Publications by authors named "Christopher Bot"

11Publications

Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.

J Cell Sci 2017 03 6;130(6):1134-1146. Epub 2017 Feb 6.

Karolinska Institutet, Department of Cell and Molecular Biology, Stockholm 171 77, Sweden

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http://dx.doi.org/10.1242/jcs.197236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358341PMC
March 2017

Evaluating 5-nitrofurans as trypanocidal agents.

Antimicrob Agents Chemother 2013 Apr 18;57(4):1638-47. Epub 2013 Jan 18.

Queen Mary Pre-Clinical Drug Discovery Group, School of Biological and Chemical Sciences, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1128/AAC.02046-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623332PMC
April 2013

Centromere-associated repeat arrays on Trypanosoma brucei chromosomes are much more extensive than predicted.

BMC Genomics 2012 Jan 18;13:29. Epub 2012 Jan 18.

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1186/1471-2164-13-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292466PMC
January 2012

Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs.

Bioorg Med Chem Lett 2011 Jul 7;21(13):3986-91. Epub 2011 May 7.

Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.bmcl.2011.05.009DOI Listing
July 2011

Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives.

Curr Top Med Chem 2011 ;11(16):2072-84

Queen Mary Pre-Clinical Drug Discovery Group, School of Biological and Chemical Sciences, Queen Mary University of London, UK.

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http://dx.doi.org/10.2174/156802611796575894DOI Listing
December 2011

Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.

J Biol Chem 2011 Apr 23;286(15):13088-95. Epub 2011 Feb 23.

School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M111.230847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075655PMC
April 2011

Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei.

Nucleic Acids Res 2011 Feb 22;39(3):1023-33. Epub 2010 Sep 22.

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

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http://dx.doi.org/10.1093/nar/gkq839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035458PMC
February 2011

Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi.

Genome Biol 2007 ;8(3):R37

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

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http://dx.doi.org/10.1186/gb-2007-8-3-r37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868937PMC
June 2007