Christopher G Mathew

Christopher G Mathew

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Christopher G Mathew

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The health and economic burden of lymphatic filariasis prior to mass drug administration programmes.

Clin Infect Dis 2019 Jul 25. Epub 2019 Jul 25.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1093/cid/ciz671DOI Listing
July 2019

The Relationship Between Environmental Exposure and Genetic Architecture of the 2q33 Locus With Esophageal Cancer in South Africa.

Front Genet 2019 1;10:406. Epub 2019 May 1.

Division of Medical Biochemistry and Structural Biology, Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fgene.2019.00406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504765PMC
May 2019

The African Esophageal Cancer Consortium: A Call to Action.

J Glob Oncol 2018 Sep;4:1-9

Katherine Van Loon, University of California, San Francisco, San Francisco, CA; Michael M. Mwachiro, Stephen L. Burgert, and Russell E. White, Tenwek Hospital, Bomet; Diana Menya, Moi University, Eldoret, Kenya; Christian C. Abnet, Gwen Murphy, Natalie Pritchett, and Sanford M. Dawsey, National Cancer Institute, Bethesda, MD; Larry Akoko, Elia Mmbaga, Beatrice Mushi, and Ally Mwanga, Muhimbili University of Health and Allied Sciences, Dar es Salaam; Blandina T. Mmbaga and Amos Mwasamwaja, Kilimanjaro Clinical Research Institute, Moshi, Tanzania; Mathewos Assefa, Addis Ababa University, Addis Ababa, Ethiopia; Steady Chasimpha and Charles Dzamalala, Queen Elizabeth Central Hospital; Charles Dzamalala, Satish Gopal, Bongani Kaimila, and Yohannie Mlombe, University of Malawi College of Medicine, Blantyre; Gift Mulima, Kamuzu Central Hospital, Lilongwe, Malawi; David E. Fleischer, Mayo Clinic, Phoenix, AZ; Satish Gopal, University of North Carolina, Chapel Hill, NC; Prasad G. Iyer and Mark D. Topazian, Mayo Clinic, Rochester, MN; Violet Kayamba and Paul Kelly, University of Zambia, Lusaka, Zambia; Paul Kelly, Queen Mary University of London; Christopher G. Mathew, King's College London, London, United Kingdom; Maria E. Leon, Daniel Middleton, Joachim Schüz, and Valerie McCormack, International Agency for Research on Cancer, Lyon, France; Christopher G. Mathew, University of the Witwatersrand, Johannesburg; and M. Iqbal Parker, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1200/JGO.17.00163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223465PMC
September 2018

The Integrity and Yield of Genomic DNA Isolated from Whole Blood Following Long-Term Storage at -30°C.

Biopreserv Biobank 2018 Apr 3;16(2):106-113. Epub 2018 Jan 3.

3 Division of Human Genetics, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand , Johannesburg, South Africa .

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http://dx.doi.org/10.1089/bio.2017.0050DOI Listing
April 2018

Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis.

Inflamm Bowel Dis 2016 07;22(7):1552-8

*Department of Gastroenterology, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; †Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King's College London, Guy's Hospital, London, United Kingdom; ‡Oral Medicine, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, United Kingdom; §Diabetes and Nutritional Sciences Division, King's College London, London, United Kingdom; ‖Faculty of Health and Environmental Sciences, AUT University, Auckland, New Zealand; ¶Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom; and **Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa.

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http://dx.doi.org/10.1097/MIB.0000000000000844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912233PMC
July 2016

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.

Biol Psychiatry 2014 Mar 17;75(5):386-97. Epub 2013 Jul 17.

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http://dx.doi.org/10.1016/j.biopsych.2013.03.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923972PMC
March 2014

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

Authors:
Stephan Ripke Colm O'Dushlaine Kimberly Chambert Jennifer L Moran Anna K Kähler Susanne Akterin Sarah E Bergen Ann L Collins James J Crowley Menachem Fromer Yunjung Kim Sang Hong Lee Patrik K E Magnusson Nick Sanchez Eli A Stahl Stephanie Williams Naomi R Wray Kai Xia Francesco Bettella Anders D Borglum Brendan K Bulik-Sullivan Paul Cormican Nick Craddock Christiaan de Leeuw Naser Durmishi Michael Gill Vera Golimbet Marian L Hamshere Peter Holmans David M Hougaard Kenneth S Kendler Kuang Lin Derek W Morris Ole Mors Preben B Mortensen Benjamin M Neale Francis A O'Neill Michael J Owen Milica Pejovic Milovancevic Danielle Posthuma John Powell Alexander L Richards Brien P Riley Douglas Ruderfer Dan Rujescu Engilbert Sigurdsson Teimuraz Silagadze August B Smit Hreinn Stefansson Stacy Steinberg Jaana Suvisaari Sarah Tosato Matthijs Verhage James T Walters Douglas F Levinson Pablo V Gejman Kenneth S Kendler Claudine Laurent Bryan J Mowry Michael C O'Donovan Michael J Owen Ann E Pulver Brien P Riley Sibylle G Schwab Dieter B Wildenauer Frank Dudbridge Peter Holmans Jianxin Shi Margot Albus Madeline Alexander Dominique Campion David Cohen Dimitris Dikeos Jubao Duan Peter Eichhammer Stephanie Godard Mark Hansen F Bernard Lerer Kung-Yee Liang Wolfgang Maier Jacques Mallet Deborah A Nertney Gerald Nestadt Nadine Norton Francis A O'Neill George N Papadimitriou Robert Ribble Alan R Sanders Jeremy M Silverman Dermot Walsh Nigel M Williams Brandon Wormley Maria J Arranz Steven Bakker Stephan Bender Elvira Bramon David Collier Benedicto Crespo-Facorro Jeremy Hall Conrad Iyegbe Assen Jablensky Rene S Kahn Luba Kalaydjieva Stephen Lawrie Cathryn M Lewis Kuang Lin Don H Linszen Ignacio Mata Andrew McIntosh Robin M Murray Roel A Ophoff John Powell Dan Rujescu Jim Van Os Muriel Walshe Matthias Weisbrod Durk Wiersma Peter Donnelly Ines Barroso Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden P Corvin Panos Deloukas Audrey Duncanson Janusz Jankowski Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas W Wood Chris C A Spencer Gavin Band Céline Bellenguez Colin Freeman Garrett Hellenthal Eleni Giannoulatou Matti Pirinen Richard D Pearson Amy Strange Zhan Su Damjan Vukcevic Peter Donnelly Cordelia Langford Sarah E Hunt Sarah Edkins Rhian Gwilliam Hannah Blackburn Suzannah J Bumpstead Serge Dronov Matthew Gillman Emma Gray Naomi Hammond Alagurevathi Jayakumar Owen T McCann Jennifer Liddle Simon C Potter Radhi Ravindrarajah Michelle Ricketts Avazeh Tashakkori-Ghanbaria Matthew J Waller Paul Weston Sara Widaa Pamela Whittaker Ines Barroso Panos Deloukas Christopher G Mathew Jenefer M Blackwell Matthew A Brown Aiden P Corvin Mark I McCarthy Chris C A Spencer Elvira Bramon Aiden P Corvin Michael C O'Donovan Kari Stefansson Edward Scolnick Shaun Purcell Steven A McCarroll Pamela Sklar Christina M Hultman Patrick F Sullivan

Nat Genet 2013 Oct 25;45(10):1150-9. Epub 2013 Aug 25.

1] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [3].

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http://dx.doi.org/10.1038/ng.2742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827979PMC
October 2013

Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population.

Carcinogenesis 2012 Nov 3;33(11):2155-61. Epub 2012 Aug 3.

Department of Medical and Molecular Genetics, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1093/carcin/bgs262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584964PMC
November 2012

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Authors:
Zhan Su Laura J Gay Amy Strange Claire Palles Gavin Band David C Whiteman Francesco Lescai Cordelia Langford Manoj Nanji Sarah Edkins Anouk van der Winkel David Levine Peter Sasieni Céline Bellenguez Kimberley Howarth Colin Freeman Nigel Trudgill Art T Tucker Matti Pirinen Maikel P Peppelenbosch Luc J W van der Laan Ernst J Kuipers Joost P H Drenth Wilbert H Peters John V Reynolds Dermot P Kelleher Ross McManus Heike Grabsch Hans Prenen Raf Bisschops Kausila Krishnadath Peter D Siersema Jantine W P M van Baal Mark Middleton Russell Petty Richard Gillies Nicola Burch Pradeep Bhandari Stuart Paterson Cathryn Edwards Ian Penman Kishor Vaidya Yeng Ang Iain Murray Praful Patel Weimin Ye Paul Mullins Anna H Wu Nigel C Bird Helen Dallal Nicholas J Shaheen Liam J Murray Konrad Koss Leslie Bernstein Yvonne Romero Laura J Hardie Rui Zhang Helen Winter Douglas A Corley Simon Panter Harvey A Risch Brian J Reid Ian Sargeant Marilie D Gammon Howard Smart Anjan Dhar Hugh McMurtry Haythem Ali Geoffrey Liu Alan G Casson Wong-Ho Chow Matt Rutter Ashref Tawil Danielle Morris Chuka Nwokolo Peter Isaacs Colin Rodgers Krish Ragunath Chris MacDonald Chris Haigh David Monk Gareth Davies Saj Wajed David Johnston Michael Gibbons Sue Cullen Nicholas Church Ruth Langley Michael Griffin Derek Alderson Panos Deloukas Sarah E Hunt Emma Gray Serge Dronov Simon C Potter Avazeh Tashakkori-Ghanbaria Mark Anderson Claire Brooks Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden Corvin Audrey Duncanson Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas Wood Gosia Trynka Cisca Wijmenga Jean-Baptiste Cazier Paul Atherfold Anna M Nicholson Nichola L Gellatly Deborah Glancy Sheldon C Cooper David Cunningham Tore Lind Julie Hapeshi David Ferry Barrie Rathbone Julia Brown Sharon Love Stephen Attwood Stuart MacGregor Peter Watson Scott Sanders Weronica Ek Rebecca F Harrison Paul Moayyedi John de Caestecker Hugh Barr Elia Stupka Thomas L Vaughan Leena Peltonen Chris C A Spencer Ian Tomlinson Peter Donnelly Janusz A Z Jankowski

Nat Genet 2012 Oct 9;44(10):1131-6. Epub 2012 Sep 9.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.2408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459818PMC
October 2012

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.

Nat Genet 2012 Feb 5;44(3):328-33. Epub 2012 Feb 5.

Wellcome Trust Centre for Human Genetics, University of Oxford, UK.

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http://www.nature.com/articles/ng.1081
Publisher Site
http://dx.doi.org/10.1038/ng.1081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303115PMC
February 2012

Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa.

Carcinogenesis 2011 Dec 16;32(12):1855-61. Epub 2011 Sep 16.

Department of Medical and Molecular Genetics, King's College London, King's Health Partners, Guy's Hospital, London SE1 9RT, UK.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
Publisher Site
http://dx.doi.org/10.1093/carcin/bgr211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220606PMC
December 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.

Nat Genet 2011 Jul 10;43(8):761-7. Epub 2011 Jul 10.

Medical Research Council (MRC) Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/ng.873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640413PMC
July 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084597PMC
March 2011

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

Hum Mol Genet 2010 Dec 21;19(24):4930-8. Epub 2010 Sep 21.

Gastrointestinal Unit, School of Clinical and Molecular Medicine, Western General Hospital, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.1093/hmg/ddq411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989891PMC
December 2010

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Nat Genet 2010 Nov 17;42(11):985-90. Epub 2010 Oct 17.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749730PMC
November 2010

Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

Authors:
Jason Z Liu Federica Tozzi Dawn M Waterworth Sreekumar G Pillai Pierandrea Muglia Lefkos Middleton Wade Berrettini Christopher W Knouff Xin Yuan Gérard Waeber Peter Vollenweider Martin Preisig Nicholas J Wareham Jing Hua Zhao Ruth J F Loos Inês Barroso Kay-Tee Khaw Scott Grundy Philip Barter Robert Mahley Antero Kesaniemi Ruth McPherson John B Vincent John Strauss James L Kennedy Anne Farmer Peter McGuffin Richard Day Keith Matthews Per Bakke Amund Gulsvik Susanne Lucae Marcus Ising Tanja Brueckl Sonja Horstmann H-Erich Wichmann Rajesh Rawal Norbert Dahmen Claudia Lamina Ozren Polasek Lina Zgaga Jennifer Huffman Susan Campbell Jaspal Kooner John C Chambers Mary Susan Burnett Joseph M Devaney Augusto D Pichard Kenneth M Kent Lowell Satler Joseph M Lindsay Ron Waksman Stephen Epstein James F Wilson Sarah H Wild Harry Campbell Veronique Vitart Muredach P Reilly Mingyao Li Liming Qu Robert Wilensky William Matthai Hakon H Hakonarson Daniel J Rader Andre Franke Michael Wittig Arne Schäfer Manuela Uda Antonio Terracciano Xiangjun Xiao Fabio Busonero Paul Scheet David Schlessinger David St Clair Dan Rujescu Gonçalo R Abecasis Hans Jörgen Grabe Alexander Teumer Henry Völzke Astrid Petersmann Ulrich John Igor Rudan Caroline Hayward Alan F Wright Ivana Kolcic Benjamin J Wright John R Thompson Anthony J Balmforth Alistair S Hall Nilesh J Samani Carl A Anderson Tariq Ahmad Christopher G Mathew Miles Parkes Jack Satsangi Mark Caulfield Patricia B Munroe Martin Farrall Anna Dominiczak Jane Worthington Wendy Thomson Steve Eyre Anne Barton Vincent Mooser Clyde Francks Jonathan Marchini

Nat Genet 2010 May 25;42(5):436-40. Epub 2010 Apr 25.

Department of Statistics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612983PMC
May 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

Nat Genet 2009 Dec 15;41(12):1330-4. Epub 2009 Nov 15.

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http://dx.doi.org/10.1038/ng.483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812019PMC
December 2009

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267927PMC
December 2009

Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease.

Am J Hum Genet 2009 Feb 29;84(2):178-87. Epub 2009 Jan 29.

Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

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http://dx.doi.org/10.1016/j.ajhg.2008.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668013PMC
February 2009

Cancer incidence in relatives of British Fanconi Anaemia patients.

BMC Cancer 2008 Sep 11;8:257. Epub 2008 Sep 11.

Cancer Genetics Program, Departments of Human Genetics and Oncology, Sir M.B. Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1186/1471-2407-8-257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556683PMC
September 2008

Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation.

Eur J Hum Genet 2008 May 23;16(5):619-25. Epub 2008 Jan 23.

Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1038/sj.ejhg.5201996DOI Listing
May 2008

New links to the pathogenesis of Crohn disease provided by genome-wide association scans.

Nat Rev Genet 2008 Jan;9(1):9-14

Division of Genetics and Molecular Medicine, King's College London School of Medicine, 8th Floor Guy's Tower, Guy's Hospital, London SE1 9RT, UK.

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http://www.nature.com/articles/nrg2203
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January 2008

Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene.

Genomics 2007 Oct 24;90(4):493-501. Epub 2007 Aug 24.

Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1016/j.ygeno.2007.07.009DOI Listing
October 2007

A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.

Gastroenterology 2007 May 24;132(5):1665-71. Epub 2007 Mar 24.

Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1053/j.gastro.2007.03.034DOI Listing
May 2007

Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population.

Int J Colorectal Dis 2007 Apr 31;22(4):419-24. Epub 2006 May 31.

Department of Medical & Molecular Genetics, King's College London School of Medicine, 8th Floor Guy's Tower, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1007/s00384-006-0151-4DOI Listing
April 2007

Recruiting first-degree relatives for prevention research: a comparison of clinician and proband-led methods of contact in Crohn's disease.

Eur J Hum Genet 2006 Dec 26;14(12):1263-8. Epub 2006 Jul 26.

Department of Psychology, Health Psychology Section, Institute of Psychiatry, King's College London, London, UK.

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http://dx.doi.org/10.1038/sj.ejhg.5201699DOI Listing
December 2006

Detection of muramyl dipeptide-sensing pathway defects in patients with Crohn's disease.

Inflamm Bowel Dis 2006 Jul;12(7):598-605

Institute of Cell and Molecular Science, Barts & The London, Queen Mary's School of Medicine & Dentistry, London, UK.

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http://dx.doi.org/10.1097/01.ibd.0000225344.21979.89DOI Listing
July 2006

Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.

DNA Repair (Amst) 2006 May 18;5(5):629-40. Epub 2006 Apr 18.

Department of Medical and Molecular Genetics, King's College London School of Medicine at Guy's Hospital, London SE1 9RT, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S156878640600061
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http://dx.doi.org/10.1016/j.dnarep.2006.02.007DOI Listing
May 2006

Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15.

Hum Mutat 2006 Jan;27(1):44-54

Department of Medical and Molecular Genetics, Guy's, King's and St. Thomas' School of Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/humu.20264DOI Listing
January 2006

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

Nat Genet 2005 Sep 21;37(9):958-63. Epub 2005 Aug 21.

Division of Experimental Hematology, Cincinnati Children's Hospital Research Foundation and University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.

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http://www.nature.com/articles/ng1626
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http://dx.doi.org/10.1038/ng1626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704909PMC
September 2005

The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J.

Nat Genet 2005 Sep 21;37(9):934-5. Epub 2005 Aug 21.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Van der Boechorststraat 7, NL-1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng1625DOI Listing
September 2005

Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways.

Hum Mol Genet 2004 Jun 28;13(12):1241-8. Epub 2004 Apr 28.

Division of Genetics and Development, Guy's, King's and St Thomas's School of Medicine, King's College London, UK.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddh135DOI Listing
June 2004

Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes.

Blood 2004 Apr 20;103(7):2498-503. Epub 2003 Nov 20.

Department of Clinical Genetics and Human Genetics, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2003-08-2915DOI Listing
April 2004

Genetics of inflammatory bowel disease: progress and prospects.

Hum Mol Genet 2004 Apr 5;13 Spec No 1:R161-8. Epub 2004 Feb 5.

Division of Genetics and Development, Guy's King's and St Thomas' School of Medicine, King's College London, 8th Floor Guy's Tower, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1093/hmg/ddh079DOI Listing
April 2004

Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia.

Br J Haematol 2003 Nov;123(3):469-71

Department of Medical and Molecular Genetics, Division of Genetics and Development Guy's, King's and St Thomas's School of Medicine, King's College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1046/j.1365-2141.2003.04640.xDOI Listing
November 2003

Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1.

Hum Mol Genet 2003 Oct 5;12(19):2503-10. Epub 2003 Aug 5.

Division of Genetics and Development, Guy's, King's and St Thomas' School of Medicine, King's College London, UK.

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http://dx.doi.org/10.1093/hmg/ddg266DOI Listing
October 2003

Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors.

Nat Med 2003 May 7;9(5):568-74. Epub 2003 Apr 7.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Guy's King's and St. Thomas' School of Medicine, London, UK.

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http://www.nature.com/articles/nm852
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May 2003

Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

Am J Hum Genet 2003 Apr 3;72(4):1018-22. Epub 2003 Mar 3.

Division of Medical and Molecular Genetics, Guy's, King's, and Thomas's School of Medicine, King's College London, Guy's Hospital, London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180331PMC
http://dx.doi.org/10.1086/373880DOI Listing
April 2003

Interaction of FANCD2 and NBS1 in the DNA damage response.

Nat Cell Biol 2002 Dec;4(12):913-20

Department of Pediatric Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/ncb879DOI Listing
December 2002