Christophe Lefebvre

Christophe Lefebvre

UNVERIFIED PROFILE

Are you Christophe Lefebvre?   Register this Author

Register author
Christophe Lefebvre

Christophe Lefebvre

Publications by authors named "Christophe Lefebvre"

Are you Christophe Lefebvre?   Register this Author

34Publications

485Reads

20Profile Views

Isolation of microglia-derived extracellular vesicles: towards miRNA signatures and neuroprotection.

J Nanobiotechnology 2019 Dec 4;17(1):119. Epub 2019 Dec 4.

Laboratoire de Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), INSERM U1192, Université de Lille, 59000, Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12951-019-0551-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894150PMC
December 2019

Autophagy mediates phosphatidylserine exposure and phagosome degradation during apoptosis through specific functions of GABARAP/LGG-1 and LC3/LGG-2.

Autophagy 2019 02 10;15(2):228-241. Epub 2018 Sep 10.

a Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS , Univ. Paris-Sud, Université Paris-Saclay , Gif-sur-Yvette cedex , France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15548627.2018.1512452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333449PMC
February 2019

Three-Dimensional Surface Rendering of ESCRT Proteins Microscopy Data Using UCSF Chimera Software.

Methods Mol Biol 2019 ;1998:149-161

Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, Université Paris-Saclay, Gif-sur-Yvette, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9492-2_11DOI Listing
January 2019

Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons.

Int J Mol Sci 2018 Dec 19;19(12). Epub 2018 Dec 19.

U1192-Laboratoire Protéomique, Réponse Inflammatoire et Spectrométrie de Masse (PRISM), Univ. Lille, INSERM, F-59000 Lille, France.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1422-0067/19/12/4124
Publisher Site
http://dx.doi.org/10.3390/ijms19124124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321190PMC
December 2018

ESCRT and autophagies: Endosomal functions and beyond.

Semin Cell Dev Biol 2018 02 12;74:21-28. Epub 2017 Aug 12.

Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, 91198, Gif-sur-Yvette Cedex, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcdb.2017.08.014DOI Listing
February 2018

The ESCRT-II proteins are involved in shaping the sarcoplasmic reticulum in C. elegans.

J Cell Sci 2016 Apr 18;129(7):1490-9. Epub 2016 Feb 18.

Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, Université Paris-Saclay, Gif-sur-Yvette cedex 91198, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.178467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518307PMC
April 2016

Modulation properties of factors released by bone marrow stromal cells on activated microglia: an in vitro study.

Sci Rep 2014 Dec 19;4:7514. Epub 2014 Dec 19.

Laboratoire PRISM: Protéomique, Réponse Inflammatoire, Spectrométrie de Masse, -U1192 INSERM, Bât SN3, 1er étage, Université de Lille 1, F-59655 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep07514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378994PMC
December 2014

Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to vertebrate ionized calcium-binding adapter molecule 1 (Iba1/alias aif-1).

Dev Neurobiol 2014 Oct 22;74(10):987-1001. Epub 2014 Apr 22.

Université Lille 1, Laboratoire de Spectrométrie de Masse Biologique Fondamentale et Appliquée, EA4550, Villeneuve d'Ascq, 59655, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dneu.22179DOI Listing
October 2014

Human GABARAP can restore autophagosome biogenesis in a C. elegans lgg-1 mutant.

Autophagy 2014 Oct 23;10(10):1868-72. Epub 2014 Jul 23.

Centre de Génétique Moléculaire; CNRS UPR3404;Université Paris Sud; Gif-sur-Yvette, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/auto.29745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198372PMC
October 2014

Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during Caenorhabditis elegans development.

Methods Enzymol 2014 ;534:93-118

Centre de Génétique Moléculaire, CNRS UPR3404, Université Paris-Sud, 91198 Gif-sur-Yvette Cedex, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-397926-1.00006-8DOI Listing
July 2014

Alterations of protein composition along the rostro-caudal axis after spinal cord injury: proteomic, in vitro and in vivo analyses.

Front Cell Neurosci 2014 17;8:105. Epub 2014 Apr 17.

Laboratoire de Spectrométrie de Masse Biologique Fondamentale et Appliquée, EA 4550, FRE CNRS 3637, Université Lille 1 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fncel.2014.00105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028999PMC
May 2014

Calreticulin contributes to C1q-dependent recruitment of microglia in the leech Hirudo medicinalis following a CNS injury.

Med Sci Monit 2014 Apr 19;20:644-53. Epub 2014 Apr 19.

Laboratoire de Spectrométrie de Masse Biologique Fondamentale et Appliquée - EA4550, Université Lille Nord de France, University of Lille 1, Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12659/MSM.890091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999160PMC
April 2014

The leech nervous system: a valuable model to study the microglia involvement in regenerative processes.

Clin Dev Immunol 2013 26;2013:274019. Epub 2013 Jun 26.

Fundamental and Applied Biology and Mass Spectrometry, FABMS-PRISM, Lille 1 University, IFR 147, SN3, 59655 Villeneuve d'Ascq Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2013/274019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710617PMC
February 2014

The C. elegans LC3 acts downstream of GABARAP to degrade autophagosomes by interacting with the HOPS subunit VPS39.

Dev Cell 2014 Jan 26;28(1):43-55. Epub 2013 Dec 26.

Centre de Génétique Moléculaire, CNRS UPR3404 associée à l'Université Paris Sud, Avenue de la terrasse, 91198 Gif-sur-Yvette Cedex, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2013.11.022DOI Listing
January 2014

Need an ESCRT for autophagosomal maturation?

Commun Integr Biol 2012 Nov;5(6):566-71

Centre de Génétique Moléculaire; Université Paris-Sud; CNRS UPR3404; Gif-sur-Yvette Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cib.21522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3541323PMC
November 2012

Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis.

J Neuroinflammation 2012 Feb 22;9:37. Epub 2012 Feb 22.

Laboratoire de Spectrométrie de Masse Biologique Fondamentale et Appliquée - EA4550, Microglial activation group, Université Lille Nord de France, Université Lille 1, IFR 147, bâtiment SN3, 59655 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1742-2094-9-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298539PMC
February 2012

A case of myocardial infarction not to be stented too quickly...

Acta Cardiol 2011 Jun;66(3):379-82

Jessaziekenhuis Hasselt, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/ac.66.3.2114141DOI Listing
June 2011

A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis.

Glia 2010 Nov;58(14):1649-62

Université Lille Nord de France, Université Lille 1, Laboratoire de Neuroimmunologie des Annélides, Centre National de la Recherche Scientifique, FRE 3249, IFR 147, F59655 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/glia.21036
Publisher Site
http://dx.doi.org/10.1002/glia.21036DOI Listing
November 2010

Separating the spindle, checkpoint, and timer functions of BubR1.

J Cell Biol 2009 Nov;187(5):597-605

Institut Jacques Monod, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7592, Université Paris Diderot, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200905026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806589PMC
November 2009

Is complement good, bad, or both? New functions of the complement factors associated with inflammation mechanisms in the central nervous system.

Eur Cytokine Netw 2009 Sep;20(3):95-100

Université de Lille 1, Sciences et Technologies, Laboratoire de Neuro-Immunologie des Annélides, CNRS FRE 2933, IFR 147, Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/ecn.2009.0157DOI Listing
September 2009

The ESCRT-III protein CeVPS-32 is enriched in domains distinct from CeVPS-27 and CeVPS-23 at the endosomal membrane of epithelial cells.

Biol Cell 2009 Jul 31;101(10):599-615. Epub 2009 Jul 31.

Centre de Génétique Moléculaire, CNRS UPR 2167, bâtiment 26, Gif-sur-Yvette Cedex, 91198, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1042/BC20090025
Publisher Site
http://dx.doi.org/10.1042/BC20090025DOI Listing
July 2009

Increased IP3/Ca2+ signaling compensates depletion of LET-413/DLG-1 in C. elegans epithelial junction assembly.

Dev Biol 2009 Mar 7;327(1):34-47. Epub 2008 Dec 7.

Institute for Genetics, Heinrich-Heine-University Duesseldorf, D-40225 Duesseldorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ydbio.2008.11.025DOI Listing
March 2009

Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord.

Mol Immunol 2009 Feb 25;46(4):523-31. Epub 2008 Oct 25.

Université de Lille 1 (USTL), Laboratoire de Neuroimmunologie des Annélides, Centre National de la Recherche Scientifique, FRE 2933, IFR 147, F59655 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2008.07.026DOI Listing
February 2009

Cathepsin L and cystatin B gene expression discriminates immune coelomic cells in the leech Theromyzon tessulatum.

Dev Comp Immunol 2008 26;32(7):795-807. Epub 2007 Dec 26.

Université de Lille 1, Laboratoire de Neuroimmunologie des Annélides, FRE 2933 Centre National de Recherche Scientifique (CNRS), IFR147, Bâtiment SN3, Université de Lille1, 59655 Villeneuve d'Ascq cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dci.2007.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782477PMC
August 2008

CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans.

Traffic 2005 Aug;6(8):695-705

Centre de Génétique Moléculaire, CNRS UPR 2167, Avenue de la terrasse, bâtiment 26, 91198 Gif-sur-Yvette Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0854.2005.00309.xDOI Listing
August 2005

Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex.

Curr Biol 2005 May;15(9):856-61

Centre National de la Recherche Scientifique, Centre de Génétique Moléculaire, Avenue de la Terrasse, 91198 Gif sur Yvette, France.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S096098220500396
Publisher Site
http://dx.doi.org/10.1016/j.cub.2005.03.052DOI Listing
May 2005

Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum.

J Biol Chem 2004 Jul 21;279(30):30973-82. Epub 2004 Apr 21.

Centre National de la Recherche Scientifique, Laboratoire de Neuroimmunologie UMR 8017, SN3, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M312156200
Publisher Site
http://dx.doi.org/10.1074/jbc.M312156200DOI Listing
July 2004

Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity.

Biochem J 2004 Jun;380(Pt 3):617-25

Laboratoire de Neuroimmunologie des Annélides, UMR CNRS 8017, SN3, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq, France.

View Article

Download full-text PDF

Source
http://biochemj.org/lookup/doi/10.1042/bj20040478
Publisher Site
http://dx.doi.org/10.1042/BJ20040478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224237PMC
June 2004

In vivo dynamics of the rough deal checkpoint protein during Drosophila mitosis.

Curr Biol 2004 Jan;14(1):56-61

Centre de National de Récherche Scientifique, Centre de Génétique Moléculaire, Avenue de la Terasse, 91198, Gif-sur-Yvette, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2003.12.025DOI Listing
January 2004

DOC1R: a MAP kinase substrate that control microtubule organization of metaphase II mouse oocytes.

Development 2003 Nov 27;130(21):5169-77. Epub 2003 Aug 27.

UMR 7622, CNRS, Université Paris VI, 9 quai Saint Bernard, Bat. C, 75252 Paris, cedex 05, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.00731DOI Listing
November 2003

Annelid neuroimmune system.

Curr Pharm Des 2003 ;9(2):149-58

Laboratoire de Neuroimmunologie des Annélides, UMR CNRS 8017, SN3, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq Cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612033392251DOI Listing
June 2003

Gene expression changes in Schistosoma mansoni sporocysts induced by Biomphalaria glabrata embryonic cells.

Parasitol Res 2003 Jan 14;89(2):113-9. Epub 2002 Sep 14.

Unité INSERM 547, Institut Pasteur de Lille, 1 rue du Pr. Calmette, 59019 Lille Cedex, France.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00436-002-0643-2
Publisher Site
http://dx.doi.org/10.1007/s00436-002-0643-2DOI Listing
January 2003

Meiotic spindle stability depends on MAPK-interacting and spindle-stabilizing protein (MISS), a new MAPK substrate.

J Cell Biol 2002 May 13;157(4):603-13. Epub 2002 May 13.

Biologie Cellulaire et Moléculaire du Developpement, Centre National de la Recherche Scientifique, Université Pierre et Marie Curie, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200202052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173866PMC
May 2002