Christopher J Carroll

Christopher J Carroll

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Christopher J Carroll

Christopher J Carroll

Publications by authors named "Christopher J Carroll"

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Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions.

Cell Metab 2019 Dec 12;30(6):1040-1054.e7. Epub 2019 Sep 12.

Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland; Department of Neurosciences, Helsinki University Central Hospital, 00290 Helsinki, Finland; Neuroscience Center, University of Helsinki, 00290 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.08.019DOI Listing
December 2019

A urinary biosignature for mitochondrial myopathy, encephalopathy, lactic acidosis and stroke like episodes (MELAS).

Mitochondrion 2019 03 19;45:38-45. Epub 2018 Feb 19.

Mitochondria Research Laboratory, Centre for Human Metabolomics, North-West University, Potchefstroom, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2018.02.003DOI Listing
March 2019

Genetic Basis of Severe Childhood-Onset Cardiomyopathies.

J Am Coll Cardiol 2018 11;72(19):2324-2338

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki, Finland; Department of Neurology, Helsinki University Hospital and Clinical Neurosciences, University of Helsinki, Helsinki, Finland; Neuroscience Center, HiLife, University of Helsinki, Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.08.2171DOI Listing
November 2018

Reply to 'Letter to Editor by Finsterer J and Zarrouk-Mahjoub S: Phenotypic manifestations of the m.8969G>A variant'.

Neurogenetics 2018 05 26;19(2):133-134. Epub 2018 Feb 26.

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1007/s10048-018-0542-zDOI Listing
May 2018

Defective mitochondrial ATPase due to rare mtDNA m.8969G>A mutation-causing lactic acidosis, intellectual disability, and poor growth.

Neurogenetics 2018 01 19;19(1):49-53. Epub 2018 Jan 19.

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1007/s10048-018-0537-9DOI Listing
January 2018

Defective mitochondrial RNA processing due to PNPT1 variants causes Leigh syndrome.

Hum Mol Genet 2017 09;26(17):3352-3361

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki 00290, Finland.

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http://dx.doi.org/10.1093/hmg/ddx221DOI Listing
September 2017

Absence of Hikeshi, a nuclear transporter for heat-shock protein HSP70, causes infantile hypomyelinating leukoencephalopathy.

Eur J Hum Genet 2017 02 21;25(3):366-370. Epub 2016 Dec 21.

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/ejhg.2016.189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315520PMC
February 2017

Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.

Cell Metab 2016 Apr 25;23(4):635-48. Epub 2016 Feb 25.

Research Programs Unit, Molecular Neurology, University of Helsinki, 00290 Helsinki, Finland; Department of Neurology, University of Helsinki, Helsinki University Hospital, 00290 Helsinki, Finland; Neuroscience Center, University of Helsinki, 00790 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.01.019DOI Listing
April 2016

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3.

EMBO Mol Med 2014 Jun;6(6):721-31

Molecular Neurology, Research Programs Unit, University of Helsinki, Helsinki, Finland Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland Neuroscience Research Centre University of Helsinki, Helsinki, Finland

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http://dx.doi.org/10.1002/emmm.201403943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203351PMC
June 2014

Regulation of myocardial interleukin-6 expression by p53 and STAT1.

J Interferon Cytokine Res 2013 Sep 15;33(9):542-8. Epub 2013 May 15.

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1089/jir.2012.0165DOI Listing
September 2013

Whole-exome sequencing identifies a mutation in the mitochondrial ribosome protein MRPL44 to underlie mitochondrial infantile cardiomyopathy.

J Med Genet 2013 Mar 12;50(3):151-9. Epub 2013 Jan 12.

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, r.C523B, Haartmaninkatu 8, Helsinki 00290, Finland.

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http://dx.doi.org/10.1136/jmedgenet-2012-101375DOI Listing
March 2013

Mitochondrial phenylalanyl-tRNA synthetase mutations underlie fatal infantile Alpers encephalopathy.

Hum Mol Genet 2012 Oct 23;21(20):4521-9. Epub 2012 Jul 23.

Research Programs Unit, Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, 00290 Helsinki, Finland.

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http://dx.doi.org/10.1093/hmg/dds294DOI Listing
October 2012

Transgenic overexpression of HSP56 does not result in cardiac hypertrophy nor protect from ischaemia/reperfusion injury.

Int J Biochem Cell Biol 2011 Jan 29;43(1):74-9. Epub 2010 Oct 29.

Medical Molecular Biology Unit, Institute of Child Health, University College London, London WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.biocel.2010.09.020DOI Listing
January 2011

Mitochondrial myopathy induces a starvation-like response.

Hum Mol Genet 2010 Oct 23;19(20):3948-58. Epub 2010 Jul 23.

Research Program of Molecular Neurology, Biomedicum-Helsinki, 00290 Helsinki, Finland.

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http://dx.doi.org/10.1093/hmg/ddq310DOI Listing
October 2010

Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways.

J Immunol 2010 Jun 17;184(12):6622-8. Epub 2010 May 17.

Medical Molecular Biology Unit, Institute of Child Health, Department of Medicine, Centre for Rheumatology Research, University College London, London, UK.

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http://dx.doi.org/10.4049/jimmunol.0902765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898497PMC
June 2010

Ketogenic diet slows down mitochondrial myopathy progression in mice.

Hum Mol Genet 2010 May 17;19(10):1974-84. Epub 2010 Feb 17.

Research Program of Molecular Neurology, Biomedicum-Helsinki, University of Helsinki, Helsinki 00290, Finland.

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http://dx.doi.org/10.1093/hmg/ddq076DOI Listing
May 2010

Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury.

J Mol Cell Cardiol 2006 Jun 12;40(6):846-52. Epub 2006 May 12.

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.yjmcc.2006.03.428DOI Listing
June 2006

The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage.

Biochem Biophys Res Commun 2004 Aug;321(2):479-86

Medical Molecular Biology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.bbrc.2004.06.170DOI Listing
August 2004

YAC transgenic mice carrying pathological alleles of the MJD1 locus exhibit a mild and slowly progressive cerebellar deficit.

Hum Mol Genet 2002 May;11(9):1075-94

Cell and Molecular Biology, Leukocyte Biology, Division of Biomedical Sciences, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College, London SW7 2AZ, UK.

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http://dx.doi.org/10.1093/hmg/11.9.1075DOI Listing
May 2002