Publications by authors named "Christoph Borner"

56Publications

Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins.

Cell Death Discov 2020 18;6:90. Epub 2020 Sep 18.

Department of Neurobiology, School of Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, 69978 Israel.

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September 2020

Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner.

Autophagy 2020 Oct 6:1-17. Epub 2020 Oct 6.

Institute of Molecular Medicine and Cell Research, Faculty of Medicine, Albert Ludwigs University of Freiburg , Freiburg, Germany.

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October 2020

Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells.

Commun Biol 2020 May 19;3(1):246. Epub 2020 May 19.

Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Stefan Meier Strasse 17, 79104, Freiburg, Germany.

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May 2020

Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress.

Metallomics 2018 12;10(12):1743-1754

Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Química Analítica y Fisicoquímica, Cátedra de Química General e Inorgánica, Junin 956, C1113AAD, Buenos Aires, Argentina.

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December 2018

TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation.

Cell Death Dis 2018 09 5;9(9):909. Epub 2018 Sep 5.

Institute of Molecular Medicine and Cell Research, Faculty of Medicine, Albert Ludwigs University Freiburg, Stefan Meier Strasse 17, D-79104, Freiburg, Germany.

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September 2018

Requirement of GSK-3 for PUMA induction upon loss of pro-survival PI3K signaling.

Cell Death Dis 2018 05 1;9(5):470. Epub 2018 May 1.

Institute of Molecular Medicine and Cell Research, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.

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May 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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March 2018

Role of apoptosis in the development of autosomal dominant polycystic kidney disease (ADPKD).

Cell Tissue Res 2017 07 30;369(1):27-39. Epub 2017 May 30.

Institute of Molecular Medicine and Cell Research, Albert Ludwigs University of Freiburg, Stefan Meier Strasse 17, 79104, Freiburg, Germany.

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July 2017

HSV-1-induced activation of NF-κB protects U937 monocytic cells against both virus replication and apoptosis.

Cell Death Dis 2016 09 1;7(9):e2354. Epub 2016 Sep 1.

Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Messina 98166, Italy.

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September 2016

SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.

EMBO Rep 2016 10 25;17(10):1485-1497. Epub 2016 Jul 25.

Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Freiburg, Germany Spemann Graduate School of Biology and Medicine (SGBM), Albert-Ludwigs-University of Freiburg, Freiburg, Germany BIOSS, Centre for Biological Signaling Studies, Freiburg, Germany

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October 2016

Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.

PLoS One 2015 1;10(6):e0126645. Epub 2015 Jun 1.

Institute of Molecular Medicine and Cell Research, Albert Ludwigs University of Freiburg, Stefan Meier Strasse 17, D-79104, Freiburg, Germany; Spemann Graduate School of Biology and Medicine (SGBM), Albert Ludwigs University of Freiburg, Albertstrasse 19a, D-79104, Freiburg, Germany; BIOSS, Centre for Biological Signaling Studies, Hebelstrasse 2, D-79104, Freiburg, Germany.

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February 2016

How do viruses control mitochondria-mediated apoptosis?

Virus Res 2015 Nov 1;209:45-55. Epub 2015 Mar 1.

Institute of Molecular Medicine, Albert Ludwigs University Freiburg, Germany; Spemann Graduate School of Biology and Medicine (SGBM), Albert Ludwigs University Freiburg, Germany; Centre for Biological Signaling Studies (BIOSS), Albert Ludwigs University Freiburg, Germany. Electronic address:

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November 2015

Interleukin-1β enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes.

PLoS One 2014 31;9(12):e115603. Epub 2014 Dec 31.

Department of Pharmaceutical Biology and Biotechnology, Albert Ludwigs University Freiburg, Freiburg, Germany; Spemann Graduate School of Biology and Medicine (SGBM), Albert Ludwigs University Freiburg, Freiburg, Germany.

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September 2015

Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release.

Nucleus 2014 ;5(6):527-41

a Department of Neurobiology; George S. Wise Faculty of Life Sciences ; Tel Aviv University ; Ramat Aviv , Israel.

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September 2015

A novel mitochondrial MAVS/Caspase-8 platform links RNA virus-induced innate antiviral signaling to Bax/Bak-independent apoptosis.

J Immunol 2014 Feb 3;192(3):1171-83. Epub 2014 Jan 3.

Institute of Molecular Medicine and Cell Research, Albert Ludwigs University Freiburg, D-79104 Freiburg, Germany;

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February 2014

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Arch Toxicol 2013 Aug 23;87(8):1315-530. Epub 2013 Aug 23.

Leibniz Research Centre for Working Environment and Human Factors (IFADO), 44139, Dortmund, Germany.

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August 2013

TNFα-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation.

J Cell Sci 2013 Sep 20;126(Pt 17):4015-25. Epub 2013 Jun 20.

Institute of Molecular Medicine and Cell Research (ZBMZ), Albert Ludwigs University Freiburg, Stefan Meier Strasse 17, D-79104 Freiburg, Germany.

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September 2013

Non-canonical function of Bax in stress-induced nuclear protein redistribution.

Cell Mol Life Sci 2013 Aug 9;70(16):3013-27. Epub 2013 Mar 9.

Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel.

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August 2013

Cytosolic Bax: does it require binding proteins to keep its pro-apoptotic activity in check?

J Biol Chem 2012 Mar 25;287(12):9112-27. Epub 2012 Jan 25.

Institute of Molecular Medicine and Cell Research, Center for Biochemistry and Molecular Cell Research, Albert Ludwigs University, Freiburg, Germany.

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March 2012

Integration of Boolean models exemplified on hepatocyte signal transduction.

Brief Bioinform 2012 May 20;13(3):365-76. Epub 2011 Oct 20.

Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany.

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May 2012

Nuclear proteins acting on mitochondria.

Biochim Biophys Acta 2011 Apr 2;1813(4):584-96. Epub 2010 Dec 2.

Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, 69978 Ramat Aviv, Israel.

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April 2011

Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner.

Hepatology 2011 Jan 24;53(1):282-92. Epub 2010 Sep 24.

Department of Pharmaceutical Biology and Biotechnology, Albert Ludwigs University of Freiburg, Freiburg, Germany.

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January 2011

Non-caspase proteases: triggers or amplifiers of apoptosis?

Cell Mol Life Sci 2010 May 19;67(10):1607-18. Epub 2010 Feb 19.

Institute of Molecular Medicine and Cell Research (ZBMZ), Albert Ludwigs University Freiburg, Stefan Meier Str. 17, 79104, Freiburg, Germany.

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May 2010

ON/OFF and beyond--a boolean model of apoptosis.

PLoS Comput Biol 2009 Dec 11;5(12):e1000595. Epub 2009 Dec 11.

Institute for System Dynamics, University of Stuttgart, Stuttgart, Germany.

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December 2009

XIAP discriminates between type I and type II FAS-induced apoptosis.

Nature 2009 Aug 22;460(7258):1035-9. Epub 2009 Jul 22.

The Walter and Eliza Hall Institute of Medical Research, Melbourne University, Parkville, Victoria 3050, Australia.

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August 2009

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.

Nat Immunol 2009 Mar 1;10(3):257-65. Epub 2009 Feb 1.

Waisman Center for Developmental Disabilities, the Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA.

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March 2009

Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins.

J Mol Biol 2007 Apr 12;368(1):44-54. Epub 2007 Jan 12.

Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, Universität Freiburg, Hermann-Herder-Strasse 7, D-79104 Freiburg, Germany.

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April 2007

Role of Bcl-2 expression for productive herpes simplex virus 2 replication.

Virology 2006 Dec 5-20;356(1-2):136-46. Epub 2006 Sep 6.

Department of Microbiological, Genetic and Molecular Sciences, University of Messina, Salita Sperone 31, 98166 Messina, Italy.

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January 2007

RIP death domain structural interactions implicated in TNF-mediated proliferation and survival.

Proteins 2006 May;63(3):413-23

Department of Bioinformatics, Biocenter, Am Hubland, University of Wuerzburg, Wuerzburg, Germany.

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May 2006

Volatile anesthetics induce caspase-dependent, mitochondria-mediated apoptosis in human T lymphocytes in vitro.

Anesthesiology 2005 Jun;102(6):1147-57

Division of Experimental Anesthesiology, Institute of Molecular Medicine, University Hospital, Hugstetterstrasse 55, D-79106 Freiburg, Germany.

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June 2005

Bcl-x(S) induces an NGF-inhibitable cytochrome c release.

Exp Cell Res 2004 Jul;297(2):392-403

Department of Neurobiochemistry, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.

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July 2004

Conformational control of Bax localization and apoptotic activity by Pro168.

J Cell Biol 2004 Mar 22;164(7):1021-32. Epub 2004 Mar 22.

Institute of Molecular Medicine and Cell Research, Center for Biochemistry and Molecular Cell Research, Albert-Ludwigs-University Freiburg, Stefan-Meier Strasse 17, D-79104 Freiburg, Germany.

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March 2004

Bcl-2 family members: integrators of survival and death signals in physiology and pathology [corrected].

Biochim Biophys Acta 2004 Mar;1644(2-3):95-105

Institute for Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, Breisachertstrasse 66, D-79106 Fribourg, Germany.

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March 2004

Bcl-w(edding) with mitochondria.

Trends Cell Biol 2004 Jan;14(1):8-12

Institute of Molecular Medicine and Cell Research, Zentrale Klinische Forschung (ZKF), Albert-Ludwigs-University Freiburg, Breisacherstrasse 66, 79106 Freiburg, Germany

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January 2004

Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis.

Acta Neuropathol 2003 May 12;105(5):499-507. Epub 2003 Feb 12.

Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3010 Bern, Switzerland.

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May 2003

Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane.

J Cell Biol 2003 Jan 6;160(1):53-64. Epub 2003 Jan 6.

Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University Freiburg, D-79106 Freiburg, Germany.

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January 2003

The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions.

Authors:
Christoph Borner

Mol Immunol 2003 Jan;39(11):615-47

Institute of Molecular Medicine and Cell Research, Albert-Ludwigs-University, Freiburg, Germany.

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January 2003