Publications by authors named "Christopher M Koth"

30Publications

Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7.

Cell Chem Biol 2020 Mar 12;27(3):306-313.e4. Epub 2019 Nov 12.

Department of Chemistry, Imperial College London, London W12 0BZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083225PMC
March 2020

A Flexible and Scalable High-Throughput Platform for Recombinant Membrane Protein Production.

Methods Mol Biol 2019 ;2025:389-402

Department of Structural Biology, Genentech Inc., South San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9624-7_18DOI Listing
March 2020

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin.

Cell 2019 02 17;176(4):702-715.e14. Epub 2019 Jan 17.

Department of Structural Biology, Genentech, South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.12.018DOI Listing
February 2019

Voltage-gated sodium channels viewed through a structural biology lens.

Curr Opin Struct Biol 2017 08 15;45:74-84. Epub 2016 Dec 15.

Department of Structural Biology, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2016.11.022DOI Listing
August 2017

Structural analysis of bacterial ABC transporter inhibition by an antibody fragment.

Structure 2015 Apr 5;23(4):713-23. Epub 2015 Mar 5.

Department of Structural Biology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2015.01.020DOI Listing
April 2015

Molecular basis for negative regulation of the glucagon receptor.

Proc Natl Acad Sci U S A 2012 Sep 20;109(36):14393-8. Epub 2012 Aug 20.

Department of Structural Biology, Molecular Biology, Antibody Engineering, Protein Chemistry, and Early Discovery Biochemistry, Genentech Inc, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1073/pnas.1206734109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437825PMC
September 2012

Strategies for the cloning and expression of membrane proteins.

Adv Protein Chem Struct Biol 2009 27;76:43-86. Epub 2009 Nov 27.

Department of Structural Biology, Genentech, South San Francisco, California 94080, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S187616230876002
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http://dx.doi.org/10.1016/S1876-1623(08)76002-4DOI Listing
November 2010

Structural proteomics of membrane proteins: a survey of published techniques and design of a rational high throughput strategy.

Methods Mol Biol 2008 ;426:277-95

American Type Culture Collection, Manassas, VA, USA.

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http://dx.doi.org/10.1007/978-1-60327-058-8_18DOI Listing
August 2008

A robust purification strategy to accelerate membrane proteomics.

Methods 2007 Apr;41(4):381-7

Banting and Best Department of Medical Research, University of Toronto, 112 College Street, Toronto, ON, Canada M5G 1L6.

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http://dx.doi.org/10.1016/j.ymeth.2006.08.009DOI Listing
April 2007

Crystal structure of the CorA Mg2+ transporter.

Nature 2006 Apr;440(7085):833-7

Department of Medical Biophysics, University of Toronto, 112 College Street, Toronto, Ontario M5G 1L6, Canada.

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http://dx.doi.org/10.1038/nature04642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836678PMC
April 2006

High-throughput production of prokaryotic membrane proteins.

J Struct Funct Genomics 2005 ;6(1):33-50

Ontario Center for Structural Proteomics, University of Toronto, 112 College St., Toronto, Ontario, Canada.

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http://link.springer.com/content/pdf/10.1007/s10969-005-1363
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http://link.springer.com/10.1007/s10969-005-1363-5
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http://dx.doi.org/10.1007/s10969-005-1363-5DOI Listing
February 2006

Activation of Notch signaling pathway precedes heart regeneration in zebrafish.

Proc Natl Acad Sci U S A 2003 Sep 8;100 Suppl 1:11889-95. Epub 2003 Aug 8.

Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1834204100
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http://dx.doi.org/10.1073/pnas.1834204100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC304103PMC
September 2003

MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb.

Nat Cell Biol 2003 Jun;5(6):513-9

The Salk Institute for Biological Studies, Gene Expression Laboratory, 10010 North Torrey Pines Road, La Jolla, California 92037-1099, USA.

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http://dx.doi.org/10.1038/ncb989DOI Listing
June 2003

The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10.

Development 2002 Nov;129(22):5161-70

The Salk Institute for Biological Studies, Gene Expression Laboratory, 10010 North Torrey Pines Road, La Jolla, CA 92037-1099. USA.

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November 2002