Publications by authors named "Christopher G Kanakry"

40Publications

Editorial: The Immunobiology of HLA-Haploidentical Hematopoietic Cell Transplantation.

Front Immunol 2020 20;11:1031. Epub 2020 May 20.

Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.3389/fimmu.2020.01031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251076PMC
May 2020

Mechanisms of Graft-versus-Host Disease Prevention by Post-transplantation Cyclophosphamide: An Evolving Understanding.

Front Immunol 2019 29;10:2668. Epub 2019 Nov 29.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2019.02668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895959PMC
November 2019

Optimized Timing of Post-Transplantation Cyclophosphamide in MHC-Haploidentical Murine Hematopoietic Cell Transplantation.

Biol Blood Marrow Transplant 2020 02 2;26(2):230-241. Epub 2019 Oct 2.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.09.030DOI Listing
February 2020

Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression.

J Clin Invest 2019 03 26;129(6):2357-2373. Epub 2019 Mar 26.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute (NCI).

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http://dx.doi.org/10.1172/JCI124218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546453PMC
March 2019

Successful Bone Marrow Transplantation for XMEN: Hemorrhagic Risk Uncovered.

J Clin Immunol 2019 01 23;39(1):1-3. Epub 2018 Nov 23.

Experimental Transplantation and Immunology Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), 10 Center Drive, Bethesda, MD, 20892, USA.

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http://link.springer.com/10.1007/s10875-018-0573-0
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http://dx.doi.org/10.1007/s10875-018-0573-0DOI Listing
January 2019

Teaching a Young Dog New Tricks: Modifications to the Post-Transplantation Cyclophosphamide Haploidentical Transplantation Platform.

Biol Blood Marrow Transplant 2018 06 10;24(6):1108-1110. Epub 2018 Apr 10.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.bbmt.2018.04.004DOI Listing
June 2018

Have haploidentical transplants replaced umbilical cord transplants for acute leukemias?

Curr Opin Hematol 2018 03;25(2):103-111

Division of Hematologic Malignancies, Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/MOH.0000000000000412DOI Listing
March 2018

Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide.

JCI Insight 2016;1(5). Epub 2016 Apr 21.

Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA; Department of Medicine, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1172/jci.insight.86252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874509PMC
April 2016

Modern approaches to HLA-haploidentical blood or marrow transplantation.

Nat Rev Clin Oncol 2016 Feb 31;13(2):132. Epub 2015 Dec 31.

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http://dx.doi.org/10.1038/nrclinonc.2015.234DOI Listing
February 2016

Modern approaches to HLA-haploidentical blood or marrow transplantation.

Nat Rev Clin Oncol 2016 Jan 25;13(1):10-24. Epub 2015 Aug 25.

Sidney Kimmel Comprehensive Cancer Center, 1650 Orleans Street, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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https://www.nature.com/articles/nrclinonc.2015.128.pdf
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http://www.nature.com/articles/nrclinonc.2015.128
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http://dx.doi.org/10.1038/nrclinonc.2015.128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695979PMC
January 2016

Alternative Donor Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia.

Semin Hematol 2015 Jul 18;52(3):232-42. Epub 2015 Mar 18.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1053/j.seminhematol.2015.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483196PMC
July 2015

Immunomodulatory Drugs: Immune Checkpoint Agents in Acute Leukemia.

Curr Drug Targets 2017 ;18(3):315-331

Cancer Research Building I, Room 346, 1650 Orleans Street, Baltimore, MD 21287, United States.

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http://dx.doi.org/10.2174/1389450116666150518095346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729661PMC
September 2017

Situational aldehyde dehydrogenase expression by regulatory T cells may explain the contextual duality of cyclophosphamide as both a pro-inflammatory and tolerogenic agent.

Oncoimmunology 2015 Mar 20;4(3):e974393. Epub 2015 Mar 20.

Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins University School of Medicine ; Baltimore, MD, USA.

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http://dx.doi.org/10.4161/2162402X.2014.974393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404790PMC
March 2015

Multi-institutional study of post-transplantation cyclophosphamide as single-agent graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation using myeloablative busulfan and fludarabine conditioning.

J Clin Oncol 2014 Nov 29;32(31):3497-505. Epub 2014 Sep 29.

Christopher G. Kanakry, Marta Medeot, Richard J. Jones, Leo Luznik, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD; Paul V. O'Donnell, Terry Furlong, Marco Mielcarek, Fred Hutchinson Cancer Research Center, Seattle, WA; Marcos J. de Lima, Wei Wei, Richard E. Champlin, Peter F. Thall, Borje S. Andersson, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://ascopubs.org/doi/10.1200/JCO.2013.54.0625
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http://dx.doi.org/10.1200/JCO.2013.54.0625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209101PMC
November 2014

Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice.

Blood 2014 Sep 18;124(13):2131-41. Epub 2014 Aug 18.

Division of Hematologic Malignancies, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD;

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http://dx.doi.org/10.1182/blood-2013-10-525873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186542PMC
September 2014

Are alternative donors really still "alternative?".

Biol Blood Marrow Transplant 2014 Oct 31;20(10):1463-4. Epub 2014 Jul 31.

Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596228PMC
October 2014

Aldehyde dehydrogenase expression drives human regulatory T cell resistance to posttransplantation cyclophosphamide.

Sci Transl Med 2013 Nov;5(211):211ra157

The Sidney Kimmel Comprehensive Cancer Center and Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/scitranslmed.3006960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155575PMC
November 2013

Neuregulin-1 regulates cell adhesion via an ErbB2/phosphoinositide-3 kinase/Akt-dependent pathway: potential implications for schizophrenia and cancer.

PLoS One 2007 Dec 26;2(12):e1369. Epub 2007 Dec 26.

Genes, Cognition and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0001369PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2147048PMC
December 2007