Christine S Chow

Christine S Chow

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Christine S Chow

Christine S Chow

Publications by authors named "Christine S Chow"

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Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites.

Bioorg Med Chem 2019 Sep 13:115121. Epub 2019 Sep 13.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.115121DOI Listing
September 2019

Amino acid-linked platinum(II) compounds: non-canonical nucleoside preferences and influence on glycosidic bond stabilities.

J Biol Inorg Chem 2019 Jul 29. Epub 2019 Jul 29.

Department of Chemistry, Wayne State University, Detroit, MI, 48202, USA.

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http://dx.doi.org/10.1007/s00775-019-01693-yDOI Listing
July 2019

The use of electrospray ionization mass spectrometry to monitor RNA-ligand interactions.

Methods Enzymol 2019 27;623:315-337. Epub 2019 May 27.

Wayne State University, Detroit, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.05.013DOI Listing
May 2019

Chemical probing for examining the structure of modified RNAs and ligand binding to RNA.

Methods 2019 03 2;156:110-120. Epub 2018 Nov 2.

Department of Chemistry, 5101 Cass Ave., Wayne State University, Detroit, MI 48202, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10462023183020
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http://dx.doi.org/10.1016/j.ymeth.2018.10.015DOI Listing
March 2019

Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling.

Biochemistry 2018 02 5;57(5):772-780. Epub 2018 Jan 5.

Department of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.

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http://pubs.acs.org/doi/10.1021/acs.biochem.7b01083
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http://dx.doi.org/10.1021/acs.biochem.7b01083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856478PMC
February 2018

Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes.

Org Biomol Chem 2017 Oct;15(40):8535-8543

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1039/c7ob02147jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663508PMC
October 2017

The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes.

Bioorg Med Chem 2016 09 25;24(18):4486-4491. Epub 2016 Jul 25.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992606PMC
September 2016

Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions.

Acc Chem Res 2016 05 11;49(5):893-901. Epub 2016 Apr 11.

Department of Chemistry, Wayne State University , Detroit, Michigan 48202, United States.

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http://dx.doi.org/10.1021/acs.accounts.6b00014DOI Listing
May 2016

Modulation of conformational changes in helix 69 mutants by pseudouridine modifications.

Biophys Chem 2015 May-Jun;200-201:48-55. Epub 2015 Mar 11.

Department of Chemistry, Wayne State University, Detroit, MI 48202, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bpc.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414897PMC
January 2016

Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins.

Int J Mol Sci 2015 Sep 7;16(9):21392-409. Epub 2015 Sep 7.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.3390/ijms160921392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613259PMC
September 2015

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations.

Nucleic Acids Res 2014 Apr 26;42(6):3971-81. Epub 2013 Dec 26.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1093/nar/gkt1329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973299PMC
April 2014

Amino acid-linked platinum(II) analogues have altered specificity for RNA compared to cisplatin.

Chem Commun (Camb) 2014 Apr 13;50(30):3918-20. Epub 2014 Jan 13.

Department of Chemistry, Wayne State University, 5101 Cass Ave., Detroit, MI 48202, USA.

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http://dx.doi.org/10.1039/c3cc49035aDOI Listing
April 2014

Probing the stabilizing effects of modified nucleotides in the bacterial decoding region of 16S ribosomal RNA.

Bioorg Med Chem 2013 May 21;21(10):2720-6. Epub 2013 Mar 21.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2013.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683315PMC
May 2013

Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA.

Bioorg Med Chem 2013 Mar 10;21(5):1240-7. Epub 2013 Jan 10.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2012.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594512PMC
March 2013

Ligand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence.

Angew Chem Int Ed Engl 2012 Nov 24;51(48):12095-8. Epub 2012 Oct 24.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1002/anie.201206000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741684PMC
November 2012

Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly.

ACS Chem Biol 2012 May 24;7(5):871-8. Epub 2012 Feb 24.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1021/cb200497qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356499PMC
May 2012

Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and human.

Biopolymers 2012 Feb 19;97(2):94-106. Epub 2011 Aug 19.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1002/bip.21706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269404PMC
February 2012

Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNA(Lys).

Chem Biol 2011 Jul;18(7):928-36

Institute of Applied Physics and Center for Functional Nanostructures, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.

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http://dx.doi.org/10.1016/j.chembiol.2011.03.016DOI Listing
July 2011

Probing conformational states of modified helix 69 in 50S ribosomes.

J Am Chem Soc 2011 Jun 16;133(22):8396-9. Epub 2011 May 16.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/ja2005658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106124PMC
June 2011

A modified fluorescent intercalator displacement assay for RNA ligand discovery.

Anal Biochem 2011 Jan 21;408(2):269-76. Epub 2010 Sep 21.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.ab.2010.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980581PMC
January 2011

Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA.

Biochemistry 2009 Sep;48(35):8299-311

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/bi900982tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752669PMC
September 2009

Synthesis and characterization of modified nucleotides in the 970 hairpin loop of Escherichia coli 16S ribosomal RNA.

Bioorg Med Chem 2009 Aug 9;17(16):5887-93. Epub 2009 Jul 9.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2009.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725200PMC
August 2009

A new role for cisplatin: probing ribosomal RNA structure.

Chem Commun (Camb) 2009 Jan 10(1):107-9. Epub 2008 Nov 10.

Department of Chemistry, Wayne State University, Detroit, Michigan, 48202, USA.

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http://dx.doi.org/10.1039/b816633aDOI Listing
January 2009

Identification of a new alpha1,2-fucosyltransferase involved in O-antigen biosynthesis of Escherichia coli O86:B7 and formation of H-type 3 blood group antigen.

Biochemistry 2008 Nov 9;47(44):11590-7. Epub 2008 Oct 9.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/bi801067sDOI Listing
November 2008

Pseudouridines in rRNA helix 69 play a role in loop stacking interactions.

Org Biomol Chem 2008 Nov 19;6(21):3892-5. Epub 2008 Sep 19.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1039/b812731jDOI Listing
November 2008

Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues.

Bioorg Med Chem 2008 Oct 9;16(19):8795-800. Epub 2008 Sep 9.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2008.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583172PMC
October 2008

pH-dependent structural changes of helix 69 from Escherichia coli 23S ribosomal RNA.

RNA 2008 Apr 11;14(4):782-92. Epub 2008 Feb 11.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1261/rna.779908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271367PMC
April 2008

Synthesis and solution conformation studies of 3-substituted uridine and pseudouridine derivatives.

Bioorg Med Chem 2008 Mar 19;16(5):2676-86. Epub 2007 Nov 19.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2007.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2295217PMC
March 2008

Identification and role of functionally important motifs in the 970 loop of Escherichia coli 16S ribosomal RNA.

J Mol Biol 2008 Feb 7;376(3):645-57. Epub 2007 Dec 7.

Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.jmb.2007.11.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262921PMC
February 2008

Characterization of a novel alpha1,2-fucosyltransferase of Escherichia coli O128:b12 and functional investigation of its common motif.

Biochemistry 2008 Jan 14;47(1):378-87. Epub 2007 Dec 14.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/bi701345vDOI Listing
January 2008

Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications.

ACS Chem Biol 2007 Sep;2(9):610-9

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/cb7001494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535799PMC
September 2007

Monitoring aminoglycoside-induced conformational changes in 16S rRNA through acrylamide quenching.

Bioorg Med Chem 2007 Jun 13;15(11):3825-31. Epub 2007 Mar 13.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2007.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001229PMC
June 2007

More pronounced salt dependence and higher reactivity for platination of the hairpin r(CGCGUUGUUCGCG) compared with d(CGCGTTGTTCGCG).

J Biol Inorg Chem 2006 Nov 5;11(8):974-90. Epub 2006 Sep 5.

Biochemistry, Chemical Center, Lund University, 221 00, Lund, Sweden.

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http://dx.doi.org/10.1007/s00775-006-0157-yDOI Listing
November 2006

Probing RNA hairpins with cobalt(III)hexammine and electrospray ionization mass spectrometry.

J Am Soc Mass Spectrom 2006 Oct 9;17(10):1376-1382. Epub 2006 Aug 9.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, 48202, Detroit, MI, USA.

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http://link.springer.com/10.1016/j.jasms.2006.07.006
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http://dx.doi.org/10.1016/j.jasms.2006.07.006DOI Listing
October 2006

Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine.

Bioorg Med Chem 2005 Dec 24;13(24):6777-81. Epub 2005 Aug 24.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096808960500726
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http://dx.doi.org/10.1016/j.bmc.2005.07.061DOI Listing
December 2005

NMR conformational analysis of p-tolyl furanopyrimidine 2'-deoxyribonucleoside and crystal structure of its 3',5'-di-O-acetyl derivative.

Bioorg Med Chem 2005 Feb;13(4):1231-8

Department of Chemistry and Center for Biomedical Research, Oakland University, 2200 N. Squirrel Rd, Rochester, MI 48309-4477, USA.

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http://dx.doi.org/10.1016/j.bmc.2004.11.013DOI Listing
February 2005

Sheep red blood cells armed with anti-CD20 single-chain variable fragments (scFvs) fused to a glycosylphosphatidylinositol (GPI) anchor: a strategy to target CD20-positive tumor cells.

J Immunol Methods 2005 Feb 11;297(1-2):109-24. Epub 2005 Jan 11.

Lymphoma Research Laboratory, Department of Internal Medicine, School of Medicine, Wayne State University Detroit, MI 48201, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002217590400427
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http://dx.doi.org/10.1016/j.jim.2004.12.003DOI Listing
February 2005

Synthesis of 15N-enriched pseudouridine derivatives.

Org Lett 2003 Oct;5(22):4093-6

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/ol035496eDOI Listing
October 2003

Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi.

J Org Chem 2002 Dec;67(25):8847-54

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/jo026364mDOI Listing
December 2002

Photoinduced cleavage by a rhodium complex at G.U mismatches and exposed guanines in large and small RNAs.

Biochimie 2002 Sep;84(9):859-68

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/s0300-9084(02)01403-7DOI Listing
September 2002

Design of novel antibiotics that bind to the ribosomal acyltransfer site.

J Am Chem Soc 2002 Apr;124(13):3229-37

Department of Chemistry, Institute for Drug Design, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1021/ja011695mDOI Listing
April 2002

Aminoglycosides modified by resistance enzymes display diminished binding to the bacterial ribosomal aminoacyl-tRNA site.

Chem Biol 2002 Apr;9(4):455-63

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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April 2002

Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin.

Bioorg Med Chem 2002 Feb;10(2):325-32

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/s0968-0896(01)00283-8DOI Listing
February 2002

A Structural Basis for RNAminus signLigand Interactions.

Chem Rev 1997 Aug;97(5):1489-1514

Department of Chemistry, Wayne State University, Detroit, Michigan 48202.

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August 1997