Publications by authors named "Christopher Benz"

99Publications

Discovery of internalizing antibodies to basal breast cancer cells.

Protein Eng Des Sel 2018 01;31(1):17-28

Department of Anesthesia and Perioperative Care, University of California, San Francisco Rm 3C-38, Zuckerberg San Francisco General Hospital and Trauma Center, 1001 Potrero Ave, San Francisco, CA 94110, USA.

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http://dx.doi.org/10.1093/protein/gzx063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283401PMC
January 2018

Functional IGF1R variant predicts breast cancer risk in women with preeclampsia in California Teachers Study.

Cancer Causes Control 2017 Oct 18;28(10):1027-1032. Epub 2017 Aug 18.

Buck Institute for Research on Aging, Novato, CA, USA.

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http://dx.doi.org/10.1007/s10552-017-0942-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613056PMC
October 2017

Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.

Breast Cancer Res Treat 2017 Nov 4;166(2):593-601. Epub 2017 Aug 4.

Department of Biosciences and Nutrition, Karolinska Institutet, Hälsovägen 7, 141 83, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10549-017-4428-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668340PMC
November 2017

Comment on: 'Hypertensive diseases in pregnancy and breast cancer risk'.

Br J Cancer 2016 05 3;114(11):e10. Epub 2016 May 3.

Child Health and Development Studies of the Public Health Institute, Berkeley, CA 94709, USA.

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http://dx.doi.org/10.1038/bjc.2016.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891511PMC
May 2016

FOXM1 cistrome predicts breast cancer metastatic outcome better than FOXM1 expression levels or tumor proliferation index.

Breast Cancer Res Treat 2015 Nov 12;154(1):23-32. Epub 2015 Oct 12.

Buck Institute for Research on Aging, 8001 Redwood Blvd., Novato, CA, 94945, USA.

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http://dx.doi.org/10.1007/s10549-015-3589-7DOI Listing
November 2015

DGCR8 is essential for tumor progression following PTEN loss in the prostate.

EMBO Rep 2015 Sep 23;16(9):1219-32. Epub 2015 Jul 23.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California - San Francisco, San Francisco, CA, USA Center for Reproductive Sciences, University of California - San Francisco, San Francisco, CA, USA Department of Urology, University of California - San Francisco, San Francisco, CA, USA Department of Anatomic Pathology, University of California - San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.15252/embr.201439925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576988PMC
September 2015

mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms.

Breast Cancer Res Treat 2014 Apr 22;144(2):287-298. Epub 2014 Feb 22.

Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA,

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http://dx.doi.org/10.1007/s10549-014-2877-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318538PMC
April 2014

Age-related micro-RNA abundance in individual C. elegans.

Aging (Albany NY) 2013 Jun;5(6):394-411

Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824409PMC
http://dx.doi.org/10.18632/aging.100564DOI Listing
June 2013

FOXP3-positive regulatory T lymphocytes and epithelial FOXP3 expression in synchronous normal, ductal carcinoma in situ, and invasive cancer of the breast.

Breast Cancer Res Treat 2013 Jun 28;139(2):381-90. Epub 2013 May 28.

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1007/s10549-013-2556-4DOI Listing
June 2013

PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis.

Bioinformatics 2012 Sep;28(18):i640-i646

Department of Biomolecular Engineering and CBSE, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1093/bioinformatics/bts402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436829PMC
September 2012

Targeting Molecular Aberrations in Breast Cancer: Is It about Time?

Am Soc Clin Oncol Educ Book 2012 :186-91

From the Carol Franc Buck Breast Care Center, University of California, San Francisco; Cancer and Developmental Therapeutics Program, Buck Institute for Research on Aging, Novato, CA; Breast Cancer Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.14694/EdBook_AM.2012.32.186DOI Listing
April 2016

Young age, increased tumor proliferation and FOXM1 expression predict early metastatic relapse only for endocrine-dependent breast cancers.

Breast Cancer Res Treat 2011 Apr 12;126(3):803-10. Epub 2011 Jan 12.

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945, USA.

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http://link.springer.com/10.1007/s10549-011-1345-1
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http://dx.doi.org/10.1007/s10549-011-1345-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337964PMC
April 2011

Recent trends in hormone therapy utilization and breast cancer incidence rates in the high incidence population of Marin County, California.

BMC Public Health 2010 Apr 30;10:228. Epub 2010 Apr 30.

County of Marin, Department of Health and Human Services, 20 North San Pedro Road, San Rafael, CA 94903, USA.

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http://dx.doi.org/10.1186/1471-2458-10-228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876106PMC
April 2010

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

Cancer Res 2010 May 20;70(9):3709-17. Epub 2010 Apr 20.

Buck Institute for Age Research, Novato, California 94945, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862137PMC
May 2010

Development of a highly stable and targetable nanoliposomal formulation of topotecan.

J Control Release 2010 Jan 15;141(1):13-21. Epub 2009 Aug 15.

Hermes Biosciences, Inc., 61 Airport Boulevard, Suite D, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.1016/j.jconrel.2009.08.006DOI Listing
January 2010

Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression.

Clin Cancer Res 2009 May 21;15(9):3163-71. Epub 2009 Apr 21.

Department of Laboratory Medicine, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746548PMC
May 2009

Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis.

Cancer Res 2009 Feb 3;69(4):1279-83. Epub 2009 Feb 3.

Department of Pathology, Comprehensive Cancer Center, and National Foundation for Cancer Research, University of Alabama at Birmingham, Birmingham, Alabama 35294-0019, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754225PMC
February 2009

Unraveling the biologic and clinical complexities of HER2.

Clin Breast Cancer 2008 Oct;8(5):392-401

Comprehensive Cancer Center, University of California, San Francisco, CA 94115-1710, USA.

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http://dx.doi.org/10.3816/CBC.2008.n.047DOI Listing
October 2008

Ageing, oxidative stress and cancer: paradigms in parallax.

Nat Rev Cancer 2008 Nov;8(11):875-9

Christopher C. Benz and Christina Yau are at the Buck Institute for Age Research, Novato, California 94945, USA.

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http://dx.doi.org/10.1038/nrc2522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603471PMC
November 2008

Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users.

Cancer Epidemiol Biomarkers Prev 2008 May 7;17(5):1028-33. Epub 2008 May 7.

Department of Surgery, Kaiser Permanente Oakland Medical Center, Oakland, California, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0726DOI Listing
May 2008

Impact of aging on the biology of breast cancer.

Crit Rev Oncol Hematol 2008 Apr 18;66(1):65-74. Epub 2007 Oct 18.

Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA.

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http://dx.doi.org/10.1016/j.critrevonc.2007.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626623PMC
April 2008

Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells.

Mol Cancer Ther 2007 Oct;6(10):2737-46

Department of Anesthesia, University of California at San Francisco, Room 3C38, 1001 Potrero Avenue, San Francisco, CA 94110, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-07-0140DOI Listing
October 2007

Anti-oncomir suppression of tumor phenotypes.

Mol Interv 2007 Aug;7(4):199-202, 180

Department of Medicine, University of California, San Francisco, CA 94143, USA.

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http://mr.crossref.org/iPage?doi=10.1124%2Fmi.7.4.6
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http://dx.doi.org/10.1124/mi.7.4.6DOI Listing
August 2007

Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer.

Mol Pharmacol 2007 Jun 28;71(6):1525-34. Epub 2007 Mar 28.

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.107.03
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http://dx.doi.org/10.1124/mol.107.034090DOI Listing
June 2007

Quantification of cysteine oxidation in human estrogen receptor by mass spectrometry.

Anal Chem 2007 Apr 21;79(8):3083-90. Epub 2007 Mar 21.

Buck Institute for Age Research, Novato, California 94945, USA.

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http://dx.doi.org/10.1021/ac062154oDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536661PMC
April 2007

Novel pathways associated with quinone-induced stress in breast cancer cells.

Drug Metab Rev 2006 ;38(4):601-13

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, Novato, CA 94945, USA.

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http://www.tandfonline.com/doi/full/10.1080/0360253060095939
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http://dx.doi.org/10.1080/03602530600959391DOI Listing
January 2007

Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b.

J Biol Chem 2007 Jan 16;282(2):1479-86. Epub 2006 Nov 16.

Buck Institute for Age Research, Novato, California 94945, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M609383200
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http://dx.doi.org/10.1074/jbc.M609383200DOI Listing
January 2007

Type and duration of exogenous hormone use affects breast cancer histology.

Ann Surg Oncol 2007 Feb 14;14(2):695-703. Epub 2006 Nov 14.

Department of Surgery, Kaiser Permanente Oakland Medical Center, Oakland, California, 94602, USA.

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http://dx.doi.org/10.1245/s10434-006-9129-2DOI Listing
February 2007

Increased expression of urokinase-type plasminogen activator mRNA determines adverse prognosis in ErbB2-positive primary breast cancer.

J Clin Oncol 2006 Sep;24(26):4245-53

Swiss Institute for Experimental Cancer Research, National Center of Competence in Research, Molecular Oncology, Riehen, Switzerland.

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http://dx.doi.org/10.1200/JCO.2005.05.1912DOI Listing
September 2006

Breast cancer growth prevention by statins.

Cancer Res 2006 Sep;66(17):8707-14

Department of Surgery, University of California San Francisco/Mt. Zion Medical Center, Room C342, 1600 Divisadero, San Francisco, CA 94115, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-4061DOI Listing
September 2006

Validated high-throughput screening of drug-like small molecules for inhibitors of ErbB2 transcription.

Assay Drug Dev Technol 2006 Jun;4(3):273-84

Program of Cancer and Development Therapeutics, Buck Institute for Age Research, Novato, CA 94945, USA.

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http://dx.doi.org/10.1089/adt.2006.4.273DOI Listing
June 2006

Clinical trials are required to prove the chemopreventive worth of statins.

Arch Intern Med 2006 May;166(10):1143; author reply 1144

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http://dx.doi.org/10.1001/archinte.166.10.1143-aDOI Listing
May 2006

Rapid alteration of microRNA levels by histone deacetylase inhibition.

Cancer Res 2006 Feb;66(3):1277-81

Program of Cancer and Developmental Therapeutics, Buck Institute for Age Research, 8001 Redwood Boulevard, Novato, CA 94945, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3632DOI Listing
February 2006

Identification of an epithelial-specific enhancer regulating ESX expression.

Gene 2006 Feb 22;367:118-25. Epub 2005 Nov 22.

Cancer Research Institute, University of California San Francisco, Box 0808, San Francisco, CA 94143-0808, USA.

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http://dx.doi.org/10.1016/j.gene.2005.10.001DOI Listing
February 2006

Reactivity of zinc finger cysteines: chemical modifications within labile zinc fingers in estrogen receptor.

J Am Soc Mass Spectrom 2005 Dec 24;16(12):2017-26. Epub 2005 Oct 24.

Buck Institute for Age Research, Novato, CA 94945, USA.

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http://link.springer.com/10.1016/j.jasms.2005.08.009
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http://dx.doi.org/10.1016/j.jasms.2005.08.009DOI Listing
December 2005

Hyperplasia, reduced E-cadherin expression, and developmental arrest in mammary glands oxidatively stressed by loss of mitochondrial superoxide dismutase.

Breast 2005 Aug 19;14(4):256-63. Epub 2005 Apr 19.

Department of Anatomy, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.breast.2005.02.004DOI Listing
August 2005

Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation.

Mol Pharmacol 2005 Sep 6;68(3):606-15. Epub 2005 Jun 6.

Program of Cancer and Developmental Therapeutics, Buck Institute for Age Research, 8001 Red-wood Blvd., Novato, CA 94945, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.105.01
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http://dx.doi.org/10.1124/mol.105.013474DOI Listing
September 2005

Enhanced pharmacodynamic and antitumor properties of a histone deacetylase inhibitor encapsulated in liposomes or ErbB2-targeted immunoliposomes.

Clin Cancer Res 2005 May;11(9):3392-401

Hermes Biosciences, Inc., South San Francisco, Buck Institute for Age Research, Novato, California 94945, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-2445DOI Listing
May 2005

Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers.

Int J Biochem Cell Biol 2005 May;37(5):1130-44

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945, USA.

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http://dx.doi.org/10.1016/j.biocel.2004.09.006DOI Listing
May 2005

Future directions of liposome- and immunoliposome-based cancer therapeutics.

Semin Oncol 2004 Dec;31(6 Suppl 13):196-205

UCSF Comprehensive Cancer Center, San Francisco, CA 94115-1710, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2004.08.009DOI Listing
December 2004

Risk factors for estrogen receptor-positive breast cancer.

Arch Surg 2005 Jan;140(1):58-62

Department of Surgery, University of California, San Francisco, Cancer Center, 94115, USA.

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http://dx.doi.org/10.1001/archsurg.140.1.58DOI Listing
January 2005

Development of ligand-targeted liposomes for cancer therapy.

Expert Opin Ther Targets 2004 Aug;8(4):335-53

University of California at San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1517/14728222.8.4.335DOI Listing
August 2004

Geographic excess of estrogen receptor-positive breast cancer.

Cancer Epidemiol Biomarkers Prev 2003 Dec;12(12):1523-7

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, Novato, California 94945, USA.

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December 2003

Essential cysteine-alkylation strategies to monitor structurally altered estrogen receptor as found in oxidant-stressed breast cancers.

Anal Biochem 2003 Sep;320(1):21-31

Buck Institute for Age Research (Program of Cancer and Developmental Therapeutics), Novato, CA 94945, USA.

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http://dx.doi.org/10.1016/s0003-2697(03)00296-3DOI Listing
September 2003

Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen.

Mol Cancer Ther 2002 Apr;1(6):385-92

Program of Cancer and Development Therapeutics, Buck Institute for Age Research, Novato, California 94945, USA.

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April 2002

Age-dependent changes in breast cancer hormone receptors and oxidant stress markers.

Breast Cancer Res Treat 2002 Dec;76(3):221-36

Comprehensive Cancer Center, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1023/a:1020886801674DOI Listing
December 2002

Age-associated biomarker profiles of human breast cancer.

Int J Biochem Cell Biol 2002 Nov;34(11):1318-30

Stiftung Tumorbank Basel and Department of Research, University Clinics, Basel, Switzerland.

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http://dx.doi.org/10.1016/s1357-2725(02)00052-3DOI Listing
November 2002

Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis.

Biochim Biophys Acta 2002 Aug;1591(1-3):109-118

Department of Anesthesia and Pharmaceutical Chemistry, University of California-San Francisco, SF General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA.

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http://dx.doi.org/10.1016/s0167-4889(02)00256-2DOI Listing
August 2002