Publications by authors named "Christopher Dunham"

52Publications

Pathologic Skull Fracture in a Near-Term Neonate with Arthrochalasia Type Ehlers-Danlos Syndrome: A Case Report.

Fetal Pediatr Pathol 2020 Apr 27:1-6. Epub 2020 Apr 27.

Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia, and University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1080/15513815.2020.1753269DOI Listing
April 2020

Pontine Embryonal Tumor With Multilayered Rosettes: An Autopsy Case Exhibiting Extensive Posttreatment Glial and Neuronal Maturation.

Pediatr Dev Pathol 2020 Aug 13;23(4):326-331. Epub 2020 Apr 13.

Division of Anatomical Pathology, Department of Pathology and Laboratory Medicine, Children and Women's Health Centre of BC, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1177/1093526620912645DOI Listing
August 2020

Loss of BRG1 () Immunoexpression in a Pediatric Non-Central Nervous System Tumor Cohort.

Pediatr Dev Pathol 2020 Mar-Apr;23(2):132-138. Epub 2019 Aug 12.

Division of Anatomical Pathology, British Columbia Children's Hospital and Women's Hospital and Health Center, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1177/1093526619869154DOI Listing
August 2019

mTOR Inhibitors as a New Therapeutic Strategy in Treatment Resistant Epilepsy in Hemimegalencephaly: A Case Report.

J Child Neurol 2019 03 5;34(3):132-138. Epub 2018 Dec 5.

1 Division of Neurology, University of British Columbia, BC Children's Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1177/0883073818813238DOI Listing
March 2019

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Clinical, imaging, and immunohistochemical characteristics of focal cortical dysplasia Type II extratemporal epilepsies in children: analyses of an institutional case series.

J Neurosurg Pediatr 2017 Feb 25;19(2):182-195. Epub 2016 Nov 25.

Division of Anatomical Pathology, Department of Pathology and Laboratory Medicine, and.

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http://dx.doi.org/10.3171/2016.8.PEDS1686DOI Listing
February 2017

Phenotypic evolution of UNC80 loss of function.

Am J Med Genet A 2016 12 11;170(12):3106-3114. Epub 2016 Aug 11.

NIH Undiagnosed Diseases Program, Common Fund, Office of the Director, NIH, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/ajmg.a.37929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671762PMC
December 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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http://dx.doi.org/10.1200/JCO.2015.65.7825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962737PMC
July 2016

Histopathology of the filum terminale in children with and without tethered cord syndrome with attention to the elastic tissue within the filum.

Childs Nerv Syst 2016 Sep 28;32(9):1683-92. Epub 2016 May 28.

Division of Neurosurgery, Department of Surgery, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1007/s00381-016-3123-1DOI Listing
September 2016

Assessing the accuracy of death records and pre-mortem clinical diagnoses in children diagnosed with brain tumors: A retrospective chart review of children in British Columbia, Canada.

Pathol Res Pract 2015 Oct 23;211(10):748-53. Epub 2015 Jun 23.

Department of Radiation Oncology, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada; Department of Surgery, University of British Columbia, 950 West 10th Avenue, Vancouver, British Columbia V5Z 1M9, Canada.

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http://dx.doi.org/10.1016/j.prp.2015.06.008DOI Listing
October 2015

Cerebellar cavernous malformation in pediatric patients: defining clinical, neuroimaging, and therapeutic characteristics.

J Neurosurg Pediatr 2015 Sep 22;16(3):256-66. Epub 2015 May 22.

Division of Pediatric Neurosurgery, British Columbia Children's Hospital and Department of Surgery, University of British Columbia;

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http://dx.doi.org/10.3171/2015.1.PEDS14366DOI Listing
September 2015

Radiological features of infantile glioblastoma and desmoplastic infantile tumors: British Columbia's Children's Hospital experience.

J Neurosurg Pediatr 2015 Aug 8;16(2):119-25. Epub 2015 May 8.

Divisions of 1 Neurosurgery and.

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http://dx.doi.org/10.3171/2014.10.PEDS13634DOI Listing
August 2015

Evolution of a Pediatric Primary Cerebral ALK-1-Positive Anaplastic Large Cell Lymphoma on Serial MRI.

Pediatr Neurosurg 2015 17;50(3):145-51. Epub 2015 Apr 17.

British Columbia Children's Hospital, University of British Columbia, Vancouver, B.C., Canada.

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https://www.karger.com/Article/FullText/380769
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http://dx.doi.org/10.1159/000380769DOI Listing
April 2016

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.

Lancet Oncol 2015 May 14;16(5):569-82. Epub 2015 Apr 14.

Division of Hematology-Oncology, University of Toronto, Toronto, ON, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)70114-2DOI Listing
May 2015

Magnetic resonance imaging in the encephalopathic term newborn.

Curr Pediatr Rev 2014 ;10(1):28-36

The Hospital for Sick Children, Division of Neurology, 555 University Street, 6546 Hill Wing, Toronto (Ontario), M5G 1X8, Canada.

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http://dx.doi.org/10.2174/157339631001140408120336DOI Listing
March 2015

Granulomatous herpes simplex encephalitis in an infant with multicystic encephalopathy: a distinct clinicopathologic entity?

Pediatr Neurol 2014 Apr 14;50(4):392-6. Epub 2013 Dec 14.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada; Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia, Vancouver, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S08878994130074
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http://dx.doi.org/10.1016/j.pediatrneurol.2013.12.008DOI Listing
April 2014

Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children.

Cancer Res 2013 Nov 9;73(22):6734-44. Epub 2013 Sep 9.

Authors' Affiliations: Department of Pediatrics; Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine; Division of Pediatric Neurosurgery, Department of Surgery, BC Children's Hospital, University of British Columbia; Department of Pathology and Laboratory Medicine, Centre for Applied Genomics, British Columbia Cancer Agency, Vancouver, British Columbia; Division of Neurosurgery, Department of Surgery, Faculty of Health Sciences, McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton; The Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children, Toronto, Ontario; Pediatric Oncology Experimental Therapeutics Investigators Consortium (POETIC) Laboratory for Pre-Clinical and Drug Discovery Studies, Division of Pediatric Oncology, Alberta Children's Hospital, Calgary, Alberta, Canada; and Division of Pediatric Neuro-Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-4331DOI Listing
November 2013

Overcoming resistance to Sonic Hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.

Pediatr Blood Cancer 2014 Jan 12;61(1):107-15. Epub 2013 Aug 12.

Department of Pediatrics, British Columbia Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/pbc.24675DOI Listing
January 2014

Cribriform neuroepithelial tumor or atypical teratoid/rhabdoid tumor?

J Neurosurg Pediatr 2013 Apr 8;11(4):486-8. Epub 2013 Feb 8.

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http://dx.doi.org/10.3171/2012.3.PEDS12168DOI Listing
April 2013

Malignant desmoplastic infantile astrocytoma? a case report and review of the literature.

Clin Neuropathol 2013 Mar-Apr;32(2):100-6

Department of Surgery, Division of Neurosurgery, Children's and Women's Health Centre of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.5414/NP300548DOI Listing
June 2013

Possible differentiation of cerebral glioblastoma into pleomorphic xanthoastrocytoma: an unusual case in an infant.

J Neurosurg Pediatr 2012 May;9(5):517-23

Department of Surgery, Division of Neurosurgery, Children's and Women's Health Centre of British Columbia and University of British Columbia, Vancouver, British Columbia.

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https://thejns.org/view/journals/j-neurosurg-pediatr/9/5/art
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http://dx.doi.org/10.3171/2012.1.PEDS11326DOI Listing
May 2012

Infant brain tumors: a neuropathologic population-based institutional reappraisal.

Hum Pathol 2012 Oct 10;43(10):1668-76. Epub 2012 Apr 10.

Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, Vancouver, British Columbia.

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http://dx.doi.org/10.1016/j.humpath.2011.12.011DOI Listing
October 2012

Intracranial tumors in infants: long-term functional outcome, survival, and its predictors.

Childs Nerv Syst 2012 Apr 4;28(4):547-55. Epub 2012 Feb 4.

Division of Pediatric Neurosurgery, Department of Surgery, University of British Columbia and British Columbia Children's Hospital, Vancouver, BC, Canada V6H 3V4.

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http://dx.doi.org/10.1007/s00381-012-1707-yDOI Listing
April 2012

Atypical teratoid rhabdoid tumors (ATRTs): the British Columbia's Children's Hospital's experience, 1986-2006.

Brain Pathol 2012 Sep 13;22(5):625-35. Epub 2012 Feb 13.

Division of Hematology, Oncology and Bone Marrow Transplantation, British Columbia Children's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/j.1750-3639.2011.00561.xDOI Listing
September 2012

Congenital stridor in the context of Chiari malformation type II: the etiological role of vernix caseosa granulomatous meningitis.

J Neurosurg Pediatr 2011 Oct;8(4):372-6

Division of Neonatology, Children’s and Women’s Health Center of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.3171/2011.7.PEDS11208DOI Listing
October 2011

Pediatric brain tumors: a histologic and genetic update on commonly encountered entities.

Semin Diagn Pathol 2010 Aug;27(3):147-59

Division of Anatomic Pathology, University of British Columbia, Children's and Women's Health Center of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1053/j.semdp.2010.04.003DOI Listing
August 2010

Microfibrillar collagen hemostat-induced necrotizing granulomatous inflammation developing after craniotomy: a pediatric case series.

J Neurosurg Pediatr 2010 Oct;6(4):385-92

Department of Pathology and Laboratory Medicine, Division of Anatomic Pathology, Children's and Women's Health Centre of British Columbia, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.3171/2010.8.PEDS10248DOI Listing
October 2010

Neuronal Intranuclear Inclusion Disease presenting as juvenile Parkinsonism.

Can J Neurol Sci 2010 Mar;37(2):213-8

Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta.

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http://dx.doi.org/10.1017/s031716710000994xDOI Listing
March 2010

Congenital gliosarcoma: detailed clinicopathologic documentation of a rare neoplasm.

Pediatr Dev Pathol 2009 Sep-Oct;12(5):398-403

Division of Neonatology, Children's and Women's Health Centre of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.2350/09-01-0592-CR.1DOI Listing
December 2009

Answer to case of the month # 132. Adult ileocolic intussusception secondary to a submucosal lipoma.

Can Assoc Radiol J 2008 Apr;59(2):89-91

Department of Diagnostic Imaging, Foothills Medical Centre, Calgary, AB.

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April 2008

Primary intracerebral angiomatoid fibrous histiocytoma: report of a case with a t(12;22)(q13;q12) causing type 1 fusion of the EWS and ATF-1 genes.

Am J Surg Pathol 2008 Mar;32(3):478-84

Division of Neuropathology, Washington University School of Medicine, St Louis, MO 63110, USA

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http://dx.doi.org/10.1097/PAS.0b013e3181453451DOI Listing
March 2008

Atypical teratoid/rhabdoid tumor arising in the setting of a pleomorphic xanthoastrocytoma.

J Neurooncol 2007 Sep 13;84(2):217-22. Epub 2007 Apr 13.

Division of Neuropathology, Department of Neurological Sciences, Christian Medical College, Vellore, India.

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http://dx.doi.org/10.1007/s11060-007-9361-zDOI Listing
September 2007

MRI findings in an immunocompromised boy with CNS fungal infection.

Can J Neurol Sci 2007 Feb;34(1):88-91

Department of Neurology, University of California, San Francisco, USA.

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http://dx.doi.org/10.1017/s0317167100005850DOI Listing
February 2007

Embryonal tumor with abundant neuropil and true rosettes (ETANTR): report of a case with prominent neurocytic differentiation.

J Neurooncol 2007 Aug 28;84(1):91-8. Epub 2007 Feb 28.

Division of Neuropathology, Department of Pathology and Immunology, Washington University School of Medicine, 660 S. Euclid, Campus Box, 8118, St. Louis, MO 63110, USA.

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http://www.springerlink.com/index/7XJ12488325U1153.pdf
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http://link.springer.com/content/pdf/10.1007/s11060-007-9346
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http://www.researchgate.net/profile/Sameh_Hashem/publication
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http://link.springer.com/10.1007/s11060-007-9346-y
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http://dx.doi.org/10.1007/s11060-007-9346-yDOI Listing
August 2007

Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas.

J Clin Oncol 2006 Dec;24(34):5419-26

Division of Neuropathology, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://ascopubs.org/doi/10.1200/JCO.2006.08.1497
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http://dx.doi.org/10.1200/JCO.2006.08.1497DOI Listing
December 2006