Christine M Freeman

Christine M Freeman

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Christine M Freeman

Christine M Freeman

Publications by authors named "Christine M Freeman"

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GDF-15 in Pulmonary and Critical Care Medicine.

Am J Respir Cell Mol Biol 2019 06;60(6):621-628

2 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.

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https://www.atsjournals.org/doi/10.1165/rcmb.2018-0379TR
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http://dx.doi.org/10.1165/rcmb.2018-0379TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543753PMC
June 2019

Ablation of the leptin receptor in myeloid cells impairs pulmonary clearance of Streptococcus pneumoniae and alveolar macrophage bactericidal function.

Am J Physiol Lung Cell Mol Physiol 2018 07 22;315(1):L78-L86. Epub 2018 Mar 22.

Department of Integrative and Molecular Physiology, University of Michigan , Ann Arbor, Michigan.

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http://dx.doi.org/10.1152/ajplung.00447.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087898PMC
July 2018

Lung Dendritic Cells: Shaping Immune Responses throughout Chronic Obstructive Pulmonary Disease Progression.

Am J Respir Cell Mol Biol 2017 02;56(2):152-159

4 Pulmonary and Critical Care Medicine Section, Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.

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http://dx.doi.org/10.1165/rcmb.2016-0272TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222925PMC
February 2017

Bacterial Topography of the Healthy Human Lower Respiratory Tract.

mBio 2017 02 14;8(1). Epub 2017 Feb 14.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA

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http://dx.doi.org/10.1128/mBio.02287-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312084PMC
February 2017

MicroRNA-34a Negatively Regulates Efferocytosis by Tissue Macrophages in Part via SIRT1.

J Immunol 2016 Feb 30;196(3):1366-75. Epub 2015 Dec 30.

Graduate Program in Immunology, University of Michigan Health System, Ann Arbor, MI 48109; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109; Pulmonary and Critical Care Medicine Section, VA Ann Arbor Healthcare System, Ann Arbor, MI 48105

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http://dx.doi.org/10.4049/jimmunol.1401838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724467PMC
February 2016

Human CD56+ cytotoxic lung lymphocytes kill autologous lung cells in chronic obstructive pulmonary disease.

PLoS One 2014 31;9(7):e103840. Epub 2014 Jul 31.

Pulmonary & Critical Care Medicine Division, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America; Graduate Program in Immunology, University of Michigan, Ann Arbor, Michigan, United States of America; Pulmonary & Critical Care Medicine Section, Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103840PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117545PMC
November 2015

Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent.

PLoS One 2014 7;9(5):e96421. Epub 2014 May 7.

Pulmonary and Critical Care Medicine Division, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, United States of America; Graduate Program in Immunology, University of Michigan, Ann Arbor, Michigan, United States of America; Pulmonary and Critical Care Medicine Section, Medicine Service, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096421PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013040PMC
October 2015

"B" for Bad, Beneficial, or Both? Lung Lymphoid Neogenesis in Chronic Obstructive Pulmonary Disease.

Am J Respir Crit Care Med 2015 Sep;192(6):648-51

2 Division of Pulmonary and Critical Care Medicine and.

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http://dx.doi.org/10.1164/rccm.201506-1230EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595684PMC
September 2015

Easier said than done: ABO compatibility and D matching in apheresis platelet transfusions.

Transfusion 2015 Aug 11;55(8):1882-8. Epub 2015 Mar 11.

Department of Pathology.

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http://dx.doi.org/10.1111/trf.13077DOI Listing
August 2015

Glucocorticoid-Augmented Efferocytosis Inhibits Pulmonary Pneumococcal Clearance in Mice by Reducing Alveolar Macrophage Bactericidal Function.

J Immunol 2015 Jul 18;195(1):174-84. Epub 2015 May 18.

Graduate Program in Immunology, University of Michigan, Ann Arbor, MI 48109; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109; Medical Service, VA Ann Arbor Healthcare System, Ann Arbor, MI 48105

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http://dx.doi.org/10.4049/jimmunol.1402217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475455PMC
July 2015

Spatial Variation in the Healthy Human Lung Microbiome and the Adapted Island Model of Lung Biogeography.

Ann Am Thorac Soc 2015 Jun;12(6):821-30

1 Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1513/AnnalsATS.201501-029OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590020PMC
June 2015

Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling.

J Exp Med 2015 May 6;212(5):729-42. Epub 2015 Apr 6.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Department of Microbiology and Immunology, University of Michigan Medical School; and Department of Environmental Health Sciences, School of Public Health; University of Michigan, Ann Arbor, MI 48109

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http://dx.doi.org/10.1084/jem.20141675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419346PMC
May 2015

Why do we need a nonhuman primate model of smoking-induced COPD?

Am J Pathol 2015 Mar 7;185(3):610-3. Epub 2015 Jan 7.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan; Medicine and Research Services, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.

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http://dx.doi.org/10.1016/j.ajpath.2014.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348463PMC
March 2015

Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.

PLoS One 2014 15;9(5):e97214. Epub 2014 May 15.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States of America; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097214PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022512PMC
January 2015

Transforming growth factor-β induces microRNA-29b to promote murine alveolar macrophage dysfunction after bone marrow transplantation.

Am J Physiol Lung Cell Mol Physiol 2015 Jan 31;308(1):L86-95. Epub 2014 Oct 31.

Graduate Program in Immunology, University of Michigan Medical School, Ann Arbor, Michigan; Pulmonary and Critical Care Medicine Division, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan;

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http://dx.doi.org/10.1152/ajplung.00283.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281703PMC
January 2015

Role of CC chemokine receptor 4 in natural killer cell activation during acute cigarette smoke exposure.

Am J Pathol 2014 Feb 9;184(2):454-63. Epub 2013 Dec 9.

Department of Pathology and Laboratory Medicine, VA Ann Arbor Healthcare System, Ann Arbor, Michigan; Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906485PMC
February 2014

Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression.

Respir Res 2013 Mar 9;14:33. Epub 2013 Mar 9.

Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, University of Michigan Health Care System, Ann Arbor, MI, 48109-2399, USA.

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http://respiratory-research.com/content/14/1/33
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http://dx.doi.org/10.1186/1465-9921-14-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599854PMC
March 2013

Tyro3 receptor tyrosine kinases in the heterogeneity of apoptotic cell uptake.

Front Biosci (Landmark Ed) 2009 Jan 1;14:2631-46. Epub 2009 Jan 1.

Pulmonary and Critical Care Medicine, Department of Veterans Affairs Healthsystem and University of Michigan Health System, Ann Arbor, MI 48105, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191832PMC
http://dx.doi.org/10.2741/3401DOI Listing
January 2009

The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research.

Proc Am Thorac Soc 2007 Oct;4(7):512-21

Pulmonary and Critical Care Medicine Section, Department of Veterans Affairs Medical Center, 2215 Fuller Road, Ann Arbor, MI 48105-2303, USA.

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http://dx.doi.org/10.1513/pats.200701-002FMDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365762PMC
October 2007

Mononuclear phagocyte-derived interleukin-10 suppresses the innate pulmonary granuloma cytokine response in aged mice.

Am J Pathol 2007 Sep 13;171(3):829-37. Epub 2007 Jul 13.

Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.2353/ajpath.2007.061122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959495PMC
September 2007

CC chemokine receptor 5 and CXC chemokine receptor 6 expression by lung CD8+ cells correlates with chronic obstructive pulmonary disease severity.

Am J Pathol 2007 Sep 19;171(3):767-76. Epub 2007 Jul 19.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, USA.

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http://dx.doi.org/10.2353/ajpath.2007.061177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959492PMC
September 2007

Analysis of inducible costimulatory molecule participation during the induction and elicitation of granulomatous responses to mycobacterial and schistosomal antigens.

Cell Immunol 2005 Sep 21;237(1):45-54. Epub 2005 Nov 21.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1016/j.cellimm.2005.09.005DOI Listing
September 2005