Christopher A Loffredo

Christopher A Loffredo

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Christopher A Loffredo

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Somatic mutation signatures in primary liver tumors of workers exposed to ionizing radiation.

Sci Rep 2019 Dec 3;9(1):18199. Epub 2019 Dec 3.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.

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http://dx.doi.org/10.1038/s41598-019-54773-zDOI Listing
December 2019

Environmental ototoxicants, a potential new class of chemical stressors.

Environ Res 2019 04 26;171:378-394. Epub 2019 Jan 26.

Slovak Medical University, Faculty of Public Health, Department of Environmental Medicine, Limbova 12, 83303 Bratislava, Slovakia. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2019.01.042DOI Listing
April 2019

Body mass index modifies bladder cancer risk associated with low estrogen exposure among Egyptian women after menopause.

Cancer Causes Control 2019 Mar 21;30(3):249-258. Epub 2019 Jan 21.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.

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http://dx.doi.org/10.1007/s10552-019-1131-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690206PMC
March 2019

-ΔG is associated with prostate cancer among men at increased risk of sexually transmitted infections.

Commun Biol 2018 14;1:191. Epub 2018 Nov 14.

1Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD USA.

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http://dx.doi.org/10.1038/s42003-018-0193-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235841PMC
November 2018

Association of Anthropometric Measures with Prostate Cancer among African American Men in the NCI-Maryland Prostate Cancer Case-Control Study.

Cancer Epidemiol Biomarkers Prev 2018 08 21;27(8):936-944. Epub 2018 May 21.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072587PMC
August 2018

Familial co-occurrence of congenital heart defects follows distinct patterns.

Eur Heart J 2018 03;39(12):1015-1022

Wilhelm Johannsen Centre for Functional Genome Research, Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1093/eurheartj/ehx314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018923PMC
March 2018

Aspirin Use Reduces the Risk of Aggressive Prostate Cancer and Disease Recurrence in African-American Men.

Cancer Epidemiol Biomarkers Prev 2017 06 14;26(6):845-853. Epub 2017 Mar 14.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-1027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457351PMC
June 2017

Nonoccupational exposure to agricultural work and risk of urinary bladder cancer among Egyptian women.

Arch Environ Occup Health 2017 May 30;72(3):166-172. Epub 2016 Mar 30.

a Department of Epidemiology and Public Health , University of Maryland School of Medicine , Baltimore , Maryland , USA.

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http://dx.doi.org/10.1080/19338244.2016.1169155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865450PMC
May 2017

Changes in the diagnosis of congenital cardiovascular malformations during the 1st year of life: impacts on epidemiological risk factor associations.

Cardiol Young 2017 May;27(4):770-781

1Department of Biostatistics, Bioinformatics and Biomathematics,Georgetown University Medical Center,Washington,District of Columbia,United States of America.

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http://dx.doi.org/10.1017/S104795111600130XDOI Listing
May 2017

Metabolomic profiles of current cigarette smokers.

Mol Carcinog 2017 02 22;56(2):594-606. Epub 2016 Aug 22.

Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1002/mc.22519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646689PMC
February 2017

Menthol Smokers: Metabolomic Profiling and Smoking Behavior.

Cancer Epidemiol Biomarkers Prev 2017 01 14;26(1):51-60. Epub 2016 Sep 14.

Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386404PMC
January 2017

Parental perceptions of congenital cardiovascular malformations in their children.

Cardiol Young 2016 Aug 12;26(6):1158-67. Epub 2015 Nov 12.

5Georgetown University,Washington,District of Columbia,United States of America.

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http://dx.doi.org/10.1017/S104795111500253XDOI Listing
August 2016

Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling.

J Enzyme Inhib Med Chem 2015 ;30(5):786-95

a Department of Health Sciences , Biomedical Sciences Program, College of Arts and Sciences, Qatar University , Doha , Qatar .

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http://dx.doi.org/10.3109/14756366.2014.971781DOI Listing
May 2016

Simple reaction time in 8-9-year old children environmentally exposed to PCBs.

Neurotoxicology 2015 Dec 19;51:138-44. Epub 2015 Oct 19.

Department of Environmental Medicine, Slovak Medical University, Limbová 12, 83303 Bratislava, Slovakia. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2015.10.005DOI Listing
December 2015

Waterpipe Smoking And The DRD2/ANKK1 Genotype.

J Egypt Public Health Assoc 2010 ;85(3-4):131-48

Dept. of Public Health, Cairo University, Cairo, Egypt.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622212PMC
November 2015

Viral transmission risk factors in an Egyptian population with high hepatitis C prevalence.

BMC Public Health 2015 Oct 7;15:1030. Epub 2015 Oct 7.

Lombardi Cancer Center, Georgetown University, 3970 Reservoir Rd, Washington, DC, 20057, USA.

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http://dx.doi.org/10.1186/s12889-015-2369-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596377PMC
October 2015

Hepatitis C virus Genotype 1a core gene nucleotide patterns associated with hepatocellular carcinoma risk.

J Gen Virol 2015 Sep 3;96(9):2928-37. Epub 2015 Jul 3.

5​Department of Biostatistics, Georgetown University, Washington, DC 20057, USA 4​Department of Oncology, Georgetown University, Washington, DC 20057, USA.

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http://dx.doi.org/10.1099/jgv.0.000219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857454PMC
September 2015

Relationship of birth weight with congenital cardiovascular malformations in a population-based study.

Cardiol Young 2015 Aug 28;25(6):1086-92. Epub 2014 Aug 28.

1Lombardi Comprehensive Cancer Center,Georgetown University,Washington,District of Columbia,United States of America.

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http://dx.doi.org/10.1017/S1047951114001644DOI Listing
August 2015

Preventing hepatocellular carcinoma in Egypt: results of a Pilot Health Education Intervention Study.

BMC Res Notes 2015 Aug 29;8:384. Epub 2015 Aug 29.

Department of Oncology, Georgetown University, 3970 Reservoir Rd, Washington DC, 20057, USA.

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http://dx.doi.org/10.1186/s13104-015-1351-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553015PMC
August 2015

Biomarkers linking PCB exposure and obesity.

Curr Pharm Biotechnol 2014 ;15(11):1058-68

415 College Street, NW, Room 335, EE Just Hall, Washington DC-20059, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292903PMC
http://dx.doi.org/10.2174/1389201015666141122203509DOI Listing
July 2015

Telomere length variation: A potential new telomere biomarker for lung cancer risk.

Lung Cancer 2015 Jun 20;88(3):297-303. Epub 2015 Mar 20.

Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428929PMC
June 2015

Mediation analysis of gestational age, congenital heart defects, and infant birth-weight.

BMC Res Notes 2014 Dec 17;7:926. Epub 2014 Dec 17.

Departments of Oncology and of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, 3800 Reservoir Rd, NW, Washington, DC 20057, USA.

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http://dx.doi.org/10.1186/1756-0500-7-926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320577PMC
December 2014

Multiple pregnancies, hepatitis C, and risk for hepatocellular carcinoma in Egyptian women.

BMC Cancer 2014 Nov 29;14:893. Epub 2014 Nov 29.

Department of Epidemiology and Public Health, University of Maryland School of Medicine, 660 West Redwood Street, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1186/1471-2407-14-893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258798PMC
November 2014

Knowledge and perceptions of hepatitis C infection and pesticides use in two rural villages in Egypt.

BMC Public Health 2014 May 24;14:501. Epub 2014 May 24.

Lombardi Cancer Center, Georgetown University, 3970 Reservoir Rd, Washington, DC 20057, USA.

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http://dx.doi.org/10.1186/1471-2458-14-501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050414PMC
May 2014

Associations of depression and neuroticism with smoking behavior and motives among men in rural Qalyubia (Egypt).

J Egypt Public Health Assoc 2014 Apr;89(1):16-21

aPublic Health Department, Faculty of Medicine, Cairo University bThe National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt cLombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, DC dDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/01.EPX.0000444060.91661.6fDOI Listing
April 2014

Agricultural workers and urinary bladder cancer risk in Egypt.

Arch Environ Occup Health 2014 ;69(1):3-10

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1080/19338244.2012.719556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819117PMC
November 2013

A randomized, controlled community-wide intervention to reduce environmental tobacco smoke exposure.

Nicotine Tob Res 2013 Aug 17;15(8):1372-81. Epub 2013 Jan 17.

Department of Microbiology and Immunology, Georgetown University, Washington, DC 20057, USA.

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http://dx.doi.org/10.1093/ntr/nts333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715387PMC
August 2013

Knowledge and willingness to provide research biospecimens among foreign-born Latinos using safety-net clinics.

J Community Health 2013 Aug;38(4):652-9

Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20057, USA.

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http://dx.doi.org/10.1007/s10900-013-9660-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706511PMC
August 2013

Evaluation of midkine as a diagnostic serum biomarker in hepatocellular carcinoma.

Clin Cancer Res 2013 Jul 29;19(14):3944-54. Epub 2013 May 29.

Liver Cancer Institute and Zhongshan Hospital, Institutes of Biomedical Science, Department of Biostatistics, School of Public Health, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314491PMC
July 2013

Tobacco-specific nitrosamine exposures in smokers and nonsmokers exposed to cigarette or waterpipe tobacco smoke.

Nicotine Tob Res 2013 Jan 9;15(1):130-8. Epub 2012 May 9.

Department of Public Health, Cairo University, Cairo, Egypt.

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http://dx.doi.org/10.1093/ntr/nts099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524061PMC
January 2013

MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status.

PLoS One 2012 18;7(6):e39011. Epub 2012 Jun 18.

Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039011PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377597PMC
December 2012

Urinary bladder cancer risk factors in Egypt: a multicenter case-control study.

Cancer Epidemiol Biomarkers Prev 2012 Mar 6;21(3):537-46. Epub 2011 Dec 6.

Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297723PMC
March 2012

Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence.

Carcinogenesis 2012 Jan 9;33(1):113-8. Epub 2011 Nov 9.

Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA.

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http://dx.doi.org/10.1093/carcin/bgr248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276329PMC
January 2012

Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk.

Hum Mol Genet 2011 Jan 18;20(2):378-86. Epub 2010 Oct 18.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA.

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http://dx.doi.org/10.1093/hmg/ddq461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005901PMC
January 2011

A meta-analysis of the effectiveness of albendazole compared with metronidazole as treatments for infections with Giardia duodenalis.

PLoS Negl Trop Dis 2010 May 11;4(5):e682. Epub 2010 May 11.

Department of Biology, Georgetown University, Washington, D. C., United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0000682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867942PMC
May 2010

Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study.

Carcinogenesis 2010 Apr 28;31(4):654-9. Epub 2010 Jan 28.

Department of Oncology, Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA.

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http://dx.doi.org/10.1093/carcin/bgq017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847093PMC
April 2010

Childhood exposure to secondhand smoke and functional mannose binding lectin polymorphisms are associated with increased lung cancer risk.

Cancer Epidemiol Biomarkers Prev 2009 Dec;18(12):3375-83

Cancer Prevention Fellowship Program, Office of Preventive Oncology, Division of Cancer Prevention, Laboratory of Human Carcinogenesis, CCR, NCI, NIH, Bethesda, MD 20892-4258, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951599PMC
December 2009

Viral and non-viral risk factors for non-Hodgkin's lymphoma in Egypt: heterogeneity by histological and immunological subtypes.

Cancer Causes Control 2009 Aug 5;20(6):981-7. Epub 2009 Mar 5.

Lombardi Cancer Center, Georgetown University, 3800 Reservoir Rd, PO Box 571465, Washington, DC 20057-1465, USA.

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http://dx.doi.org/10.1007/s10552-009-9316-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584638PMC
August 2009

Chromosome 9 arm-specific telomere length and breast cancer risk.

Carcinogenesis 2009 Aug 17;30(8):1380-6. Epub 2009 Jun 17.

Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA.

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http://dx.doi.org/10.1093/carcin/bgp151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718080PMC
August 2009

Detection of hepatocellular carcinoma using glycomic analysis.

Clin Cancer Res 2009 Mar 17;15(5):1808-13. Epub 2009 Feb 17.

Department of Oncology, Georgetown University, Washington, District of Columbia 20057-1469, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-5261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850198PMC
March 2009

Nondaily, light daily, and moderate-to-heavy cigarette smokers in a rural area of Egypt: a population-based survey.

Nicotine Tob Res 2009 Feb 26;11(2):134-8. Epub 2009 Feb 26.

Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

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http://dx.doi.org/10.1093/ntr/ntp016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658907PMC
February 2009

Genotoxic effects of waterpipe smoking on the buccal mucosa cells.

Mutat Res 2008 Aug-Sep;655(1-2):36-40

Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

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http://dx.doi.org/10.1016/j.mrgentox.2008.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568951PMC
December 2008

Occupation, gender, race, and lung cancer.

J Occup Environ Med 2008 Oct;50(10):1167-75

Departments of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1097/JOM.0b013e31817d3639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585362PMC
October 2008

Ant colony optimization for biomarker identification from MALDI-TOF mass spectra.

Conf Proc IEEE Eng Med Biol Soc 2006 ;1:4560-3

Lombardi Comprehensive Cancer Center, Georgetown Univ., Washington, DC, USA.

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http://dx.doi.org/10.1109/IEMBS.2006.260707DOI Listing
April 2008

Tumor immunobiological differences in prostate cancer between African-American and European-American men.

Cancer Res 2008 Feb;68(3):927-36

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-4258, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-2608DOI Listing
February 2008

Behavioral risk factors among Black and White women newly diagnosed with breast cancer.

Psychooncology 2007 Mar;16(3):224-31

Cancer Control Program, Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC 20007-2401, USA.

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http://dx.doi.org/10.1002/pon.1076DOI Listing
March 2007

Evaluation of Papanicolaou stain for studying micronuclei in buccal cells under field conditions.

Acta Cytol 2006 Jul-Aug;50(4):398-402

Cytopathology and Early Cancer Detection Unit, Ain Shams University Hospitals, Egypt.

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http://dx.doi.org/10.1159/000325980DOI Listing
September 2006

On using a cancer center cancer registry to identify newly affected women eligible for hereditary breast cancer syndrome testing: practical considerations.

J Genet Couns 2006 Apr;15(2):129-36

Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia 20007-2401, USA.

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http://dx.doi.org/10.1007/s10897-005-9006-3DOI Listing
April 2006

Analysis of mass spectral serum profiles for biomarker selection.

Bioinformatics 2005 Nov 13;21(21):4039-45. Epub 2005 Sep 13.

Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.

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http://dx.doi.org/10.1093/bioinformatics/bti670DOI Listing
November 2005

Genetic and environmental influences on malformations of the cardiac outflow tract.

Expert Rev Cardiovasc Ther 2005 Nov;3(6):1125-30

Cardiology, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1586/14779072.3.6.1125DOI Listing
November 2005

Case-control study of non-Hodgkin's lymphoma and hepatitis C virus infection in Egypt.

Int J Epidemiol 2004 Oct 20;33(5):1034-9. Epub 2004 May 20.

Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, USA.

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http://dx.doi.org/10.1093/ije/dyh183DOI Listing
October 2004

Fetal ADH2*3, maternal alcohol consumption, and fetal growth.

Int J Toxicol 2004 Jan-Feb;23(1):47-54

Toxicology Program, University of Maryland, Baltimore, Maryland, USA.

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http://journals.sagepub.com/doi/10.1080/10915810490265450
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http://dx.doi.org/10.1080/10915810490265450DOI Listing
September 2004

Variability in human metabolism of arsenic.

Environ Res 2003 Jun;92(2):85-91

Program in Human Health and the Environment, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1016/s0013-9351(02)00081-6DOI Listing
June 2003

Population-based study of l-transposition of the great arteries: possible associations with environmental factors.

Birth Defects Res A Clin Mol Teratol 2003 Mar;67(3):162-7

Department of Cardiology, Children's National Medical Center, George Washington University School of Medicine, Washington, DC 20010, USA.

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http://dx.doi.org/10.1002/bdra.10015DOI Listing
March 2003

Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls.

Carcinogenesis 2003 Feb;24(2):269-74

Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1093/carcin/24.2.269DOI Listing
February 2003

Infants with single ventricle: a population-based epidemiological study.

Teratology 2002 Mar;65(3):106-15

Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1002/tera.10017DOI Listing
March 2002