Christoph Plass

Christoph Plass

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Christoph Plass

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Editorial: The International Journal of Cancer - quo vadis?

Authors:
Christoph Plass

Int J Cancer 2019 Dec 30;145(12):3193. Epub 2019 Aug 30.

Division of Cancer Epigenomics, German Cancer Research Center, Heidelberg, Germany, Editor-in-Chief, International Journal of Cancer.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32604
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http://dx.doi.org/10.1002/ijc.32604DOI Listing
December 2019

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns.

Nucleic Acids Res 2019 Dec;47(21):11355-11367

Institute of Biochemistry and Technical Biochemistry, Department of Biochemistry, Stuttgart University, Allmandring 31, 70569 Stuttgart, Germany.

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http://dx.doi.org/10.1093/nar/gkz911DOI Listing
December 2019

Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze.

Allergy 2019 Oct 21;74(10):2002-2006. Epub 2019 May 21.

Molecular Epidemiology Unit, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, associated partner of the German Center for Lung Research (DZL), Berlin, Germany.

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http://dx.doi.org/10.1111/all.13837DOI Listing
October 2019

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia.

Leukemia 2019 07 24;33(7):1805-1810. Epub 2019 Jan 24.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0343-2DOI Listing
July 2019

Generation of Whole Genome Bisulfite Sequencing Libraries from Very Low DNA Input.

Methods Mol Biol 2019 ;1956:229-248

Cancer Epigenomics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-9151-8_10DOI Listing
July 2019

Interaction between genetic ancestry and common breast cancer susceptibility variants in Colombian women.

Int J Cancer 2019 05 5;144(9):2181-2191. Epub 2019 Jan 5.

Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://doi.wiley.com/10.1002/ijc.32023
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http://dx.doi.org/10.1002/ijc.32023DOI Listing
May 2019

Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues.

Electrophoresis 2019 05 14;40(9):1293-1297. Epub 2019 Feb 14.

Division of Radiopharmaceutical Chemistry, Heidelberg, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/elps.2018005
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http://dx.doi.org/10.1002/elps.201800523DOI Listing
May 2019

Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation.

Leukemia 2019 04 23;33(4):945-956. Epub 2018 Nov 23.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Internal Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41375-018-0293-8DOI Listing
April 2019

Transcriptome and protein interaction profiling in cancer cells with mutations in histone H3.3.

Sci Data 2018 12 11;5:180283. Epub 2018 Dec 11.

Graduate School of Cancer Science and Policy, Cancer Biomedical Science, National Cancer Center, Gyeonggi-do, Republic of Korea.

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http://dx.doi.org/10.1038/sdata.2018.283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289111PMC
December 2018

From Basic Knowledge to Effective Therapies.

Cancer Cell 2018 12;34(6):871-873

Division of Cancer Epigenomics, German Cancer Research Center, Heidelberg, Germany; The German Cancer Research Consortium. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.11.013DOI Listing
December 2018

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories.

Cancer Cell 2018 12;34(6):996-1011.e8

Finsen Laboratory, Rigshospitalet, DK-2200, Copenhagen, Denmark; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, DK-2200, Copenhagen, Denmark; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, 69120 Heidelberg, Germany; Charité Universitätsmedizin Berlin, Charitéplatz 1, D-10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.10.016DOI Listing
December 2018

Maftools: efficient and comprehensive analysis of somatic variants in cancer.

Genome Res 2018 11 19;28(11):1747-1756. Epub 2018 Oct 19.

Cancer Science Institute of Singapore, National University of Singapore, 117599, Singapore.

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http://genome.cshlp.org/lookup/doi/10.1101/gr.239244.118
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http://dx.doi.org/10.1101/gr.239244.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211645PMC
November 2018

Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact.

Semin Cancer Biol 2018 08 7;51:1-11. Epub 2018 Feb 7.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2018.02.001DOI Listing
August 2018

Introduction: Epigenetics in cancer.

Semin Cancer Biol 2018 08 7;51:iv-v. Epub 2018 Jul 7.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X183008
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http://dx.doi.org/10.1016/j.semcancer.2018.07.002DOI Listing
August 2018

Tagmentation-Based Library Preparation for Low DNA Input Whole Genome Bisulfite Sequencing.

Methods Mol Biol 2018 ;1708:105-122

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/978-1-4939-7481-8_6
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http://dx.doi.org/10.1007/978-1-4939-7481-8_6DOI Listing
July 2018

Enrichment analysis with EpiAnnotator.

Bioinformatics 2018 05;34(10):1781-1783

Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bty007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946894PMC
May 2018

Early-onset childhood atopic dermatitis is related to NLRP2 repression.

J Allergy Clin Immunol 2018 04 9;141(4):1482-1485.e16. Epub 2017 Dec 9.

Department of Environmental Immunology, Helmholtz Centre for Environmental Research Leipzig, Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.018DOI Listing
April 2018

Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.

J Allergy Clin Immunol 2018 02 6;141(2):741-753. Epub 2017 Apr 6.

Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.03.017DOI Listing
February 2018

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Nat Commun 2017 12 19;8(1):2127. Epub 2017 Dec 19.

Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, 1450 3rd Street, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1038/s41467-017-02178-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736624PMC
December 2017

Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.

Circulation 2017 Oct 24;136(16):1528-1544. Epub 2017 Aug 24.

From Department of Internal Medicine III, Institute for Cardiomyopathies, University of Heidelberg, Germany (B.M., J.H., F.S.-H., E.K., K.F., A.L., R.N., C.S., S.M., D.M.-B., A.A., H.H., D.B.H., M.M.-H., T.W., H.A.K.); Siemens Healthcare GmbH, Strategy and Innovation, Erlangen, Germany (C.D., M.W., A.E.P.); Department of Bioinformatics, University of Saarland, Saarbrücken, Germany (A.K.); German Centre for Cardiovascular Research, Berlin, Germany (B.M., J.H., F.S.-H., E.K., K.F., A.L., D.S., M.M.-H., T.W., J.B., H.A.K.); Institute for Molecular Cardiology and Epigenetics, University of Heidelberg, Germany (D.S., J.B.); Funktionelle Genomanalyse, Deutsches Krebsforschungszentrum, Heidelberg, Germany (A.B.); Department of Cardiac Surgery, University of Heidelberg, Germany (A.R.); Siemens AG, Corporate Technology, Vienna, Austria (D.P.); Section for Clinical Biometrics, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Austria (D.P.); and Division of Epigenomics and Cancer Risk Factors, Deutsches Krebsforschungszentrum, Heidelberg, Germany (D.W., C.P.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.117.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027355DOI Listing
October 2017

BET-bromodomain inhibitors modulate epigenetic patterns at the diacylglycerol kinase alpha enhancer associated with radiation-induced fibrosis.

Radiother Oncol 2017 10 12;125(1):168-174. Epub 2017 Sep 12.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01678140173255
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http://dx.doi.org/10.1016/j.radonc.2017.08.028DOI Listing
October 2017

Epigenetic dysregulation of the erythropoietic transcription factor KLF1 and the β-like globin locus in juvenile myelomonocytic leukemia.

Epigenetics 2017 08 27;12(8):715-723. Epub 2017 Jul 27.

a Department of Pediatrics and Adolescent Medicine , Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg , Freiburg , Germany.

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http://dx.doi.org/10.1080/15592294.2017.1356959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687323PMC
August 2017

Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response.

Stem Cell Reports 2017 05 6;8(5):1379-1391. Epub 2017 Apr 6.

Skin Cancer Unit (G300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, 68167 Mannheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425615PMC
May 2017

150 years of Johann Gregor Mendel's "Versuche über Pflanzen-Hybriden".

Mol Genet Genomics 2017 Feb 11;292(1):1-3. Epub 2016 Oct 11.

Institut für Biologie und Umweltwissenschaften, Fakultät Mathematik und Naturwissenschaften, Carl-von-Ossietzky-Universität Oldenburg, Ammerländer Heerstraße 114-118, 26129, Oldenburg, Germany.

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http://dx.doi.org/10.1007/s00438-016-1254-4DOI Listing
February 2017

CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.

Clin Epigenetics 2016 5;8:50. Epub 2016 May 5.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center, Mathildenstrasse 1, 79106 Freiburg, Germany.

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http://dx.doi.org/10.1186/s13148-016-0216-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858931PMC
December 2016

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis.

Lancet Oncol 2016 Oct 27;17(10):1386-1395. Epub 2016 Aug 27.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet, Barcelona, Catalonia, Spain; School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30297-2DOI Listing
October 2016

Assessment of Promoter Methylation Identifies PTCH as a Putative Tumor-suppressor Gene in Human CLL.

Anticancer Res 2016 09;36(9):4515-9

Department of Neuropathology, University Hospital, Bonn, Germany.

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http://dx.doi.org/10.21873/anticanres.10998DOI Listing
September 2016

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL.

Blood 2016 08 14;128(6):816-26. Epub 2016 Jun 14.

Haematology Oncology Group, Cancer Sciences Unit, and Cancer Sciences Unit, Cancer Research UK and National Institute for Health Research (NIHR) Experimental Cancer Medicine Centres, University of Southampton, Southampton, United Kingdom; Haematology Department, University Hospital Southampton NHS Trust, Southampton, United Kingdom.

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http://dx.doi.org/10.1182/blood-2016-03-707786DOI Listing
August 2016

Increased vitamin D levels at birth and in early infancy increase offspring allergy risk-evidence for involvement of epigenetic mechanisms.

J Allergy Clin Immunol 2016 Feb 15;137(2):610-3. Epub 2015 Aug 15.

Department of Environmental Immunology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany; Core Facility Studies, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.040DOI Listing
February 2016

Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia.

Int J Cancer 2015 Sep 13;137(6):1352-61. Epub 2015 Mar 13.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29491DOI Listing
September 2015

Mutational dynamics between primary and relapse neuroblastomas.

Nat Genet 2015 Aug 29;47(8):872-7. Epub 2015 Jun 29.

1] Pediatric Oncology and Hematology, University Children's Hospital Essen, University of Duisburg-Essen, Essen, Germany. [2] Pediatric Oncology and Hematology, Charité University Medicine, Berlin, Germany. [3] German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://search.proquest.com/openview/bef3fe020af3cd6708016aba
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http://dx.doi.org/10.1038/ng.3349DOI Listing
August 2015

PRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells.

Sci Rep 2015 Jul 22;5:12319. Epub 2015 Jul 22.

Institute of Medical Radiology and Cell Research (MSZ) in the Center for Experimental Molecular Medicine (ZEMM), University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1038/srep12319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510577PMC
July 2015

DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood.

Int J Cancer 2015 Apr 24;136(8):1845-55. Epub 2014 Sep 24.

Molecular Biology of Breast Cancer, Department of Gynecology and Obstetrics, University of Heidelberg, Heidelberg, Germany; Molecular Epidemiology (C080), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29205DOI Listing
April 2015

Transient DNMT1 suppression reveals hidden heritable marks in the genome.

Nucleic Acids Res 2015 Feb 10;43(3):1485-97. Epub 2015 Jan 10.

Departments of Pediatrics, Human Genetics and Pharmacology & Therapeutics, McGill University and the Research Institute of the McGill University Health Centre at the Montreal Children's Hospital, Montreal, QC H3Z 2Z3, Canada

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http://dx.doi.org/10.1093/nar/gku1386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330356PMC
February 2015

Reduced promoter methylation and increased expression of CSPG4 negatively influences survival of HNSCC patients.

Int J Cancer 2014 Dec 26;135(11):2727-34. Epub 2014 Apr 26.

Department of Otorhinolaryngology, Head and Neck Surgery, University of Heidelberg, Heidelberg, Germany; Division of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.28906DOI Listing
December 2014

Pan-cancer patterns of DNA methylation.

Genome Med 2014 30;6(8):66. Epub 2014 Aug 30.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heid elberg, Germany.

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http://genomemedicine.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13073-014-0066-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254427PMC
December 2014

PRC2 loss amplifies Ras signaling in cancer.

Nat Genet 2014 Nov;46(11):1154-5

Division of Epigenomics and Cancer Risk Factors at the German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/ng.3124DOI Listing
November 2014

Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis.

Cell Stem Cell 2014 Oct 21;15(4):507-522. Epub 2014 Aug 21.

Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, Germany; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany; German Cancer Consortium (DKTK), 69120 Heidelberg, Germany. Electronic address:

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http://www.cell.com/cms/attachment/2035154136/2050496774/mmc
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http://www-huber.embl.de/pub/pdf/CabezasWallscheid2014.pdf
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S193459091400301
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http://dx.doi.org/10.1016/j.stem.2014.07.005DOI Listing
October 2014

Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer.

Cell Rep 2014 Aug 24;8(3):798-806. Epub 2014 Jul 24.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; The German Cancer Consortium, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.053DOI Listing
August 2014

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

Mol Cell 2014 Aug 31;55(4):604-14. Epub 2014 Jul 31.

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; The German Cancer Consortium, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.06.031DOI Listing
August 2014

MGMT testing--the challenges for biomarker-based glioma treatment.

Nat Rev Neurol 2014 Jul 10;10(7):372-85. Epub 2014 Jun 10.

Department of Neuropathology, Heinrich Heine University, Germany.

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http://dx.doi.org/10.1038/nrneurol.2014.100DOI Listing
July 2014

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.

Cancer Discov 2014 Mar 19;4(3):348-61. Epub 2013 Dec 19.

Divisions of 1Epigenomics and Cancer Risk Factors, 2Theoretical Bioinformatics, 3Biostatistics, and 4Molecular Genetics; 5Department of Translational Oncology, National Center for Tumor Diseases (NCT), The German Cancer Research Center (DKFZ); 6Department of Medicine V, University of Heidelberg, Heidelberg; 7Department of Medicine, University of Freiburg Medical Center, Freiburg; 8Department of Internal Medicine III, University of Ulm, Ulm; 9The German Cancer Consortium, Germany; 10Department of Medicine, University of California at San Diego Moores Cancer Center, La Jolla, California; and 11Division of Hematology, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134522PMC
March 2014

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.

J Clin Oncol 2014 Feb 30;32(6):548-56. Epub 2013 Dec 30.

Guido Marcucci, Pearlly Yan, Kati Maharry, David Frankhouser, Deedra Nicolet, Klaus H. Metzeler, Jessica Kohlschmidt, Krzysztof Mrózek, Yue-Zhong Wu, Donna Bucci, John P. Curfman, Susan P. Whitman, Ann-Kathrin Eisfeld, Jason H. Mendler, Sebastian Schwind, Heiko Becker, John C. Byrd, Ramiro Garzon, Michael A. Caligiuri, Stefano Volinia, and Clara D. Bloomfield, The Ohio State University Comprehensive Cancer Center; Ralf Bundschuh, The Ohio State University, Columbus, OH; Kati Maharry, Deedra Nicolet, and Jessica Kohlschmidt, Alliance for Clinical Trials in Oncology Statistics and Data Center, Mayo Clinic, Rochester, MN; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Maria R. Baer, Greenebaum Cancer Center, University of Maryland, Baltimore, MD; Meir Wetzler, Roswell Park Cancer Institute, Buffalo; Jonathan E. Kolitz, Monter Cancer Center, Lake Success, NY; Thomas H. Carter, University of Iowa, Iowa City, IA; Bayard L. Powell, The Comprehensive Cancer Center of Wake Forest University, Winston-Salem, NC; Richard M. Stone, Dana-Farber Cancer Institute, Boston, MA; Constance Bär and Christoph Plass, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1200/JCO.2013.50.6337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918538PMC
February 2014

Recurrent H3.3 alterations in childhood tumors.

Nat Genet 2013 Dec;45(12):1413-4

Division of Epigenomics and Cancer Risk Factors at the German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/ng.2832DOI Listing
December 2013

Loss of DNMT1o disrupts imprinted X chromosome inactivation and accentuates placental defects in females.

PLoS Genet 2013 Nov 21;9(11):e1003873. Epub 2013 Nov 21.

Departments of Pharmacology & Therapeutics, Pediatrics and Human Genetics, Research Institute at The Montreal Children's Hospital of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1003873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836718PMC
November 2013

Promoter DNA methylation regulates progranulin expression and is altered in FTLD.

Acta Neuropathol Commun 2013 May 13;1:16. Epub 2013 May 13.

German Center for Neurodegenerative Diseases (DZNE), University of Munich, Schillerstr, 44, Munich 80336, Germany.

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http://dx.doi.org/10.1186/2051-5960-1-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893557PMC
May 2013