Christopher J McDermott

Christopher J McDermott

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Christopher J McDermott

Publications by authors named "Christopher J McDermott"

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Exploring patient and public involvement in motor neuron disease research.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Nov 2;20(7-8):511-520. Epub 2019 Aug 2.

Sheffield Institute for Translational Neuroscience, University of Sheffield , Sheffield , United Kingdom.

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http://dx.doi.org/10.1080/21678421.2019.1643373DOI Listing
November 2019

Communication change in ALS: engaging people living with ALS and their partners in future research.

Disabil Rehabil Assist Technol 2019 Oct 4;14(7):675-681. Epub 2018 Oct 4.

d Department of Neuroscience, University of Sheffield , Sheffield , UK.

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http://dx.doi.org/10.1080/17483107.2018.1498924DOI Listing
October 2019

Clinical trials in amyotrophic lateral sclerosis.

Curr Opin Neurol 2019 Oct;32(5):758-763

Department of Neuroscience, University of Sheffield, Sheffield Institute for Translational Neuroscience, Sheffield, UK.

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http://dx.doi.org/10.1097/WCO.0000000000000731DOI Listing
October 2019

Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease.

J Neurol 2019 Oct 17. Epub 2019 Oct 17.

Sheffield Institute for Translational Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.

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http://dx.doi.org/10.1007/s00415-019-09580-xDOI Listing
October 2019

Stay at home with the amyotrophic lateral sclerosis functional rating scale.

J Neurol Neurosurg Psychiatry 2019 Sep 26. Epub 2019 Sep 26.

University of Sheffield, Sheffield S10 2RX, UK

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http://dx.doi.org/10.1136/jnnp-2019-321707DOI Listing
September 2019

Use of coping strategies in MND/ALS: Association with demographic and disease-related characteristics.

Acta Neurol Scand 2019 Aug 22;140(2):131-139. Epub 2019 May 22.

University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/ane.13113DOI Listing
August 2019

Tracheostomy in motor neurone disease.

Pract Neurol 2019 Jul 4. Epub 2019 Jul 4.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/practneurol-2018-002109DOI Listing
July 2019

Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials.

Neurology 2019 Apr 8;92(14):e1610-e1623. Epub 2019 Mar 8.

From the Department of Neurology (L.H.v.d.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Department of Neurology (E.S.), Mayo Clinic, Rochester, MN; Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City; Department of Medicine (E.A.M.), Massachusetts General Hospital, Biostatistics Center, Harvard Medical School, Boston; Department of Neurology (J.A., H.M.), Columbia University, Eleanor and Lou Gehrig ALS Center, New York, NY; Department of Neurology (R.H.B.), Cedars-Sinai Medical Center, Los Angeles, CA; Department of Neurology (M.B.), University of Miami, FL; Neurological Clinical Research Institute (J.D.B.), Massachusetts General Hospital, Boston; Rita Levi Montalcini Department of Neuroscience (A.C.), University of Torino, Italy; Centre Constitutif SLA (P.C.), Université de Tours, France; Department of Neurology (A.G.), Clinical Research Unit, Montreal Neurological Institute, Neurosurgery, McGill University, Montreal, Canada; National Institute of Neurological Disorders and Stroke (A.K.G.), National Institutes of Health, Bethesda, MD; ALS Center (C.L.-H.), University of California San Francisco; Department of Neuroscience (C.J.M.), Sheffield Institute for Translational Neuroscience, University of Sheffield, UK; Department of Neurology (E.P.P.), Section of ALS & Related Disorders, Cleveland Clinic, OH; Department of Neurology (J.R.), The Center for Restorative Neurology, Loma Linda University School of Medicine, CA; Department of Neurology and Laboratory of Neuroscience (V.S.), Istituto Auxologico Italiano, IRCCS, Milan; Department of Pathophysiology and Transplantation (V.S.), "Dino Ferrari" Centre, Università degli Studi di Milano, Milan, Italy; Nuffield Department of Clinical Neurosciences (M.R.T.), University of Oxford, UK; Neuromuscular Diseases Unit/ALS Clinic (M.W.), Kantonsspital St. Gallen, Switzerland; Carolinas Neuromuscular/ALS-MDA Care Center (B.R.B.), Charlotte; Department of Neurology (B.R.B.), Carolinas Medical Center, University of North Carolina School of Medicine, Charlotte; Forbes Norris ALS Treatment and Research Center (R.G.M.), California Pacific Medical Center San Francisco; and Department of Neurosciences (R.G.M.), Stanford University, CA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000007242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448453PMC
April 2019

Novel genotype-phenotype and MRI correlations in a large cohort of patients with mutations.

Neurol Genet 2018 Dec 24;4(6):e279. Epub 2018 Oct 24.

Academic Directorate of Neurosciences (C.A.A.H., R.O'.M., M.K.R., S.P., Z.P., S.B., C.J.M., P.J.S., M.H.), Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital; Sheffield Institute for Translational Neuroscience (SITraN) (C.A.A.H., R.S., T.R., C.J.M., P.J.S., M.H.), University of Sheffield; Sheffield Diagnostic Genetics Service (N.J.B., J.M.), Sheffield Children's NHS Foundation Trust; Department of Clinical Neurophysiology (G.R., P.S.), Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital; Academic Unit of Radiology (N.H.), University of Sheffield, Royal Hallamshire Hospital; and Sheffield NIHR Biomedical Research Centre for Translational Neuroscience (C.A.A.H., N.H., R.S., P.S., S.B., C.J.M., P.J.S., M.H.), United Kingdom.

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http://dx.doi.org/10.1212/NXG.0000000000000279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244025PMC
December 2018

The TiM system: developing a novel telehealth service to improve access to specialist care in motor neurone disease using user-centered design.

Amyotroph Lateral Scler Frontotemporal Degener 2018 08 16;19(5-6):351-361. Epub 2018 Feb 16.

a Sheffield Institute for Translational Neuroscience , University of Sheffield (SITraN) , Sheffield , UK.

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http://dx.doi.org/10.1080/21678421.2018.1440408DOI Listing
August 2018

Efficacy of the Head Up collar in facilitating functional head movements in patients with Amyotrophic Lateral Sclerosis.

Clin Biomech (Bristol, Avon) 2018 08 25;57:114-120. Epub 2018 Jun 25.

NIHR Devices for Dignity MedTech Healthcare Technology Co-operative, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1016/j.clinbiomech.2018.06.016DOI Listing
August 2018

A comfort assessment of existing cervical orthoses.

Ergonomics 2018 Feb 28;61(2):329-338. Epub 2017 Jul 28.

i Sheffield Institute for Translational Neuroscience, University of Sheffield , Sheffield , UK.

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http://dx.doi.org/10.1080/00140139.2017.1353137DOI Listing
February 2018

Targeted Genetic Screen in Amyotrophic Lateral Sclerosis Reveals Novel Genetic Variants with Synergistic Effect on Clinical Phenotype.

Front Mol Neurosci 2017 9;10:370. Epub 2017 Nov 9.

Maurice Wohl Clinical Neuroscience Institute, King's College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; Maurice Wohl Clinical Neuroscience Institute, King's College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; Suna and Inan Kirac Foundation, Neurodegeneration Research Laboratory, Bogazici University, Istanbul, Turkey; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Academic Unit of Neurology, Trinity College Dublin, Trinity Biomedical Sciences Institute, Dublin, Republic of Ireland; Department of Neurology, Beaumont Hospital, Dublin, Republic of Ireland; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom; Biostatistics Department, Harvard School of Public Health, Boston, MA, United States; Department of Biostatistics, IoPPN, King's College London, London, United Kingdom; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, United States; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, United States; Population Genetics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Republic of Ireland; Maurice Wohl Clinical Neuroscience Institute, King's College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; University of Exeter Medical School, Exeter University, St. Luke's Campus, Magdalen Street, Exeter EX1 2LU, United Kingdom; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), B-3000 Leuven, Belgium; VIB, Vesalius Research Center, Laboratory of Neurobiology, Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Leuven, Belgium; Hospital San Rafael, Madrid, Spain; Faculty of Medicine, University of Southampton, Southampton, United Kingdom; Department of Biostatistics, IoPPN, King's College London, London, United Kingdom; Biomedical Research Centre for Mental Health, IoPPN, King's College London, London, United Kingdom; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Maurice Wohl Clinical Neuroscience Institute, King's College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; Maurice Wohl Clinical Neuroscience Institute, King's College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; Maurice Wohl Clinical Neuroscience Institute, King's College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), B-3000 Leuven, Belgium, VIB, Vesalius Research Center, Laboratory of Neurobiology, Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Leuven, Belgium; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands; SURFsara, Amsterdam, Netherlands; Emory University, Atlanta, United States; KU Leuven - University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), B-3000 Leuven, Belgium; VIB, Vesalius Research Center, Laboratory of Neurobiology, Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Leuven, Belgium; Hadassah University Hospital, Jerusalem, Israel; Tel-Aviv Medical Center, Tel-Aviv, Israel; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia; Universidade de São Paulo, Brazil; Universidade de São Paulo, Brazil; Université de Limoges, France; Université François-Rabelais, Tours, France; IRCCS Instituto Auxologico Italiano, Milan, Italy; Universita degli Studi dei Torino, Turin, Italy; Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal; Instituto de Medicina Molecular, University of Lisbon, Lisbon, Portugal; Hospital Carlos III, Madrid, Spain; Umeå University, Umeå, Sweden; Kantonspittal St. Gallen, St. Gallen, Switzerland; IRCCS Instituto Auxologico Italiano, Milan, Italy.

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http://dx.doi.org/10.3389/fnmol.2017.00370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684183PMC
November 2017

Evaluating a novel cervical orthosis, the Sheffield Support Snood, in patients with amyotrophic lateral sclerosis/motor neuron disease with neck weakness.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):436-42. Epub 2016 Feb 26.

f Sheffield Institute for Translational Neuroscience, University of Sheffield , Sheffield , and.

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http://dx.doi.org/10.3109/21678421.2016.1148170DOI Listing
October 2017

Long-term physical activity: an exogenous risk factor for sporadic amyotrophic lateral sclerosis?

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):377-84. Epub 2016 Mar 21.

a Academic Neurology Unit, Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, Faculty of Medicine, Dentistry and Health , University of Sheffield , 385A Glossop Road , Sheffield , S10 2HQ , UK and.

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http://dx.doi.org/10.3109/21678421.2016.1154575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950417PMC
October 2017

Using technology to improve access to specialist care in amyotrophic lateral sclerosis: A systematic review.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):313-24. Epub 2016 Mar 30.

a Sheffield Institute for Translational Neuroscience, University of Sheffield (SITraN) , Sheffield , UK .

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http://dx.doi.org/10.3109/21678421.2016.1165255DOI Listing
October 2017

A mapping review of international guidance on the management and care of amyotrophic lateral sclerosis (ALS).

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):325-36. Epub 2016 Apr 14.

m Walter Sermeus, KU Leuven Institute for Healthcare Policy, Department of Public Health and Primary Care , University of Leuven - KU Leuven , Leuven , Belgium.

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http://dx.doi.org/10.3109/21678421.2016.1167911DOI Listing
October 2017

Withdrawal of tracheostomy ventilation in motor neurone disease: implementing advance directives.

Pract Neurol 2017 10 17;17(5):339-340. Epub 2017 Jul 17.

LOROS Hospice and University Hospitals of Leicester, Leicester, UK.

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http://dx.doi.org/10.1136/practneurol-2017-001694DOI Listing
October 2017

"Anything that makes life's journey better." Exploring the use of digital technology by people living with motor neurone disease.

Amyotroph Lateral Scler Frontotemporal Degener 2017 08 20;18(5-6):378-387. Epub 2017 Feb 20.

a Sheffield Institute for Translational Neurosciences, University of Sheffield , Sheffield , UK and.

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http://dx.doi.org/10.1080/21678421.2017.1288253DOI Listing
August 2017

Decision-making and referral processes for patients with motor neurone disease: a qualitative study of GP experiences and evaluation of a new decision-support tool.

BMC Health Serv Res 2017 05 8;17(1):339. Epub 2017 May 8.

Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1186/s12913-017-2286-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422976PMC
May 2017

Management of oral secretions in neurological disease.

Pract Neurol 2017 Apr 10;17(2):96-103. Epub 2017 Feb 10.

Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK

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http://dx.doi.org/10.1136/practneurol-2016-001515DOI Listing
April 2017

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2017 02 31;18(1-2):1-9. Epub 2016 Aug 31.

a Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, & Academic Directorate of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield.

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http://dx.doi.org/10.1080/21678421.2016.1221433DOI Listing
February 2017

Enteral feeding in neurological disorders.

Pract Neurol 2016 Oct 5;16(5):352-61. Epub 2016 May 5.

Department of Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), The University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1136/practneurol-2016-001408DOI Listing
October 2016

The role of cranial and thoracic electromyography within diagnostic criteria for amyotrophic lateral sclerosis.

Muscle Nerve 2016 09 9;54(3):378-85. Epub 2016 Jun 9.

Sheffield Institute for Translational Neuroscience, University of Sheffield, 385A Glossop Road, Sheffield, S10 2HQ, UK.

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http://dx.doi.org/10.1002/mus.25062DOI Listing
September 2016

Supportive and symptomatic management of amyotrophic lateral sclerosis.

Nat Rev Neurol 2016 09 12;12(9):526-38. Epub 2016 Aug 12.

Sheffield Institute for Translational Neuroscience, University of Sheffield, 385a Glossop Rd, Sheffield, S10 2HQ, UK.

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http://dx.doi.org/10.1038/nrneurol.2016.111DOI Listing
September 2016

A preliminary randomized trial of the mechanical insufflator-exsufflator versus breath-stacking technique in patients with amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2015 3;16(7-8):448-55. Epub 2015 Jul 3.

a Academic Neurology Unit, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield , Sheffield , UK.

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http://dx.doi.org/10.3109/21678421.2015.1051992DOI Listing
August 2016

Effect of lipid profile on prognosis in the patients with amyotrophic lateral sclerosis: Insights from the olesoxime clinical trial.

Amyotroph Lateral Scler Frontotemporal Degener 2015 10;16(7-8):478-84. Epub 2015 Jul 10.

a The Academic Neurology Unit, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield , Sheffield , UK.

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http://dx.doi.org/10.3109/21678421.2015.1062517DOI Listing
August 2016

Rueing the Roux-en-Y.

Pract Neurol 2016 Jun 9;16(3):227-30. Epub 2015 Dec 9.

Sheffield Institute for Translational Neuroscience, Sheffield, UK Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK.

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http://dx.doi.org/10.1136/practneurol-2015-001327DOI Listing
June 2016

Diaphragm pacing in patients with amyotrophic lateral sclerosis - Authors' reply.

Lancet Neurol 2016 05 11;15(6):543-4. Epub 2016 Apr 11.

University of Sheffield, Sheffield, S10 2HQ, UK.

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http://dx.doi.org/10.1016/S1474-4422(16)30010-2DOI Listing
May 2016

Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS.

Neuropathology 2016 Apr 24;36(2):125-34. Epub 2015 Aug 24.

Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1111/neup.12240DOI Listing
April 2016

The impact of gastrostomy in motor neurone disease: challenges and benefits from a patient and carer perspective.

BMJ Support Palliat Care 2016 Mar 21;6(1):52-9. Epub 2014 May 21.

Academic Neurology Unit, Department of Neuroscience, Sheffield Institute for Translational Neuroscience (SITraN), The University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1136/bmjspcare-2013-000609DOI Listing
March 2016

Assessment of the Sheffield Support Snood, an innovative cervical orthosis designed for people affected by neck muscle weakness.

Clin Biomech (Bristol, Avon) 2016 Feb 2;32:201-6. Epub 2015 Dec 2.

Department of Mechanical Engineering, University of Sheffield, Sheffield, UK; Insigneo Institute for In silico Medicine, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1016/j.clinbiomech.2015.11.010DOI Listing
February 2016

Gastrostomy in amyotrophic lateral sclerosis: effects of non-invasive ventilation - Authors' reply.

Lancet Neurol 2015 Dec;14(12):1153

Sheffield Institute for Translational Neuroscience, University of Sheffield, 385A Glossop Road, Sheffield, S10 2HQ, Sheffield, UK.

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http://dx.doi.org/10.1016/S1474-4422(15)00294-XDOI Listing
December 2015

Developing an outcome measure for excessive saliva management in MND and an evaluation of saliva burden in Sheffield.

Amyotroph Lateral Scler Frontotemporal Degener 2015 Mar 16;16(1-2):108-13. Epub 2014 Sep 16.

Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, & Directorate of Neuroscience, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield , UK.

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http://dx.doi.org/10.3109/21678421.2014.951942DOI Listing
March 2015

The evidence for symptomatic treatments in amyotrophic lateral sclerosis.

Curr Opin Neurol 2014 Oct;27(5):524-31

Sheffield Institute for Translational Neuroscience, Sheffield, UK.

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http://dx.doi.org/10.1097/WCO.0000000000000135DOI Listing
October 2014

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.

Acta Neuropathol 2014 Mar 19;127(3):407-18. Epub 2014 Jan 19.

Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s00401-013-1239-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003885PMC
March 2014

Factors influencing decision-making in relation to timing of gastrostomy insertion in patients with motor neurone disease.

BMJ Support Palliat Care 2014 Mar 11;4(1):57-63. Epub 2013 Dec 11.

Sheffield Institute for Translational Neuroscience (SITraN), The University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1136/bmjspcare-2013-000497DOI Listing
March 2014

Management of sialorrhoea in motor neuron disease: a survey of current UK practice.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Dec 7;14(7-8):521-7. Epub 2013 May 7.

Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, & Academic Directorate of Neurosciences, Royal Hallamshire Hospital , Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield.

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http://dx.doi.org/10.3109/21678421.2013.790452DOI Listing
December 2013

Use of non-invasive ventilation at end of life.

Palliat Med 2013 Oct;27(9):878

School of Health and Related Research, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.1177/0269216313495098DOI Listing
October 2013

A prospective pilot study measuring muscle volumetric change in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Sep 27;14(5-6):414-23. Epub 2013 May 27.

Sheffield Institute for Translational Neuroscience (SITraN), 385a Glossop Road, Sheffield, UK.

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http://dx.doi.org/10.3109/21678421.2013.795597DOI Listing
September 2013

Gastrostomy use in motor neurone disease (MND): a review, meta-analysis and survey of current practice.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Mar 17;14(2):96-104. Epub 2012 Sep 17.

Academic Neurology Unit, Department of Neuroscience, Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK.

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http://dx.doi.org/10.3109/17482968.2012.723722DOI Listing
March 2013

The natural history of motor neuron disease: assessing the impact of specialist care.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Jan 29;14(1):13-9. Epub 2012 May 29.

Academic Neurology Unit, Sheffield Institute for Translational Neuroscience, University of Sheffield, South Yorkshire, UK.

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http://dx.doi.org/10.3109/17482968.2012.690419DOI Listing
January 2013

Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72.

J Neurol Neurosurg Psychiatry 2013 Jan 20;84(1):79-87. Epub 2012 Oct 20.

Academic Neurology Unit, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385A Glossop Road, Sheffield S10 2HQ, UK.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2012-303326
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http://dx.doi.org/10.1136/jnnp-2012-303326DOI Listing
January 2013

Chapter 17 Hereditary spastic paraparesis.

Handb Clin Neurol 2007 ;82:327-52

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http://dx.doi.org/10.1016/S0072-9752(07)80020-0DOI Listing
October 2012

Using transcutaneous carbon dioxide monitor (TOSCA 500) to detect respiratory failure in patients with amyotrophic lateral sclerosis: a validation study.

Amyotroph Lateral Scler 2012 Oct 7;13(6):528-32. Epub 2012 Aug 7.

Academic Neurology Unit, Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, South Yorkshire, UK. m.k.rafi q@sheffi eld.ac.uk

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http://dx.doi.org/10.3109/17482968.2012.688836DOI Listing
October 2012

Respiratory management of motor neurone disease: a review of current practice and new developments.

Pract Neurol 2012 Jun;12(3):166-76

Academic Neurology Unit, Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, UK. m.k.rafi q@sheffi eld.ac.uk

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http://dx.doi.org/10.1136/practneurol-2011-000199DOI Listing
June 2012

Non-invasive ventilation in motor neuron disease: an update of current UK practice.

J Neurol Neurosurg Psychiatry 2012 Apr 17;83(4):371-6. Epub 2011 Aug 17.

Department of Palliative Medicine, St Oswald’s Hospice, Newcastle-upon-Tyne, UK.

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http://jnnp.bmj.com/content/83/4/371.full.pdf
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http://jnnp.bmj.com/cgi/doi/10.1136/jnnp-2011-300480
Publisher Site
http://dx.doi.org/10.1136/jnnp-2011-300480DOI Listing
April 2012

The changing landscape of non-invasive ventilation in amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2012 Apr;83(4):368-9

Department of Respiratory Medicine, North Tyneside General Hospital, Tyne and Wear, UK.

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http://dx.doi.org/10.1136/jnnp-2012-302253DOI Listing
April 2012

Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis.

Neurogenetics 2010 May 17;11(2):217-25. Epub 2009 Sep 17.

Department of Neuroscience, Faculty of Medicine, Dentistry and Health, University of Sheffield, Medical School, Sheffield, UK.

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http://dx.doi.org/10.1007/s10048-009-0218-9DOI Listing
May 2010

Novel FUS/TLS mutations and pathology in familial and sporadic amyotrophic lateral sclerosis.

Arch Neurol 2010 Apr;67(4):455-61

Academic Unit of Neurology, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, England.

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http://dx.doi.org/10.1001/archneurol.2010.52DOI Listing
April 2010

Physical activity as an exogenous risk factor in motor neuron disease (MND): a review of the evidence.

Amyotroph Lateral Scler 2009 Aug;10(4):191-204

Academic Neurology Unit, Section of Neuroscience, School of Medicine and Biomedical Sciences, University of Sheffield, UK.

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http://dx.doi.org/10.1080/17482960802549739DOI Listing
August 2009

Diagnosis and management of motor neurone disease.

BMJ 2008 Mar;336(7645):658-62

Sheffield Care and Research Centre for Motor Neurone Disorders/Academic Neurology Unit, Section of Neuroscience, University of Sheffield, Sheffield S10 2RX.

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http://dx.doi.org/10.1136/bmj.39493.511759.BEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270983PMC
March 2008

The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo.

Hum Mol Genet 2006 Sep 7;15(18):2763-71. Epub 2006 Aug 7.

MRC Centre Development for Developmental and Biomedical Genetics, Department of Biomedical Science, University of Sheffield, UK.

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http://dx.doi.org/10.1093/hmg/ddl212DOI Listing
September 2006

Hereditary spastic paraparesis: disrupted intracellular transport associated with spastin mutation.

Ann Neurol 2003 Dec;54(6):748-59

Academic Neurology Unit, University of Sheffield, Beech Hill Road, Sheffield S10 2RX, United Kingdom.

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http://dx.doi.org/10.1002/ana.10757DOI Listing
December 2003

Spastin and paraplegin gene analysis in selected cases of motor neurone disease (MND).

Amyotroph Lateral Scler Other Motor Neuron Disord 2003 Jun;4(2):96-9

Academic Neurology Unit, University of Sheffield, E Floor, Medical School, Beech Hill Rd, Sheffield S10 2RX, UK.

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June 2003

Hereditary spastic paraplegia.

Int Rev Neurobiol 2002 ;53:191-204

Academic Neurology Unit, University of Sheffield Medical School, Royal Hallamshire Hospital, Sheffield S10 2RX, United Kingdom.

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March 2003