Christoph Hock

Christoph Hock

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Christoph Hock

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Increased cerebral blood volume in small arterial vessels is a correlate of amyloid-β-related cognitive decline.

Neurobiol Aging 2019 04 10;76:181-193. Epub 2019 Jan 10.

Institute for Regenerative Medicine (IREM), University of Zurich, Schlieren, Switzerland; Hospital for Psychogeriatric Medicine, Psychiatric University Hospital Zurich (PUK), Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438210PMC
April 2019

Low cortical iron and high entorhinal cortex volume promote cognitive functioning in the oldest-old.

Neurobiol Aging 2018 04 20;64:68-75. Epub 2017 Dec 20.

Institute for Regenerative Medicine (IREM), University of Zürich, Zürich, Switzerland; Hospital for Psychogeriatric Medicine, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820223PMC
April 2018

Brain amyloid burden and cerebrovascular disease are synergistically associated with neurometabolism in cognitively unimpaired older adults.

Neurobiol Aging 2018 03 12;63:152-161. Epub 2017 Dec 12.

Institute for Regenerative Medicine, University of Zurich, Schlieren, Switzerland; Hospital for Psychogeriatric Medicine, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.004DOI Listing
March 2018

Oxidative stress and altered mitochondrial protein expression in the absence of amyloid-β and tau pathology in iPSC-derived neurons from sporadic Alzheimer's disease patients.

Stem Cell Res 2018 03 28;27:121-130. Epub 2018 Jan 28.

University of Zurich, Institute for Regenerative Medicine, Schlieren, Switzerland; University of Zurich, Neuroscience Center Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.01.019DOI Listing
March 2018

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.

Am J Pathol 2017 Jun 11;187(6):1399-1412. Epub 2017 Apr 11.

Alzheimer's Disease Research Laboratory, Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455060PMC
June 2017

Microstructural Integrity of Hippocampal Subregions Is Impaired after Mild Traumatic Brain Injury.

J Neurotrauma 2017 04 2;34(7):1402-1411. Epub 2016 Dec 2.

2 Cognitive Neuroscience Unit, Montreal Neurological Institute , Montreal, Quebec, Canada .

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http://dx.doi.org/10.1089/neu.2016.4591DOI Listing
April 2017

The last phase of life with dementia in Swiss nursing homes: the study protocol of the longitudinal and prospective ZULIDAD study.

BMC Palliat Care 2016 Aug 24;15(1):80. Epub 2016 Aug 24.

University Research Priority Program "Dynamics of Healthy Aging", University of Zurich, Andreasstrasse 15, 8050, Zurich, Switzerland.

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http://dx.doi.org/10.1186/s12904-016-0151-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997715PMC
August 2016

Strong Impact of Smoking on Multimorbidity and Cardiovascular Risk Among Human Immunodeficiency Virus-Infected Individuals in Comparison With the General Population.

Authors:
Barbara Hasse Philip E Tarr Pedro Marques-Vidal Gerard Waeber Martin Preisig Vincent Mooser Fabio Valeri Sima Djalali Rauch Andri Enos Bernasconi Alexandra Calmy Matthias Cavassini Pietro Vernazza Manuel Battegay Rainer Weber Oliver Senn Peter Vollenweider Bruno Ledergerber V Aubert J Barth M Battegay E Bernasconi J Böni H C Bucher C Burton-Jeangros A Calmy M Cavassini M Egger L Elzi J Fehr J Fellay H Furrer C A Fux M Gorgievski H Günthard D Haerry B Hasse H H Hirsch I Hösli C Kahlert L Kaiser O Keiser T Klimkait R Kouyos H Kovari B Ledergerber G Martinetti B Martinez de Tejada K Metzner N Müller D Nadal G Pantaleo A Rauch S Regenass M Rickenbach C Rudin F Schöni-Affolter P Schmid D Schultze J Schüpbach R Speck C Staehelin P Tarr A Telenti A Trkola P Vernazza R Weber S Yerly Aubry Jean-Michel Bochud Murielle Gaspoz Jean Michel Hock Christoph Lüscher Thomas Marques Vidal Pedro Mooser Vincent Paccaud Fred Preisig Martin Vollenweider Peter Von Känel Roland Vladeta Aidacic Waeber Gerard Beriger Jürg Bertschi Markus Bhend Heinz Büchi Martin Bürke Hans-Ulrich Bugmann Ivo Cadisch Reto Charles Isabelle Chmiel Corinne Djalali Sima Duner Peter Erni Simone Forster Andrea Frei Markus Frey Claudius Frey Jakob Gibreil Musa Ali Günthard Matthias Haller Denis Hanselmann Marcel Häuptli Walter Heininger Simon Huber Felix Hufschmid Paul Kaiser Eva Kaplan Vladimir Klaus Daniel Koch Stephan Köstner Beat Kuster Benedict Kuster Heidi Ladan Vesna Lauffer Giovanni Leibundgut Hans Werner Luchsinger Phillippe Lüscher Severin Maier Christoph Martin Jürgen Meli Damian Messerli Werner Morger Titus Navarro Valentina Rizzi Jakob Rosemann Thomas Sajdl Hana Schindelek Frank Schlatter Georg Senn Oliver Somaini Pietro Staeger Jacques Staehelin Alfred Steinegger Alois Steurer Claudia Suter Othmar Truong The Phuoc Vecellio Marco Violi Alessandro Von Allmen René Waeckerlin Hans Weber Fritz Weber-Schär Johanna Widler Joseph Zoller Marco

Open Forum Infect Dis 2015 Sep 8;2(3):ofv108. Epub 2015 Jul 8.

Division of Infectious Diseases and Hospital Epidemiology , University of Zurich, University Hospital Zurich.

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http://dx.doi.org/10.1093/ofid/ofv108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536331PMC
September 2015

Prefrontal executive function associated coupling relates to Huntington's disease stage.

Cortex 2013 Nov-Dec;49(10):2661-73. Epub 2013 Jun 26.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Psychiatry Research and Psychogeriatric Medicine, University of Zürich, Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2013.05.015DOI Listing
July 2014

Intraindividual variability across cognitive tasks as a potential marker for prodromal Alzheimer's disease.

Front Aging Neurosci 2014 4;6:147. Epub 2014 Jul 4.

Division of Psychiatry Research and Psychogeriatric Medicine, University of Zurich, Zurich Switzerland.

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http://dx.doi.org/10.3389/fnagi.2014.00147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081834PMC
July 2014

Prefrontal brain network connectivity indicates degree of both schizophrenia risk and cognitive dysfunction.

Schizophr Bull 2014 May 18;40(3):653-64. Epub 2013 Jun 18.

*To whom correspondence should be addressed; Division of Psychiatry Research and Psychogeriatric Medicine, University of Zürich, Minervastrasse 145, CH-8032 Zürich, Switzerland; tel: +41-44-3891-453, fax: +41-44-3891-447, e-mail:

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http://dx.doi.org/10.1093/schbul/sbt077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984516PMC
May 2014

Quantification of subcortical gray-matter vascularization using 7 Tesla time-of-flight angiography.

Brain Behav 2013 Sep 14;3(5):515-8. Epub 2013 Jul 14.

Division of Psychiatry Research and Psychogeriatric Medicine, University of Zürich Zürich, Switzerland.

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http://dx.doi.org/10.1002/brb3.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869979PMC
September 2013

Superresolution imaging of amyloid fibrils with binding-activated probes.

ACS Chem Neurosci 2013 Jul 22;4(7):1057-61. Epub 2013 Apr 22.

Cell Biology and Biophysics, EMBL Heidelberg, Meyerhofstrasse 1, Heidelberg, Germany.

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http://dx.doi.org/10.1021/cn400091mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715833PMC
July 2013

Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury.

Eur Heart J 2013 Jan 24;34(2):96-103. Epub 2012 Sep 24.

Cardiovascular Research, Institute of Physiology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

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http://dx.doi.org/10.1093/eurheartj/ehs331DOI Listing
January 2013

Physical restraint use in nursing homes.

JAMA 2012 Sep;308(11):1091-2; author reply 1092

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http://dx.doi.org/10.1001/jama.2012.9400DOI Listing
September 2012

Transforming growth factor-beta inhibits the expression of clock genes.

Ann N Y Acad Sci 2012 Jul;1261:79-87

Department of Neurology, Inselspital, University Hospital Berne, University of Berne, Berne, Switzerland.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06640.xDOI Listing
July 2012

Associations between alcohol consumption and selected cytokines in a Swiss population-based sample (CoLaus study).

Atherosclerosis 2012 May 18;222(1):245-50. Epub 2012 Feb 18.

Institute of Social and Preventive Medicine (IUMSP), CHUV and Faculty of Biology and Medicine, 1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.02.011DOI Listing
May 2012

Volumes of lateral temporal and parietal structures distinguish between healthy aging, mild cognitive impairment, and Alzheimer's disease.

J Alzheimers Dis 2011 ;26(4):719-34

Division Neuropsychology, Institute of Psychology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3233/JAD-2011-101260DOI Listing
January 2012

A CYP46 T/C SNP modulates parahippocampal and hippocampal morphology in young subjects.

Neurobiol Aging 2011 Jun 3;32(6):1023-32. Epub 2009 Aug 3.

Division of Neuropsychology, Institute of Psychology, University of Zurich, Binzmühlestr. 14/25, 8050 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.neurobiolaging.2009.07.001DOI Listing
June 2011

The world of dementia beyond 2020.

J Am Geriatr Soc 2011 May 13;59(5):923-7. Epub 2011 Apr 13.

Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1532-5415.2011.03365.xDOI Listing
May 2011

Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology.

Brain 2010 May 31;133(Pt 5):1312-27. Epub 2010 Mar 31.

MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Massachusetts Alzheimer Disease Research Center, Harvard Medical School, Building 114, 16th Street, Charlestown, MA 02129-4404, USA.

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http://dx.doi.org/10.1093/brain/awq056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859150PMC
May 2010

Sexual dimorphism in the parietal substrate associated with visuospatial cognition independent of general intelligence.

J Cogn Neurosci 2010 Jan;22(1):139-55

Division of Neuropsychology, Institute of Psychology, University of Zurich, Binzmuehlestrasse 14/PO Box 25, 8050 Zurich, Switzerland.

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http://dx.doi.org/10.1162/jocn.2008.21175DOI Listing
January 2010

Abeta immunotherapy protects morphology and survival of adult-born neurons in doubly transgenic APP/PS1 mice.

J Neurosci 2009 Nov;29(45):14108-19

Division of Psychiatry Research, University of Zurich, 8008 Zurich, Switzerland.

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http://dx.doi.org/10.1523/JNEUROSCI.2055-09.2009DOI Listing
November 2009

Prion protein M129V polymorphism affects retrieval-related brain activity.

Neuropsychologia 2008 12;46(9):2389-402. Epub 2008 Mar 12.

Division of Psychiatry Research and Hospital for Psychogeriatric Medicine, University of Zurich, Minervastrasse 145, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.neuropsychologia.2008.03.002DOI Listing
September 2008

Targeting beta-amyloid pathology in Alzheimer's disease with Abeta immunotherapy.

Neurotherapeutics 2008 Jul;5(3):415-20

Division of Psychiatry Research, University of Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.nurt.2008.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084243PMC
July 2008

Radiation dosimetry and biodistribution of 11C-ABP688 measured in healthy volunteers.

Eur J Nucl Med Mol Imaging 2008 Apr 11;35(4):766-70. Epub 2007 Dec 11.

PET Center, Division of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00259-007-0638-4DOI Listing
April 2008

Genetic association study on colony-stimulating factor 1 in Alzheimer's disease.

Neurodegener Dis 2006 ;3(6):334-7

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1159/000097302DOI Listing
February 2007

Evidence of a genetic basis of Morgagni-Stewart-Morel syndrome. A case report of identical twins.

Neurodegener Dis 2005 ;2(2):56-60

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1159/000089284DOI Listing
January 2007

Enhanced brain activity may precede the diagnosis of Alzheimer's disease by 30 years.

Brain 2006 Nov 29;129(Pt 11):2908-22. Epub 2006 Sep 29.

Division of Psychiatry Research University of Zurich, Switzerland.

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http://dx.doi.org/10.1093/brain/awl266DOI Listing
November 2006

Clinical observations with AN-1792 using TAPIR analyses.

Neurodegener Dis 2005 ;2(5):273-6

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1159/000090368DOI Listing
September 2006

One month of human memory consolidation enhances retrieval-related hippocampal activity.

Hippocampus 2005 ;15(8):1026-40

Division of Psychiatry Research, University of Zurich, Switzerland.

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http://dx.doi.org/10.1002/hipo.20105DOI Listing
January 2006

The prion gene is associated with human long-term memory.

Hum Mol Genet 2005 Aug 29;14(15):2241-6. Epub 2005 Jun 29.

Division of Psychiatry Research, University of Zurich, 8032 Zurich, Switzerland.

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http://dx.doi.org/10.1093/hmg/ddi228DOI Listing
August 2005

Effects of memory consolidation on human hippocampal activity during retrieval.

Cortex 2005 Aug;41(4):486-98

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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August 2005

A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease.

J Clin Psychiatry 2005 Jul;66(7):940-7

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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July 2005

No association of a non-synonymous PLAU polymorphism with Alzheimer's disease and disease-related traits.

Am J Med Genet B Neuropsychiatr Genet 2005 Jan;132B(1):21-3

Division of Psychiatry Research, University of Zürich, Lengstrasse 31, 8029 Zürich, Switzerland.

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http://dx.doi.org/10.1002/ajmg.b.30103DOI Listing
January 2005

Low-dose cortisol for symptoms of posttraumatic stress disorder.

Am J Psychiatry 2004 Aug;161(8):1488-90

Division of Psychiatry Research, University of Zurich, Lenggstr. 31, 8029 Zurich, Switzerland.

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http://dx.doi.org/10.1176/appi.ajp.161.8.1488DOI Listing
August 2004

Glucocorticoid-related genetic susceptibility for Alzheimer's disease.

Hum Mol Genet 2004 Jan 28;13(1):47-52. Epub 2003 Oct 28.

Division of Psychiatry Research, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1093/hmg/ddg361DOI Listing
January 2004

A functional genetic variation of the 5-HT2a receptor affects human memory.

Nat Neurosci 2003 Nov 19;6(11):1141-2. Epub 2003 Oct 19.

Division of Psychiatry Research, University of Zürich, Lenggstr. 31, 8029 Zürich, Switzerland.

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http://dx.doi.org/10.1038/nn1146DOI Listing
November 2003

Interactive computer-training as a therapeutic tool in Alzheimer's disease.

Compr Psychiatry 2003 May-Jun;44(3):213-9

Department of Psychiatry, University Basle, Basle, Switzerland.

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http://dx.doi.org/10.1016/S0010-440X(03)00006-3DOI Listing
October 2003

Safety of injectable opioid maintenance treatment for heroin dependence.

Biol Psychiatry 2003 Oct;54(8):854-61

Center of Applied Technologies in Neuroscience-Basel, Psychiatric University Clinic of Basel, Wilhelm Klein-Strasse 27, 4025 Basel, Switzerland.

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October 2003

Functional neuroimaging predicts individual memory outcome after amygdalohippocampectomy.

Neuroreport 2003 Jul;14(9):1197-202

Division of Psychiatry Research, University of Zürich, Switzerland.

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http://dx.doi.org/10.1097/01.wnr.0000081865.45938.64DOI Listing
July 2003

Nonconscious formation and reactivation of semantic associations by way of the medial temporal lobe.

Neuropsychologia 2003 ;41(8):863-76

Division of Psychiatry Research, Psychiatric University Hospital, University of Zürich, Lenggstrasse 31, 8029 Zürich, Switzerland.

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June 2003

ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease.

Neurobiol Aging 2003 May-Jun;24(3):421-6

Division of Psychiatry Research, University of Zürich, August Forel Street 1, 8008, Zürich, Switzerland.

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April 2003

Biochemical aspects of dementias.

Authors:
Christoph Hock

Dialogues Clin Neurosci 2003 Mar;5(1):27-33

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181716PMC
March 2003

Glucocorticoid-induced impairment of declarative memory retrieval is associated with reduced blood flow in the medial temporal lobe.

Eur J Neurosci 2003 Mar;17(6):1296-302

Division of Psychiatry Research, University of Zürich, Lenggstr. 31, 8029 Zürich, Switzerland.

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March 2003

Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease.

Nat Med 2002 Nov 15;8(11):1270-5. Epub 2002 Oct 15.

Division of Psychiatry Research, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/nm783DOI Listing
November 2002

Decline in long-term circadian rest-activity cycle organization in a patient with dementia.

J Geriatr Psychiatry Neurol 2002 ;15(1):55-9

Centre for Chronobiology and Alzheimer's Research Group, Psychiatric University Clinic Basel, Switzerland.

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http://dx.doi.org/10.1177/089198870201500111DOI Listing
September 2002

Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation.

J Biol Chem 2002 Sep 14;277(36):33012-7. Epub 2002 Jun 14.

Division of Psychiatry Research, University of Zurich, August Forel Strasse 1, 8008 Zurich, Switzerland.

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http://dx.doi.org/10.1074/jbc.M203193200DOI Listing
September 2002

Biochemical markers of Alzheimer's disease: wish and reality.

Neurobiol Aging 2002 Jul-Aug;23(4):513-4

Division of Psychiatry Research, University of Zurich, Switzerland.

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July 2002

New aspects in the treatment of heroin dependence with special reference to neurobiological aspects.

Eur Psychiatry 2002 May;17(3):163-6

Department of Psychiatry, University of Basel, Wilhelm Klein-Strasse 27, CH-4025, Basel, Switzerland.

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May 2002