Christopher G Mueller

Vitamin D3-elicited CD14+ human skin dendritic cells promote thymic stromal lymphopoietin-independent type 2 T-helper responses.

Authors:

Adrien Brulefert Astrid Hoste Quentin Muller Jean-Daniel Fauny Christopher G Mueller Vincent Flacher

Allergy 2020 Dec 23. Epub 2020 Dec 23.

Laboratory CNRS UPR3572 Immunology, Immunopathology and Therapeutic Chemistry (I2CT) / LabEx Medalis, Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, Strasbourg, France.

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December 2020

[The sinusoidal microenvironment regulates the niche and the differentiation of lymph node macrophages].

Authors:

Christopher G Mueller Abdouramane Camara Vincent Flacher

Med Sci (Paris) 2020 Oct 7;36(10):835-838. Epub 2020 Oct 7.

CNRS UPR 3572, Université de Strasbourg, IBMC, 2 allée Konrad Roentgen, 67000 Strasbourg, France.

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October 2020

Tenascin-C Orchestrates an Immune-Suppressive Tumor Microenvironment in Oral Squamous Cell Carcinoma.

Cancer Immunol Res 2020 Sep 14;8(9):1122-1138. Epub 2020 Jul 14.

Université Strasbourg, INSERM U1109-MN3T, The Microenvironmental Niche in Tumorigenesis and Targeted Therapy, and The Tumor Microenvironment Laboratory, Hopital Civil, Institut d'Hématologie et d'Immunologie, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France.

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September 2020

Genetically-achieved disturbances to the expression levels of TNFSF11 receptors modulate the effects of zoledronic acid on growing mouse skeletons.

Authors:

Jorge William Vargas-Franco Beatriz Castaneda Andrea Gama Christopher G Mueller Dominique Heymann Françoise Rédini Frédéric Lézot

Biochem Pharmacol 2019 10 28;168:133-148. Epub 2019 Jun 28.

INSERM, UMR-1238, Equipe 1, Faculté de Médecine, Université de Nantes, Nantes F-44035, France. Electronic address:

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October 2019

Lymph Node Mesenchymal and Endothelial Stromal Cells Cooperate via the RANK-RANKL Cytokine Axis to Shape the Sinusoidal Macrophage Niche.

Authors:

Abdouramane Camara Olga G Cordeiro Farouk Alloush Janina Sponsel Mélanie Chypre Lucas Onder Kenichi Asano Masato Tanaka Hideo Yagita Burkhard Ludewig Vincent Flacher Christopher G Mueller

Immunity 2019 06 11;50(6):1467-1481.e6. Epub 2019 Jun 11.

CNRS UPR 3572, IBMC, University of Strasbourg, 67000 Strasbourg, France. Electronic address:

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June 2019

sp-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo.

Authors:

Evelyne Schaeffer Elena M Sánchez-Fernández Rita Gonçalves-Pereira Vincent Flacher Delphine Lamon Monique Duval Jean-Daniel Fauny José M García Fernández Christopher G Mueller Carmen Ortiz Mellet

Eur J Med Chem 2019 May 5;169:111-120. Epub 2019 Mar 5.

Department of Organic Chemistry, Faculty of Chemistry, University of Seville, c/ Profesor García González 1, 41012, Seville, Spain. Electronic address:

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May 2019

Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups.

Authors:

Benjamin Navet Jorge William Vargas-Franco Andrea Gama Jérome Amiaud Yongwon Choi Hideo Yagita Christopher G Mueller Françoise Rédini Dominique Heymann Beatriz Castaneda Frédéric Lézot

J Clin Med 2018 Nov 8;7(11). Epub 2018 Nov 8.

INSERM, UMR 1238, Faculté de Médecine, Université de Nantes, F-44035 Nantes, France.

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November 2018

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases.

Authors:

Benjamin Navet Kosei Ando Jorge William Vargas-Franco Régis Brion Jérome Amiaud Kanji Mori Hideo Yagita Christopher G Mueller Franck Verrecchia Clotilde Dumars Marie-Françoise Heymann Dominique Heymann Frédéric Lézot

Cancers (Basel) 2018 Oct 24;10(11). Epub 2018 Oct 24.

INSERM, UMR 1238, Faculté de Médecine, Université de Nantes, F-44035 Nantes, France.

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October 2018

Mannoside Glycolipid Conjugates Display Antiviral Activity Against Ebola Virus.

Authors:

Olivier Reynard Evelyne Schaeffer Valentina A Volchkova Andrea Cimarelli Christopher G Mueller Viktor E Volchkov

J Infect Dis 2018 11;218(suppl_5):S666-S671

Laboratory Molecular Basis of Viral Pathogenicity, Centre International de Recherche en Infectiologie, INSERM, University of Lyon, Université Claude Bernard Lyon, ENS de Lyon, CNRS, UMR, Lyon, France.

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November 2018

Inhibition of dengue virus infection by mannoside glycolipid conjugates.

Authors:

Evelyne Schaeffer Vincent Flacher Patrick Neuberg Astrid Hoste Adrien Brulefert Jean-Daniel Fauny Alain Wagner Christopher G Mueller

Antiviral Res 2018 06 6;154:116-123. Epub 2018 Apr 6.

CNRS, Université de Strasbourg, Immunopathology and Therapeutic Chemistry, UPR 3572, 67000 Strasbourg, France. Electronic address:

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June 2018

Porphyrin Derivatives Inhibit the Interaction between Receptor Activator of NF-κB and Its Ligand.

Authors:

Mélanie Chypre Maria-Bernadette Madel Olivier Chaloin Claudine Blin-Wakkach Christophe Morice Christopher G Mueller

ChemMedChem 2017 10 4;12(20):1697-1702. Epub 2017 Oct 4.

Université de Strasbourg, CNRS UPR 3572, Immunopathology and Therapeutic Chemistry, 67000, Strasbourg, France.

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October 2017

Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.

Authors:

Lucas Onder Urs Mörbe Natalia Pikor Mario Novkovic Hung-Wei Cheng Thomas Hehlgans Klaus Pfeffer Burkhard Becher Ari Waisman Thomas Rülicke Jennifer Gommerman Christopher G Mueller Shinichiro Sawa Elke Scandella Burkhard Ludewig

Immunity 2017 07 11;47(1):80-92.e4. Epub 2017 Jul 11.

Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland. Electronic address:

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July 2017

RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model.

Authors:

Bouchra Sojod Danielle Chateau Christopher G Mueller Sylvie Babajko Ariane Berdal Frédéric Lézot Beatriz Castaneda

Front Physiol 2017 24;8:338. Epub 2017 May 24.

INSERM, UMR-1138, Laboratoire de Physiopathologie Orale Moléculaire, Centre de Recherche des CordeliersParis, France.

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May 2017

Of skin and bone: did Langerhans cells and osteoclasts evolve from a common ancestor?

Authors:

Christopher G Mueller Benjamin Voisin

J Anat 2019 08 13;235(2):412-417. Epub 2016 Sep 13.

CNRS UPR 3572, Laboratory of Immunopathology and Therapeutic Chemistry/Laboratory of Excellence MEDALIS, Institut de Biologie Moléculaire et Cellulaire, University of Strasbourg, 67000 Strasbourg, France.

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August 2019

Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL.

Authors:

Olga G Cordeiro Mélanie Chypre Nathalie Brouard Simon Rauber Farouk Alloush Monica Romera-Hernandez Cécile Bénézech Zhi Li Anita Eckly Mark C Coles Antal Rot Hideo Yagita Catherine Léon Burkhard Ludewig Tom Cupedo François Lanza Christopher G Mueller

PLoS One 2016 24;11(3):e0151848. Epub 2016 Mar 24.

CNRS UPR 3572, University of Strasbourg, Laboratory of Immunopathology and Therapeutic Chemistry/ MEDALIS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France.

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August 2016

Characterization and application of two RANK-specific antibodies with different biological activities.

Authors:

Mélanie Chypre Jonathan Seaman Olga G Cordeiro Laure Willen Kathryn A Knoop Andrew Buchanan Richard C A Sainson Ifor R Williams Hideo Yagita Pascal Schneider Christopher G Mueller

Immunol Lett 2016 Mar 7;171:5-14. Epub 2016 Jan 7.

CNRS UPR 3572, Laboratory of Immunopathology and Therapeutic Chemistry, University of Strasbourg, Strasbourg 67000, France. Electronic address:

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March 2016

Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.

Authors:

Vincent Flacher Patrick Neuberg Floriane Point François Daubeuf Quentin Muller David Sigwalt Jean-Daniel Fauny Jean-Serge Remy Nelly Frossard Alain Wagner Christopher G Mueller Evelyne Schaeffer

ACS Chem Biol 2015 Dec 30;10(12):2697-705. Epub 2015 Sep 30.

Laboratory of Immunopathology and Therapeutic Chemistry, CNRS UPR 3572/Laboratory of Excellence MEDALIS, Institut de Biologie Moléculaire et Cellulaire , 15 rue René Descartes, 67000 Strasbourg, France.

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December 2015

Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: mouse strain disparities and synergic effect with zoledronic acid.

Authors:

Frédéric Lézot Julie Chesneau Benjamin Navet Bérengère Gobin Jérome Amiaud YongWon Choi Hideo Yagita Beatriz Castaneda Ariane Berdal Christopher G Mueller Françoise Rédini Dominique Heymann

Bone 2015 Apr 20;73:51-9. Epub 2014 Dec 20.

INSERM, UMR-957, Equipe Ligue Nationale Contre le Cancer 2012, Nantes F-44035, France; Université de Nantes, Faculté de Médecine, Laboratoire de physiopathologie de la résorption osseuse et thérapie des tumeurs osseuses primitives, Nantes F-44035, France.

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April 2015

Dermal CD14(+) Dendritic Cell and Macrophage Infection by Dengue Virus Is Stimulated by Interleukin-4.

Authors:

Evelyne Schaeffer Vincent Flacher Vasiliki Papageorgiou Marion Decossas Jean-Daniel Fauny Melanie Krämer Christopher G Mueller

J Invest Dermatol 2015 Jul 18;135(7):1743-1751. Epub 2014 Dec 18.

Laboratory of Immunopathology and Therapeutic Chemistry, CNRS UPR 3572/Laboratory of Excellence MEDALIS, IBMC, University of Strasbourg, Strasbourg, France. Electronic address:

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July 2015

Emerging immune functions of non-hematopoietic stromal cells.

Authors:

Christopher G Mueller Mark Christopher Coles

Front Immunol 2014 12;5:437. Epub 2014 Sep 12.

University of York , York , UK.

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October 2014

Dynamic micelles of mannoside glycolipids are more efficient than polymers for inhibiting HIV-1 trans-infection.

Authors:

Evelyne Schaeffer Laure Dehuyser David Sigwalt Vincent Flacher Serena Bernacchi Olivier Chaloin Jean-Serge Remy Christopher G Mueller Rachid Baati Alain Wagner

Bioconjug Chem 2013 Nov 18;24(11):1813-23. Epub 2013 Oct 18.

Laboratory of Immunopathology and Therapeutic Chemistry, CNRS UPR 3572/Laboratory of Excellence MEDALIS, Institut de Biologie Moléculaire et Cellulaire , 15 rue René Descartes, 67000 Strasbourg, France.

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November 2013

Emerging Functions of RANKL in Lymphoid Tissues.

Authors:

Christopher G Mueller Estelle Hess

Front Immunol 2012 3;3:261. Epub 2012 Sep 3.

CNRS, Laboratory of Therapeutic Immunology and Chemistry, Institut de Biologie Moléculaire et Cellulaire, University of Strasbourg Strasbourg, France.

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September 2012

Synthesis of novel mannoside glycolipid conjugates for inhibition of HIV-1 trans-infection.

Authors:

Laure Dehuyser Evelyne Schaeffer Olivier Chaloin Christopher G Mueller Rachid Baati Alain Wagner

Bioconjug Chem 2012 Sep 7;23(9):1731-9. Epub 2012 Aug 7.

Laboratory of Functional Chemo Systems, CNRS-UdS UMR 7199, Faculté de Pharmacie, Université de Strasbourg, 74 route du Rhin, 67400 Illkirch, France.

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September 2012

RANKL induces organized lymph node growth by stromal cell proliferation.

Authors:

Estelle Hess Vincent Duheron Marion Decossas Frédéric Lézot Ariane Berdal Sylvestre Chea Rachel Golub Mattéo R Bosisio S Lori Bridal Yongwon Choi Hideo Yagita Christopher G Mueller

J Immunol 2012 Feb 30;188(3):1245-54. Epub 2011 Dec 30.

Centre National de la Recherche Scientifique, Laboratoire d'Immunopathologie et Chimie Thérapeutique, Unité Propre de Recherche 9021, Institut de Biologie Moléculaire et Cellulaire, Université de Strasbourg, 67084 Strasbourg, France.

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February 2012

A new organotypic model containing dermal-type macrophages.

Authors:

Nicolas Bechetoille Hortense Vachon Amandine Gaydon Aurelie Boher Thomas Fontaine Evelyne Schaeffer Marion Decossas Valérie André-Frei Christopher G Mueller

Exp Dermatol 2011 Dec 2;20(12):1035-7. Epub 2011 Nov 2.

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December 2011

Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells.

Authors:

Mihai Ciobanu Kuo-Ting Huang Jean-Pierre Daguer Sofia Barluenga Olivier Chaloin Evelyne Schaeffer Christopher G Mueller Daniel A Mitchell Nicolas Winssinger

Chem Commun (Camb) 2011 Sep 25;47(33):9321-3. Epub 2011 Jul 25.

Institut de Science et Ingenierie Supramoleculaires (ISIS), Université de Strasbourg-CNRS, 8 allee Gaspard Monge, 67000 Strasbourg, France.

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September 2011

Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit.

Authors:

Vincent Duheron Estelle Hess Monique Duval Marion Decossas Beatriz Castaneda Jennifer E Klöpper Leonela Amoasii Jean-Baptiste Barbaroux Ifor R Williams Hideo Yagita Josef Penninger Yongwon Choi Frédéric Lézot Richard Groves Ralf Paus Christopher G Mueller

Proc Natl Acad Sci U S A 2011 Mar 14;108(13):5342-7. Epub 2011 Mar 14.

Centre National de la Recherche Scientifique, Laboratory of Therapeutic Immunology and Chemistry, Unité Propre de Recherche 9021, Institut de Biologie Moléculaire et Cellulaire, University of Strasbourg, 67084 Strasbourg, France.

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March 2011

Generation of anti-DC-SIGN monoclonal antibodies capable of blocking HIV-1 gp120 binding and reactive on formalin-fixed tissue.

Authors:

Bertrand Canard Hortense Vachon Thomas Fontaine Jean-Jacques Pin Stéphane Paul Christian Genin Christopher G Mueller

Immunol Lett 2011 Mar 13;135(1-2):165-72. Epub 2010 Nov 13.

Groupe Immunité des Muqueuses et Agents Pathogènes (G.I.M.A.P.) Université Jean Monnet, Faculté de Médecine, 15 rue Ambroise Paré, 42023 Saint Etienne, France.

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March 2011