Christopher M Counter

Christopher M Counter

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A model for RAS mutation patterns in cancers: finding the sweet spot.

Nat Rev Cancer 2018 12;18(12):767-777

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA.

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http://www.nature.com/articles/s41568-018-0076-6
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http://dx.doi.org/10.1038/s41568-018-0076-6DOI Listing
December 2018

Copper Chelation as Targeted Therapy in a Mouse Model of Oncogenic BRAF-Driven Papillary Thyroid Cancer.

Clin Cancer Res 2018 09 31;24(17):4271-4281. Epub 2018 Jul 31.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-3705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125179PMC
September 2018

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

Nat Commun 2018 09 7;9(1):3646. Epub 2018 Sep 7.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, DUMC-3813, Durham, NC, 27713, USA.

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http://dx.doi.org/10.1038/s41467-018-05692-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128905PMC
September 2018

Wnt signaling suppresses MAPK-driven proliferation of intestinal stem cells.

J Clin Invest 2018 08 30;128(9):3806-3812. Epub 2018 Jul 30.

Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore.

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https://www.jci.org/articles/view/99325
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http://dx.doi.org/10.1172/JCI99325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118584PMC
August 2018

Copper Chelation Inhibits BRAF-Driven Melanomagenesis and Counters Resistance to BRAF and MEK1/2 Inhibitors.

Cancer Res 2017 11 6;77(22):6240-6252. Epub 2017 Oct 6.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690876PMC
November 2017

Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.

PLoS One 2016 2;11(12):e0167205. Epub 2016 Dec 2.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167205PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135096PMC
June 2017

Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance.

Nat Commun 2017 06 8;8:15617. Epub 2017 Jun 8.

Department of Pharmacology and Cancer Biology, Duke University, Durham, North California 27710, USA.

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http://dx.doi.org/10.1038/ncomms15617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472712PMC
June 2017

Wild-Type Hras Suppresses the Earliest Stages of Tumorigenesis in a Genetically Engineered Mouse Model of Pancreatic Cancer.

PLoS One 2015 9;10(10):e0140253. Epub 2015 Oct 9.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America; Department of Radiation Oncology, Duke University Medical Center, Durham, NC, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140253PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599940PMC
May 2016

Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S.

PLoS One 2015 22;10(4):e0123918. Epub 2015 Apr 22.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America; Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123918PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406447PMC
April 2016

A Genetic Porcine Model of Cancer.

PLoS One 2015 1;10(7):e0128864. Epub 2015 Jul 1.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America; Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128864PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488487PMC
April 2016

Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth.

Mol Cell 2015 Feb;57(3):537-51

Department of Microbiology, Immunology and Cancer Biology, University of Virginia Health System, Charlottesville, VA 22908, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393013PMC
February 2015

Decreased tumorigenesis in mice with a Kras point mutation at C118.

Nat Commun 2014 Nov 14;5:5410. Epub 2014 Nov 14.

1] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA [2] Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.nature.com/articles/ncomms6410
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http://dx.doi.org/10.1038/ncomms6410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234187PMC
November 2014

Copper is required for oncogenic BRAF signalling and tumorigenesis.

Nature 2014 May 9;509(7501):492-6. Epub 2014 Apr 9.

1] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA [2] Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/nature13180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138975PMC
May 2014

Cell cycle regulated phosphorylation of the telomere-associated protein TIN2.

PLoS One 2013 16;8(8):e71697. Epub 2013 Aug 16.

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, DUMC, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071697PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745427PMC
April 2014

Snm1B interacts with PSF2.

PLoS One 2012 26;7(11):e49626. Epub 2012 Nov 26.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049626PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506659PMC
May 2013

Rare codons regulate KRas oncogenesis.

Curr Biol 2013 Jan 13;23(1):70-5. Epub 2012 Dec 13.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09609822120137
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http://dx.doi.org/10.1016/j.cub.2012.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567844PMC
January 2013

Targeting eNOS in pancreatic cancer.

Cancer Res 2012 Sep 27;72(17):4472-82. Epub 2012 Jun 27.

Departments of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749841PMC
September 2012

A novel role for copper in Ras/mitogen-activated protein kinase signaling.

Mol Cell Biol 2012 Apr 30;32(7):1284-95. Epub 2012 Jan 30.

Department of Pharmacology and Cancer Biology, Duke University Medical School, Durham, North Carolina, USA.

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http://dx.doi.org/10.1128/MCB.05722-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302449PMC
April 2012

PinX1 localizes to telomeres and stabilizes TRF1 at mitosis.

Mol Cell Biol 2012 Apr 13;32(8):1387-95. Epub 2012 Feb 13.

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1128/MCB.05641-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318592PMC
April 2012

Breaking up is hard to do: RalA, mitochondrial fission and cancer.

Small GTPases 2011 Nov;2(6):329-333

Department of Pharmacology and Cancer Biology; Department of Radiation Oncology; Duke University Medical Center; Durham, NC USA.

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http://dx.doi.org/10.4161/sgtp.18284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337163PMC
November 2011

RALA and RALBP1 regulate mitochondrial fission at mitosis.

Nat Cell Biol 2011 Aug 7;13(9):1108-15. Epub 2011 Aug 7.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.nature.com/articles/ncb2310
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http://dx.doi.org/10.1038/ncb2310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167028PMC
August 2011

cPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatis.

J Biol Chem 2010 Jul 7;285(28):21625-35. Epub 2010 May 7.

Departments of Molecular Genetics and Microbiology, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M110.103010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898388PMC
July 2010

Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis.

Mol Cancer Res 2010 Feb 9;8(2):223-31. Epub 2010 Feb 9.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, DUMC-3813, Durham, NC 27710, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-09-0189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824780PMC
February 2010

Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA.

Mol Cell Biol 2010 Jan 9;30(2):508-23. Epub 2009 Nov 9.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1128/MCB.00916-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798468PMC
January 2010

ELR+ CXC chemokines and oncogenic Ras-mediated tumorigenesis.

Carcinogenesis 2009 Nov 5;30(11):1841-7. Epub 2009 Oct 5.

Department of Pharmacology and Cancer Biology, DUMC, Durham, NC 27710, USA.

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http://dx.doi.org/10.1093/carcin/bgp198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783001PMC
November 2009

POT1 association with TRF2 regulates telomere length.

Mol Cell Biol 2009 Oct 3;29(20):5611-9. Epub 2009 Aug 3.

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1128/MCB.00286-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756888PMC
October 2009

Distinct functions of POT1 at telomeres.

Mol Cell Biol 2008 Sep 2;28(17):5251-64. Epub 2008 Jun 2.

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://mcb.asm.org/content/28/17/5251.full.pdf
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http://mcb.asm.org/cgi/doi/10.1128/MCB.00048-08
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http://dx.doi.org/10.1128/MCB.00048-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519730PMC
September 2008

Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells.

Mol Biol Cell 2008 Sep 18;19(9):3793-800. Epub 2008 Jun 18.

Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.

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http://dx.doi.org/10.1091/mbc.e08-02-0184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526684PMC
September 2008

The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2.

J Biol Chem 2008 Aug 1;283(35):23671-6. Epub 2008 Jul 1.

Departments of Pharmacology and Cancer Biology and Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1074/jbc.M800388200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259752PMC
August 2008

Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and ras effector expression to human tumor cell growth.

Methods Enzymol 2006 ;407:556-74

Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)07045-XDOI Listing
June 2008

A genetically defined normal human somatic cell system to study ras oncogenesis in vivo and in vitro.

Methods Enzymol 2006 ;407:637-47

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)07050-3DOI Listing
June 2008

A method to generate genetically defined tumors in pigs.

Methods Enzymol 2008 ;439:39-51

Department of Pharmacology and Molecular Cancer Biology, Duke University, Durham, North Carolina, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S007668790700404
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http://dx.doi.org/10.1016/S0076-6879(07)00404-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688827PMC
June 2008

Genetic modeling of Ras-induced human rhabdomyosarcoma.

Methods Enzymol 2008 ;438:419-27

Department of Pediatrics, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.1016/S0076-6879(07)38028-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782627PMC
June 2008

Tumour maintenance is mediated by eNOS.

Nature 2008 Apr 16;452(7187):646-9. Epub 2008 Mar 16.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/nature06778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688829PMC
April 2008

Tethering telomeric double- and single-stranded DNA-binding proteins inhibits telomere elongation.

J Biol Chem 2008 Mar 3;283(11):6935-41. Epub 2008 Jan 3.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M708711200DOI Listing
March 2008

Oncogenic ras-induced expression of cytokines: a new target of anti-cancer therapeutics.

Mol Interv 2008 Feb;8(1):22-7

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1124/mi.8.1.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788125PMC
February 2008

Characterization of the porcine ATM gene: towards the generation of a novel non-murine animal model for Ataxia-Telangiectasia.

Gene 2007 Dec 30;405(1-2):27-35. Epub 2007 Aug 30.

Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1201 W. Gregory Dr., Urbana, IL 61801, USA.

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http://dx.doi.org/10.1016/j.gene.2007.08.014DOI Listing
December 2007

The PAX3-FKHR fusion gene of rhabdomyosarcoma cooperates with loss of p16INK4A to promote bypass of cellular senescence.

Cancer Res 2007 Jul;67(14):6691-9

Department of Pediatrics, Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3210DOI Listing
July 2007

Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

Genes Dev 2007 Jul;21(14):1714-9

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1101/gad.1549407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1920165PMC
July 2007

hSnm1B is a novel telomere-associated protein.

J Biol Chem 2006 Jun 10;281(22):15033-6. Epub 2006 Apr 10.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.C600038200DOI Listing
June 2006

Genetically engineered human cancer models utilizing mammalian transgene expression.

Cell Cycle 2006 May 15;5(10):1074-9. Epub 2006 May 15.

Department of Pharmacology and Molecular Cancer Biology, Duke University, Durham, North Carolina, USA.

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http://dx.doi.org/10.4161/cc.5.10.2734DOI Listing
May 2006

A network of genetic events sufficient to convert normal human cells to a tumorigenic state.

Cancer Res 2005 Nov;65(21):9824-8

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-1543DOI Listing
November 2005

Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance.

Cancer Cell 2005 Nov;8(5):381-92

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1016/j.ccr.2005.10.014DOI Listing
November 2005

Blood vessels engineered from human cells.

Lancet 2005 Jun 18-24;365(9477):2122-4

Duke University Medical Center, Duke University, Durham, NC, USA.

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http://dx.doi.org/10.1016/S0140-6736(05)66735-9DOI Listing
September 2005

Genetic modeling of human rhabdomyosarcoma.

Cancer Res 2005 Jun;65(11):4490-5

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-3194DOI Listing
June 2005

Activation of RalA is critical for Ras-induced tumorigenesis of human cells.

Cancer Cell 2005 Jun;7(6):533-45

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.ccr.2005.04.030DOI Listing
June 2005

Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR.

J Biol Chem 2004 Dec 20;279(50):51745-8. Epub 2004 Sep 20.

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina, 27710, USA.

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http://www.jbc.org/content/early/2004/09/20/jbc.M408131200.f
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http://www.jbc.org/lookup/doi/10.1074/jbc.M408131200
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http://dx.doi.org/10.1074/jbc.M408131200DOI Listing
December 2004

Loss of hPot1 function leads to telomere instability and a cut-like phenotype.

Curr Biol 2004 Dec;14(24):2264-70

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.cub.2004.12.031DOI Listing
December 2004

Genomics and clinical medicine: rationale for creating and effectively evaluating animal models.

Exp Biol Med (Maywood) 2004 Oct;229(9):866-75

Edward R. Madigan Laboratory, University of Illinois, 1201 West Gregory Drive, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1177/153537020422900902DOI Listing
October 2004

Leveling the playing field.

Mol Cell 2004 Aug;15(4):491-2

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.molcel.2004.08.014DOI Listing
August 2004

Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1.

Mol Cell Biol 2004 Apr;24(8):3552-61

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC381596PMC
http://dx.doi.org/10.1128/mcb.24.8.3552-3561.2004DOI Listing
April 2004

In vivo regulation of hTERT expression and telomerase activity by androgen.

J Urol 2003 Aug;170(2 Pt 1):615-8

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1097/01.ju.0000074653.22766.c8DOI Listing
August 2003

Human arteries engineered in vitro.

EMBO Rep 2003 Jun;4(6):633-8

Department of Anesthesiology and Department of Biomedical Engineering, Duke University Medical Center, Durham, NC 27710, USA.

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http://embor.embopress.org/cgi/doi/10.1038/sj.embor.embor847
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http://dx.doi.org/10.1038/sj.embor.embor847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319197PMC
June 2003

Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model.

J Biol Chem 2003 May 17;278(18):15951-7. Epub 2003 Feb 17.

Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1074/jbc.M211498200DOI Listing
May 2003

Putative telomere-recruiting domain in the catalytic subunit of human telomerase.

Mol Cell Biol 2003 May;23(9):3237-46

Departments of Pharmacology and Cancer Biology, Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153184PMC
http://dx.doi.org/10.1128/mcb.23.9.3237-3246.2003DOI Listing
May 2003

Telomere shortening in cultured autografts of patients with burns.

Lancet 2003 Apr;361(9366):1345-6

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736031304
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http://dx.doi.org/10.1016/S0140-6736(03)13042-5DOI Listing
April 2003

Mutational analysis defines a minimum level of telomerase activity required for tumourigenic growth of human cells.

Oncogene 2002 Oct;21(46):7121-5

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, NC 27710, USA.

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http://dx.doi.org/10.1038/sj.onc.1205860DOI Listing
October 2002

C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity.

Mol Cell Biol 2002 Sep;22(17):6234-46

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134020PMC
http://dx.doi.org/10.1128/mcb.22.17.6234-6246.2002DOI Listing
September 2002

Distinct requirements for Ras oncogenesis in human versus mouse cells.

Genes Dev 2002 Aug;16(16):2045-57

Department of Pharmacology, Division of Neurology, Duke University Medical Center, Durham North Carolina 27710, USA.

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http://dx.doi.org/10.1101/gad.993902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC186434PMC
August 2002

The nucleolar localization domain of the catalytic subunit of human telomerase.

J Biol Chem 2002 Jul 15;277(27):24764-70. Epub 2002 Apr 15.

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M201227200DOI Listing
July 2002

Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression.

Nat Biotechnol 2002 Jun;20(6):587-91

Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/nbt0602-587DOI Listing
June 2002