Christopher L Corless

Christopher L Corless

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Christopher L Corless

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Colorectal Cancer-Associated Spontaneous Tumor Lysis Syndrome: a Case Report and Review of the Current Literature.

J Gastrointest Cancer 2019 09;50(3):668-673

Knight Cancer Institute, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Rd L-586, Portland, OR, 97239, USA.

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http://dx.doi.org/10.1007/s12029-018-0102-7DOI Listing
September 2019

Loss of the PTCH1 tumor suppressor defines a new subset of plexiform fibromyxoma.

J Transl Med 2019 Jul 30;17(1):246. Epub 2019 Jul 30.

Division of Surgical Oncology, Department of Surgery, Moores Cancer Center, University of California, San Diego, UC San Diego Health Sciences, 3855 Health Sciences Drive, Room 2313, Mail Code 0987, La Jolla, CA, 92093-0987, USA.

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http://dx.doi.org/10.1186/s12967-019-1995-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668176PMC
July 2019

Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer.

Cold Spring Harb Mol Case Stud 2019 Apr 1;5(2). Epub 2019 Apr 1.

Department of Molecular and Medical Genetics, Oregon Health and Science University (OHSU) Portland, Oregon 97201, USA.

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http://dx.doi.org/10.1101/mcs.a003772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549569PMC
April 2019

Gastrointestinal stromal tumours of the oesophagus: a clinicopathological and molecular analysis of 27 cases.

Histopathology 2017 Nov 6;71(5):805-812. Epub 2017 Sep 6.

Department of Pathology and Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1111/his.13292DOI Listing
November 2017

Durable Response to Afatinib in Lung Adenocarcinoma Harboring NRG1 Gene Fusions.

J Thorac Oncol 2017 08 10;12(8):e107-e110. Epub 2017 May 10.

Knight Cancer Institute, Division of Hematology-Oncology, Oregon Health and Science University, Portland, Oregon. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864173035
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http://dx.doi.org/10.1016/j.jtho.2017.04.025DOI Listing
August 2017

Using molecular diagnostic testing to personalize the treatment of patients with gastrointestinal stromal tumors.

Expert Rev Mol Diagn 2017 May 27;17(5):445-457. Epub 2017 Mar 27.

a Portland VA Health Care System and OHSU Knight Cancer Institute , Portland , OR , USA.

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http://dx.doi.org/10.1080/14737159.2017.1308826DOI Listing
May 2017

Defining the Impact of Adjuvant Therapy in Molecularly Defined Subsets of Gastrointestinal Stromal Tumor : From Lumping to Splitting.

JAMA Oncol 2017 05;3(5):597-599

Dana-Farber Cancer Institute and Ludwig Center at Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaoncol.2016.5740DOI Listing
May 2017

Discordant Mutations in Paired Primary and Metastatic Endometrial Adenocarcinomas Identified by Semiconductor-Based Sequencing for Rapid Cancer Genotyping.

Reprod Sci 2016 11 11;23(11):1575-1579. Epub 2016 May 11.

Department of Pathology, Oregon Health & Science University, Portland, OR, USA Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR, USA Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA

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http://dx.doi.org/10.1177/1933719116648213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933108PMC
November 2016

Next-Generation Sequencing in Cancer Diagnostics.

J Mol Diagn 2016 11 21;18(6):813-816. Epub 2016 Sep 21.

Knight Diagnostic Laboratories, Oregon Health & Science University, Portland, Oregon. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.08.002DOI Listing
November 2016

A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing.

J Mol Diagn 2016 Mar 30;18(2):165-75. Epub 2015 Dec 30.

Division of Molecular & Genomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1016/j.jmoldx.2015.10.002DOI Listing
March 2016

Utility of BRAF V600E mutation-specific immunohistochemistry in detecting BRAF V600E-mutated gastrointestinal stromal tumors.

Am J Clin Pathol 2015 Nov;144(5):782-9

From the Robert J. Tomsich Pathology and Laboratory Medicine Institute, Department of Pathology, Cleveland Clinic, Cleveland, OH;

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http://dx.doi.org/10.1309/AJCPRK3V2EIIUPQZDOI Listing
November 2015

SDHC methylation in gastrointestinal stromal tumors (GIST): a case report.

BMC Med Genet 2015 Sep 28;16:87. Epub 2015 Sep 28.

"Giorgio Prodi" Cancer Research Center, University of Bologna, via Massarenti 11, 40138, Bologna, Italy.

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http://dx.doi.org/10.1186/s12881-015-0233-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587653PMC
September 2015

SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma.

J Clin Oncol 2015 Aug 11;33(24):2617-22. Epub 2015 May 11.

Edgar Ben-Josef, University of Pennsylvania, Philadelphia, PA; Katherine A. Guthrie, Fred Hutchinson Cancer Research Center, Seattle, WA; Anthony B. El-Khoueiry, University of Southern California Norris Comprehensive Cancer Center, Los Angeles; Andrew M. Lowy, University of California San Diego Moores Cancer Center, La Jolla, CA; Christopher L. Corless, Oregon Health and Science University Knight Diagnostic Laboratories; Charles R. Thomas Jr and Charles D. Blanke, Oregon Health and Science University Knight Cancer Institute, Portland, OR; Mark M. Zalupski, University of Michigan, Ann Arbor, MI; Steven R. Alberts, Mayo Clinic, Rochester, MN; Laura A. Dawson, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada; Kenneth C. Micetich, Loyola University Medical Center, Maywood, IL; Melanie B. Thomas, Medical University of South Carolina, Charleston, SC; and Abby B. Siegel, Columbia University, New York, NY.

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http://dx.doi.org/10.1200/JCO.2014.60.2219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534524PMC
August 2015

Mutation profiling in gallbladder cancer in Indian population.

Indian J Pathol Microbiol 2014 Jan-Mar;57(1):9-12

Departments of Pathology and Surgical Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, .

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http://dx.doi.org/10.4103/0377-4929.130849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472471PMC
April 2015

Hybrid Capture 2 is as effective as PCR testing for high-risk human papillomavirus in head and neck cancers.

Appl Immunohistochem Mol Morphol 2015 Apr;23(4):266-72

Departments of *Pathology ‡Otolaryngology §Dermatology Research Division †Knight Diagnostic Laboratory, Oregon Health and Science University, Portland, OR.

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http://dx.doi.org/10.1097/PDM.0000000000000036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116481PMC
April 2015

Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance.

Cancer Res 2015 Mar 28;75(5):880-91. Epub 2014 Nov 28.

Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon. Department of Cell, Developmental and Cancer Biology, Oregon Health and Science University, Portland, Oregon.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348216PMC
March 2015

Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.

J Clin Oncol 2015 Mar 9;33(9):1000-7. Epub 2015 Feb 9.

Ariel Lopez-Chavez, Anish Thomas, Arun Rajan, Mark Raffeld, Betsy Morrow, Ronan Kelly, Corey Allan Carter, Udayan Guha, Keith Killian, Christopher C. Lau, Zied Abdullaev, Liqiang Xi, Svetlana Pack, Paul S. Meltzer, David J. Liewehr, Seth M. Steinberg, Arlene Berman, Eva Szabo, Yisong Wang, and Giuseppe Giaccone, National Cancer Institute; Austin Doyle, Cancer Therapy Evaluation Program, Bethesda, MD; Ariel Lopez-Chavez, Christopher L. Corless, Alan Sandler, Carol Beadling, and Andrea Warrick, Knight Cancer Institute, Oregon Health and Science University, Portland, OR; Ariel Lopez-Chavez, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL; and Yisong Wang and Giuseppe Giaccone, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.

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http://jco.ascopubs.org/content/early/2015/02/03/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.2007
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http://dx.doi.org/10.1200/JCO.2014.58.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356709PMC
March 2015

Novel mutations in neuroendocrine carcinoma of the breast: possible therapeutic targets.

Appl Immunohistochem Mol Morphol 2015 Feb;23(2):97-103

*Department of Pathology ‡Knight Cancer Institute, Oregon Health & Science University, Portland, OR †Department of Pathology, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1097/PDM.0b013e3182a40fd1DOI Listing
February 2015

Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways.

Cancer Med 2015 Jan 28;4(1):101-3. Epub 2014 Aug 28.

Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.

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http://doi.wiley.com/10.1002/cam4.325
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http://dx.doi.org/10.1002/cam4.325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312123PMC
January 2015

Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data.

J Mol Diagn 2015 Jan 7;17(1):53-63. Epub 2014 Nov 7.

Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon; Knight Diagnostic Laboratories, Oregon Health and Science University, Portland, Oregon; Department of Pathology, Oregon Health and Science University, Portland, Oregon. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2014.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707205PMC
January 2015

Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).

BMC Cancer 2014 Sep 20;14:685. Epub 2014 Sep 20.

Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy.

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http://dx.doi.org/10.1186/1471-2407-14-685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181714PMC
September 2014

Oncogenic mutations in melanomas and benign melanocytic nevi of the female genital tract.

J Am Acad Dermatol 2014 Aug 17;71(2):229-36. Epub 2014 May 17.

Department of Dermatology, Duke University Medical Center, Durham, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2014.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450888PMC
August 2014

Frequent phosphatidylinositol-3-kinase mutations in proliferative breast lesions.

Mod Pathol 2014 May 1;27(5):740-50. Epub 2013 Nov 1.

1] Department of Pathology, Oregon Health & Science University, Portland, OR, USA [2] Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.

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http://www.nature.com/articles/modpathol2013197
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http://dx.doi.org/10.1038/modpathol.2013.197DOI Listing
May 2014

Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.

J Clin Oncol 2014 May 17;32(15):1563-70. Epub 2014 Mar 17.

Christopher L. Corless, Violetta Kolesnikova, Charles D. Blanke, Michael C. Heinrich, Oregon Health and Science University, Portland, OR; Karla V. Ballman, Mayo Clinic, Rochester, MN; Cristina R. Antonescu and Ronald P. DeMatteo, Memorial Sloan-Kettering Cancer Center; Robert G. Maki, Mt Sinai School of Medicine, New York, NY; Peter W.T. Pisters and Shreyaskumar Patel, University of Texas MD Anderson Cancer Center, Houston, TX; Martin E. Blackstein, Mount Sinai Hospital, Toronto, Ontario, Canada; George D. Demetri, Dana-Farber Cancer Institute, Boston, MA; Margaret von Mehren, Fox Chase Cancer Institute, Philadelphia, PA; Martin D. McCarter, University of Colorado School of Medicine, Aurora, CO; and Kouros Owzar, Duke University School of Medicine, Durham, NC.

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http://ascopubs.org/doi/10.1200/JCO.2013.51.2046
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http://dx.doi.org/10.1200/JCO.2013.51.2046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026579PMC
May 2014

Genetic profiling to determine risk of relapse-free survival in high-risk localized prostate cancer.

Clin Cancer Res 2014 Mar 18;20(5):1306-12. Epub 2013 Dec 18.

Authors' Affiliations: Knight Cancer Institute; Department of Public Health and Preventive Medicine; Knight Diagnostic Laboratories, Oregon Health and Science University; Portland VA Medical Center, Portland, Oregon; and Puget Sound Oncology Consortium, Seattle Cancer Care Alliance, University of Washington, Seattle, Washington.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-13-1775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947466PMC
March 2014

Expression of FAP, ADAM12, WISP1, and SOX11 is heterogeneous in aggressive fibromatosis and spatially relates to the histologic features of tumor activity.

Cancer Med 2014 Feb 26;3(1):81-90. Epub 2013 Nov 26.

Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota; Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/cam4.160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930392PMC
February 2014

Leiomyoma of the gastrointestinal tract with interstitial cells of Cajal: a mimic of gastrointestinal stromal tumor.

Am J Surg Pathol 2014 Jan;38(1):72-7

*Department of Pathology and Laboratory Medicine, Boston Medical Center ‡Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA †Department of Pathology, Oregon Health & Science University, Portland, OR.

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http://dx.doi.org/10.1097/PAS.0b013e3182a0d134DOI Listing
January 2014

Gastrointestinal stromal tumors: what do we know now?

Mod Pathol 2014 Jan;27 Suppl 1:S1-16

Department of Pathology (L471) and Knight Diagnostic Laboratories, Oregon Health and Science University, Portland, OR, USA.

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http://www.nature.com/articles/modpathol2013173
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http://dx.doi.org/10.1038/modpathol.2013.173DOI Listing
January 2014

Frequent PIK3CA mutations in radial scars.

Diagn Mol Pathol 2013 Dec;22(4):210-4

*Department of Pathology †Knight Cancer Institute, Oregon Health & Science University, Portland, OR.

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http://dx.doi.org/10.1097/PDM.0b013e318288b346DOI Listing
December 2013

Gastrointestinal stromal tumors: molecular markers and genetic subtypes.

Hematol Oncol Clin North Am 2013 Oct 26;27(5):871-88. Epub 2013 Aug 26.

Hematology and Medical Oncology, Division of Hematology/Oncology, Portland VA Medical Center, OHSU Knight Cancer Institute, Oregon Health & Science University, Mail Code L586, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.hoc.2013.07.003DOI Listing
October 2013

Gastrointestinal stromal tumour.

Lancet 2013 Sep 24;382(9896):973-83. Epub 2013 Apr 24.

Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1016/S0140-6736(13)60106-3DOI Listing
September 2013

Imatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin.

J Clin Oncol 2013 Sep 17;31(26):3182-90. Epub 2013 Jun 17.

F. Stephen Hodi, Anita Giobbie-Hurder, Philip Friedlander, Jason J. Luke, Katherine A. Zukotynski, Jeffrey T. Yap, Annick D. Van den Abbeele, and George D. Demetri, Dana-Farber Cancer Institute; Jonathan A. Fletcher, Meijun Zhu, and Adrian Marino-Enriquez, Brigham and Women's Hospital; Donald Lawrence, Keith T. Flaherty, and David E. Fisher, Massachusetts General Hospital, Boston, MA; Christopher L. Corless, Michael C. Heinrich, and Carol Beadling, Portland Veterans Administration Medical Center and Oregon Health & Science University, Portland, OR; Philip Friedlander, Mount Sinai Medical Center, New York, NY; Rene Gonzalez, University of Colorado Cancer Center, Aurora, CO; Jeffrey S. Weber, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Thomas F. Gajewski, University of Chicago, Chicago, IL; Steven J. O'Day, Beverly Hills Cancer Center, Beverly Hills, CA; Kevin B. Kim, The University of Texas MD Anderson Cancer Center, Houston, TX; Frances A. Collichio, The University of North Carolina at Chapel Hill, Chapel Hill, NC; and Marc S. Ernstoff, Geisel School of Medicine and Norris Cotton Cancer Center, Hanover, NH.

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http://dx.doi.org/10.1200/JCO.2012.47.7836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878082PMC
September 2013

PIK3CA-AKT pathway mutations in micropapillary breast carcinoma.

Hum Pathol 2013 Jul 24;44(7):1320-7. Epub 2013 Jan 24.

Department of Pathology, Oregon Health & Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.humpath.2012.10.018DOI Listing
July 2013

MDM2 Amplification and PI3KCA Mutation in a Case of Sclerosing Rhabdomyosarcoma.

Sarcoma 2013 20;2013:520858. Epub 2013 May 20.

Pediatric Cancer Biology Program, Department of Pediatrics, Papé Family Pediatric Research Institute, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Mail Code L321, Portland, OR 97239-3098, USA.

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http://dx.doi.org/10.1155/2013/520858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673319PMC
June 2013

Novel method for PIK3CA mutation analysis: locked nucleic acid--PCR sequencing.

J Mol Diagn 2013 May 27;15(3):312-8. Epub 2013 Mar 27.

Department of Pathology, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2012.12.005DOI Listing
May 2013

Combining highly multiplexed PCR with semiconductor-based sequencing for rapid cancer genotyping.

J Mol Diagn 2013 Mar 27;15(2):171-6. Epub 2012 Dec 27.

Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2012.09.003DOI Listing
March 2013

Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA.

Cancer Med 2013 Feb 3;2(1):21-31. Epub 2013 Feb 3.

Knight Cancer Institute, Oregon Health and Science University Portland, Oregon ; Division of Hematology and Oncology, Oregon Health and Science University Portland, Oregon.

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http://dx.doi.org/10.1002/cam4.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797556PMC
February 2013

Mucinous breast carcinomas lack PIK3CA and AKT1 mutations.

Hum Pathol 2012 Dec 15;43(12):2207-12. Epub 2012 Jun 15.

Department of Pathology, Oregon Health & Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.humpath.2012.03.012DOI Listing
December 2012

Biphasic papillary and lobular breast carcinoma with PIK3CA and IDH1 mutations.

Diagn Mol Pathol 2012 Dec;21(4):221-4

Department of Pathology, Oregon Health & Science University, Portland, USA.

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http://dx.doi.org/10.1097/PDM.0b013e31826ddbd1DOI Listing
December 2012

Loss of succinate dehydrogenase subunit B (SDHB) expression is limited to a distinctive subset of gastric wild-type gastrointestinal stromal tumours: a comprehensive genotype-phenotype correlation study.

Histopathology 2012 Nov 17;61(5):801-9. Epub 2012 Jul 17.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04300.xDOI Listing
November 2012

BRAF and KRAS mutations in sporadic glomus tumors.

Am J Dermatopathol 2012 Jul;34(5):533-5

Department of Pathology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1097/DAD.0b013e31823931b4DOI Listing
July 2012

Phosphatidylinositol-3-kinase pathway mutations are common in breast columnar cell lesions.

Mod Pathol 2012 Jul 30;25(7):930-7. Epub 2012 Mar 30.

Department of Pathology and Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.

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http://dx.doi.org/10.1038/modpathol.2012.55DOI Listing
July 2012

Tackling formalin-fixed, paraffin-embedded tumor tissue with next-generation sequencing.

Cancer Discov 2012 Jan;2(1):23-4

Department of Pathology, and Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0319DOI Listing
January 2012

Medicine. Personalized cancer diagnostics.

Science 2011 Dec;334(6060):1217-8

Oregon Health & Science University, Portland, OR 97201, USA.

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http://dx.doi.org/10.1126/science.1216427DOI Listing
December 2011

Novel biomarker candidates to predict hepatic fibrosis in hepatitis C identified by serum proteomics.

Dig Dis Sci 2011 Nov 17;56(11):3305-15. Epub 2011 May 17.

Department of Pediatrics, University of Minnesota, 420 Delaware St. SE, MMC 185, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s10620-011-1745-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181275PMC
November 2011

Gastrointestinal stromal tumours: origin and molecular oncology.

Nat Rev Cancer 2011 Nov 17;11(12):865-78. Epub 2011 Nov 17.

Knight Cancer Institute, Division of Haematology & Oncology, and Department of Pathology, Portland VA Medical Center and Oregon Health & Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1038/nrc3143DOI Listing
November 2011

Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification.

J Clin Oncol 2011 Jul 20;29(21):2904-9. Epub 2011 Jun 20.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital and Institute, Beijing, China.

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http://dx.doi.org/10.1200/JCO.2010.33.9275DOI Listing
July 2011

Primary melanoma of the spinal cord: a case report, molecular footprint, and review of the literature.

J Clin Oncol 2011 Jun 28;29(17):e499-502. Epub 2011 Mar 28.

Dartmouth Hitchcock Medical Center and Dartmouth Medical School, Lebanon, NH, USA.

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http://dx.doi.org/10.1200/JCO.2010.34.0695DOI Listing
June 2011

Large-scale analysis of KIT aberrations in Chinese patients with melanoma.

Clin Cancer Res 2011 Apr 15;17(7):1684-91. Epub 2011 Feb 15.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Renal Cancer and Melanoma, Peking University Cancer Hospital & Institute, Beijing, China.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-10-2346DOI Listing
April 2011

"Pediatric-type" gastrointestinal stromal tumors in adults: distinctive histology predicts genotype and clinical behavior.

Am J Surg Pathol 2011 Apr;35(4):495-504

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0b013e31820e5f7dDOI Listing
April 2011

Immunohistochemical and molecular markers in breast phyllodes tumors.

Appl Immunohistochem Mol Morphol 2011 Mar;19(2):119-25

Department of Pathology, L471, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA.

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http://dx.doi.org/10.1097/PAI.0b013e3181f5349aDOI Listing
March 2011

Hepatic and cardiac iron overload among patients with end-stage liver disease referred for liver transplantation.

Clin Transplant 2010 Sep-Oct;24(5):643-51

Division of Gastroenterology and Hepatology, Department of Medicine, Oregon Health and Science University and the Portland Veterans Affairs Medical Center, Portland, OR 97219, USA.

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http://dx.doi.org/10.1111/j.1399-0012.2009.01136.xDOI Listing
February 2011

Distinctive morphology of renal cell carcinomas in tuberous sclerosis.

Int J Surg Pathol 2010 Oct 29;18(5):409-18. Epub 2009 Apr 29.

Department of Pathology, Division of Urology & Renal Transplantation, Oregon Health & Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1177/1066896909333510DOI Listing
October 2010

Cancer: Oncogenes in context.

Nature 2010 Oct;467(7317):796-7

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http://dx.doi.org/10.1038/467796aDOI Listing
October 2010

Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation.

Am J Surg Pathol 2010 Jun;34(6):907-12

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/PAS.0b013e3181d9f18fDOI Listing
June 2010

Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma.

Breast Cancer Res Treat 2010 Apr 6;120(2):409-18. Epub 2009 May 6.

Department of Pathology, Oregon Health & Science University, L471, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA.

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http://dx.doi.org/10.1007/s10549-009-0406-1DOI Listing
April 2010

High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast.

Mod Pathol 2010 Jan 6;23(1):27-37. Epub 2009 Nov 6.

Department of Pathology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1038/modpathol.2009.142DOI Listing
January 2010

Resistance to Tyrosine Kinase Inhibitors in Gastrointestinal Stromal Tumors.

Clin Cancer Res 2009 Dec;15(24):7510-7518

Authors' Affiliations: Portland VA Medical Center and Oregon Health and Science University Knight Cancer Institute, Portland, Oregon.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-09-0190DOI Listing
December 2009

Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes.

Am J Surg Pathol 2009 Mar;33(3):437-46

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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https://insights.ovid.com/crossref?an=00000478-200903000-000
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http://dx.doi.org/10.1097/PAS.0b013e318186b158DOI Listing
March 2009

Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer.

Mol Cancer Ther 2009 Mar 10;8(3):481-9. Epub 2009 Mar 10.

University Hospital Tübingen, Department of Hematology, Oncology, Rheumatology, Immunology and Pulmonology, Otfried-Müller-Strasse 10, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-1068DOI Listing
March 2009

Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: a novel form of tumor progression.

Am J Surg Pathol 2009 Feb;33(2):218-26

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1097/PAS.0b013e31817ec2e6DOI Listing
February 2009

Imatinib targeting of KIT-mutant oncoprotein in melanoma.

Clin Cancer Res 2008 Dec;14(23):7726-32

Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1144DOI Listing
December 2008

The value of traditional upper endoscopy as a diagnostic test for Barrett's esophagus.

Gastrointest Endosc 2008 Nov 2;68(5):859-66. Epub 2008 Jun 2.

Department of Gastroenterology, Oregon Health and Science University, Portland, Oregon 97239, USA.

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http://dx.doi.org/10.1016/j.gie.2008.02.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922236PMC
November 2008

Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor.

J Clin Oncol 2008 Nov 27;26(33):5352-9. Epub 2008 Oct 27.

Division of Hematology/Oncology, Department of Medicine and Cell and Developmental Biology, Portland Veterans Affairs Medical Center and Oregon Health and Science University Cancer Institute, Portland, OR 97239, USA.

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http://dx.doi.org/10.1200/JCO.2007.15.7461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651076PMC
November 2008

KIT gene mutations and copy number in melanoma subtypes.

Clin Cancer Res 2008 Nov;14(21):6821-8

Oregon Cancer Institute, Oregon Health & Science University, Portland, Oregon 97239, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-0575DOI Listing
November 2008

Protein kinase A RII-like (R2D2) proteins exhibit differential localization and AKAP interaction.

Cell Motil Cytoskeleton 2008 Jul;65(7):539-52

VA Medical Center and Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA.

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http://dx.doi.org/10.1002/cm.20279DOI Listing
July 2008

Major response to imatinib mesylate in KIT-mutated melanoma.

J Clin Oncol 2008 Apr;26(12):2046-51

The Melanoma Program, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1200/JCO.2007.14.0707DOI Listing
April 2008