Publications

Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.
Alcohol Clin Exp Res 2015 Oct 2;39(10):1917-29. Epub 2015 Sep 2.
Center for Sleep & Circadian Biology, Department of Neurobiology, Northwestern University, Evanston, Illinois.

Circadian rhythms, alcohol and gut interactions.
Alcohol 2015 Jun 14;49(4):389-98. Epub 2014 Nov 14.
Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA; Department of Pharmacology, Rush University Medical Center, Chicago, IL, USA; Department of Molecular Biophysics & Physiology, Rush University Medical Center, Chicago, IL, USA; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

HIV-associated mucosal gene expression: region-specific alterations.
AIDS 2015 Mar;29(5):537-46
aDepartment of Internal Medicine, Division of Gastroenterology, Hepatology, and Nutrition bDepartment of Pharmacology cDepartment of Physiology, Rush University Medical Center, Chicago, Illinois dDivision of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands eDepartment of Immunology/Microbiology, Rush University Medical Center, Chicago, Illinois, USA fDepartment of Biochemistry, Rush University Medical Center gRuth M. Rothstein CORE Center/Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois, USA.

Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: use of time course analysis to optimize its use to assess regional gut permeability.
Clin Chim Acta 2015 Mar 12;442:24-32. Epub 2015 Jan 12.
Department of Internal Medicine, Section of Gastroenterology, Rush University Medical Center, Chicago, IL, United States; Department of Pharmacology, Rush University, Chicago, IL, United States; Department of Molecular Biophysics and Physiology, Rush University, Chicago, IL, United States; F.C. Donders Chair, Faculty of Science, University of Utrecht, Utrecht, The Netherlands. Electronic address:

In vitro evaluation of intestinal epithelial TLR activation in preventing food allergic responses.
Clin Immunol 2014 Oct 21;154(2):91-9. Epub 2014 Jul 21.
Department of Immunology/Microbiology, Rush University Medical Center, Chicago, IL, USA; Division of Pharmacology, Utrecht Institute Pharmaceutical Sciences, Faculty of Science, Utrecht University, The Netherlands.

Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice.
Part Fibre Toxicol 2011 Jun 9;8:19. Epub 2011 Jun 9.
Department of Medicine, Section of Gastroenterology and Nutrition Rush University Medical College, 1725 W Harrison Street, Chicago, IL 60612, USA.

Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats.
J Hepatol 2009 Mar 29;50(3):538-47. Epub 2008 Dec 29.
Department of Internal Medicine, Division of Digestive Disease and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA.

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease.
PLoS One 2011 1;6(12):e28032. Epub 2011 Dec 1.
Department of Internal Medicine, Section of Gastroenterology, Rush University Medical Center, Chicago, Illinois, United States of America.

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation.
PLoS One 2013 18;8(6):e67102. Epub 2013 Jun 18.
Center for Sleep and Circadian Biology, Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America ; Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

Circadian disorganization alters intestinal microbiota.
PLoS One 2014 21;9(5):e97500. Epub 2014 May 21.
Department of Internal Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, Illinois, United States of America; Department of Pharmacology, Rush University Medical Center, Chicago, Illinois, United States of America; Department of Physiology, Rush University Medical Center, Chicago, Illinois, United States of America; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.

Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness.
Redox Biol 2014 19;3:40-6. Epub 2014 Oct 19.
Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA; Department of Pharmacology, Rush University Medical Center, Chicago, IL, USA; Department of Molecular Biophysics & Physiology, Rush University Medical Center, Chicago, IL, USA; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Alcohol induced alterations to the human fecal VOC metabolome.
PLoS One 2015 9;10(3):e0119362. Epub 2015 Mar 9.
Department of Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, Illinois, United States of America; Department of Pharmacology, Rush University Medical Center, Chicago, Illinois, United States of America; Department of Molecular Biophysics and Physiology, Rush University Medical Center, Chicago, Illinois, United States of America; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Alcohol and Gut-Derived Inflammation.
Alcohol Res 2017 ;38(2):163-171
Faraz Bishehsari, M.D., Ph.D., is an Assistant Professor; Garth Swanson, M.D., is an Assistant Professor; Vishal Desai, M.D., is a Physician; Robin M. Voigt, Ph.D., is an Assistant Professor; Christopher B. Forsyth, Ph.D., is an Associate Professor; and Ali Keshavarzian, M.D., is a Professor, all in the Department of Internal Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, Illinois. Emmeline Magno, M.D., is an Internist in the Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois.

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