Christopher D Byrne

Christopher D Byrne

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Christopher D Byrne

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Prevalence of prediabetes and diabetes in children and adolescents with biopsy-proven non-alcoholic fatty liver disease.

J Hepatol 2019 Oct 4;71(4):802-810. Epub 2019 Jul 4.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278193039
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http://dx.doi.org/10.1016/j.jhep.2019.06.023DOI Listing
October 2019

Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin Users.

J Clin Med 2019 Oct 1;8(10). Epub 2019 Oct 1.

Department of Preventive Medicine and Institute of Occupational and Environmental Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Korea.

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http://dx.doi.org/10.3390/jcm8101571DOI Listing
October 2019

Decreased lung function is associated with risk of developing non-alcoholic fatty liver disease: A longitudinal cohort study.

PLoS One 2019 23;14(1):e0208736. Epub 2019 Jan 23.

Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208736PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343945PMC
September 2019

Association Between Nonalcoholic Fatty Liver Disease and Reduced Bone Mineral Density in Children: A Meta-Analysis.

Hepatology 2019 Sep 18;70(3):812-823. Epub 2019 Mar 18.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1002/hep.30538DOI Listing
September 2019

PNPLA3 rs738409 is associated with renal glomerular and tubular injury in NAFLD patients with persistently normal ALT levels.

Liver Int 2019 Sep 13. Epub 2019 Sep 13.

NAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.1111/liv.14251DOI Listing
September 2019

Multi-drug approaches to NASH: what's in the development pipeline?

Expert Opin Investig Drugs 2019 Sep 23:1-8. Epub 2019 Sep 23.

Human Development and Health, Faculty of Medicine, University of Southampton , Southampton , UK.

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http://dx.doi.org/10.1080/13543784.2020.1668926DOI Listing
September 2019

Marine omega-3 fatty acid supplementation in non-alcoholic fatty liver disease: Plasma proteomics in the randomized WELCOME* trial.

Clin Nutr 2019 Aug 17;38(4):1952-1955. Epub 2018 Aug 17.

Institute for Life Sciences, University of Southampton, Southampton, UK; Cancer Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; Proteome Exploration Laboratory of the Beckman Institute, California Institute of Technology, Pasadena, CA, 91125, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2018.07.037DOI Listing
August 2019

Plasma N-terminal propeptide of type III procollagen accurately predicts liver fibrosis severity in children with non-alcoholic fatty liver disease.

Liver Int 2019 Aug 22. Epub 2019 Aug 22.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1111/liv.14225DOI Listing
August 2019

Multi-domain analysis of microvascular flow motion dynamics in NAFLD.

Microcirculation 2019 Jul 26;26(5):e12538. Epub 2019 Mar 26.

Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1111/micc.12538DOI Listing
July 2019

Relationship Between PNPLA3 rs738409 Polymorphism and Decreased Kidney Function in Children With NAFLD.

Hepatology 2019 Jul 17;70(1):142-153. Epub 2019 May 17.

Hepatology, Gastroenterology and Nutrition Unit, IRCCS "Bambino Gesù" Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.1002/hep.30625DOI Listing
July 2019

Association between Helicobacter pylori infection and risk of nonalcoholic fatty liver disease: An updated meta-analysis.

Metabolism 2019 Jul 29;96:56-65. Epub 2019 Apr 29.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.04.012DOI Listing
July 2019

Diagnosis and management of non-alcoholic fatty liver disease.

Postgrad Med J 2019 Jun 13;95(1124):314-322. Epub 2019 May 13.

The Institute of Developmental Sciences, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1136/postgradmedj-2018-136316DOI Listing
June 2019

Contribution of a genetic risk score to clinical prediction of hepatic steatosis in obese children and adolescents.

Dig Liver Dis 2019 Jun 26. Epub 2019 Jun 26.

Pediatric Diabetes and Metabolic Disorders Unit, Department of Surgery, Dentistry, Pediatrics and Gynaecology, University Hospital of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.05.029DOI Listing
June 2019

The evaluation of the repeatability of the C-ketoisocaproate breath test for assessing hepatic mitochondrial function.

Isotopes Environ Health Stud 2019 May 18;55(2):150-160. Epub 2019 Mar 18.

a National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust , Southampton , UK.

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http://dx.doi.org/10.1080/10256016.2019.1588265DOI Listing
May 2019

Association between non-alcoholic fatty liver disease and risk of atrial fibrillation in adult individuals: An updated meta-analysis.

Liver Int 2019 Apr 7;39(4):758-769. Epub 2019 Feb 7.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1111/liv.14044DOI Listing
April 2019

Letter: non-alcoholic fatty liver disease is associated with a history of osteoporotic fractures but not with low bone mineral density-authors' reply.

Aliment Pharmacol Ther 2019 Apr;49(7):961-962

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1111/apt.15181DOI Listing
April 2019

Does high LDL-cholesterol cause cardiovascular disease?

Expert Rev Clin Pharmacol 2019 02 26;12(2):91. Epub 2018 Dec 26.

c Nutrition and Metabolism, Faculty of Medicine , University of Southampton , Southampton , UK.

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https://www.tandfonline.com/doi/full/10.1080/17512433.2019.1
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http://dx.doi.org/10.1080/17512433.2019.1561100DOI Listing
February 2019

Systematic review with meta-analysis: non-alcoholic fatty liver disease is associated with a history of osteoporotic fractures but not with low bone mineral density.

Aliment Pharmacol Ther 2019 Feb 1;49(4):375-388. Epub 2019 Jan 1.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1111/apt.15087DOI Listing
February 2019

Omega-3 fatty acids and non-alcoholic fatty liver disease: Evidence of efficacy and mechanism of action.

Mol Aspects Med 2018 12 22;64:135-146. Epub 2018 Mar 22.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research, Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00982997183001
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http://dx.doi.org/10.1016/j.mam.2018.03.001DOI Listing
December 2018

Relationship between non-alcoholic steatohepatitis, PNPLA3 I148M genotype and bone mineral density in adolescents.

Liver Int 2018 12 25;38(12):2301-2308. Epub 2018 Sep 25.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1111/liv.13955DOI Listing
December 2018

Association of Plasma Ceramides With Myocardial Perfusion in Patients With Coronary Artery Disease Undergoing Stress Myocardial Perfusion Scintigraphy.

Arterioscler Thromb Vasc Biol 2018 12;38(12):2854-2861

From the Section of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Italy (A.M., G.T.).

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http://dx.doi.org/10.1161/ATVBAHA.118.311927DOI Listing
December 2018

Ad Libitum Mediterranean or Low-Fat Diets as Treatments for Nonalcoholic Fatty Liver Disease?

Hepatology 2018 11 11;68(5):1668-1671. Epub 2018 Oct 11.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/hep.30142DOI Listing
November 2018

Association between nonalcoholic fatty liver disease and colorectal tumours in asymptomatic adults undergoing screening colonoscopy: a systematic review and meta-analysis.

Metabolism 2018 10 20;87:1-12. Epub 2018 Jun 20.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2018.06.004DOI Listing
October 2018

Leukocyte extracellular vesicle concentration is inversely associated with liver fibrosis severity in NAFLD.

J Leukoc Biol 2018 09 30;104(3):631-639. Epub 2018 Mar 30.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/JLB.5A1217-501RDOI Listing
September 2018

Liver fat content, non-alcoholic fatty liver disease, and risk of ischaemic heart disease.

Eur Heart J 2018 09;39(36):3398

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Stefani 1, Verona, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehy237DOI Listing
September 2018

Association between plasma ceramides and inducible myocardial ischemia in patients with established or suspected coronary artery disease undergoing myocardial perfusion scintigraphy.

Metabolism 2018 08 16;85:305-312. Epub 2018 May 16.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2018.05.006DOI Listing
August 2018

Design and rationale of the INSYTE study: A randomised, placebo controlled study to test the efficacy of a synbiotic on liver fat, disease biomarkers and intestinal microbiota in non-alcoholic fatty liver disease.

Contemp Clin Trials 2018 08 19;71:113-123. Epub 2018 May 19.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service (NHS) Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1016/j.cct.2018.05.010DOI Listing
August 2018

Obesity and incidence of diabetes: Effect of absence of metabolic syndrome, insulin resistance, inflammation and fatty liver.

Atherosclerosis 2018 08 24;275:50-57. Epub 2018 May 24.

Endocrinology and Metabolism Unit, IDS Building, Southampton General Hospital, University of Southampton, MP 887, Southampton, UK; Southampton National Institute for Health Research, Biomedical Research Centre, Southampton General Hospital, Southampton, UK. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.05.042DOI Listing
August 2018

Nutritional Targeting of Cancer Cell Metabolism in Obesity.

J Nutr 2018 08;148(8):1207-1208

Nutrition and Metabolism, Human Development and Health, Faculty of Medicine, Southampton, United Kingdom.

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http://dx.doi.org/10.1093/jn/nxy142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075178PMC
August 2018

The characterisation of hepatic mitochondrial function in patients with non-alcoholic fatty liver disease (NAFLD) using the C-ketoisocaproate breath test.

J Breath Res 2018 07 19;12(4):046002. Epub 2018 Jul 19.

National Institute for Health Research, Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom. Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1088/1752-7163/aacf12DOI Listing
July 2018

Tests for diagnosing and monitoring non-alcoholic fatty liver disease in adults.

BMJ 2018 Jul 12;362:k2734. Epub 2018 Jul 12.

Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.

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http://www.bmj.com/lookup/doi/10.1136/bmj.k2734
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http://dx.doi.org/10.1136/bmj.k2734DOI Listing
July 2018

Liver zonation in children with non-alcoholic fatty liver disease: Associations with dietary fructose and uric acid concentrations.

Liver Int 2018 06 31;38(6):1102-1109. Epub 2018 Jan 31.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1111/liv.13661DOI Listing
June 2018

Resolution of fatty liver and weight loss: Independent associations with changes in serum lipids and apolipoproteins.

Atherosclerosis 2018 05 8;272:47-53. Epub 2018 Mar 8.

Endocrinology and Metabolism Unit, IDS Building, Southampton General Hospital, University of Southampton, Southampton, UK; Southampton National Institute for Health Research, Biomedical Research Centre, Southampton General Hospital, University of Southampton, Southampton, UK. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.03.018DOI Listing
May 2018

Reply to: "Energy drinks and adolescents - A hepatic health hazard?"

J Hepatol 2018 04 23;68(4):857-858. Epub 2017 Nov 23.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jhep.2017.11.021DOI Listing
April 2018

Non-alcoholic fatty liver disease: A risk factor for myocardial dysfunction?

J Hepatol 2018 04 10;68(4):640-642. Epub 2017 Dec 10.

Department of Medicine and Surgery, Università degli Studi di Milano Bicocca, Milan, Italy; Department of Medicine and Rehabilitation, Unit of Metabolic Medicine, Policlinico di Monza, Monza, Italy.

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http://dx.doi.org/10.1016/j.jhep.2017.12.002DOI Listing
April 2018

Nonalcoholic fatty liver disease increases risk of incident chronic kidney disease: A systematic review and meta-analysis.

Metabolism 2018 02 11;79:64-76. Epub 2017 Nov 11.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2017.11.003DOI Listing
February 2018

Nonalcoholic fatty liver disease and chronic vascular complications of diabetes mellitus.

Nat Rev Endocrinol 2018 02 29;14(2):99-114. Epub 2017 Dec 29.

Nutrition and Metabolism, Faculty of Medicine, Institute of Developmental Sciences (IDS), MP887, University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.1038/nrendo.2017.173DOI Listing
February 2018

Nonalcoholic Fatty Liver Disease and Risk of Incident Type 2 Diabetes: A Meta-analysis.

Diabetes Care 2018 02;41(2):372-382

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy

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http://dx.doi.org/10.2337/dc17-1902DOI Listing
February 2018

Nonalcoholic Fatty Liver Disease in Children.

Semin Liver Dis 2018 02 22;38(1):1-13. Epub 2018 Feb 22.

Hepatometabolic Disease Unit, Bambino Gesù Children's Hospital, IRCCS (Instituto di Ricovero e Cura a Carattere Scientifico), Rome, Italy.

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http://dx.doi.org/10.1055/s-0038-1627456DOI Listing
February 2018

Myocardial blood flow reserve is impaired in patients with aortic valve calcification and unobstructed epicardial coronary arteries.

Int J Cardiol 2017 Dec 15;248:427-432. Epub 2017 Jun 15.

Department of Cardiology, Sunshine Coast Hospital and Health Services, University of the Sunshine Coast and University of Queensland, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.06.023DOI Listing
December 2017

Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents.

J Hepatol 2017 05 14;66(5):1031-1036. Epub 2017 Feb 14.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jhep.2016.12.025DOI Listing
May 2017

Non-alcoholic fatty liver disease: an emerging driving force in chronic kidney disease.

Nat Rev Nephrol 2017 05 20;13(5):297-310. Epub 2017 Feb 20.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton.

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http://dx.doi.org/10.1038/nrneph.2017.16DOI Listing
May 2017

Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop.

J Nutr Sci 2017 8;6:e15. Epub 2017 May 8.

Department of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1017/jns.2017.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468740PMC
May 2017

The HDL cholesterol/apolipoprotein A-I ratio: an indicator of cardiovascular disease.

Curr Opin Endocrinol Diabetes Obes 2017 Apr;24(2):148-153

aDivision of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea bEndocrinology and Metabolism Unit, Southampton General Hospital, University of Southampton, Southampton, UK cDivision of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1097/MED.0000000000000315DOI Listing
April 2017

Extrahepatic Diseases and NAFLD: The Triangular Relationship between NAFLD, Type 2-Diabetes and Dysbiosis.

Dig Dis 2016;34 Suppl 1:11-8. Epub 2016 Aug 22.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1159/000447276DOI Listing
January 2017

Baseline and Change in Uric Acid Concentration Over Time Are Associated With Incident Hypertension in Large Korean Cohort.

Am J Hypertens 2017 Jan 24;30(1):42-50. Epub 2016 Aug 24.

Departments of Epidemiology and Medicine, and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1093/ajh/hpw091DOI Listing
January 2017

All cause mortality and body mass index in a young Asian occupational cohort without baseline metabolic syndrome components.

Int J Cardiol 2016 Dec 17;224:271-278. Epub 2016 Sep 17.

Nutrition and Metabolism Unit, IDS Building, Southampton General Hospital (University of Southampton), MP 887, Southampton, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.09.056DOI Listing
December 2016

Omega-3 fatty acids: Mechanisms of benefit and therapeutic effects in pediatric and adult NAFLD.

Crit Rev Clin Lab Sci 2016 14;53(2):106-20. Epub 2015 Oct 14.

d Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton , Southampton , UK , and.

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http://dx.doi.org/10.3109/10408363.2015.1092106DOI Listing
November 2016

Effect of exercise on the development of new fatty liver and the resolution of existing fatty liver.

J Hepatol 2016 10 30;65(4):791-797. Epub 2016 May 30.

Endocrinology and Metabolism Unit, IDS Building, Southampton General Hospital, (University of Southampton), MP 887 Southampton, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.05.026DOI Listing
October 2016

Insulin in Acute Coronary Syndrome: a Narrative Review with Contemporary Perspectives.

Cardiovasc Drugs Ther 2016 Oct;30(5):493-504

Department of Cardiology, Sunshine Coast Hospital and Health Services, University of the Sunshine Coast and University of Queensland, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1007/s10557-016-6679-9DOI Listing
October 2016

Non-alcoholic fatty liver disease and risk of incident cardiovascular disease: A meta-analysis.

J Hepatol 2016 09 17;65(3):589-600. Epub 2016 May 17.

WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Section of Psychiatry, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1016/j.jhep.2016.05.013DOI Listing
September 2016

Urine Albumin/Creatinine Ratio Below 30 mg/g is a Predictor of Incident Hypertension and Cardiovascular Mortality.

J Am Heart Assoc 2016 09 13;5(9). Epub 2016 Sep 13.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton and University Hospitals Southampton, UK Southampton National Institute for Health Research, Biomedical Research Centre, University Hospital Southampton, Southampton, UK

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http://dx.doi.org/10.1161/JAHA.116.003245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079007PMC
September 2016

Nonalcoholic fatty liver disease, cardiovascular outcomes, and mortality in patients undergoing a coronary angiogram.

Hepatology 2016 08 19;64(2):684-5. Epub 2016 Feb 19.

Nutrition and Metabolism Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/hep.28306DOI Listing
August 2016

Obesity: Metabolically healthy obesity and NAFLD.

Nat Rev Gastroenterol Hepatol 2016 08 29;13(8):442-4. Epub 2016 Jun 29.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton; and Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton, Tremona Road, Southampton SO166YD, UK.

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http://dx.doi.org/10.1038/nrgastro.2016.104DOI Listing
August 2016

Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH.

Biochim Biophys Acta 2016 Jul 23;1861(7):584-93. Epub 2016 Apr 23.

Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1016/j.bbalip.2016.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874946PMC
July 2016

Higher body fat percentage is associated with enhanced temperature perception in NAFLD: results from the randomised Wessex Evaluation of fatty Liver and Cardiovascular markers in NAFLD with OMacor thErapy trial (WELCOME) trial.

Diabetologia 2016 07 22;59(7):1422-1429. Epub 2016 Apr 22.

Human Development and Health Academic Unit, Faculty of Medicine, The Institute of Developmental Sciences (IDS), MP887, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.

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http://dx.doi.org/10.1007/s00125-016-3966-8DOI Listing
July 2016

Insulin-induced hypoglycaemia and the detection of myocardial injury using an ultrasensitive troponin assay.

Int J Cardiol 2016 Jul 10;215:446-8. Epub 2016 Apr 10.

Department of Cardiology, Sunshine Coast Hospital and Health Services, University of Sunshine Coast, University of Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.03.238DOI Listing
July 2016

Type 2 diabetes and risk of hospital admission or death for chronic liver diseases.

J Hepatol 2016 06 23;64(6):1358-64. Epub 2016 Jan 23.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, UK.

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http://dx.doi.org/10.1016/j.jhep.2016.01.014DOI Listing
June 2016

Fatty Liver, Insulin Resistance, and Obesity: Relationships With Increase in Coronary Artery Calcium Over Time.

Clin Cardiol 2016 Jun 21;39(6):321-8. Epub 2016 Mar 21.

Nutrition and Metabolism Unit, Southampton General Hospital (University of Southampton) and Southampton National Institute for Health Research Biomedical Research Centre, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/clc.22529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490777PMC
June 2016

EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease: is universal screening appropriate?

Diabetologia 2016 06 7;59(6):1141-4. Epub 2016 Apr 7.

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1007/s00125-016-3910-yDOI Listing
June 2016

Body mass index and mortality: understanding the patterns and paradoxes.

BMJ 2016 05 4;353:i2433. Epub 2016 May 4.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, UK NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK.

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http://dx.doi.org/10.1136/bmj.i2433DOI Listing
May 2016

Improvement in non-alcoholic fatty liver disease severity is associated with a reduction in carotid intima-media thickness progression.

Atherosclerosis 2016 Mar 24;246:13-20. Epub 2015 Dec 24.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.12.028DOI Listing
March 2016

Bidirectional Relationships and Disconnects between NAFLD and Features of the Metabolic Syndrome.

Int J Mol Sci 2016 Mar 11;17(3):367. Epub 2016 Mar 11.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Tremona Road, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.3390/ijms17030367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813227PMC
March 2016

Nonalcoholic Fatty Liver Disease Is Associated With Higher 1-year All-Cause Rehospitalization Rates in Patients Admitted for Acute Heart Failure.

Medicine (Baltimore) 2016 Feb;95(7):e2760

From the Division of General Medicine "Sacro Cuore" Hospital, Negrar, VR, Italy (FV, CG, LS, GA); Division of Cardiology, "Sacro Cuore" Hospital, Negrar, VR, Italy (SB, AC); Section of Cardiology, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy (AR); Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy (GZ, GT); Internal Medicine and Outpatient Liver Clinic, NOCSAE Baggiovara, Azienda USL di Modena, Modena, Italy (AL); Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, UK (CDB); and NIHR Biomedical Research Centre, University of Southampton (CDB), Southampton, UK.

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http://dx.doi.org/10.1097/MD.0000000000002760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998619PMC
February 2016

Change in fatty liver status and 5-year risk of incident metabolic syndrome: a retrospective cohort study.

Clin Hypertens 2015 17;21:22. Epub 2015 Nov 17.

Division of Cardiology, Department of Medicine, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1186/s40885-015-0032-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750798PMC
February 2016

Time to Replace Assessment of Liver Histology With MR-Based Imaging Tests to Assess Efficacy of Interventions for Nonalcoholic Fatty Liver Disease.

Gastroenterology 2016 Jan 18;150(1):7-10. Epub 2015 Nov 18.

University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1053/j.gastro.2015.11.016DOI Listing
January 2016

Application of new guidelines for the primary prevention of atherosclerotic cardiovascular disease in a Korean population.

J Atheroscler Thromb 2015 4;22(3):293-303. Epub 2014 Oct 4.

Department of Internal Medicine, Gangnam CHA Medical Center, CHA University, School of Medicine.

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http://dx.doi.org/10.5551/jat.26682DOI Listing
December 2015

Treating liver fat and serum triglyceride levels in NAFLD, effects of PNPLA3 and TM6SF2 genotypes: Results from the WELCOME trial.

J Hepatol 2015 Dec 10;63(6):1476-83. Epub 2015 Aug 10.

Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK; National Institute for Health Research Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1016/j.jhep.2015.07.036DOI Listing
December 2015

Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups.

Dig Liver Dis 2015 Dec 14;47(12):997-1006. Epub 2015 Aug 14.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Verona and Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.

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http://dx.doi.org/10.1016/j.dld.2015.08.004DOI Listing
December 2015

Circulating Markers of Liver Function and Cardiovascular Disease Risk.

Arterioscler Thromb Vasc Biol 2015 Nov 14;35(11):2290-6. Epub 2015 May 14.

From the Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy (G.T.); Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, United Kingdom (C.D.B.); and Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton, United Kingdom (C.D.B.).

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http://atvb.ahajournals.org/content/early/2015/05/14/ATVBAHA
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http://dx.doi.org/10.1161/ATVBAHA.115.305235DOI Listing
November 2015

Composition of dietary macronutrient intake is not associated with prevalence of coronary artery calcification in healthy Korean adults.

Ann Nutr Metab 2015 13;66(1):36-43. Epub 2014 Dec 13.

Division of Cardiology, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1159/000369563DOI Listing
October 2015

Gallstone Disease and Increased Risk of Ischemic Heart Disease: Causal Association or Epiphenomenon?

Arterioscler Thromb Vasc Biol 2015 Oct;35(10):2073-5

From the Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy (G.T.); Nutrition and Metabolism, Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK (C.D.B.); and Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton, UK (C.D.B.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306339DOI Listing
October 2015

Mulberry extract to modULate Blood glucosE Responses in noRmoglYcaemic adults (MULBERRY): study protocol for a randomised controlled trial.

Trials 2015 Oct 28;16:486. Epub 2015 Oct 28.

Primary Care & Population Sciences, Faculty of Medicine, University of Southampton, Aldermoor Health Centre, Southampton, SO16 5ST, UK.

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http://dx.doi.org/10.1186/s13063-015-0997-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625742PMC
October 2015

γ-Glutamyl Transferase Is Associated with Mortality Outcomes Independently of Fatty Liver.

Clin Chem 2015 Sep 7;61(9):1173-81. Epub 2015 Jul 7.

Nutrition and Metabolism Unit and Southampton National Institute for Health Research Biomedical Research Centre, Southampton General Hospital, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1373/clinchem.2015.240424DOI Listing
September 2015

A Perspective on Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.

Metab Syndr Relat Disord 2015 Aug 25;13(6):235-8. Epub 2015 Feb 25.

2 Nutrition and Metabolism, Faculty of Medicine, University of Southampton , Southampton, United Kingdom .

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http://dx.doi.org/10.1089/met.2015.1502DOI Listing
August 2015

Heart valve calcification in patients with type 2 diabetes and nonalcoholic fatty liver disease.

Metabolism 2015 Aug 1;64(8):879-87. Epub 2015 May 1.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2015.04.003DOI Listing
August 2015

Importance of early recognition of heterozygous familial hypercholesterolaemia.

Curr Opin Lipidol 2015 Aug;26(4):298-303

aLaboratory Medicine, University Hospital Southampton NHS Foundation Trust bFaculty of Medicine, Nutrition and Metabolism, Human Development and Health, Southampton NIHR Biomedical Research Centre, University Hospital Southampton, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1097/MOL.0000000000000196DOI Listing
August 2015

Increased Cardiovascular Mortality in Subjects With Metabolic Syndrome Is Largely Attributable to Diabetes and Hypertension in 159,971 Korean Adults.

J Clin Endocrinol Metab 2015 Jul 20;100(7):2606-12. Epub 2015 May 20.

Department of Cardiology (K.-C.S., B.-J.K., B.-S.K.), Department of Endocrinology and Metabolism (E.-J.R., W.-Y.L., K.-W.O., S.-W.P.), Department of Occupational and Environmental Medicine (S.R.), Department of Neurology (P.W.-C.), and Department of Nephrology (H.K., K.-B.L.), Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea; and Human Development and Health Academic Unit (C.D.B.), Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1210/jc.2014-4031DOI Listing
July 2015

All-Cause and Cardiovascular Mortality Among Koreans: Effects of Obesity and Metabolic Health.

Am J Prev Med 2015 Jul;49(1):62-71

Nutrition and Metabolism Unit, IDS Building, Southampton General Hospital (University of Southampton) and Southampton National Institute for Health Research Biomedical Research Centre, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.amepre.2015.02.010DOI Listing
July 2015

Daily energy expenditure, cardiorespiratory fitness and glycaemic control in people with type 1 diabetes.

PLoS One 2014 14;9(5):e97534. Epub 2014 May 14.

Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097534PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020853PMC
June 2015

An increased high-density lipoprotein cholesterol/apolipoprotein A-I ratio is associated with increased cardiovascular and all-cause mortality.

Heart 2015 Apr 30;101(7):553-8. Epub 2015 Jan 30.

Nutrition and Metabolism Unit, Southampton General Hospital, (University of Southampton) and Southampton National Institute for Health Research Biomedical Research Centre, Southampton, UK.

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http://dx.doi.org/10.1136/heartjnl-2014-306784DOI Listing
April 2015

NAFLD: a multisystem disease.

J Hepatol 2015 Apr;62(1 Suppl):S47-64

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1016/j.jhep.2014.12.012DOI Listing
April 2015

CKD and nonalcoholic fatty liver disease.

Am J Kidney Dis 2014 Oct 30;64(4):638-52. Epub 2014 Jul 30.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; Southampton National Institute for Health Research Biomedical Research Centre, Southampton, United Kingdom.

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http://dx.doi.org/10.1053/j.ajkd.2014.05.019DOI Listing
October 2014

The reduced cost of providing a nationally recognised service for familial hypercholesterolaemia.

Open Heart 2014 12;1(1):e000015. Epub 2014 Aug 12.

Southampton National Institute for Health Research, Biomedical Research Centre, University Hospital Southampton and University of Southampton , Southampton , UK.

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http://dx.doi.org/10.1136/openhrt-2013-000015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189221PMC
October 2014

Lower 25-hydroxyvitamin D3 levels and increased risk of liver diseases: is there a causal link?

Endocrine 2014 Sep 5;47(1):3-4. Epub 2014 Mar 5.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale A. Stefani 1, 37126, Verona, Italy,

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http://dx.doi.org/10.1007/s12020-014-0220-3DOI Listing
September 2014

Nonalcoholic fatty liver disease is independently associated with an increased incidence of chronic kidney disease in patients with type 1 diabetes.

Diabetes Care 2014 Jun 2;37(6):1729-36. Epub 2014 Apr 2.

Section of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Verona, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

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http://dx.doi.org/10.2337/dc13-2704DOI Listing
June 2014

Ectopic fat, insulin resistance, and nonalcoholic fatty liver disease: implications for cardiovascular disease.

Arterioscler Thromb Vasc Biol 2014 Jun 17;34(6):1155-61. Epub 2014 Apr 17.

From Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, United Kingdom (C.D.B.); Southampton National Institute for Health Research Biomedical Research Centre, University Hospital Southampton, Southampton, United Kingdom (C.D.B.); and Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy (G.T.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303034DOI Listing
June 2014

Towards a personalised diagnosis of type 2 diabetes.

Lancet Diabetes Endocrinol 2013 Sep 21;1(1):6-7. Epub 2013 Feb 21.

Nutrition and Metabolism, Faculty of Medicine, University of Southampton, Southampton, UK; Southampton National Institute for Health Research Biomedical Research Centre, Southampton, UK.

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http://dx.doi.org/10.1016/S2213-8587(13)70010-XDOI Listing
September 2013