Christine H Chung

Christine H Chung

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Christine H Chung

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Evolving role of human papillomavirus as a clinically significant biomarker in head and neck squamous cell carcinoma.

Expert Rev Mol Diagn 2018 Dec 21:1-8. Epub 2018 Dec 21.

b Department of Anatomic Pathology , Moffitt Cancer Center , Tampa , FL , USA.

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http://dx.doi.org/10.1080/14737159.2019.1559056DOI Listing
December 2018

Association of Tumor Size With Histologic and Clinical Outcomes Among Patients With Cytologically Indeterminate Thyroid Nodules.

JAMA Otolaryngol Head Neck Surg 2018 Sep;144(9):788-795

Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1001/jamaoto.2018.1070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233620PMC
September 2018

Impact of oncogene panel results on surgical management of cytologically indeterminate thyroid nodules.

Head Neck 2018 08 6;40(8):1812-1823. Epub 2018 Apr 6.

Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://doi.wiley.com/10.1002/hed.25165
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http://dx.doi.org/10.1002/hed.25165DOI Listing
August 2018

Thyroid Nodules with Indeterminate Cytology: Utility of the American Thyroid Association Sonographic Patterns for Cancer Risk Stratification.

Thyroid 2018 08 17;28(8):1004-1012. Epub 2018 Jul 17.

1 Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center and Research Institute , Tampa, Florida.

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https://www.liebertpub.com/doi/10.1089/thy.2018.0085
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http://dx.doi.org/10.1089/thy.2018.0085DOI Listing
August 2018

PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma.

N Engl J Med 2018 07 4;379(4):341-351. Epub 2018 Jun 4.

From the Departments of Dermatology and Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston (M.R.M.), and South Texas Accelerated Research Therapeutics (START), San Antonio (K.P.P.) - both in Texas; the Department of Medical Oncology, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC (D.R., A.A.T.), the Department of Medical Oncology, Royal North Shore Hospital, St. Leonards, VIC (A.G.), the Department of Medical Oncology, Sir Charles Gairdner Hospital, Perth, WA (A.M.L.), and Royal Brisbane and Women's Hospital and University of Queensland, Brisbane (B.G.M.H.) - all in Australia; the Department of Dermatology, Brigham and Women's Hospital (C.D.S.), the Department of Dermatology, Harvard Medical School (C.D.S.), and the Department of Medical Oncology, Dana-Farber Cancer Institute (G.R.) - all in Boston; Schleswig-Holstein University Hospital, Kiel (A.H.), and University Hospital Essen, Essen and German Cancer Consortium, Essen (D.S.) - both in Germany; University of Colorado Denver, School of Medicine, Aurora (K.D.L.); the Departments of Head and Neck-Endocrine Oncology (C.H.C.) and Cutaneous Oncology (N.I.K.), H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; the Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis (L.H.-A.); the Department of Dermatology, Stanford University School of Medicine, Redwood City (A.L.S.C.), and the Division of Dermatology, City of Hope, Duarte (B.M.) - both in California; the Department of Medicine, Head and Neck Medical Oncology, Memorial Sloan Kettering Cancer Center, New York (L.A.D.), and Regeneron Pharmaceuticals, Tarrytown (F.S., M.M., K.M., G.D.Y., I.L., M.G.F.) - both in New York; Regeneron Pharmaceuticals, Basking Ridge, NJ (B.G., S.L., J.L., J.B., E.S.); University of Arizona Cancer Center, Tucson (H.M.B.), and Banner MD Anderson Cancer (J.H.) and the Department of Medical Oncology, Banner MD Anderson Cancer Center (J.N.), Gilbert - all in Arizona; Medical Oncology Department, Vall D'Hebron University Hospital (I.B.), and Institut Català D'Oncologia, Oncobell Program (IDIBELL), L'Hospitalet de Llobregat (M.G.-M.), Barcelona, and START Madrid-FJD, Hospital Fundación Jiménez Díaz, Madrid (V.M.) - all in Spain; Sarah Cannon Research Institute, Nashville (M.L.J.); and the Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta (T.K.O.).

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http://www.nejm.org/doi/10.1056/NEJMoa1805131
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http://dx.doi.org/10.1056/NEJMoa1805131DOI Listing
July 2018

HEY1 is expressed independent of NOTCH1 and is associated with poor prognosis in head and neck squamous cell carcinoma.

Oral Oncol 2018 Jul 1;82:168-175. Epub 2018 Jun 1.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, 601 N Caroline St., Baltimore, MD 21287, United States; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St., Baltimore, MD 21205, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2018.05.017DOI Listing
July 2018

CancerInSilico: An R/Bioconductor package for combining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer.

PLoS Comput Biol 2018 Jun 19;14(4):e1006935. Epub 2019 Apr 19.

Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006935DOI Listing
June 2018

Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).

J Clin Oncol 2018 May 27;36(14):1412-1418. Epub 2018 Mar 27.

Brigette B.Y. Ma, Edwin P. Hui, Kwok-Wai Lo, Ka-Fai To, K.C. Allen Chan, Y.M. Dennis Lo, Ann D. King, and Anthony T.C. Chan, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region, People's Republic of China; Wan-Teck Lim, National Cancer Centre; Boon-Cher Goh, National University Cancer Institute of Singapore; Alex Y.C. Chang, Johns Hopkins University School of Medicine; Akhil Chopra, OncoCare Cancer Centre, Singapore; Adam Pettinger, Nathan R. Foster, Charles Erlichman, Jun Yin, and Brian A. Costello, Mayo Clinic, Rochester, MN; Jonathan W. Riess, University of California Davis Comprehensive Cancer Center, Sacramento; Barbara J. Gitlitz, University of Southern California Keck School of Medicine, Los Angeles; Dean W. Lim, City of Hope Comprehensive Cancer Center, Duarte, CA; Mark Agulnik, Northwestern University, Evanston, IL; Julie A. Kish and Christine H. Chung, Moffitt Cancer Center, University of South Florida, Tampa, FL; Douglas R. Adkins, Washington University School of Medicine, St Louis, MO; Kevin J. Cullen, University of Maryland, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2017.77.0388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941615PMC
May 2018

Cancer Risk Stratification of Indeterminate Thyroid Nodules: A Cytological Approach.

Thyroid 2017 10 14;27(10):1277-1284. Epub 2017 Sep 14.

1 Department of Head and Neck-Endocrine Oncology, H. Lee Moffitt Cancer Center and Research Institute , Tampa, Florida.

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http://dx.doi.org/10.1089/thy.2017.0221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112164PMC
October 2017

Evaluation of ThyroSeq v2 performance in thyroid nodules with indeterminate cytology.

Endocr Relat Cancer 2017 03 19;24(3):127-136. Epub 2017 Jan 19.

Department of Head and Neck-Endocrine OncologyH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

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http://dx.doi.org/10.1530/ERC-16-0512DOI Listing
March 2017

E1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx- ECOG-ACRIN Cancer Research Group.

J Clin Oncol 2017 Feb 28;35(5):490-497. Epub 2016 Dec 28.

Shanthi Marur and William H. Westra, Johns Hopkins University, Baltimore, MD; Shuli Li, Dana Farber Cancer Institute, Boston, MA; Anthony J. Cmelak, Jill Gilbert, and Barbara A. Murphy, Vanderbilt University, Nashville, TN; Maura L. Gillison and Weiqiang J. Zhao, Ohio State University, Columbus, OH; Robert L. Ferris and Julie E. Bauman, University of Pittsburgh, Pittsburgh, PA; Lynne I. Wagner, Wake Forest School of Medicine, Winston-Salem, NC; David R. Trevarthen, Colorado Cancer Research Program, Denver, CO; Jahagirdar Balkrishna, University of Minnesota, St Paul, MN; Nishant Agrawal, University of Chicago Medicine, Chicago, IL; A. Dimitrios Colevas, Stanford University, Stanford, CA; Christine H. Chung, Moffitt Cancer Center, Tampa, FL; and Barbara Burtness, Yale University, New Haven, CT.

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http://dx.doi.org/10.1200/JCO.2016.68.3300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455313PMC
February 2017

Genomic alterations in human epidermal growth factor receptor 2 (HER2/ERBB2) in head and neck squamous cell carcinoma.

Head Neck 2017 01 21;39(1):E15-E19. Epub 2016 Sep 21.

Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/hed.24587DOI Listing
January 2017

Autologous reconstitution of human cancer and immune system in vivo.

Oncotarget 2017 Jan;8(2):2053-2068

Bloomberg-Kimmel Institute for Cancer Immunotherapy, SKCCC, Johns Hopkins Hospital, Baltimore, MD, USA.

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http://www.oncotarget.com/fulltext/14026
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http://dx.doi.org/10.18632/oncotarget.14026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356779PMC
January 2017

Corrigendum to "Cetuximab activity in dysplastic lesions of the upper aerodigestive tract" [Oral Oncol. 53 (2016) 60-66].

Oral Oncol 2016 Jun 13;57:e8. Epub 2016 Apr 13.

Department of Otolaryngology-Head and Neck Surgery, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA; Milton J Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2016.03.018DOI Listing
June 2016

Application of genomic and proteomic technologies in biomarker discovery.

Am Soc Clin Oncol Educ Book 2012 :377-82

From the Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.14694/EdBook_AM.2012.32.377DOI Listing
April 2016

Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations.

Clin Cancer Res 2016 Apr 20;22(8):2009-19. Epub 2015 Nov 20.

Memorial Sloan Kettering Cancer Center, Human Oncology and Pathogenesis Program, New York, New York. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870591PMC
April 2016

Targeting the PI3K Pathway in Head and Neck Squamous Cell Carcinoma.

Am Soc Clin Oncol Educ Book 2015 :123-8

From the Department of Clinical Oncology, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; Department of Oncology and Department of Head and Neck Surgery-Otolaryngology, The Johns Hopkins Medical Institutions, Baltimore, MD.

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http://dx.doi.org/10.14694/EdBook_AM.2015.35.123DOI Listing
February 2016

Novel Targeted Agents in Head and Neck Squamous Cell Carcinoma.

Hematol Oncol Clin North Am 2015 Dec;29(6):993-1009

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, 1550 Orleans Street CRB-2 Room 546, Baltimore, MD 21287-0014, USA; Department of Otolaryngology-Head and Neck Surgery, Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, 1550 Orleans Street CRB-2 Room 546, Baltimore, MD 21287-0014, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2015.07.006DOI Listing
December 2015

Modernizing Eligibility Criteria for Molecularly Driven Trials.

J Clin Oncol 2015 Sep 20;33(25):2815-20. Epub 2015 Jul 20.

Edward S. Kim, Jennifer L. Ersek, and Earle Burgess, Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC; David Bernstein, Suanna S. Bruinooge, and Richard L. Schilsky, American Society of Clinical Oncology, Alexandria, VA; Susan G. Hilsenbeck, Dan L. Duncan Cancer Center, Baylor College of Medicine; Kelly Hunt, University of Texas MD Anderson Cancer Center, Houston, TX; Christine H. Chung, Johns Hopkins University School of Medicine, Baltimore; Percy Ivy, National Cancer Institute, Bethesda, MD; Adam P. Dicker, Sidney Kimmel Medical College and Cancer Center at Thomas Jefferson University, Philadelphia, PA; Steven Stein, Novartis, East Hanover, NJ; Fadlo R. Khuri, Winship Cancer Institute, Emory University, Atlanta, GA; and Neal Meropol, University Hospitals Case Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1200/JCO.2015.62.1854DOI Listing
September 2015

Diagnostic Accuracy of Follow-Up FDG PET or PET/CT in Patients With Head and Neck Cancer After Definitive Treatment: A Systematic Review and Meta-Analysis.

AJR Am J Roentgenol 2015 Sep;205(3):629-39

1 Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 601 N Caroline St, JHOC 3235, Baltimore, MD 21287.

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http://dx.doi.org/10.2214/AJR.14.14166DOI Listing
September 2015

Implications of the New Face of Head and Neck Cancer.

Oncology (Williston Park) 2015 Sep;29(9):628-30

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September 2015

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas.

Sci Transl Med 2015 Jun;7(293):293ra104

Ludwig Center for Cancer Genetics and Therapeutics, Howard Hughes Medical Institute, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa8507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587492PMC
June 2015

Imaging modality utilization trends in patients with stage III-IV oropharyngeal squamous cell carcinoma.

Am J Nucl Med Mol Imaging 2015 15;5(2):154-61. Epub 2015 Jan 15.

Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University Baltimore, MD ; Department of Otolaryngology and Head and Neck Surgery, Johns Hopkins University Baltimore, MD ; Department of Medical Oncology, Johns Hopkins University Baltimore, MD ; Department of Health Policy and Management, Johns Hopkins University Baltimore, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396006PMC
May 2015

Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features.

Cancer Prev Res (Phila) 2015 Apr 29;8(4):287-95. Epub 2015 Jan 29.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. Milton J. Dance Jr. Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383699PMC
April 2015

Novel targets in head and neck cancer: should we be optimistic?

Clin Cancer Res 2015 Feb 9;21(3):495-7. Epub 2014 Oct 9.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316824PMC
February 2015

Emerging biomarkers in head and neck cancer in the era of genomics.

Nat Rev Clin Oncol 2015 Jan 18;12(1):11-26. Epub 2014 Nov 18.

1] Department of Oncology, Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, 1650 Orleans Street, CRB-1 Room 344, Baltimore, MD 21287-0013, USA. [2] Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Medical Institutions, 1650 Orleans Street, CRB-1 Room 344, Baltimore, MD 21287-0013, USA.

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http://dx.doi.org/10.1038/nrclinonc.2014.192DOI Listing
January 2015

p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma.

J Clin Oncol 2014 Dec 29;32(35):3930-8. Epub 2014 Sep 29.

Christine H. Chung and Elana J. Fertig, Johns Hopkins University, Baltimore, MD; Qiang Zhang and Jonathan Harris, Radiation Therapy Oncology Group Statistical Center, Philadelphia, PA; Christina S. Kong and Quynh-Thu Le, Stanford University, Stanford; Richard C. Jordan, University of California at San Francisco, San Francisco, CA; Paul M. Harari, University of Wisconsin Carbone Cancer Center, Madison; Dian Wang, Medical College of Wisconsin, Milwaukee, WI; Kevin P. Redmond, University of Cincinnati, Cincinnati; Maura L. Gillison, Ohio State University, Columbus, OH; George Shenouda, McGill University Health Centre, Montreal, Quebec, Canada; Andy Trotti, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; and David Raben, University of Colorado, Denver, CO.

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http://dx.doi.org/10.1200/JCO.2013.54.5228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251957PMC
December 2014

Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity.

J Clin Oncol 2014 Dec 3;32(34):3858-66. Epub 2014 Nov 3.

Phuc Felix Nguyen-Tan and Denis Soulieres, Centre Hospitalier de l'Université de Montréal Hôpital Notre-Dame, Montreal; André Fortin, Centre Hospitalier Universitaire Hôtel-Dieu de Québec, Quebec City, Quebec, Canada; Qiang Zhang, NRG Oncology Statistics and Data Management Center; Thomas J. Galloway, Fox Chase Cancer Center, Philadelphia, PA; K. Kian Ang, Randal S. Weber, and David I. Rosenthal, University of Texas MD Anderson Cancer Center, Houston, TX; Harold Kim, Wayne State University, Detroit, MI; Craig Silverman, James Graham Brown Cancer Center, Louisville, KY; Adam Raben, Christiana Care Community Clinical Oncology Program, Newark, DE; Elizabeth Gore, Medical College of Wisconsin, Milwaukee, WI; William H. Westra and Christine H. Chung, Johns Hopkins University, Baltimore, MD; Richard C. Jordan, University of California at San Francisco, San Francisco; Quynh-Thu Le, Stanford University, Stanford, CA; Maura L. Gillison, Ohio State University Comprehensive Cancer Center, Columbus, OH; and Marcy List, University of Chicago Medicine Comprehensive Cancer Research Center, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2014.55.3925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239304PMC
December 2014

Preserving biological heterogeneity with a permuted surrogate variable analysis for genomics batch correction.

Bioinformatics 2014 Oct 6;30(19):2757-63. Epub 2014 Jun 6.

Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21205, USA, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119333, Russia, Research Institute for Genetics and Selection of Industrial Microorganisms "GosNIIGenetika", Moscow 117545, Russia, Department of Statistics and Biostatistics, Rutgers University, NJ 08854, USA and Division of Allergy & Clinical Immunology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173013PMC
October 2014

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.

Oncotarget 2014 Oct;5(19):9281-94

Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253434PMC
http://dx.doi.org/10.18632/oncotarget.2423DOI Listing
October 2014

Prognostic value of FDG PET metabolic tumor volume in human papillomavirus-positive stage III and IV oropharyngeal squamous cell carcinoma.

AJR Am J Roentgenol 2014 Oct;203(4):897-903

1 Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 601 N Caroline St, JHOC 3235, Baltimore, MD 21287.

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http://dx.doi.org/10.2214/AJR.14.12497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332840PMC
October 2014

FDG volumetric parameters and survival outcomes after definitive chemoradiotherapy in patients with recurrent head and neck squamous cell carcinoma.

AJR Am J Roentgenol 2014 Aug;203(2):W139-45

1 Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, 601 N Caroline St / JHOC 3235, Baltimore, MD 21287.

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http://dx.doi.org/10.2214/AJR.13.11654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332824PMC
August 2014

CHK it out! Blocking WEE kinase routs TP53 mutant cancer.

Clin Cancer Res 2014 Aug;20(16):4173-5

Department of Oncology, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860818PMC
August 2014

Epidemiology of oral human papillomavirus infection.

Oral Oncol 2014 May 27;50(5):364-9. Epub 2013 Sep 27.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2013.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968244PMC
May 2014

Using a question prompt list as a communication aid in advanced cancer care.

J Oncol Pract 2014 May 4;10(3):e137-41. Epub 2014 Mar 4.

Johns Hopkins School of Medicine and Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins Medical Institutions, Baltimore, MD

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http://dx.doi.org/10.1200/JOP.2013.001295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888050PMC
May 2014

Loss of HNF6 expression correlates with human pancreatic cancer progression.

Lab Invest 2014 May 17;94(5):517-27. Epub 2014 Mar 17.

1] Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA [2] Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA [3] VA Medical Center, Nashville, TN, USA [4] Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1038/labinvest.2014.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068339PMC
May 2014

Activation of the NOTCH pathway in head and neck cancer.

Cancer Res 2014 Feb 18;74(4):1091-104. Epub 2013 Dec 18.

Authors' Affiliations: Departments of Otolaryngology-Head and Neck Surgery, Oncology and Health Science Informatics, Surgery, Oncology, and Pathology, Johns Hopkins Medical Institutions; Milton J. Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland; and Asuragen Inc., Austin, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944644PMC
February 2014

The twist box domain is required for Twist1-induced prostate cancer metastasis.

Mol Cancer Res 2013 Nov 27;11(11):1387-400. Epub 2013 Aug 27.

Department of Radiation Oncology & Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, 1550 Orleans Street, CRB2 Rm 406, Baltimore, MD 21231.

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http://dx.doi.org/10.1158/1541-7786.MCR-13-0218-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833995PMC
November 2013

Notch signaling mediates melanoma-endothelial cell communication and melanoma cell migration.

Pigment Cell Melanoma Res 2013 Sep 19;26(5):697-707. Epub 2013 Jul 19.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/pcmr.12131DOI Listing
September 2013

Proteomic analysis of oropharyngeal carcinomas reveals novel HPV-associated biological pathways.

Int J Cancer 2013 Feb 20;132(3):568-79. Epub 2012 Jul 20.

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://doi.wiley.com/10.1002/ijc.27699
Publisher Site
http://dx.doi.org/10.1002/ijc.27699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479311PMC
February 2013

Nuclear epidermal growth factor receptor and p16 expression in head and neck squamous cell carcinoma.

Laryngoscope 2012 Dec 19;122(12):2762-8. Epub 2012 Oct 19.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/lary.23647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574977PMC
December 2012

Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy.

Mol Cancer Ther 2012 Nov 27;11(11):2429-39. Epub 2012 Aug 27.

Head and Neck Cancer Research Division, Department of Otolaryngology-Head and Neck Surgery, 1550 Orleans Street, Johns Hopkins University School of Medicine, Cancer Research Building II, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0101-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640459PMC
November 2012

Current role of EGF receptor monoclonal antibodies and tyrosine kinase inhibitors in the management of head and neck squamous cell carcinoma.

Expert Rev Anticancer Ther 2012 Sep;12(9):1149-59

Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231-1000, USA.

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http://dx.doi.org/10.1586/era.12.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715045PMC
September 2012

Impact of HPV-related head and neck cancer in clinical trials: opportunity to translate scientific insight into personalized care.

Otolaryngol Clin North Am 2012 Aug 30;45(4):795-806. Epub 2012 May 30.

Department of Oncology, Johns Hopkins University School of Medicine, 1650 Orleans Street, CRB-1 Room 344, Baltimore, MD 21231-1000, USA.

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http://dx.doi.org/10.1016/j.otc.2012.04.002DOI Listing
August 2012

Biology of human papillomavirus-related oropharyngeal cancer.

Semin Radiat Oncol 2012 Jul;22(3):187-93

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231-1000, USA.

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http://dx.doi.org/10.1016/j.semradonc.2012.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715056PMC
July 2012

New promising molecular targets in head and neck squamous cell carcinoma.

Curr Opin Oncol 2012 May;24(3):235-42

Division of Hematology/Oncology, Department of Internal Medicine, University of New Mexico Cancer Center, Albuquerque, New Mexico, USA.

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http://dx.doi.org/10.1097/CCO.0b013e3283517920DOI Listing
May 2012

Phase 2 trial of oxaliplatin and pemetrexed as an induction regimen in locally advanced head and neck cancer.

Cancer 2012 Feb 15;118(4):1007-13. Epub 2011 Jul 15.

Division of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6307, USA.

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http://doi.wiley.com/10.1002/cncr.26364
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February 2012

Analysis of microsatellite mutations in buccal cells from a case-control study for lung cancer.

Cancer Epidemiol 2012 Feb 6;36(1):e33-9. Epub 2011 Nov 6.

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.canep.2011.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259162PMC
February 2012

Therapeutic targets in head and neck squamous cell carcinoma: identification, evaluation, and clinical translation.

Oral Oncol 2012 Jan 22;48(1):10-7. Epub 2011 Oct 22.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231-1000, United States.

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http://dx.doi.org/10.1016/j.oraloncology.2011.09.013DOI Listing
January 2012

Insulin-like growth factor-1 receptor inhibitor, AMG-479, in cetuximab-refractory head and neck squamous cell carcinoma.

Head Neck 2011 Dec 22;33(12):1804-8. Epub 2010 Jul 22.

Division of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://doi.wiley.com/10.1002/hed.21478
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http://dx.doi.org/10.1002/hed.21478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111896PMC
December 2011

Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.

Mol Cancer Res 2011 Dec 4;9(12):1686-95. Epub 2011 Oct 4.

Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-11-0241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243826PMC
December 2011

Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model.

PLoS One 2011 Feb 2;6(2):e16786. Epub 2011 Feb 2.

Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032792PMC
February 2011

A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-small-cell lung cancer.

J Mol Diagn 2011 Jan 23;13(1):74-84. Epub 2010 Dec 23.

Vanderbilt-Ingram Cancer Center, the Department of Medicine/Division of Hematology-Oncology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2010.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070558PMC
January 2011

Comparative shotgun proteomics using spectral count data and quasi-likelihood modeling.

J Proteome Res 2010 Aug;9(8):4295-305

Department of Biostatistics, Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-8575, USA.

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http://dx.doi.org/10.1021/pr100527gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920032PMC
August 2010

Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.

Cancer Epidemiol Biomarkers Prev 2010 Feb 19;19(2):358-65. Epub 2010 Jan 19.

Division of Hematology/Oncology, Department of Medicine, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232-6307, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-09-0937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846615PMC
February 2010

Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications.

Clin Cancer Res 2009 Nov 27;15(22):6758-62. Epub 2009 Oct 27.

Division of Hematology/Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-6307. USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0784DOI Listing
November 2009

Human papillomavirus in early laryngeal carcinoma.

Laryngoscope 2009 Aug;119(8):1531-7

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6350, USA.

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http://dx.doi.org/10.1002/lary.20509DOI Listing
August 2009