Publications by authors named "Christopher D Freel"

24Publications

Cellular mechanisms controlling caspase activation and function.

Cold Spring Harb Perspect Biol 2013 Jun 1;5(6). Epub 2013 Jun 1.

Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1101/cshperspect.a008672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660825PMC
June 2013

Rsk-mediated phosphorylation and 14-3-3ɛ binding of Apaf-1 suppresses cytochrome c-induced apoptosis.

EMBO J 2012 Mar 13;31(5):1279-92. Epub 2012 Jan 13.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1038/emboj.2011.491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297998PMC
March 2012

Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc.

EMBO J 2010 Sep 10;29(18):3196-207. Epub 2010 Aug 10.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1038/emboj.2010.191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944066PMC
September 2010

Emi2-mediated inhibition of E2-substrate ubiquitin transfer by the anaphase-promoting complex/cyclosome through a D-box-independent mechanism.

Mol Biol Cell 2010 Aug 9;21(15):2589-97. Epub 2010 Jun 9.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1091/mbc.E09-08-0708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912346PMC
August 2010

PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation.

Nat Cell Biol 2009 May 26;11(5):644-51. Epub 2009 Apr 26.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1038/ncb1871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788612PMC
May 2009

Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.

Mol Biol Cell 2008 Aug 11;19(8):3536-43. Epub 2008 Jun 11.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1091/mbc.e08-04-0417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488281PMC
August 2008

Mitochondrial localization of Reaper to promote inhibitors of apoptosis protein degradation conferred by GH3 domain-lipid interactions.

J Biol Chem 2008 Jan 12;283(1):367-79. Epub 2007 Nov 12.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1074/jbc.M708931200DOI Listing
January 2008

Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A.

Proc Natl Acad Sci U S A 2007 Oct 19;104(42):16564-9. Epub 2007 Sep 19.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0707537104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034268PMC
October 2007

Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation.

Curr Biol 2007 Jul 5;17(14):1181-9. Epub 2007 Jul 5.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.cub.2007.05.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2034293PMC
July 2007

Predicted light scattering from particles observed in human age-related nuclear cataracts using mie scattering theory.

Invest Ophthalmol Vis Sci 2007 Jan;48(1):303-12

Department of Cell and Developmental Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1167/iovs.06-0480DOI Listing
January 2007

A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25.

Mol Biol Cell 2006 Apr 8;17(4):1779-89. Epub 2006 Feb 8.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1091/mbc.e05-08-0751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415323PMC
April 2006

Cataract formation in a strain of rats selected for high oxidative stress.

Exp Eye Res 2004 Nov;79(5):595-612

Department of Cell and Developmental Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.exer.2004.06.008DOI Listing
November 2004

Distribution, spherical structure and predicted Mie scattering of multilamellar bodies in human age-related nuclear cataracts.

Exp Eye Res 2004 Oct;79(4):563-76

Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1016/j.exer.2004.05.017DOI Listing
October 2004

Simultaneous stretching and contraction of stress fibers in vivo.

Mol Biol Cell 2004 Jul 7;15(7):3497-508. Epub 2004 May 7.

Department of Cell and Developmental Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1091/mbc.e03-09-0696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC452600PMC
July 2004

Ultrastructural characterization and Fourier analysis of fiber cell cytoplasm in the hyperbaric oxygen treated guinea pig lens opacification model.

Exp Eye Res 2003 Apr;76(4):405-15

Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7090, USA.

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http://dx.doi.org/10.1016/s0014-4835(03)00004-6DOI Listing
April 2003

Analysis of nuclear fiber cell compaction in transparent and cataractous diabetic human lenses by scanning electron microscopy.

BMC Ophthalmol 2003 Jan 6;3. Epub 2003 Jan 6.

Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140319PMC
http://dx.doi.org/10.1186/1471-2415-3-1DOI Listing
January 2003

Fourier analysis of cytoplasmic texture in nuclear fiber cells from transparent and cataractous human and animal lenses.

Exp Eye Res 2002 Jun;74(6):689-702

Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7090, USA.

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http://dx.doi.org/10.1006/exer.2001.1166DOI Listing
June 2002