Christopher A Maxwell

Christopher A Maxwell

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Christopher A Maxwell

Christopher A Maxwell

Publications by authors named "Christopher A Maxwell"

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FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.

EMBO Rep 2019 Jul 24:e47495. Epub 2019 Jul 24.

Medical Research Council, Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK.

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http://dx.doi.org/10.15252/embr.201847495DOI Listing
July 2019

Hyaluronan-binding by CD44 reduces the memory potential of activated murine CD8 T cells.

Eur J Immunol 2018 05 19;48(5):803-814. Epub 2018 Jan 19.

Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/eji.201747263DOI Listing
May 2018

The non-motor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation.

Mol Biol Cell 2018 Jan 31. Epub 2018 Jan 31.

Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada V5Z 4H4

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http://dx.doi.org/10.1091/mbc.E17-08-0531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905292PMC
January 2018

Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2.

Cell Cycle 2014 29;13(14):2248-61. Epub 2014 May 29.

Department of Pediatrics; Child and Family Research Institute; University of British Columbia; Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.4161/cc.29270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111680PMC
December 2015

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.

Authors:
Ignacio Blanco Karoline Kuchenbaecker Daniel Cuadras Xianshu Wang Daniel Barrowdale Gorka Ruiz de Garibay Pablo Librado Alejandro Sánchez-Gracia Julio Rozas Núria Bonifaci Lesley McGuffog Vernon S Pankratz Abul Islam Francesca Mateo Antoni Berenguer Anna Petit Isabel Català Joan Brunet Lidia Feliubadaló Eva Tornero Javier Benítez Ana Osorio Teresa Ramón y Cajal Heli Nevanlinna Kristiina Aittomäki Banu K Arun Amanda E Toland Beth Y Karlan Christine Walsh Jenny Lester Mark H Greene Phuong L Mai Robert L Nussbaum Irene L Andrulis Susan M Domchek Katherine L Nathanson Timothy R Rebbeck Rosa B Barkardottir Anna Jakubowska Jan Lubinski Katarzyna Durda Katarzyna Jaworska-Bieniek Kathleen Claes Tom Van Maerken Orland Díez Thomas V Hansen Lars Jønson Anne-Marie Gerdes Bent Ejlertsen Miguel de la Hoya Trinidad Caldés Alison M Dunning Clare Oliver Elena Fineberg Margaret Cook Susan Peock Emma McCann Alex Murray Chris Jacobs Gabriella Pichert Fiona Lalloo Carol Chu Huw Dorkins Joan Paterson Kai-Ren Ong Manuel R Teixeira Frans B L Hogervorst Annemarie H van der Hout Caroline Seynaeve Rob B van der Luijt Marjolijn J L Ligtenberg Peter Devilee Juul T Wijnen Matti A Rookus Hanne E J Meijers-Heijboer Marinus J Blok Ans M W van den Ouweland Cora M Aalfs Gustavo C Rodriguez Kelly-Anne A Phillips Marion Piedmonte Stacy R Nerenstone Victoria L Bae-Jump David M O'Malley Elena S Ratner Rita K Schmutzler Barbara Wappenschmidt Kerstin Rhiem Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Hansjoerg J Plendl Dieter Niederacher Christian Sutter Shan Wang-Gohrke Doris Steinemann Sabine Preisler-Adams Karin Kast Raymonda Varon-Mateeva Andrea Gehrig Anders Bojesen Inge Sokilde Pedersen Lone Sunde Uffe Birk Jensen Mads Thomassen Torben A Kruse Lenka Foretova Paolo Peterlongo Loris Bernard Bernard Peissel Giulietta Scuvera Siranoush Manoukian Paolo Radice Laura Ottini Marco Montagna Simona Agata Christine Maugard Jacques Simard Penny Soucy Andreas Berger Anneliese Fink-Retter Christian F Singer Christine Rappaport Daphne Geschwantler-Kaulich Muy-Kheng Tea Georg Pfeiler Esther M John Alex Miron Susan L Neuhausen Mary Beth Terry Wendy K Chung Mary B Daly David E Goldgar Ramunas Janavicius Cecilia M Dorfling Elisabeth J van Rensburg Florentia Fostira Irene Konstantopoulou Judy Garber Andrew K Godwin Edith Olah Steven A Narod Gad Rennert Shani Shimon Paluch Yael Laitman Eitan Friedman Annelie Liljegren Johanna Rantala Marie Stenmark-Askmalm Niklas Loman Evgeny N Imyanitov Ute Hamann Amanda B Spurdle Sue Healey Jeffrey N Weitzel Josef Herzog David Margileth Chiara Gorrini Manel Esteller Antonio Gómez Sergi Sayols Enrique Vidal Holger Heyn Dominique Stoppa-Lyonnet Melanie Léoné Laure Barjhoux Marion Fassy-Colcombet Antoine de Pauw Christine Lasset Sandra Fert Ferrer Laurent Castera Pascaline Berthet François Cornelis Yves-Jean Bignon Francesca Damiola Sylvie Mazoyer Olga M Sinilnikova Christopher A Maxwell Joseph Vijai Mark Robson Noah Kauff Marina J Corines Danylko Villano Julie Cunningham Adam Lee Noralane Lindor Conxi Lázaro Douglas F Easton Kenneth Offit Georgia Chenevix-Trench Fergus J Couch Antonis C Antoniou Miguel Angel Pujana

PLoS One 2015 1;10(4):e0120020. Epub 2015 Apr 1.

Breast Cancer and Systems Biology Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120020PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382299PMC
December 2015

Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.

J Pathol 2014 Jul 29;233(3):247-57. Epub 2014 Apr 29.

Institute of Neuropathology, University Hospital Bellvitge, University of Barcelona, Bellvitge Institute for Biomedical Research (IDIBELL), CIBERNED, L'Hospitalet del Llobregat, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/path.4343DOI Listing
July 2014

The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells.

PLoS One 2013 3;8(9):e73548. Epub 2013 Sep 3.

Department of Pediatrics, Child & Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073548PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760809PMC
May 2014

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

Authors:
Christopher A Maxwell Javier Benítez Laia Gómez-Baldó Ana Osorio Núria Bonifaci Ricardo Fernández-Ramires Sylvain V Costes Elisabet Guinó Helen Chen Gareth J R Evans Pooja Mohan Isabel Català Anna Petit Helena Aguilar Alberto Villanueva Alvaro Aytes Jordi Serra-Musach Gad Rennert Flavio Lejbkowicz Paolo Peterlongo Siranoush Manoukian Bernard Peissel Carla B Ripamonti Bernardo Bonanni Alessandra Viel Anna Allavena Loris Bernard Paolo Radice Eitan Friedman Bella Kaufman Yael Laitman Maya Dubrovsky Roni Milgrom Anna Jakubowska Cezary Cybulski Bohdan Gorski Katarzyna Jaworska Katarzyna Durda Grzegorz Sukiennicki Jan Lubiński Yin Yao Shugart Susan M Domchek Richard Letrero Barbara L Weber Frans B L Hogervorst Matti A Rookus J Margriet Collee Peter Devilee Marjolijn J Ligtenberg Rob B van der Luijt Cora M Aalfs Quinten Waisfisz Juul Wijnen Cornelis E P van Roozendaal Douglas F Easton Susan Peock Margaret Cook Clare Oliver Debra Frost Patricia Harrington D Gareth Evans Fiona Lalloo Rosalind Eeles Louise Izatt Carol Chu Diana Eccles Fiona Douglas Carole Brewer Heli Nevanlinna Tuomas Heikkinen Fergus J Couch Noralane M Lindor Xianshu Wang Andrew K Godwin Maria A Caligo Grazia Lombardi Niklas Loman Per Karlsson Hans Ehrencrona Anna von Wachenfeldt Rosa Bjork Barkardottir Ute Hamann Muhammad U Rashid Adriana Lasa Trinidad Caldés Raquel Andrés Michael Schmitt Volker Assmann Kristen Stevens Kenneth Offit João Curado Hagen Tilgner Roderic Guigó Gemma Aiza Joan Brunet Joan Castellsagué Griselda Martrat Ander Urruticoechea Ignacio Blanco Laima Tihomirova David E Goldgar Saundra Buys Esther M John Alexander Miron Melissa Southey Mary B Daly Rita K Schmutzler Barbara Wappenschmidt Alfons Meindl Norbert Arnold Helmut Deissler Raymonda Varon-Mateeva Christian Sutter Dieter Niederacher Evgeny Imyamitov Olga M Sinilnikova Dominique Stoppa-Lyonne Sylvie Mazoyer Carole Verny-Pierre Laurent Castera Antoine de Pauw Yves-Jean Bignon Nancy Uhrhammer Jean-Philippe Peyrat Philippe Vennin Sandra Fert Ferrer Marie-Agnès Collonge-Rame Isabelle Mortemousque Amanda B Spurdle Jonathan Beesley Xiaoqing Chen Sue Healey Mary Helen Barcellos-Hoff Marc Vidal Stephen B Gruber Conxi Lázaro Gabriel Capellá Lesley McGuffog Katherine L Nathanson Antonis C Antoniou Georgia Chenevix-Trench Markus C Fleisch Víctor Moreno Miguel Angel Pujana

PLoS Biol 2011 Nov 15;9(11):e1001199. Epub 2011 Nov 15.

Translational Research Laboratory, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute-IDIBELL, L'Hospitalet, Catalonia, Spain.

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http://dx.doi.org/10.1371/journal.pbio.1001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217025PMC
November 2011

Multifunctional proteins bridge mitosis with motility and cancer with inflammation and arthritis.

ScientificWorldJournal 2010 Jun 29;10:1244-57. Epub 2010 Jun 29.

Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1100/tsw.2010.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763930PMC
June 2010

The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma.

Br J Haematol 2008 Feb 10;140(3):295-302. Epub 2007 Dec 10.

Department of Oncology, University of Alberta/Cross Cancer Institute, Edmonton, AB, Canada.

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http://dx.doi.org/10.1111/j.1365-2141.2007.06913.xDOI Listing
February 2008

Targeting aurora kinases as therapy in multiple myeloma.

Blood 2007 May 9;109(9):3915-21. Epub 2007 Jan 9.

Division of Hematology, Veterans Administration West Los Angeles-UCLA Medical School and Jonsson Cancer Center, University of California-Los Angeles, CA, USA.

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http://dx.doi.org/10.1182/blood-2006-07-037671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874561PMC
May 2007

Intensity-based signal separation algorithm for accurate quantification of clustered centrosomes in tissue sections.

Microsc Res Tech 2006 Dec;69(12):964-72

Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1002/jemt.20372DOI Listing
December 2006

The pleiotropic roles of transforming growth factor beta in homeostasis and carcinogenesis of endocrine organs.

Endocr Relat Cancer 2006 Jun;13(2):379-400

Life Sciences Division, 1 Cyclotron Road, MS 977-225A, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1677/erc.1.01112DOI Listing
June 2006

A potential role for centrosomal deregulation within IgH translocation-positive myeloma.

Med Hypotheses 2005 ;65(5):915-21

Department of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1016/j.mehy.2005.05.031DOI Listing
October 2005

Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity.

Cancer Res 2005 Feb;65(3):850-60

Department of Oncology, University of Alberta and Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2.

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February 2005

Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.

Curr Drug Targets Cardiovasc Haematol Disord 2005 Feb;5(1):3-14

Department of Oncology, University of Alberta & Cross Cancer Institute, Edmonton, 11560 University Avenue, Edmonton, Alberta, Canada T6G 1Z2.

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February 2005

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.

Blood 2004 Aug 22;104(4):1151-8. Epub 2004 Apr 22.

Department of Medical Oncology, Cross Cancer Institute, 11560 University Ave, Edmonton, AB, T6G 1Z2, Canada.

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http://dx.doi.org/10.1182/blood-2003-11-4079DOI Listing
August 2004

Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications.

Cancer Res 2003 Oct;63(20):6689-96

Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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October 2003

RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability.

Mol Biol Cell 2003 Jun 20;14(6):2262-76. Epub 2003 Mar 20.

Department of Oncology, University of Alberta/Cross Cancer Institute, Edmonton Alberta Canada T6G 1Z2.

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http://dx.doi.org/10.1091/mbc.e02-07-0377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC194876PMC
June 2003

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression.

Blood 2003 Feb 3;101(4):1520-9. Epub 2002 Oct 3.

Department of Oncology, University of Alberta and Cross Cancer Institute, Edmonton, Canada.

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http://dx.doi.org/10.1182/blood-2002-06-1675DOI Listing
February 2003