Publications by authors named "Christine M Fillmore"

13Publications

EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors.

Nature 2015 Apr 28;520(7546):239-42. Epub 2015 Jan 28.

1] Stem Cell Program, Boston Children's Hospital, Boston, Massachusetts 02115, USA [2] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Harvard Stem Cell Institute, Cambridge, Massachusetts 02138, USA.

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April 2015

Non-small-cell lung cancers: a heterogeneous set of diseases.

Nat Rev Cancer 2014 Aug;14(8):535-46

1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA. [2] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Belfer Institute for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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August 2014

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Proc Natl Acad Sci U S A 2014 Jul 30;111(28):10299-304. Epub 2014 Jun 30.

Stem Cell Program, Boston Children's Hospital, Boston MA 02115;Harvard Stem Cell Institute, Cambridge, MA 02138;Department of Genetics, Harvard Medical School, Boston, MA 02115;

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July 2014

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.

Cancer Cell 2014 May 1;25(5):590-604. Epub 2014 May 1.

Department of Medicine, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Belfer Institute For Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address:

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May 2014

Lung stem and progenitor cells in tissue homeostasis and disease.

Curr Top Dev Biol 2014 ;107:207-233

Stem Cell Program, Boston Children's Hospital, Boston, Massachusetts, USA.

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September 2014

The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells.

Semin Cancer Biol 2012 Oct 23;22(5-6):462-70. Epub 2012 Apr 23.

Hematology Division, Brigham & Women's Hospital, Boston, MA 02115, USA.

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October 2012

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.

Proc Natl Acad Sci U S A 2010 Dec 22;107(50):21737-42. Epub 2010 Nov 22.

Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA.

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December 2010

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy.

Breast Cancer Res 2008 26;10(2):R25. Epub 2008 Mar 26.

Department of Genetics, Sackler School, Tufts University School of Medicine, Harrison Avenue, Boston, Massachusetts 02111, USA.

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July 2008