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2015.10.018DOI Listing
March 2016

Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses.

Matrix Biol 2016 Jan 25;49:37-60. Epub 2015 Sep 25.

Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2015.09.003DOI Listing
January 2016

Recent Advances in the Chromosome-Centric Human Proteome Project: Missing Proteins in the Spot Light.

J Proteome Res 2015 Sep;14(9):3409-14

Department of Chemical Biology, Northeastern University , Boston, Massachusetts 02115, United States.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.5b00785
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http://dx.doi.org/10.1021/acs.jproteome.5b00785DOI Listing
September 2015

The Human Dental Pulp Proteome and N-Terminome: Levering the Unexplored Potential of Semitryptic Peptides Enriched by TAILS to Identify Missing Proteins in the Human Proteome Project in Underexplored Tissues.

J Proteome Res 2015 Sep 14;14(9):3568-82. Epub 2015 Aug 14.

Centre for Blood Research, University of British Columbia , Vancouver, British Columbia V6T 1Z3, Canada.

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http://dx.doi.org/10.1021/acs.jproteome.5b00579DOI Listing
September 2015

Protein Termini and Their Modifications Revealed by Positional Proteomics.

ACS Chem Biol 2015 Aug 6;10(8):1754-64. Epub 2015 Jul 6.

†Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1021/acschembio.5b00189DOI Listing
August 2015

The path of no return--Truncated protein N-termini and current ignorance of their genesis.

Proteomics 2015 Jul 15;15(14):2547-52. Epub 2015 Jun 15.

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British, Columbia, Canada.

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http://dx.doi.org/10.1002/pmic.201500043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736679PMC
July 2015

Cysteine Cathepsins Activate ELR Chemokines and Inactivate Non-ELR Chemokines.

J Biol Chem 2015 May 1;290(22):13800-11. Epub 2015 Apr 1.

From the Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, SI-1000 Ljubljana, Slovenia, the Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, SI-1000 Ljubljana, Slovenia, and the Faculty of Chemistry and Chemical Technology, University of Ljubljana, SI-1000 Ljubljana, Slovenia

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http://dx.doi.org/10.1074/jbc.M115.638395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447957PMC
May 2015