Publications by authors named "Christoph S Clemen"

58Publications

Growing Old Too Early: Skeletal Muscle Single Fiber Biomechanics in Ageing R349P Desmin Knock-in Mice Using the Technology.

Int J Mol Sci 2020 Jul 31;21(15). Epub 2020 Jul 31.

Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Bavaria, Germany.

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http://dx.doi.org/10.3390/ijms21155501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432536PMC
July 2020

Functional Characterisation of the Autophagy ATG12~5/16 Complex in .

Cells 2020 May 9;9(5). Epub 2020 May 9.

Centre for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.3390/cells9051179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290328PMC
May 2020

Multisystem proteinopathy due to a homozygous p.Arg159His mutation: A tale of the unexpected.

Neurology 2020 02 17;94(8):e785-e796. Epub 2019 Dec 17.

From the Neurogenetics Group (W.D.R., P.D.J., J.B.), Laboratory of Neuromuscular Pathology (W.D.R., P.D.J., J.B.), Institute Born-Bunge, Neuromics Support Facility (A.A.), VIB-UAntwerp Center for Molecular Neurology, and Receptor Biology Lab (S.M.), Department of Biomedical Sciences, University of Antwerp; Neuromuscular Reference Centre (W.D.R., P.D.J., J.B.), Department of Neurology, Antwerp University Hospital, Belgium; Institute of Neuropathology (C.S.C., R.S.), University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen; Centre for Biochemistry (C.S.C., L.E.), Institute of Biochemistry I, and Center for Physiology and Pathophysiology (C.S.C.), Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Germany; Griffith Institute for Drug Discovery (A.H), Griffith University, Nathan, Brisbane, Queensland; Department of Veterinary Biosciences (A.H.), Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia; John Walton Muscular Dystrophy Research Centre (K.J., A.T., V.S.), Institute of Genetic Medicine, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle-Upon-Tyne, UK; and Laboratory for Neuropathology (J.L.D.B.), Division of Neurology, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.1212/WNL.0000000000008763DOI Listing
February 2020

CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.

Eur J Cell Biol 2019 Dec 11;98(5-8):151046. Epub 2019 Oct 11.

Centre for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931, Cologne, Germany; Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054, Erlangen, Germany; Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, 50931, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2019.151046DOI Listing
December 2019

A convenient tool for bivariate data analysis and bar graph plotting with R.

Biochem Mol Biol Educ 2019 03 10;47(2):207-210. Epub 2019 Jan 10.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/bmb.21205DOI Listing
March 2019

Expression of N471D strumpellin leads to defects in the endolysosomal system.

Dis Model Mech 2018 09 13;11(9). Epub 2018 Sep 13.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931 Cologne, Germany

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http://dx.doi.org/10.1242/dmm.033449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177004PMC
September 2018

[Inclusion Body Myopathy, Paget's Disease, and Fronto-temporal Dementia: a VCP-related Multi-systemic Proteinopathy].

Fortschr Neurol Psychiatr 2018 07 20;86(7):434-438. Epub 2018 Jul 20.

Institut für Neuropathologie, Universitätsklinikum Erlangen, Erlangen.

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http://dx.doi.org/10.1055/s-0044-101033DOI Listing
July 2018

Aging-related mitochondrial dysfunction facilitates the occurrence of serious arrhythmia after myocardial infarction.

Biochem Biophys Res Commun 2017 11 1;493(1):604-610. Epub 2017 Sep 1.

Department of Internal Medicine II, University Hospital Bonn, Rheinische Friedrich-Wilhelms University, Bonn, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2017.08.145DOI Listing
November 2017

Preaged remodeling of myofibrillar cytoarchitecture in skeletal muscle expressing R349P mutant desmin.

Neurobiol Aging 2017 10 13;58:77-87. Epub 2017 Jun 13.

Institute of Medical Biotechnology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany; SAOT, Erlangen Graduate School in Advanced Optical Technologies, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany; Muscle Research Center Erlangen (MURCE), Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.06.001DOI Listing
October 2017

Genetic analysis of VCP and WASH complex genes in a German cohort of sporadic ALS-FTD patients.

Neurobiol Aging 2017 08 3;56:213.e1-213.e5. Epub 2017 May 3.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, Cologne, Germany; Department of Neurology, Heimer Institute for Muscle Research, University Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.04.023DOI Listing
August 2017

The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype.

Am J Hum Genet 2016 09 4;99(3):647-665. Epub 2016 Aug 4.

Institute of Human Genetics, University of Cologne, 50931 Cologne Germany; Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011078PMC
September 2016

Neuromuscular endplate pathology in recessive desminopathies: Lessons from man and mice.

Neurology 2016 Aug 20;87(8):799-805. Epub 2016 Jul 20.

From the Department of Neurology (H.D., F.D., Y.P., P.S.-O.), Faculty of Medicine, Istanbul University; Department of Molecular Biology and Genetics (Ö.A., A.T.), Boğaziçi University, Istanbul, Turkey; Children's National Medical Center (S.Ç.), Research Center for Genetic Medicine, Washington, DC; Department of Pediatrics, Institute for Human Genetics, and Center for Molecular Medicine, University Hospital Cologne; Institute of Clinical Molecular Biology (A.F., G.H.-S.), Christian-Albrechts-University of Kiel; Institute of Biochemistry (N.E., S.H.), Institute of Neuropathology (F.C., R.S.), and Department of Ophthalmology (U.S.-S.), Friedrich-Alexander-University of Erlangen-Nuremberg; and Center for Biochemistry, Institute of Biochemistry I, Medical Faculty (C.S.C.), University of Cologne, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000003004DOI Listing
August 2016

Coronin 1C-free primary mouse fibroblasts exhibit robust rearrangements in the orientation of actin filaments, microtubules and intermediate filaments.

Eur J Cell Biol 2016 Aug 4;95(8):239-51. Epub 2016 May 4.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2016.04.004DOI Listing
August 2016

Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerisation of p97 hexamers.

Eur J Cell Biol 2016 Jun-Jul;95(6-7):195-207. Epub 2016 Apr 7.

Centre for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2016.03.004DOI Listing
February 2017

TRANSPARENT TESTA GLABRA1 and GLABRA1 Compete for Binding to GLABRA3 in Arabidopsis.

Plant Physiol 2015 Jun 29;168(2):584-97. Epub 2015 Apr 29.

Biocenter, Cologne University, Botanical Institute, 50674 Cologne, Germany (M.P., I.S., K.K., J.F.U., M.H.);Preclinical Target Development and Genomics and Proteomics Core Facilities, German Cancer Research Center, 69120 Heidelberg, Germany (M.K.);Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, Cologne University, 50931 Cologne, Germany (C.S.C.); andHeinrich-Heine Universität Düsseldorf, 40225 Dusseldorf, Germany (R.S., S.W.-P.)

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http://dx.doi.org/10.1104/pp.15.00328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453790PMC
June 2015

Identification of the protein kinases Pyk3 and Phg2 as regulators of the STATc-mediated response to hyperosmolarity.

PLoS One 2014 25;9(2):e90025. Epub 2014 Feb 25.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, Cologne, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090025PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934975PMC
October 2014

CRN2 enhances the invasiveness of glioblastoma cells.

Neuro Oncol 2013 May 14;15(5):548-61. Epub 2013 Feb 14.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, Hamburg, Germany.

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http://dx.doi.org/10.1093/neuonc/nos388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635520PMC
May 2013

Desminopathies: pathology and mechanisms.

Acta Neuropathol 2013 Jan 11;125(1):47-75. Epub 2012 Nov 11.

Institute of Biochemistry I, Medical Faculty, University of Cologne, Joseph-Stelzmann-Street 52, 50931 Cologne, Germany.

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http://link.springer.com/10.1007/s00401-012-1057-6
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http://dx.doi.org/10.1007/s00401-012-1057-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535371PMC
January 2013

Proteasomal activity in skeletal muscle: a matter of assay design, muscle type, and age.

Anal Biochem 2010 Apr 23;399(2):225-9. Epub 2009 Dec 23.

Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.1016/j.ab.2009.12.026DOI Listing
April 2010

The role of mammalian coronins in development and disease.

Subcell Biochem 2008 ;48:124-35

Lineberger Comprehensive Cancer Center and Department of Cell and Developmental Biology, UNC-Chapel Hill, Chapel Hill, NC 27599, USA.

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http://link.springer.com/10.1007/978-0-387-09595-0_12
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http://dx.doi.org/10.1007/978-0-387-09595-0_12DOI Listing
November 2008

Evolutionary and functional diversity of coronin proteins.

Subcell Biochem 2008 ;48:98-109

Center for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, Cologne, Germany.

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http://dx.doi.org/10.1007/978-0-387-09595-0_9DOI Listing
November 2008

The coronin family of proteins.

Subcell Biochem 2008 ;48:1-5

Center for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, Cologne, Germany.

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http://dx.doi.org/10.1007/978-0-387-09595-0_1DOI Listing
November 2008

Coronin 3 involvement in F-actin-dependent processes at the cell cortex.

Exp Cell Res 2007 Mar 30;313(5):878-95. Epub 2006 Dec 30.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Cologne, Germany.

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http://dx.doi.org/10.1016/j.yexcr.2006.12.015DOI Listing
March 2007

Alpha-actinin 4 and BAT1 interaction with the cytochrome c promoter upon skeletal muscle differentiation.

Curr Genet 2006 Feb 6;49(2):125-35. Epub 2005 Dec 6.

Institute of Vegetative Physiology, Medical Faculty, University of Köln, Germany.

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http://link.springer.com/10.1007/s00294-005-0043-0
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http://dx.doi.org/10.1007/s00294-005-0043-0DOI Listing
February 2006

Coronin proteins as multifunctional regulators of the cytoskeleton and membrane trafficking.

Bioessays 2005 Jun;27(6):625-32

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, Germany.

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http://dx.doi.org/10.1002/bies.20235DOI Listing
June 2005

Nuclear localization of Annexin A7 during murine brain development.

BMC Neurosci 2005 Apr 10;6:25. Epub 2005 Apr 10.

Center for Biochemistry, Institute of Biochemistry I, Medical Faculty and Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str, 52, 50931 Köln, Germany.

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http://dx.doi.org/10.1186/1471-2202-6-25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087847PMC
April 2005

Coronin 3 and its role in murine brain morphogenesis.

Eur J Neurosci 2005 Mar;21(5):1155-68

Center for Biochemistry and Center of Molecular Medicine Cologne, Medical Faculty, University of Cologne, Joseph-Stelzmann-Strasse 52, D-50931 Koeln, Germany.

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http://doi.wiley.com/10.1111/j.1460-9568.2005.03917.x
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http://dx.doi.org/10.1111/j.1460-9568.2005.03917.xDOI Listing
March 2005

The lack of annexin A7 affects functions of primary astrocytes.

Exp Cell Res 2003 Dec;291(2):406-14

Center for Biochemistry, Medical Faculty, University of Cologne, Joseph-Stelzmann-Str. 52, 50931 Cologne, Federal Republic of Germany.

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http://dx.doi.org/10.1016/j.yexcr.2003.07.012DOI Listing
December 2003