Christoph C Zielinski

Christoph C Zielinski

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Christoph C Zielinski

Publications by authors named "Christoph C Zielinski"

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How I treat cancer special issue.

ESMO Open 2019 1;4(Suppl 2):e000514. Epub 2019 May 1.

Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1136/esmoopen-2019-000514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555613PMC
May 2019

Saudi lung cancer management guidelines 2017: Improving lung cancer care in Saudi region.

Ann Thorac Med 2017 Oct-Dec;12(4):219-220

Department of Medicine I, Clinical Division of Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.4103/atm.ATM_225_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656940PMC
November 2017

Combining standard clinical blood values for improving survival prediction in patients with newly diagnosed brain metastases-development and validation of the LabBM score.

Neuro Oncol 2017 Sep;19(9):1255-1262

Department of Medicine I, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria; Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland; Biostatistics Division, German Cancer Research Center, Heidelberg, Germany; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria; Department of Radiotherapy, Medical University of Vienna, Vienna, Austria; Department of Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1093/neuonc/now290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570252PMC
September 2017

Educational video: the role of PD-L1 in the local tumour microenvironment.

ESMO Open 2016 1;1(6):e000137. Epub 2017 Feb 1.

Central European Cooperative Oncology Group (CECOG), Vienna, Austria.

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http://dx.doi.org/10.1136/esmoopen-2016-000137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548971PMC
February 2017

CSCO joins ESMO Open-Cancer Horizons.

ESMO Open 2016 18;1(5):e000120. Epub 2016 Nov 18.

Guangdong Lung Cancer Institute, Guangzhou, Guangdong, People's Republic of China; Chinese Society of Clinical Oncology (CSCO), Houston, Texas, USA.

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http://dx.doi.org/10.1136/esmoopen-2016-000120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133379PMC
November 2016

Sustained Response to Vemurafenib in a BRAF-Mutated Anaplastic Thyroid Carcinoma Patient.

Thyroid 2016 10 27;26(10):1515-1516. Epub 2016 Sep 27.

1 Department of Medicine I, Comprehensive Cancer Center Vienna; Medical University of Vienna , Vienna, Austria .

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http://dx.doi.org/10.1089/thy.2015.0575DOI Listing
October 2016

AIOM chooses as its official journal: a warm welcome from .

ESMO Open 2016 1;1(4):e000080. Epub 2016 Jul 1.

Reggio Emilia , Italy.

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http://dx.doi.org/10.1136/esmoopen-2016-000080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070276PMC
July 2016

Cancer immune cycle: a video introduction to the interaction between cancer and the immune system.

ESMO Open 2016 12;1(3):e000056. Epub 2016 Apr 12.

Central European Cooperative Oncology Group (CECOG) , Vienna , Austria.

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http://dx.doi.org/10.1136/esmoopen-2016-000056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070358PMC
April 2016

Descriptive statistical analysis of a real life cohort of 2419 patients with brain metastases of solid cancers.

ESMO Open 2016 16;1(2):e000024. Epub 2016 Mar 16.

Department of Medicine I, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1136/esmoopen-2015-000024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070252PMC
March 2016

and the future of oncology.

ESMO Open 2016 18;1(1):e000008. Epub 2016 Jan 18.

Department of Medicine I , Comprehensive Cancer Center, Medical University Vienna , Vienna , Austria.

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http://dx.doi.org/10.1136/esmoopen-2015-000008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070212PMC
January 2016

In vivo Tube Assay: An Optimised Protocol of the Directed in vivo Angiogenesis Assay by Implementing Immunohistochemistry.

J Vasc Res 2015 31;52(2):116-26. Epub 2015 Jul 31.

Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000434751DOI Listing
December 2015

Integrin beta-3 genetic variants and risk of venous thromboembolism in colorectal cancer patients.

Thromb Res 2015 Nov 28;136(5):865-9. Epub 2015 Aug 28.

Department of Internal Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.08.010DOI Listing
November 2015

Spectrum of gene mutations detected by next generation exome sequencing in brain metastases of lung adenocarcinoma.

Eur J Cancer 2015 Sep 8;51(13):1803-11. Epub 2015 Jul 8.

Department of Pathology, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Central Nervous System Unit (CCC-CNS), Medical University of Vienna, Austria.

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http://dx.doi.org/10.1016/j.ejca.2015.06.107DOI Listing
September 2015

Effects of cilengitide in osteoclast maturation and behavior.

Exp Cell Res 2015 Sep 21;337(1):68-75. Epub 2015 Jul 21.

Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2015.07.018DOI Listing
September 2015

Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma.

Neuro Oncol 2015 Aug 29;17(8):1064-75. Epub 2014 Oct 29.

Institute of Neurology, Medical University of Vienna, Vienna, Austria (A.S.B., G.R., A.W., J.A.H.); Department of Medicine I, Medical University of Vienna, Vienna, Austria (A.S.B., O.R., M.F., A.B., C.C.Z., C.M., M.P.); Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria (A.S.B., B.K., G.W., O.R., G.R., A.W., K.D., M.F., A.B., C.C.Z., C.M., J.A.H., M.P.); Department of Neurosurgery, Medical University of Vienna, Vienna, Austria (B.K., G.W.); Department of Radiotherapy, Medical University of Vienna, Vienna, Austria (K.D.); Department of Neurology, University Hospital Zurich, Zurich, Switzerland (M.W.); Laboratory of Brain Tumor Biology and Genetics, Service of Neurosurgery, Department of Clinical Neurosciences, University Hospital Lausanne (CHUV), Lausanne, Switzerland (S.K., M.E.H.); Neurology Clinic and National Center for Tumor Disease, University of Heidelberg, Heidelberg, Germany (W.W.); Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany (W.W.).

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http://dx.doi.org/10.1093/neuonc/nou307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490866PMC
August 2015

Translating the molecular analysis of cancer biology into therapeutic concepts.

Cancer Biomark 2014 ;14(2-3):87-91

Department of Medicine, Clinical Division of Oncology, Comprehensive Cancer Center of the Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3233/CBM-130382DOI Listing
July 2015

Outcome of chemotherapy extravasation in a large patient series using a standardised management protocol.

Support Care Cancer 2015 Jun 30;23(6):1741-8. Epub 2014 Nov 30.

Department of Medicine I, Clinical Division of Oncology, Comprehensive Cancer Center of the Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00520-014-2535-2DOI Listing
June 2015

Indocyanine green video angiography predicts outcome of extravasation injuries.

PLoS One 2014 21;9(8):e103649. Epub 2014 Aug 21.

Department of Medicine I, Clinical Division of Oncology, Comprehensive Cancer Center of the Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103649PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140719PMC
May 2015

Prominin-1 (CD133, AC133) and dipeptidyl-peptidase IV (CD26) are indicators of infinitive growth in colon cancer cells.

Am J Cancer Res 2015 15;5(2):560-74. Epub 2015 Jan 15.

Ludwig Boltzmann Cluster Oncology, Medical University of Vienna Waehringer Guertel 18-20, A-1090 Vienna, Austria ; Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396035PMC
May 2015

Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases.

Neuropathol Appl Neurobiol 2015 Feb;41(2):e41-55

Institute of Neurology, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center CNS Tumors Unit, Medical University of Vienna, Vienna, Austria; Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/nan.12185DOI Listing
February 2015

Novel agents have a significant impact on survival of patients with multiple myeloma.

Wien Klin Wochenschr 2015 Feb 22;127(3-4):92-7. Epub 2015 Jan 22.

Department of Medicine I, Clinical Division of Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-014-0605-6DOI Listing
February 2015

A phase I study of MEDI4736, NNT-PD-L1 antibody in patients with advanced solid tumors.

Transl Lung Cancer Res 2014 Dec;3(6):406-7

1 Clinical Division of Oncology and Chairman, Department of Medicine I, 2 Comprehensive Cancer Center, Medical University Vienna, General Hospital, Vienna, Austria ; 3 Central European Cooperative Oncology Group, Vienna, Austria.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2014.08.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367668PMC
December 2014

Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients.

Breast 2014 Oct 10;23(5):637-43. Epub 2014 Jul 10.

Comprehensive Cancer Center Vienna, Medical University of Vienna, Austria; Department of Pathology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1016/j.breast.2014.06.011DOI Listing
October 2014

Baseline carcinoembryonic antigen (CEA) serum levels predict bevacizumab-based treatment response in metastatic colorectal cancer.

Cancer Sci 2014 Aug 31;105(8):996-1001. Epub 2014 Jul 31.

Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1111/cas.12451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317865PMC
August 2014

High-level ERBB2 gene amplification is associated with a particularly short time-to-metastasis, but results in a high rate of complete response once trastuzumab-based therapy is offered in the metastatic setting.

Int J Cancer 2014 Jul 28;135(1):224-31. Epub 2014 Jan 28.

Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/ijc.28660DOI Listing
July 2014

Alleviation of brain edema and restoration of functional independence by bevacizumab in brain-metastatic breast cancer: a case report.

Breast Care (Basel) 2014 May;9(2):134-6

Department of Medicine I, Medical University of Vienna, Austria ; Comprehensive Cancer Center, CNS Tumors Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000360930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038309PMC
May 2014

Rituximab plus bendamustine is active in pretreated patients with extragastric marginal zone B cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma).

Ann Hematol 2014 Feb 8;93(2):249-53. Epub 2013 Aug 8.

Clinical Division of Oncology, Department of Internal Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria.

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http://dx.doi.org/10.1007/s00277-013-1865-3DOI Listing
February 2014

CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior.

Mol Cancer 2013 Dec 21;12:169. Epub 2013 Dec 21.

Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1186/1476-4598-12-169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879186PMC
December 2013

Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis.

Cancer Res 2013 Nov 11;73(22):6584-96. Epub 2013 Oct 11.

Authors' Affiliations: Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center; Institute of Clinical Pathology; Department of Vascular Biology and Thrombosis Research, Centre for Bio-Molecular Medicine and Pharmacology, Medical University of Vienna, Vienna, Austria; and Tumor Immunology Laboratory, LIFE-Center, Klinikum Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0123DOI Listing
November 2013

Impact of HER-2-targeted therapy on overall survival in patients with HER-2 positive metastatic breast cancer.

Breast J 2013 Mar-Apr;19(2):149-55. Epub 2013 Jan 27.

Clinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1111/tbj.12070
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http://dx.doi.org/10.1111/tbj.12070DOI Listing
September 2013

"Il flauto magico" still works: Mozart's secret of ventilation.

Multidiscip Respir Med 2013 Mar 19;8(1):23. Epub 2013 Mar 19.

Medical University of Vienna, Department of Internal Medicine 1, Division of Palliative Care, Waehringer Guertel 18-20, Vienna 1090, Austria.

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http://dx.doi.org/10.1186/2049-6958-8-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608996PMC
March 2013

Vaccination for the prevention and treatment of breast cancer with special focus on Her-2/neu peptide vaccines.

Breast Cancer Res Treat 2013 Feb 23;138(1):1-12. Epub 2013 Jan 23.

Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Immunology & Infectiology, Medical University of Vienna, Kinderspitalgasse 15, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s10549-013-2410-8DOI Listing
February 2013

The urokinase receptor (CD87) represents a central mediator of growth factor-induced endothelial cell migration.

Thromb Haemost 2012 Aug 10;108(2):357-66. Epub 2012 Jul 10.

Clinical Division of Oncology, Department of Medicine I and Comprehensive Cancer Center Vienna, Medical University Vienna, Austria.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH11-12-0868
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http://dx.doi.org/10.1160/TH11-12-0868DOI Listing
August 2012

Her-2/neu gene amplification and over-expression in stomach and esophageal adenocarcinoma: from pathology to treatment.

Crit Rev Oncol Hematol 2012 Jun 23;82(3):310-22. Epub 2011 Jul 23.

Department of Pathology, General Hospital - Medical University of Vienna, Austria.

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http://dx.doi.org/10.1016/j.critrevonc.2011.06.003DOI Listing
June 2012

Pilot study on sex hormone levels and fertility in women with malignant gliomas.

J Neurooncol 2012 Apr 20;107(2):387-94. Epub 2011 Nov 20.

Department of Medicine I, Division of Oncology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s11060-011-0761-8DOI Listing
April 2012

Angiogenesis in cancer: Anti-VEGF escape mechanisms.

Transl Lung Cancer Res 2012 Mar;1(1):14-25

Medical University of Vienna, Comprehensive Cancer Center Vienna, Department of Medicine I, Austria.

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http://dx.doi.org/10.3978/j.issn.2218-6751.2011.11.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367591PMC
March 2012

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

Breast Cancer Res Treat 2011 Sep 3;129(2):387-400. Epub 2010 Nov 3.

Signaling Networks Program, Division of Oncology, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10549-010-1232-1DOI Listing
September 2011

Hypothyroidism in patients with renal cell carcinoma: blessing or curse?

Cancer 2011 Feb 15;117(3):534-44. Epub 2010 Sep 15.

Clinical Division of Oncology, Department of Medicine I and Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/cncr.25422DOI Listing
February 2011

Neoplastic stem cells: current concepts and clinical perspectives.

Crit Rev Oncol Hematol 2010 Nov 25;76(2):79-98. Epub 2010 Feb 25.

Bone Marrow Transplantation Unit, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.critrevonc.2010.01.001DOI Listing
November 2010

Defining risk status in the first-line treatment of metastatic renal cell carcinoma.

J Cancer Res Clin Oncol 2010 Jul 8;136(7):961-8. Epub 2010 May 8.

Department of Medicine I, Clinical Division of Oncology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://link.springer.com/10.1007/s00432-010-0901-0
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http://dx.doi.org/10.1007/s00432-010-0901-0DOI Listing
July 2010

Capecitabine and Vinorelbine as an All-Oral Chemotherapy in HER2-Negative Locally Advanced and Metastatic Breast Cancer.

Breast Care (Basel) 2010 27;5(3):158-162. Epub 2010 May 27.

Universitätsklinik für Innere Medizin I, Klinische Abteilung für Onkologie, Medizinische Universität Wien, Österreich.

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http://dx.doi.org/000314214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931054PMC
May 2010

Triple-negative breast cancer.

Wien Med Wochenschr 2010 Apr;160(7-8):174-81

Clinical Division of Oncology, Department of Medicine 1 and Cancer Centre, Medical University of Vienna, Vienna, Austria.

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http://link.springer.com/10.1007/s10354-010-0773-6
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http://dx.doi.org/10.1007/s10354-010-0773-6DOI Listing
April 2010

Lung cancer: from single-gene methylation to methylome profiling.

Cancer Metastasis Rev 2010 Mar;29(1):95-107

Department of Medicine I, Clinical Division of Oncology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10555-010-9203-xDOI Listing
March 2010

Unilateral face swelling as first manifestation of metastatic pancreatic cancer: case report and review of the literature.

Wien Klin Wochenschr 2008 ;120(21-22):693-6

Department of Internal Medicine I and Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-008-1084-4DOI Listing
February 2010

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells.

Biochem Biophys Res Commun 2009 Jul 23;385(3):454-9. Epub 2009 May 23.

Signaling Networks Program, Department of Medicine I, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.bbrc.2009.05.085DOI Listing
July 2009

Synergistic effect of Sorafenib and Sunitinib with Enzastaurin, a selective protein kinase C inhibitor in renal cell carcinoma cell lines.

Cancer Lett 2009 May 25;277(2):218-26. Epub 2009 Jan 25.

Clinical Division of Oncology, Department of Medicine I, Medical University Vienna, Waehringer Guertel 18-20, Vienna, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S030438350800945
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http://dx.doi.org/10.1016/j.canlet.2008.12.013DOI Listing
May 2009

Novel agents for renal cell carcinoma require novel selection paradigms to optimise first-line therapy.

Cancer Treat Rev 2009 May 15;35(3):289-96. Epub 2009 Feb 15.

Department of Medicine I and Cancer Center, Clinical Division of Oncology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.ctrv.2009.01.004DOI Listing
May 2009

A phase II study of bortezomib in patients with MALT lymphoma.

Haematologica 2009 May 31;94(5):738-42. Epub 2009 Mar 31.

Department of Internal Medicine I, Division of Oncology, Medical University Vienna, Waehringer Guertel 18-20, Vienna, Austria.

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http://dx.doi.org/10.3324/haematol.2008.001537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675689PMC
May 2009

Management of cardiac adverse events occurring with sunitinib treatment.

Anticancer Res 2009 May;29(5):1627-9

Medical University of Vienna, Department of Medicine I and Cancer Center, Clinical Division of Oncology, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

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May 2009

Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma.

J Clin Oncol 2008 Nov 6;26(32):5204-12. Epub 2008 Oct 6.

Clinical Division of Oncology, Department of Medicine I and Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1200/JCO.2007.15.6331DOI Listing
November 2008

Factors influencing the time to development of brain metastases in breast cancer.

Breast 2008 Oct 19;17(5):512-6. Epub 2008 May 19.

Department of Radiotherapy and Radiobiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.breast.2008.03.008DOI Listing
October 2008

[Use of trastuzumab in the therapy of breast cancer].

Ther Umsch 2008 Apr;65(4):217-22

Klinische Abteilung für Onkologie, Universitätsklinik für Innere Medizin I, Medizinische Universität Wien, Währinger Gürtel 18-20, Vienna.

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http://dx.doi.org/10.1024/0040-5930.65.4.217DOI Listing
April 2008