Christopher M Heaphy

Christopher M Heaphy

UNVERIFIED PROFILE

Are you Christopher M Heaphy?   Register this Author

Register author
Christopher M Heaphy

Christopher M Heaphy

Publications by authors named "Christopher M Heaphy"

Are you Christopher M Heaphy?   Register this Author

68Publications

1459Reads

31Profile Views

Surviving Telomere Attrition with the MiDAS Touch.

Trends Genet 2019 Nov 13;35(11):783-785. Epub 2019 Sep 13.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2019.08.008DOI Listing
November 2019

Mannose Receptor-positive Macrophage Infiltration Correlates with Prostate Cancer Onset and Metastatic Castration-resistant Disease.

Eur Urol Oncol 2019 Jul 19;2(4):429-436. Epub 2018 Oct 19.

Department of Oncology, Johns Hopkins School of Medicine and The Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.euo.2018.09.014DOI Listing
July 2019

ATRX Mutations in Pineal Parenchymal Tumors of Intermediate Differentiation.

J Neuropathol Exp Neurol 2019 May 27. Epub 2019 May 27.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnen/nlz050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640895PMC
May 2019

Incidentally detected pancreatic neuroendocrine microadenoma with lymph node metastasis.

Virchows Arch 2018 Nov 12;473(5):649-653. Epub 2018 Jul 12.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00428-018-2407-0DOI Listing
November 2018

Genetic alterations associated with ALTered telomeres.

Oncotarget 2018 Sep 18;9(73):33739-33740. Epub 2018 Sep 18.

Christopher M. Heaphy: Departments of Pathology and Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.26111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173459PMC
September 2018

Racial differences in maternal and umbilical cord blood leukocyte telomere length and their correlations.

Cancer Causes Control 2018 08 6;29(8):759-767. Epub 2018 Jul 6.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD, 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10552-018-1054-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083880PMC
August 2018

Cocaine use may induce telomere shortening in individuals with HIV infection.

Prog Neuropsychopharmacol Biol Psychiatry 2018 06 2;84(Pt A):11-17. Epub 2018 Feb 2.

Department of Radiology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pnpbp.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880737PMC
June 2018

Alternative lengthening of telomeres and ATRX/DAXX loss can be reliably detected in FNAs of pancreatic neuroendocrine tumors.

Cancer Cytopathol 2017 Jul 3;125(7):544-551. Epub 2017 Apr 3.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cncy.21857
Publisher Site
http://dx.doi.org/10.1002/cncy.21857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511056PMC
July 2017

Influence of In Utero Maternal and Neonate Factors on Cord Blood Leukocyte Telomere Length: Clues to the Racial Disparity in Prostate Cancer?

Prostate Cancer 2016 14;2016:3691650. Epub 2016 Dec 14.

Department of Pathology, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 401 N. Broadway, Baltimore, MD 21287, USA; Department of Urology and the James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2016/3691650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192337PMC
December 2016

Frequent alternative lengthening of telomeres and ATRX loss in adult NF1-associated diffuse and high-grade astrocytomas.

Acta Neuropathol 2016 11 20;132(5):761-763. Epub 2016 Sep 20.

Department of Pathology, Johns Hopkins University, Sheikh Zayed Tower, Room M2101, 1800 Orleans Street, Baltimore, MD, 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-016-1619-0DOI Listing
November 2016

Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.

Hum Pathol 2016 10 21;56:93-100. Epub 2016 Jun 21.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Department of Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2016.06.006DOI Listing
October 2016

High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors.

Hum Pathol 2016 08 13;54:106-12. Epub 2016 Apr 13.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Urology, James Buchanan Brady Urological Institute at Johns Hopkins, Baltimore, MD. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2016.03.015DOI Listing
August 2016

Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.

J Biol Chem 2016 Apr 7;291(18):9690-9. Epub 2016 Mar 7.

From the Department of Pathology, the Sidney Kimmel Comprehensive Cancer Center, and the Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M115.707612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850306PMC
April 2016

Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells.

Cancer Prev Res (Phila) 2015 Aug 19;8(8):737-42. Epub 2015 May 19.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1940-6207.CAPR-15-0097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526348PMC
August 2015

Telomere length alterations unique to invasive lobular carcinoma.

Hum Pathol 2015 Aug 22;46(8):1197-203. Epub 2015 May 22.

Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231; Department of Oncology, The Johns Hopkins Hospital, Baltimore, MD 21231. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2015.05.001DOI Listing
August 2015

Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.

Curr Protoc Cytom 2015 Jul 1;73:12.40.1-31. Epub 2015 Jul 1.

University of Pittsburgh Cancer Institute, Hillman Cancer Center, Pittsburgh, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142956.cy1240s73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862373PMC
July 2015

Telomere length as a risk factor for hereditary prostate cancer.

Prostate 2014 Apr 28;74(4):359-64. Epub 2013 Nov 28.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.22755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479489PMC
April 2014

Alternative lengthening of telomeres predicts site of origin in neuroendocrine tumor liver metastases.

J Am Coll Surg 2014 Apr 10;218(4):628-35. Epub 2014 Jan 10.

Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University, Baltimore, MD; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jamcollsurg.2014.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332797PMC
April 2014

Prostate cancer cell telomere length variability and stromal cell telomere length as prognostic markers for metastasis and death.

Cancer Discov 2013 Oct 18;3(10):1130-41. Epub 2013 Jun 18.

1Department of Pathology; 2James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine; 3Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health; 4Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland; Departments of 5Nutrition and 6Epidemiology, Harvard School of Public Health; and 7Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; 8Department of Pathology, Kyungpook National University School of Medicine, Daegu, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-13-0135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797255PMC
October 2013

Coordinate regulation between expression levels of telomere-binding proteins and telomere length in breast carcinomas.

Cancer Med 2012 Oct 24;1(2):165-75. Epub 2012 Jul 24.

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine Albuquerque, New Mexico, 87131, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cam4.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544452PMC
October 2012

The potential utility of telomere-related markers for cancer diagnosis.

J Cell Mol Med 2011 Jun;15(6):1227-38

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1582-4934.2011.01284.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373325PMC
June 2011

Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias.

Mod Pathol 2011 Feb 24;24(2):256-66. Epub 2010 Sep 24.

Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2010.181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166222PMC
February 2011

Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes.

Mod Pathol 2011 Feb 5;24(2):194-200. Epub 2010 Nov 5.

Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2010.198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416483PMC
February 2011

Organ-wide telomeric status in diseased and disease-free prostatic tissues.

Prostate 2010 Sep;70(13):1471-9

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.21182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920907PMC
September 2010

Mammary field cancerization: molecular evidence and clinical importance.

Breast Cancer Res Treat 2009 Nov 15;118(2):229-39. Epub 2009 Aug 15.

Department of Pathology, The Johns Hopkins Medical Institutions, 411 N. Caroline St., Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-009-0504-0DOI Listing
November 2009

The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression.

Mod Pathol 2009 Nov 4;22(11):1423-31. Epub 2009 Sep 4.

Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2009.125DOI Listing
November 2009

Genomic instability demonstrates similarity between DCIS and invasive carcinomas.

Breast Cancer Res Treat 2009 Sep 11;117(1):17-24. Epub 2008 Sep 11.

Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, 87131-0001, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-008-0165-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728157PMC
September 2009

Telomere DNA content predicts breast cancer-free survival interval.

Clin Cancer Res 2007 Dec;13(23):7037-43

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131-0001, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-07-0432DOI Listing
December 2007

Diagnostic significance of allelic imbalance in cancer.

Expert Opin Med Diagn 2007 Oct;1(2):159-68

Graduate Research Assistant, University of New Mexico School of Medicine, Department of Biochemistry and Molecular Biology, MSC08 4670, 1 University of New Mexico, Albuquerque, New Mexico 87131-0001, USA +1 505 272 5090 ; +1 505 272 6587 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/17530059.1.2.159DOI Listing
October 2007

Telomeres: prognostic markers for solid tumors.

Int J Cancer 2006 Nov;119(10):2255-60

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, 87131-0001, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.22120DOI Listing
November 2006

Telomere content correlates with stage and prognosis in breast cancer.

Breast Cancer Res Treat 2006 Sep 3;99(2):193-202. Epub 2006 Jun 3.

Department of Biochemistry and Molecular Biology, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s10549-006-9204
Web Search
http://link.springer.com/10.1007/s10549-006-9204-1
Publisher Site
http://dx.doi.org/10.1007/s10549-006-9204-1DOI Listing
September 2006

Telomere DNA content and allelic imbalance demonstrate field cancerization in histologically normal tissue adjacent to breast tumors.

Int J Cancer 2006 Jul;119(1):108-16

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131-0001, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.21815DOI Listing
July 2006

Protease nexin-1 expression is altered in human breast cancer.

Cancer Cell Int 2006 May 31;6:16. Epub 2006 May 31.

Department of Biochemistry and Molecular Biology, University of New Mexico, School of Medicine, MSC08 4670, Albuquerque, New Mexico 87131, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2867-6-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501059PMC
May 2006

Association between cancer-free survival and telomere DNA content in prostate tumors.

J Urol 2005 Feb;173(2):610-4

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131-0001, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.ju.0000143195.49685.ceDOI Listing
February 2005

Chemiluminescent measurement of telomere DNA content in biopsies.

Biotechniques 2002 Jul;33(1):144-6, 148

University of New Mexico Health Sciences Center, Albuquerque 87131-5221, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2144/02331md02DOI Listing
July 2002