Christine Leemann

Long-term experimental evolution of HIV-1 reveals effects of environment and mutational history.

Authors:

Eva Bons Christine Leemann Karin J Metzner Roland R Regoes

PLoS Biol 2020 12 28;18(12):e3001010. Epub 2020 Dec 28.

Department of Environmental Systems Sciences, Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland.

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December 2020

Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon.

Authors:

Benjamin M Wenk Herbert A Mbunkah Ndi N Nsanwe Eyongetah T Mbu Lydia M Besong Bella A Sama Emmanuel Orock Christine Leemann Karin J Metzner

J Antimicrob Chemother 2021 Jan;76(1):124-129

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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January 2021

Parallel evolution of HIV-1 in a long-term experiment.

Authors:

Frederic Bertels Christine Leemann Karin J Metzner Roland Regoes

Mol Biol Evol 2019 Jun 28. Epub 2019 Jun 28.

Department of Environmental Systems Sciences, ETH Zurich, Zurich.

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June 2019

Viral Diversity Based on Next-Generation Sequencing of HIV-1 Provides Precise Estimates of Infection Recency and Time Since Infection.

J Infect Dis 2019 06;220(2):254-265

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich.

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June 2019

Tracing HIV-1 strains that imprint broadly neutralizing antibody responses.

Nature 2018 09 10;561(7723):406-410. Epub 2018 Sep 10.

Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

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September 2018

MinVar: A rapid and versatile tool for HIV-1 drug resistance genotyping by deep sequencing.

Authors:

Michael Huber Karin J Metzner Fabienne D Geissberger Cyril Shah Christine Leemann Thomas Klimkait Jürg Böni Alexandra Trkola Osvaldo Zagordi

J Virol Methods 2017 02 17;240:7-13. Epub 2016 Nov 17.

Institute of Medical Virology, University of Zurich, Zurich, Switzerland. Electronic address:

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February 2017

Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations.

Authors:

Francesca Di Giallonardo Armin Töpfer Melanie Rey Sandhya Prabhakaran Yannick Duport Christine Leemann Stefan Schmutz Nottania K Campbell Beda Joos Maria Rita Lecca Andrea Patrignani Martin Däumer Christian Beisel Peter Rusert Alexandra Trkola Huldrych F Günthard Volker Roth Niko Beerenwinkel Karin J Metzner

Nucleic Acids Res 2014 Aug 27;42(14):e115. Epub 2014 Jun 27.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland

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August 2014

Next-generation sequencing of HIV-1 RNA genomes: determination of error rates and minimizing artificial recombination.

Authors:

Francesca Di Giallonardo Osvaldo Zagordi Yannick Duport Christine Leemann Beda Joos Marzanna Künzli-Gontarczyk Rémy Bruggmann Niko Beerenwinkel Huldrych F Günthard Karin J Metzner

PLoS One 2013 18;8(9):e74249. Epub 2013 Sep 18.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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June 2014

Origin of minority drug-resistant HIV-1 variants in primary HIV-1 infection.

J Infect Dis 2013 Oct 11;208(7):1102-12. Epub 2013 Jul 11.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.

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October 2013

Minority K65R variants and early failure of antiretroviral therapy in HIV-1-infected Eritrean immigrant.

Authors:

Vineeta Bansal Karin J Metzner Barbara Niederost Christine Leemann Jurg Boni Huldrych F Gunthard Jan S Fehr

Emerg Infect Dis 2011 Oct;17(10):1966-8

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October 2011

Characterization of human immunodeficiency virus type 1 (HIV-1) diversity and tropism in 145 patients with primary HIV-1 infection.

Authors:

Philip Rieder Beda Joos Alexandra U Scherrer Herbert Kuster Dominique Braun Christina Grube Barbara Niederöst Christine Leemann Sara Gianella Karin J Metzner Jürg Böni Rainer Weber Huldrych F Günthard

Clin Infect Dis 2011 Dec 12;53(12):1271-9. Epub 2011 Oct 12.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Switzerland.

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December 2011

Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection.

Authors:

Karin J Metzner Christine Leemann Francesca Di Giallonardo Christina Grube Alexandra U Scherrer Dominique Braun Herbert Kuster Rainer Weber Huldrych F Guenthard

PLoS One 2011 6;6(7):e21734. Epub 2011 Jul 6.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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November 2011

HIV-1 transmission after cessation of early antiretroviral therapy among men having sex with men.

Authors:

Philip Rieder Beda Joos Viktor von Wyl Herbert Kuster Christina Grube Christine Leemann Jürg Böni Sabine Yerly Thomas Klimkait Philipp Bürgisser Rainer Weber Marek Fischer Huldrych F Günthard

AIDS 2010 May;24(8):1177-83

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.

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May 2010

Efficient suppression of minority drug-resistant HIV type 1 (HIV-1) variants present at primary HIV-1 infection by ritonavir-boosted protease inhibitor-containing antiretroviral therapy.

Authors:

Karin J Metzner Pia Rauch Viktor von Wyl Christine Leemann Christina Grube Herbert Kuster Jürg Böni Rainer Weber Huldrych F Günthard

J Infect Dis 2010 Apr;201(7):1063-71

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, CH-8091 Zurich, Switzerland.

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April 2010

In vivo efficacy of human immunodeficiency virus neutralizing antibodies: estimates for protective titers.

Authors:

Alexandra Trkola Herbert Kuster Peter Rusert Viktor von Wyl Christine Leemann Rainer Weber Gabriela Stiegler Hermann Katinger Beda Joos Huldrych F Günthard

J Virol 2008 Feb 21;82(3):1591-9. Epub 2007 Nov 21.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Rämistrasse 100, 8091 Zürich, Switzerland.

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February 2008

In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10.

Authors:

Amapola Manrique Peter Rusert Beda Joos Marek Fischer Herbert Kuster Christine Leemann Barbara Niederöst Rainer Weber Gabriela Stiegler Hermann Katinger Huldrych F Günthard Alexandra Trkola

J Virol 2007 Aug 13;81(16):8793-808. Epub 2007 Jun 13.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

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August 2007

Low human immunodeficiency virus envelope diversity correlates with low in vitro replication capacity and predicts spontaneous control of plasma viremia after treatment interruptions.

Authors:

Beda Joos Alexandra Trkola Marek Fischer Herbert Kuster Peter Rusert Christine Leemann Jürg Böni Annette Oxenius David A Price Rodney E Phillips Joseph K Wong Bernard Hirschel Rainer Weber Huldrych F Günthard

J Virol 2005 Jul;79(14):9026-37

University Hospital Zurich, Department of Medicine, Division of Infectious Diseases and Hospital Epidemiology, Rämistrasse 100, CH-8091 Zürich, Switzerland.

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July 2005