Christopher J Ricketts

Christopher J Ricketts

UNVERIFIED PROFILE

Are you Christopher J Ricketts?   Register this Author

Register author
Christopher J Ricketts

Christopher J Ricketts

Publications by authors named "Christopher J Ricketts"

Are you Christopher J Ricketts?   Register this Author

51Publications

1248Reads

49Profile Views

The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications.

Nat Rev Urol 2019 Sep 5;16(9):539-552. Epub 2019 Jul 5.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41585-019-0211-5DOI Listing
September 2019

The Metabolic Basis of Kidney Cancer.

Cancer Discov 2019 Aug 14;9(8):1006-1021. Epub 2019 May 14.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-18-1354DOI Listing
August 2019

CDC73 Germline Mutation in a Family With Mixed Epithelial and Stromal Tumors.

Urology 2019 02 16;124:91-97. Epub 2018 Nov 16.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00904295183120
Publisher Site
http://dx.doi.org/10.1016/j.urology.2018.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382532PMC
February 2019

Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma.

J Clin Oncol 2018 Oct 29:JCO2018792549. Epub 2018 Oct 29.

James J. Hsieh, Valerie H. Le, and Toshinao Oyama, Washington University, St Louis, MO; Christopher J. Ricketts, National Institutes of Health, Bethesda, MA; Thai Huu Ho, Mayo Clinic, Phoenix, AZ; and Emily H. Cheng, Memorial Sloan Kettering Cancer Center, New York, NY.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2018.79.2549
Publisher Site
http://dx.doi.org/10.1200/JCO.2018.79.2549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299341PMC
October 2018

The origin, evolution and route to metastasis of clear cell RCC.

Nat Rev Nephrol 2018 09;14(9):538-540

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41581-018-0031-5DOI Listing
September 2018

Multi-regional Sequencing Elucidates the Evolution of Clear Cell Renal Cell Carcinoma.

Cell 2018 04;173(3):540-542

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.03.077DOI Listing
April 2018

Insights into Epigenetic Remodeling in VHL-Deficient Clear Cell Renal Cell Carcinoma.

Cancer Discov 2017 11;7(11):1221-1223

Urologic Oncology Branch, Center for Cancer Research, NCI, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-17-0971DOI Listing
November 2017

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

Genes Chromosomes Cancer 2017 10 24;56(10):719-729. Epub 2017 Jul 24.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561006PMC
October 2017

Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma.

Genes Chromosomes Cancer 2017 06 31;56(6):484-492. Epub 2017 Mar 31.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.22452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637959PMC
June 2017

Kidney cancer in 2016: RCC - advances in targeted therapeutics and genomics.

Nat Rev Urol 2017 Feb 29;14(2):76-78. Epub 2016 Dec 29.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-1107, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nrurol.2016.260
Publisher Site
http://dx.doi.org/10.1038/nrurol.2016.260DOI Listing
February 2017

Targeting HIF2α in Clear-Cell Renal Cell Carcinoma.

Cancer Cell 2016 10;30(4):515-517

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-1107, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2016.09.016DOI Listing
October 2016

Gender Specific Mutation Incidence and Survival Associations in Clear Cell Renal Cell Carcinoma (CCRCC).

PLoS One 2015 20;10(10):e0140257. Epub 2015 Oct 20.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140257PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618848PMC
June 2016

Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours.

Nat Commun 2016 05 13;7:11588. Epub 2016 May 13.

Department of Molecular &Medical Genetics, Oregon Health &Science University, Mail Code: CL6S, 2730 SW Moody St, Portland, Oregon 97201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms11588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869254PMC
May 2016

Papillary Renal-Cell Carcinoma.

N Engl J Med 2016 05;374(20):1991

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1601872DOI Listing
May 2016

SnapShot: Renal Cell Carcinoma.

Cancer Cell 2016 Apr;29(4):610-610.e1

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2016.03.021DOI Listing
April 2016

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease.

Clin Cancer Res 2015 Jan;21(1):10-7

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-2993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795462PMC
January 2015

Decade in review-kidney cancer: discoveries, therapies and opportunities.

Nat Rev Urol 2014 11 7;11(11):614-6. Epub 2014 Oct 7.

Urologic Oncology Branch, National Cancer Institute, 10 Center Drive, MSC 1107, CRC Room 1W-5940, Bethesda, MD 20892-1107, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrurol.2014.262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551447PMC
November 2014

Tumor-specific hypermethylation of epigenetic biomarkers, including SFRP1, predicts for poorer survival in patients from the TCGA Kidney Renal Clear Cell Carcinoma (KIRC) project.

PLoS One 2014 15;9(1):e85621. Epub 2014 Jan 15.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085621PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893219PMC
September 2014

Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers.

Nat Rev Urol 2014 Aug 22;11(8):465-75. Epub 2014 Jul 22.

Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Building 10, CRC Room 1-5940, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrurol.2014.162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551450PMC
August 2014

Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas.

BMC Cancer 2014 Jul 10;14:506. Epub 2014 Jul 10.

Centre for Rare Diseases and Personalised Medicine and Department of Medical & Molecular Genetics, School of Clinical and Experimental Medicine, University of Birmingham College of Medical and Dental Sciences, Edgbaston, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2407-14-506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227105PMC
July 2014

The genetic basis of pheochromocytoma and paraganglioma: implications for management.

Urology 2014 Jun 15;83(6):1225-32. Epub 2014 Mar 15.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.urology.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572836PMC
June 2014

Intratumoral heterogeneity in kidney cancer.

Nat Genet 2014 Mar;46(3):214-5

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193312PMC
March 2014

Germline PTEN mutation Cowden syndrome: an underappreciated form of hereditary kidney cancer.

J Urol 2013 Dec 11;190(6):1990-8. Epub 2013 Jun 11.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.juro.2013.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193347PMC
December 2013

UBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor gene.

Hum Mutat 2013 Dec 7;34(12):1650-61. Epub 2013 Oct 7.

Centre for Rare Diseases and Personalised Medicine, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028990PMC
December 2013

New insights into von Hippel-Lindau function highlighted by investigation of the trichloroethylene-induced p.P81S hotspot mutation.

J Natl Cancer Inst 2013 Sep 29;105(18):1339-40. Epub 2013 Aug 29.

Affiliations of authors: Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD (LN, CJR, WML).

View Article

Download full-text PDF

Source
https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
Publisher Site
http://dx.doi.org/10.1093/jnci/djt240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776261PMC
September 2013

Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma.

Clin Epigenetics 2013 Sep 13;5(1):16. Epub 2013 Sep 13.

Centre for Rare Diseases and Personalised Medicine, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1868-7083-5-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848591PMC
September 2013

The metabolic basis of kidney cancer.

Semin Cancer Biol 2013 Feb 13;23(1):46-55. Epub 2012 Jun 13.

Urologic Oncology Branch, National Cancer Institute, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S1044579X120009
Publisher Site
http://dx.doi.org/10.1016/j.semcancer.2012.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563773PMC
February 2013

Adrenal nodular hyperplasia in hereditary leiomyomatosis and renal cell cancer.

J Urol 2013 Feb 19;189(2):430-5. Epub 2012 Sep 19.

Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1107, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.juro.2012.07.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435969PMC
February 2013

Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility.

Nat Genet 2012 Feb 5;44(3):277-84. Epub 2012 Feb 5.

Centre for Rare Diseases and Personalised Medicine, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.1071DOI Listing
February 2012

Mutation analysis of hypoxia-inducible factors HIF1A and HIF2A in renal cell carcinoma.

Anticancer Res 2009 Nov;29(11):4337-43

Department of Medical and Molecular Genetics, University of Birmingham, Institute of Biomedical Research, Edgbaston, Birmingham, B15 2TT, UK.

View Article

Download full-text PDF

Source
November 2009

Thiamine-responsive megaloblastic anaemia syndrome: long-term follow-up and mutation analysis of seven families.

Acta Paediatr 2006 Jan;95(1):99-104

Medical and Molecular Genetics, Medical School, University of Birmingham, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/08035250500323715DOI Listing
January 2006