Christine Clarke

Christine Clarke

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Christine Clarke

Christine Clarke

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Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.

Authors:
Manuel A Ferreira Eric R Gamazon Fares Al-Ejeh Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Adalgeir Arason Volker Arndt Kristan J Aronson Banu K Arun Ella Asseryanis Jacopo Azzollini Judith Balmaña Daniel R Barnes Daniel Barrowdale Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Katarzyna Białkowska Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Ake Borg Hiltrud Brauch Hermann Brenner Annegien Broeks Barbara Burwinkel Trinidad Caldés Maria A Caligo Daniele Campa Ian Campbell Federico Canzian Jonathan Carter Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Hans Christiansen Wendy K Chung Kathleen B M Claes Christine L Clarke Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Miguel de la Hoya Joe Dennis Peter Devilee Orland Diez Thilo Dörk Alison M Dunning Miriam Dwek Diana M Eccles Bent Ejlertsen Carolina Ellberg Christoph Engel Mikael Eriksson Peter A Fasching Olivia Fletcher Henrik Flyger Eitan Friedman Debra Frost Marike Gabrielson Manuela Gago-Dominguez Patricia A Ganz Susan M Gapstur Judy Garber Montserrat García-Closas José A García-Sáenz Mia M Gaudet Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Mark H Greene Jacek Gronwald Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Wei He Jane Heyworth Frans B L Hogervorst Antoinette Hollestelle Robert N Hoover John L Hopper Peter J Hulick Keith Humphreys Evgeny N Imyanitov Claudine Isaacs Milena Jakimovska Anna Jakubowska Paul A James Ramunas Janavicius Rachel C Jankowitz Esther M John Nichola Johnson Vijai Joseph Beth Y Karlan Elza Khusnutdinova Johanna I Kiiski Yon-Dschun Ko Michael E Jones Irene Konstantopoulou Vessela N Kristensen Yael Laitman Diether Lambrechts Conxi Lazaro Goska Leslie Jenny Lester Fabienne Lesueur Sara Lindström Jirong Long Jennifer T Loud Jan Lubiński Enes Makalic Arto Mannermaa Mehdi Manoochehri Sara Margolin Tabea Maurer Dimitrios Mavroudis Lesley McGuffog Alfons Meindl Usha Menon Kyriaki Michailidou Austin Miller Marco Montagna Fernando Moreno Lidia Moserle Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Finn C Nielsen Liene Nikitina-Zake Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Håkan Olsson Ana Osorio Janos Papp Tjoung-Won Park-Simon Michael T Parsons Inge Sokilde Pedersen Ana Peixoto Paolo Peterlongo Paul D P Pharoah Dijana Plaseska-Karanfilska Bruce Poppe Nadege Presneau Paolo Radice Johanna Rantala Gad Rennert Harvey A Risch Emmanouil Saloustros Kristin Sanden Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Priyanka Sharma Xiao-Ou Shu Jacques Simard Christian F Singer Penny Soucy Melissa C Southey John J Spinelli Amanda B Spurdle Jennifer Stone Anthony J Swerdlow William J Tapper Jack A Taylor Manuel R Teixeira Mary Beth Terry Alex Teulé Mads Thomassen Kathrin Thöne Darcy L Thull Marc Tischkowitz Amanda E Toland Diana Torres Thérèse Truong Nadine Tung Celine M Vachon Christi J van Asperen Ans M W van den Ouweland Elizabeth J van Rensburg Ana Vega Alessandra Viel Qin Wang Barbara Wappenschmidt Jeffrey N Weitzel Camilla Wendt Robert Winqvist Xiaohong R Yang Drakoulis Yannoukakos Argyrios Ziogas Peter Kraft Antonis C Antoniou Wei Zheng Douglas F Easton Roger L Milne Jonathan Beesley Georgia Chenevix-Trench

Nat Commun 2019 04 15;10(1):1741. Epub 2019 Apr 15.

Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.

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http://dx.doi.org/10.1038/s41467-018-08053-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465407PMC
April 2019

Genome-wide association study of germline variants and breast cancer-specific mortality.

Authors:
Maria Escala-Garcia Qi Guo Thilo Dörk Sander Canisius Renske Keeman Joe Dennis Jonathan Beesley Julie Lecarpentier Manjeet K Bolla Qin Wang Jean Abraham Irene L Andrulis Hoda Anton-Culver Volker Arndt Paul L Auer Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Bram Boeckx Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Hermann Brenner Adam Brentnall Louise Brinton Per Broberg Ian W Brock Sara Y Brucker Barbara Burwinkel Carlos Caldas Trinidad Caldés Daniele Campa Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Jenny Chang-Claude Stephen J Chanock Georgia Chenevix-Trench Ting-Yuan David Cheng Suet-Feung Chin Christine L Clarke Emilie Cordina-Duverger Fergus J Couch David G Cox Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Janet A Dunn Alison M Dunning Lorraine Durcan Miriam Dwek Helena M Earl Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Jonine Figueroa Dieter Flesch-Janys Henrik Flyger Marike Gabrielson Manuela Gago-Dominguez Eva Galle Susan M Gapstur Montserrat García-Closas José A García-Sáenz Mia M Gaudet Angela George Vassilios Georgoulias Graham G Giles Gord Glendon David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Ute Hamann Susan Hankinson Elaine F Harkness Patricia A Harrington Steven N Hart Jaana M Hartikainen Alexander Hein Peter Hillemanns Louise Hiller Bernd Holleczek Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Wolfgang Janni Esther M John Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Cari M Kitahara Julia A Knight Yon-Dschun Ko Linetta B Koppert Veli-Matti Kosma Peter Kraft Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Lian Li Annika Lindblom Sara Lindström Martha Linet Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jan Lubiński Michael P Lux Robert J MacInnis Melanie Maierthaler Tom Maishman Enes Makalic Arto Mannermaa Mehdi Manoochehri Siranoush Manoukian Sara Margolin Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Pooja Middha Nicola Miller Roger L Milne Fernando Moreno Anna Marie Mulligan Claire Mulot Rami Nassir Susan L Neuhausen William T Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Christos Petridis Mila Pinchev Karoliona Prajzendanc Ross Prentice Nadege Presneau Darya Prokofieva Katri Pylkäs Brigitte Rack Paolo Radice Dhanya Ramachandran Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Rebecca Roylance Emmanouil Saloustros Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Lukas Schwentner Rodney J Scott Christopher Scott Caroline Seynaeve Mitul Shah Jacques Simard Ann Smeets Christof Sohn Melissa C Southey Anthony J Swerdlow Aline Talhouk Rulla M Tamimi William J Tapper Manuel R Teixeira Maria Tengström Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Diana Torres Thérèse Truong Constance Turman Clare Turnbull Hans-Ulrich Ulmer Michael Untch Celine Vachon Christi J van Asperen Ans M W van den Ouweland Elke M van Veen Camilla Wendt Alice S Whittemore Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Yan Zhang Douglas F Easton Peter A Fasching Heli Nevanlinna Diana M Eccles Paul D P Pharoah Marjanka K Schmidt

Br J Cancer 2019 Mar 21;120(6):647-657. Epub 2019 Feb 21.

The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Division of Molecular Pathology, Amsterdam, The Netherlands.

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http://www.nature.com/articles/s41416-019-0393-x
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http://dx.doi.org/10.1038/s41416-019-0393-xDOI Listing
March 2019

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

Authors:
Nasim Mavaddat Kyriaki Michailidou Joe Dennis Michael Lush Laura Fachal Andrew Lee Jonathan P Tyrer Ting-Huei Chen Qin Wang Manjeet K Bolla Xin Yang Muriel A Adank Thomas Ahearn Kristiina Aittomäki Jamie Allen Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Paul L Auer Päivi Auvinen Myrto Barrdahl Laura E Beane Freeman Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Hiltrud Brauch Michael Bremer Hermann Brenner Adam Brentnall Ian W Brock Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Daniele Campa Brian D Carter Jose E Castelao Stephen J Chanock Rowan Chlebowski Hans Christiansen Christine L Clarke J Margriet Collée Emilie Cordina-Duverger Sten Cornelissen Fergus J Couch Angela Cox Simon S Cross Kamila Czene Mary B Daly Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Christoph Engel Mikael Eriksson D Gareth Evans Peter A Fasching Jonine Figueroa Olivia Fletcher Henrik Flyger Asta Försti Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Irina R Gilyazova Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Susan E Hankinson Elaine F Harkness Steven N Hart Wei He Alexander Hein Jane Heyworth Peter Hillemanns Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Anthony Howell Guanmengqian Huang Keith Humphreys David J Hunter Milena Jakimovska Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Michael E Jones Arja Jukkola-Vuorinen Audrey Jung Rudolf Kaaks Katarzyna Kaczmarek Vesa Kataja Renske Keeman Michael J Kerin Elza Khusnutdinova Johanna I Kiiski Julia A Knight Yon-Dschun Ko Veli-Matti Kosma Stella Koutros Vessela N Kristensen Ute Krüger Tabea Kühl Diether Lambrechts Loic Le Marchand Eunjung Lee Flavio Lejbkowicz Jenna Lilyquist Annika Lindblom Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jan Lubiński Michael P Lux Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian Sara Margolin John W M Martens Maria Elena Martinez Dimitrios Mavroudis Catriona McLean Alfons Meindl Usha Menon Pooja Middha Nicola Miller Fernando Moreno Anna Marie Mulligan Claire Mulot Victor M Muñoz-Garzon Susan L Neuhausen Heli Nevanlinna Patrick Neven William G Newman Sune F Nielsen Børge G Nordestgaard Aaron Norman Kenneth Offit Janet E Olson Håkan Olsson Nick Orr V Shane Pankratz Tjoung-Won Park-Simon Jose I A Perez Clara Pérez-Barrios Paolo Peterlongo Julian Peto Mila Pinchev Dijana Plaseska-Karanfilska Eric C Polley Ross Prentice Nadege Presneau Darya Prokofyeva Kristen Purrington Katri Pylkäs Brigitte Rack Paolo Radice Rohini Rau-Murthy Gad Rennert Hedy S Rennert Valerie Rhenius Mark Robson Atocha Romero Kathryn J Ruddy Matthias Ruebner Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Daniel F Schmidt Rita K Schmutzler Andreas Schneeweiss Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Caroline Seynaeve Mitul Shah Mark E Sherman Martha J Shrubsole Xiao-Ou Shu Susan Slager Ann Smeets Christof Sohn Penny Soucy Melissa C Southey John J Spinelli Christa Stegmaier Jennifer Stone Anthony J Swerdlow Rulla M Tamimi William J Tapper Jack A Taylor Mary Beth Terry Kathrin Thöne Rob A E M Tollenaar Ian Tomlinson Thérèse Truong Maria Tzardi Hans-Ulrich Ulmer Michael Untch Celine M Vachon Elke M van Veen Joseph Vijai Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Xiaohong R Yang Drakoulis Yannoukakos Yan Zhang Wei Zheng Argyrios Ziogas Alison M Dunning Deborah J Thompson Georgia Chenevix-Trench Jenny Chang-Claude Marjanka K Schmidt Per Hall Roger L Milne Paul D P Pharoah Antonis C Antoniou Nilanjan Chatterjee Peter Kraft Montserrat García-Closas Jacques Simard Douglas F Easton

Am J Hum Genet 2019 Jan 13;104(1):21-34. Epub 2018 Dec 13.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183040
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http://dx.doi.org/10.1016/j.ajhg.2018.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323553PMC
January 2019

Identification of nine new susceptibility loci for endometrial cancer.

Authors:
Tracy A O'Mara Dylan M Glubb Frederic Amant Daniela Annibali Katie Ashton John Attia Paul L Auer Matthias W Beckmann Amanda Black Manjeet K Bolla Hiltrud Brauch Hermann Brenner Louise Brinton Daniel D Buchanan Barbara Burwinkel Jenny Chang-Claude Stephen J Chanock Chu Chen Maxine M Chen Timothy H T Cheng Christine L Clarke Mark Clendenning Linda S Cook Fergus J Couch Angela Cox Marta Crous-Bous Kamila Czene Felix Day Joe Dennis Jeroen Depreeuw Jennifer Anne Doherty Thilo Dörk Sean C Dowdy Matthias Dürst Arif B Ekici Peter A Fasching Brooke L Fridley Christine M Friedenreich Lin Fritschi Jenny Fung Montserrat García-Closas Mia M Gaudet Graham G Giles Ellen L Goode Maggie Gorman Christopher A Haiman Per Hall Susan E Hankison Catherine S Healey Alexander Hein Peter Hillemanns Shirley Hodgson Erling A Hoivik Elizabeth G Holliday John L Hopper David J Hunter Angela Jones Camilla Krakstad Vessela N Kristensen Diether Lambrechts Loic Le Marchand Xiaolin Liang Annika Lindblom Jolanta Lissowska Jirong Long Lingeng Lu Anthony M Magliocco Lynn Martin Mark McEvoy Alfons Meindl Kyriaki Michailidou Roger L Milne Miriam Mints Grant W Montgomery Rami Nassir Håkan Olsson Irene Orlow Geoffrey Otton Claire Palles John R B Perry Julian Peto Loreall Pooler Jennifer Prescott Tony Proietto Timothy R Rebbeck Harvey A Risch Peter A W Rogers Matthias Rübner Ingo Runnebaum Carlotta Sacerdote Gloria E Sarto Fredrick Schumacher Rodney J Scott V Wendy Setiawan Mitul Shah Xin Sheng Xiao-Ou Shu Melissa C Southey Anthony J Swerdlow Emma Tham Jone Trovik Constance Turman Jonathan P Tyrer Celine Vachon David VanDen Berg Adriaan Vanderstichele Zhaoming Wang Penelope M Webb Nicolas Wentzensen Henrica M J Werner Stacey J Winham Alicja Wolk Lucy Xia Yong-Bing Xiang Hannah P Yang Herbert Yu Wei Zheng Paul D P Pharoah Alison M Dunning Peter Kraft Immaculata De Vivo Ian Tomlinson Douglas F Easton Amanda B Spurdle Deborah J Thompson

Nat Commun 2018 08 9;9(1):3166. Epub 2018 Aug 9.

Department of Public Health and Primary Care, University of Cambridge, Centre for Cancer Genetic Epidemiology, Cambridge, CB1 8RN, UK.

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http://dx.doi.org/10.1038/s41467-018-05427-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085317PMC
August 2018

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.

Authors:
Lang Wu Wei Shi Jirong Long Xingyi Guo Kyriaki Michailidou Jonathan Beesley Manjeet K Bolla Xiao-Ou Shu Yingchang Lu Qiuyin Cai Fares Al-Ejeh Esdy Rozali Qin Wang Joe Dennis Bingshan Li Chenjie Zeng Helian Feng Alexander Gusev Richard T Barfield Irene L Andrulis Hoda Anton-Culver Volker Arndt Kristan J Aronson Paul L Auer Myrto Barrdahl Caroline Baynes Matthias W Beckmann Javier Benitez Marina Bermisheva Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Hiltrud Brauch Hermann Brenner Louise Brinton Per Broberg Sara Y Brucker Barbara Burwinkel Trinidad Caldés Federico Canzian Brian D Carter J Esteban Castelao Jenny Chang-Claude Xiaoqing Chen Ting-Yuan David Cheng Hans Christiansen Christine L Clarke Margriet Collée Sten Cornelissen Fergus J Couch David Cox Angela Cox Simon S Cross Julie M Cunningham Kamila Czene Mary B Daly Peter Devilee Kimberly F Doheny Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Miriam Dwek Diana M Eccles Ursula Eilber A Heather Eliassen Christoph Engel Mikael Eriksson Laura Fachal Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Lin Fritschi Marike Gabrielson Manuela Gago-Dominguez Susan M Gapstur Montserrat García-Closas Mia M Gaudet Maya Ghoussaini Graham G Giles Mark S Goldberg David E Goldgar Anna González-Neira Pascal Guénel Eric Hahnen Christopher A Haiman Niclas Håkansson Per Hall Emily Hallberg Ute Hamann Patricia Harrington Alexander Hein Belynda Hicks Peter Hillemanns Antoinette Hollestelle Robert N Hoover John L Hopper Guanmengqian Huang Keith Humphreys David J Hunter Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Kristine Jones Michael E Jones Audrey Jung Rudolf Kaaks Michael J Kerin Elza Khusnutdinova Veli-Matti Kosma Vessela N Kristensen Diether Lambrechts Loic Le Marchand Jingmei Li Sara Lindström Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jan Lubinski Craig Luccarini Michael P Lux Robert J MacInnis Tom Maishman Ivana Maleva Kostovska Arto Mannermaa JoAnn E Manson Sara Margolin Dimitrios Mavroudis Hanne Meijers-Heijboer Alfons Meindl Usha Menon Jeffery Meyer Anna Marie Mulligan Susan L Neuhausen Heli Nevanlinna Patrick Neven Sune F Nielsen Børge G Nordestgaard Olufunmilayo I Olopade Janet E Olson Håkan Olsson Paolo Peterlongo Julian Peto Dijana Plaseska-Karanfilska Ross Prentice Nadege Presneau Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Gad Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Jane Romm Anja Rudolph Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Andreas Schneeweiss Rodney J Scott Christopher G Scott Sheila Seal Mitul Shah Martha J Shrubsole Ann Smeets Melissa C Southey John J Spinelli Jennifer Stone Harald Surowy Anthony J Swerdlow Rulla M Tamimi William Tapper Jack A Taylor Mary Beth Terry Daniel C Tessier Abigail Thomas Kathrin Thöne Rob A E M Tollenaar Diana Torres Thérèse Truong Michael Untch Celine Vachon David Van Den Berg Daniel Vincent Quinten Waisfisz Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter C Willett Robert Winqvist Alicja Wolk Lucy Xia Xiaohong R Yang Argyrios Ziogas Elad Ziv Alison M Dunning Paul D P Pharoah Jacques Simard Roger L Milne Stacey L Edwards Peter Kraft Douglas F Easton Georgia Chenevix-Trench Wei Zheng

Nat Genet 2018 07 18;50(7):968-978. Epub 2018 Jun 18.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1038/s41588-018-0132-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314198PMC
July 2018

Estrogen and progesterone signalling in the normal breast and its implications for cancer development.

Mol Cell Endocrinol 2018 05 26;466:2-14. Epub 2017 Aug 26.

Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney Medical School - Westmead, The University of Sydney, Westmead, NSW 2145, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2017.08.011DOI Listing
May 2018

Profiling differential microRNA expression between in situ, infiltrative and lympho-vascular space invasive breast cancer: a pilot study.

Clin Exp Metastasis 2018 02 6;35(1-2):3-13. Epub 2017 Dec 6.

Translational Oncology, Sydney West Cancer Network, The Crown Princess Mary Cancer Centre Westmead Hospital, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s10585-017-9868-4DOI Listing
February 2018

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Authors:
Roger L Milne Karoline B Kuchenbaecker Kyriaki Michailidou Jonathan Beesley Siddhartha Kar Sara Lindström Shirley Hui Audrey Lemaçon Penny Soucy Joe Dennis Xia Jiang Asha Rostamianfar Hilary Finucane Manjeet K Bolla Lesley McGuffog Qin Wang Cora M Aalfs Marcia Adams Julian Adlard Simona Agata Shahana Ahmed Habibul Ahsan Kristiina Aittomäki Fares Al-Ejeh Jamie Allen Christine B Ambrosone Christopher I Amos Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Norbert Arnold Kristan J Aronson Bernd Auber Paul L Auer Margreet G E M Ausems Jacopo Azzollini François Bacot Judith Balmaña Monica Barile Laure Barjhoux Rosa B Barkardottir Myrto Barrdahl Daniel Barnes Daniel Barrowdale Caroline Baynes Matthias W Beckmann Javier Benitez Marina Bermisheva Leslie Bernstein Yves-Jean Bignon Kathleen R Blazer Marinus J Blok Carl Blomqvist William Blot Kristie Bobolis Bram Boeckx Natalia V Bogdanova Anders Bojesen Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Aniko Bozsik Angela R Bradbury Judith S Brand Hiltrud Brauch Hermann Brenner Brigitte Bressac-de Paillerets Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Joan Brunet Thomas Brüning Barbara Burwinkel Saundra S Buys Jinyoung Byun Qiuyin Cai Trinidad Caldés Maria A Caligo Ian Campbell Federico Canzian Olivier Caron Angel Carracedo Brian D Carter J Esteban Castelao Laurent Castera Virginie Caux-Moncoutier Salina B Chan Jenny Chang-Claude Stephen J Chanock Xiaoqing Chen Ting-Yuan David Cheng Jocelyne Chiquette Hans Christiansen Kathleen B M Claes Christine L Clarke Thomas Conner Don M Conroy Jackie Cook Emilie Cordina-Duverger Sten Cornelissen Isabelle Coupier Angela Cox David G Cox Simon S Cross Katarina Cuk Julie M Cunningham Kamila Czene Mary B Daly Francesca Damiola Hatef Darabi Rosemarie Davidson Kim De Leeneer Peter Devilee Ed Dicks Orland Diez Yuan Chun Ding Nina Ditsch Kimberly F Doheny Susan M Domchek Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Stéphane Dubois Pierre-Antoine Dugué Martine Dumont Alison M Dunning Lorraine Durcan Miriam Dwek Bernd Dworniczak Diana Eccles Ros Eeles Hans Ehrencrona Ursula Eilber Bent Ejlertsen Arif B Ekici A Heather Eliassen Christoph Engel Mikael Eriksson Laura Fachal Laurence Faivre Peter A Fasching Ulrike Faust Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger William D Foulkes Eitan Friedman Lin Fritschi Debra Frost Marike Gabrielson Pragna Gaddam Marilie D Gammon Patricia A Ganz Susan M Gapstur Judy Garber Vanesa Garcia-Barberan José A García-Sáenz Mia M Gaudet Marion Gauthier-Villars Andrea Gehrig Vassilios Georgoulias Anne-Marie Gerdes Graham G Giles Gord Glendon Andrew K Godwin Mark S Goldberg David E Goldgar Anna González-Neira Paul Goodfellow Mark H Greene Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Daphne Gschwantler-Kaulich Pascal Guénel Qi Guo Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Emily Hallberg Ute Hamann Nathalie Hamel Susan Hankinson Thomas V O Hansen Patricia Harrington Steven N Hart Jaana M Hartikainen Catherine S Healey Alexander Hein Sonja Helbig Alex Henderson Jane Heyworth Belynda Hicks Peter Hillemanns Shirley Hodgson Frans B Hogervorst Antoinette Hollestelle Maartje J Hooning Bob Hoover John L Hopper Chunling Hu Guanmengqian Huang Peter J Hulick Keith Humphreys David J Hunter Evgeny N Imyanitov Claudine Isaacs Motoki Iwasaki Louise Izatt Anna Jakubowska Paul James Ramunas Janavicius Wolfgang Janni Uffe Birk Jensen Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Karin Kast Renske Keeman Michael J Kerin Carolien M Kets Machteld Keupers Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Irene Konstantopoulou Veli-Matti Kosma Vessela N Kristensen Torben A Kruse Ava Kwong Anne-Vibeke Lænkholm Yael Laitman Fiona Lalloo Diether Lambrechts Keren Landsman Christine Lasset Conxi Lazaro Loic Le Marchand Julie Lecarpentier Andrew Lee Eunjung Lee Jong Won Lee Min Hyuk Lee Flavio Lejbkowicz Fabienne Lesueur Jingmei Li Jenna Lilyquist Anne Lincoln Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Jennifer T Loud Jan Lubinski Craig Luccarini Michael Lush Robert J MacInnis Tom Maishman Enes Makalic Ivana Maleva Kostovska Kathleen E Malone Siranoush Manoukian JoAnn E Manson Sara Margolin John W M Martens Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis Sylvie Mazoyer Catriona McLean Hanne Meijers-Heijboer Primitiva Menéndez Jeffery Meyer Hui Miao Austin Miller Nicola Miller Gillian Mitchell Marco Montagna Kenneth Muir Anna Marie Mulligan Claire Mulot Sue Nadesan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Ines Nevelsteen Dieter Niederacher Sune F Nielsen Børge G Nordestgaard Aaron Norman Robert L Nussbaum Edith Olah Olufunmilayo I Olopade Janet E Olson Curtis Olswold Kai-Ren Ong Jan C Oosterwijk Nick Orr Ana Osorio V Shane Pankratz Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Rachel Lloyd Inge Søkilde Pedersen Bernard Peissel Ana Peixoto Jose I A Perez Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Mila Pinchev Dijana Plaseska-Karanfilska Bruce Poppe Mary E Porteous Ross Prentice Nadege Presneau Darya Prokofieva Elizabeth Pugh Miquel Angel Pujana Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Hedy S Rennert Valerie Rhenius Kerstin Rhiem Andrea Richardson Gustavo C Rodriguez Atocha Romero Jane Romm Matti A Rookus Anja Rudolph Thomas Ruediger Emmanouil Saloustros Joyce Sanders Dale P Sandler Suleeporn Sangrajrang Elinor J Sawyer Daniel F Schmidt Minouk J Schoemaker Fredrick Schumacher Peter Schürmann Lukas Schwentner Christopher Scott Rodney J Scott Sheila Seal Leigha Senter Caroline Seynaeve Mitul Shah Priyanka Sharma Chen-Yang Shen Xin Sheng Hermela Shimelis Martha J Shrubsole Xiao-Ou Shu Lucy E Side Christian F Singer Christof Sohn 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Xiaohong R Yang Drakoulis Yannoukakos Daniela Zaffaroni Wei Zheng Bin Zhu Argyrios Ziogas Elad Ziv Kristin K Zorn Manuela Gago-Dominguez Arto Mannermaa Håkan Olsson Manuel R Teixeira Jennifer Stone Kenneth Offit Laura Ottini Sue K Park Mads Thomassen Per Hall Alfons Meindl Rita K Schmutzler Arnaud Droit Gary D Bader Paul D P Pharoah Fergus J Couch Douglas F Easton Peter Kraft Georgia Chenevix-Trench Montserrat García-Closas Marjanka K Schmidt Antonis C Antoniou Jacques Simard

Nat Genet 2017 Dec 23;49(12):1767-1778. Epub 2017 Oct 23.

Genomics Center, Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Québec, Canada.

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December 2017

Association analysis identifies 65 new breast cancer risk loci.

Authors:
Kyriaki Michailidou Sara Lindström Joe Dennis Jonathan Beesley Shirley Hui Siddhartha Kar Audrey Lemaçon Penny Soucy Dylan Glubb Asha Rostamianfar Manjeet K Bolla Qin Wang Jonathan Tyrer Ed Dicks Andrew Lee Zhaoming Wang Jamie Allen Renske Keeman Ursula Eilber Juliet D French Xiao Qing Chen Laura Fachal Karen McCue Amy E McCart Reed Maya Ghoussaini Jason S Carroll Xia Jiang Hilary Finucane Marcia Adams Muriel A Adank Habibul Ahsan Kristiina Aittomäki Hoda Anton-Culver Natalia N Antonenkova Volker Arndt Kristan J Aronson Banu Arun Paul L Auer François Bacot Myrto Barrdahl Caroline Baynes Matthias W Beckmann Sabine Behrens Javier Benitez Marina Bermisheva Leslie Bernstein Carl Blomqvist Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Børresen-Dale Judith S Brand Hiltrud Brauch Paul Brennan Hermann Brenner Louise Brinton Per Broberg Ian W Brock Annegien Broeks Angela Brooks-Wilson Sara Y Brucker Thomas Brüning Barbara Burwinkel Katja Butterbach Qiuyin Cai Hui Cai Trinidad Caldés Federico Canzian Angel Carracedo Brian D Carter Jose E Castelao Tsun L Chan Ting-Yuan David Cheng Kee Seng Chia Ji-Yeob Choi Hans Christiansen Christine L Clarke Margriet Collée Don M Conroy Emilie Cordina-Duverger Sten Cornelissen David G Cox Angela Cox Simon S Cross Julie M Cunningham Kamila Czene Mary B Daly Peter Devilee Kimberly F Doheny Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Lorraine Durcan Miriam Dwek Diana M Eccles Arif B Ekici A Heather Eliassen Carolina Ellberg Mingajeva Elvira Christoph Engel Mikael Eriksson Peter A Fasching Jonine Figueroa Dieter Flesch-Janys Olivia Fletcher Henrik Flyger Lin Fritschi Valerie Gaborieau Marike Gabrielson Manuela Gago-Dominguez Yu-Tang Gao Susan M Gapstur José A García-Sáenz Mia M Gaudet Vassilios Georgoulias Graham G Giles Gord Glendon Mark S Goldberg David E Goldgar Anna González-Neira Grethe I Grenaker Alnæs Mervi Grip Jacek Gronwald Anne Grundy Pascal Guénel Lothar Haeberle Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Nathalie Hamel Susan Hankinson Patricia Harrington Steven N Hart Jaana M Hartikainen Mikael Hartman Alexander Hein Jane Heyworth Belynda Hicks Peter Hillemanns Dona N Ho Antoinette Hollestelle Maartje J Hooning Robert N Hoover John L Hopper Ming-Feng Hou Chia-Ni Hsiung Guanmengqian Huang Keith Humphreys Junko Ishiguro Hidemi Ito Motoki Iwasaki Hiroji Iwata Anna Jakubowska Wolfgang Janni Esther M John Nichola Johnson Kristine Jones Michael Jones Arja Jukkola-Vuorinen Rudolf Kaaks Maria Kabisch Katarzyna Kaczmarek Daehee Kang Yoshio Kasuga Michael J Kerin Sofia Khan Elza Khusnutdinova Johanna I Kiiski Sung-Won Kim Julia A Knight Veli-Matti Kosma Vessela N Kristensen Ute Krüger Ava Kwong Diether Lambrechts Loic Le Marchand Eunjung Lee Min Hyuk Lee Jong Won Lee Chuen Neng Lee Flavio Lejbkowicz Jingmei Li Jenna Lilyquist Annika Lindblom Jolanta Lissowska Wing-Yee Lo Sibylle Loibl Jirong Long Artitaya Lophatananon Jan Lubinski Craig Luccarini Michael P Lux Edmond S K Ma Robert J MacInnis Tom Maishman Enes Makalic Kathleen E Malone Ivana Maleva Kostovska Arto Mannermaa Siranoush Manoukian JoAnn E Manson Sara Margolin Shivaani Mariapun Maria Elena Martinez Keitaro Matsuo Dimitrios Mavroudis James McKay Catriona McLean Hanne Meijers-Heijboer Alfons Meindl Primitiva Menéndez Usha Menon Jeffery Meyer Hui Miao Nicola Miller Nur Aishah Mohd Taib Kenneth Muir Anna Marie Mulligan Claire Mulot Susan L Neuhausen Heli Nevanlinna Patrick Neven Sune F Nielsen Dong-Young Noh Børge G Nordestgaard Aaron Norman Olufunmilayo I Olopade Janet E Olson Håkan Olsson Curtis Olswold Nick Orr V Shane Pankratz Sue K Park Tjoung-Won Park-Simon Rachel Lloyd Jose I A Perez Paolo Peterlongo Julian Peto Kelly-Anne Phillips Mila Pinchev Dijana Plaseska-Karanfilska Ross Prentice Nadege Presneau Darya Prokofyeva Elizabeth Pugh Katri Pylkäs Brigitte Rack Paolo Radice Nazneen Rahman Gadi Rennert Hedy S Rennert Valerie Rhenius Atocha Romero Jane Romm Kathryn J Ruddy Thomas Rüdiger Anja 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Wang-Gohrke Clarice R Weinberg Camilla Wendt Alice S Whittemore Hans Wildiers Walter Willett Robert Winqvist Alicja Wolk Anna H Wu Lucy Xia Taiki Yamaji Xiaohong R Yang Cheng Har Yip Keun-Young Yoo Jyh-Cherng Yu Wei Zheng Ying Zheng Bin Zhu Argyrios Ziogas Elad Ziv Sunil R Lakhani Antonis C Antoniou Arnaud Droit Irene L Andrulis Christopher I Amos Fergus J Couch Paul D P Pharoah Jenny Chang-Claude Per Hall David J Hunter Roger L Milne Montserrat García-Closas Marjanka K Schmidt Stephen J Chanock Alison M Dunning Stacey L Edwards Gary D Bader Georgia Chenevix-Trench Jacques Simard Peter Kraft Douglas F Easton

Nature 2017 11 23;551(7678):92-94. Epub 2017 Oct 23.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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November 2017

Emerging functional roles of nuclear receptors in breast cancer.

J Mol Endocrinol 2017 04 13;58(3):R169-R190. Epub 2017 Jan 13.

Westmead Institute for Medical ResearchSydney Medical School - Westmead, University of Sydney, Sydney, New South Wales, Australia.

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April 2017

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.

Authors:
Melissa C Southey David E Goldgar Robert Winqvist Katri Pylkäs Fergus Couch Marc Tischkowitz William D Foulkes Joe Dennis Kyriaki Michailidou Elizabeth J van Rensburg Tuomas Heikkinen Heli Nevanlinna John L Hopper Thilo Dörk Kathleen Bm Claes Jorge Reis-Filho Zhi Ling Teo Paolo Radice Irene Catucci Paolo Peterlongo Helen Tsimiklis Fabrice A Odefrey James G Dowty Marjanka K Schmidt Annegien Broeks Frans B Hogervorst Senno Verhoef Jane Carpenter Christine Clarke Rodney J Scott Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Julian Peto Isabel Dos-Santos-Silva Olivia Fletcher Nichola Johnson Manjeet K Bolla Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Federik Marme Barbara Burwinkel Rongxi Yang Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Stig Bojesen Sune F Nielsen Henrik Flyger Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Hoda Anton-Culver Susan Neuhausen Argyrios Ziogas Christina A Clarke Hermann Brenner Volker Arndt Christa Stegmaier Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Taru A Muranen Kristiina Aittomäki Carl Blomqvist Natalia V Bogdanova Natalia N Antonenkova Annika Lindblom Sara Margolin Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Amanda B Spurdle kConFab Investigators Els Wauters Dominiek Smeets Benoit Beuselinck Giuseppe Floris Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Janet E Olson Celine Vachon Vernon S Pankratz Catriona McLean Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Vessela Kristensen Grethe Grenaker Alnæs Wei Zheng David J Hunter Sara Lindstrom Susan E Hankinson Peter Kraft Irene Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Arja Jukkola-Vuorinen Mervi Grip Saila Kauppila Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Antoinette Hollestelle Montserrat Garcia-Closas Jonine Figueroa Stephen J Chanock Jolanta Lissowska Kamila Czene Hatef Darabi Mikael Eriksson Diana M Eccles Sajjad Rafiq William J Tapper Sue M Gerty Maartje J Hooning John W M Martens J Margriet Collée Madeleine Tilanus-Linthorst Per Hall Jingmei Li Judith S Brand Keith Humphreys Angela Cox Malcolm W R Reed Craig Luccarini Caroline Baynes Alison M Dunning Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Anna Jakubowska Jan Lubinski Katarzyna Jaworska Katarzyna Durda Susan Slager Amanda E Toland Christine B Ambrosone Drakoulis Yannoukakos Anthony Swerdlow Alan Ashworth Nick Orr Michael Jones Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Jacques Simard Martine Dumont Penny Soucy Rosalind Eeles Kenneth Muir Fredrik Wiklund Henrik Gronberg Johanna Schleutker Børge G Nordestgaard Maren Weischer Ruth C Travis David Neal Jenny L Donovan Freddie C Hamdy Kay-Tee Khaw Janet L Stanford William J Blot Stephen Thibodeau Daniel J Schaid Joseph L Kelley Christiane Maier Adam S Kibel Cezary Cybulski Lisa Cannon-Albright Katja Butterbach Jong Park Radka Kaneva Jyotsna Batra Manuel R Teixeira Zsofia Kote-Jarai Ali Amin Al Olama Sara Benlloch Stefan P Renner Arndt Hartmann Alexander Hein Matthias Ruebner Diether Lambrechts Els Van Nieuwenhuysen Ignace Vergote Sandrina Lambretchs Jennifer A Doherty Mary Anne Rossing Stefan Nickels Ursula Eilber Shan Wang-Gohrke Kunle Odunsi Lara E Sucheston-Campbell Grace Friel Galina Lurie Jeffrey L Killeen Lynne R Wilkens Marc T Goodman Ingo Runnebaum Peter A Hillemanns Liisa M Pelttari Ralf Butzow Francesmary Modugno Robert P Edwards Roberta B Ness Kirsten B Moysich Andreas du Bois Florian Heitz Philipp Harter Stefan Kommoss Beth Y Karlan Christine Walsh Jenny Lester Allan Jensen Susanne Krüger Kjaer Estrid Høgdall Bernard Peissel Bernardo Bonanni Loris Bernard Ellen L Goode Brooke L Fridley Robert A Vierkant Julie M Cunningham Melissa C Larson Zachary C Fogarty Kimberly R Kalli Dong Liang Karen H Lu Michelle A T Hildebrandt Xifeng Wu Douglas A Levine Fanny Dao Maria Bisogna Andrew Berchuck Edwin S Iversen Jeffrey R Marks Lucy Akushevich Daniel W Cramer Joellen Schildkraut Kathryn L Terry Elizabeth M Poole Meir Stampfer Shelley S Tworoger Elisa V Bandera Irene Orlow Sara H Olson Line Bjorge Helga B Salvesen Anne M van Altena Katja K H Aben Lambertus A Kiemeney Leon F A G Massuger Tanja Pejovic Yukie Bean Angela Brooks-Wilson Linda E Kelemen Linda S Cook Nhu D Le Bohdan Górski Jacek Gronwald Janusz Menkiszak Claus K Høgdall Lene Lundvall Lotte Nedergaard Svend Aage Engelholm Ed Dicks Jonathan Tyrer Ian Campbell Iain McNeish James Paul Nadeem Siddiqui Rosalind Glasspool Alice S Whittemore Joseph H Rothstein Valerie McGuire Weiva Sieh Hui Cai Xiao-Ou Shu Rachel T Teten Rebecca Sutphen John R McLaughlin Steven A Narod Catherine M Phelan Alvaro N Monteiro David Fenstermacher Hui-Yi Lin Jennifer B Permuth Thomas A Sellers Y Ann Chen Ya-Yu Tsai Zhihua Chen Aleksandra Gentry-Maharaj Simon A Gayther Susan J Ramus Usha Menon Anna H Wu Celeste L Pearce David Van Den Berg Malcolm C Pike Agnieszka Dansonka-Mieszkowska Joanna Plisiecka-Halasa Joanna Moes-Sosnowska Jolanta Kupryjanczyk Paul Dp Pharoah Honglin Song Ingrid Winship Georgia Chenevix-Trench Graham G Giles Sean V Tavtigian Doug F Easton Roger L Milne

J Med Genet 2016 12 5;53(12):800-811. Epub 2016 Sep 5.

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200636PMC
December 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.

Authors:
Chenjie Zeng Xingyi Guo Jirong Long Karoline B Kuchenbaecker Arnaud Droit Kyriaki Michailidou Maya Ghoussaini Siddhartha Kar Adam Freeman John L Hopper Roger L Milne Manjeet K Bolla Qin Wang Joe Dennis Simona Agata Shahana Ahmed Kristiina Aittomäki Irene L Andrulis Hoda Anton-Culver Natalia N Antonenkova Adalgeir Arason Volker Arndt Banu K Arun Brita Arver Francois Bacot Daniel Barrowdale Caroline Baynes Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Carl Blomqvist William J Blot Natalia V Bogdanova Stig E Bojesen Bernardo Bonanni Anne-Lise Borresen-Dale Judith S Brand Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Thomas Brüning Barbara Burwinkel Saundra S Buys Qiuyin Cai Trinidad Caldes Ian Campbell Jane Carpenter Jenny Chang-Claude Ji-Yeob Choi Kathleen B M Claes Christine Clarke Angela Cox Simon S Cross Kamila Czene Mary B Daly Miguel de la Hoya Kim De Leeneer Peter Devilee Orland Diez Susan M Domchek Michele Doody Cecilia M Dorfling Thilo Dörk Isabel Dos-Santos-Silva Martine Dumont Miriam Dwek Bernd Dworniczak Kathleen Egan Ursula Eilber Zakaria Einbeigi Bent Ejlertsen Steve Ellis Debra Frost Fiona Lalloo Peter A Fasching Jonine Figueroa Henrik Flyger Michael Friedlander Eitan Friedman Gaetana Gambino Yu-Tang Gao Judy Garber Montserrat García-Closas Andrea Gehrig Francesca Damiola Fabienne Lesueur Sylvie Mazoyer Dominique Stoppa-Lyonnet Graham G Giles Andrew K Godwin David E Goldgar Anna González-Neira Mark H Greene Pascal Guénel Lothar Haeberle Christopher A Haiman Emily Hallberg Ute Hamann Thomas V O Hansen Steven Hart Jaana M Hartikainen Mikael Hartman Norhashimah Hassan Sue Healey Frans B L Hogervorst Senno Verhoef Carolyn B Hendricks Peter Hillemanns Antoinette Hollestelle Peter J Hulick David J Hunter Evgeny N Imyanitov Claudine Isaacs Hidemi Ito Anna Jakubowska Ramunas Janavicius Katarzyna Jaworska-Bieniek Uffe Birk Jensen Esther M John Charles Joly Beauparlant Michael Jones Maria Kabisch Daehee Kang Beth Y Karlan Saila Kauppila Michael J Kerin Sofia Khan Elza Khusnutdinova Julia A Knight Irene Konstantopoulou Peter Kraft Ava Kwong Yael Laitman Diether Lambrechts Conxi Lazaro Loic Le Marchand Chuen Neng Lee Min Hyuk Lee Jenny Lester Jingmei Li Annelie Liljegren Annika Lindblom Artitaya Lophatananon Jan Lubinski Phuong L Mai Arto Mannermaa Siranoush Manoukian Sara Margolin Frederik Marme Keitaro Matsuo Lesley McGuffog Alfons Meindl Florence Menegaux Marco Montagna Kenneth Muir Anna Marie Mulligan Katherine L Nathanson Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Silje Nord Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Curtis Olswold Ana Osorio Laura Papi Tjoung-Won Park-Simon Ylva Paulsson-Karlsson Stephanie Peeters Bernard Peissel Paolo Peterlongo Julian Peto Georg Pfeiler Catherine M Phelan Nadege Presneau Paolo Radice Nazneen Rahman Susan J Ramus Muhammad Usman Rashid Gad Rennert Kerstin Rhiem Anja Rudolph Ritu Salani Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Rita K Schmutzler Minouk J Schoemaker Peter Schürmann Caroline Seynaeve Chen-Yang Shen Martha J Shrubsole Xiao-Ou Shu Alice Sigurdson Christian F Singer Susan Slager Penny Soucy Melissa Southey Doris Steinemann Anthony Swerdlow Csilla I Szabo Sandrine Tchatchou Manuel R Teixeira Soo H Teo Mary Beth Terry Daniel C Tessier Alex Teulé Mads Thomassen Laima Tihomirova Marc Tischkowitz Amanda E Toland Nadine Tung Clare Turnbull Ans M W van den Ouweland Elizabeth J van Rensburg David Ven den Berg Joseph Vijai Shan Wang-Gohrke Jeffrey N Weitzel Alice S Whittemore Robert Winqvist Tien Y Wong Anna H Wu Drakoulis Yannoukakos Jyh-Cherng Yu Paul D P Pharoah Per Hall Georgia Chenevix-Trench Alison M Dunning Jacques Simard Fergus J Couch Antonis C Antoniou Douglas F Easton Wei Zheng

Breast Cancer Res 2016 06 21;18(1):64. Epub 2016 Jun 21.

Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 2525 West End Avenue, 8th Floor, Nashville, TN, 37203-1738, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962376PMC
June 2016

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis.

EBioMedicine 2016 Apr 18;6:59-72. Epub 2016 Feb 18.

Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD 4072, Australia. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856749PMC
April 2016

Spinal Cord T-Cell Infiltration in the Rat Spared Nerve Injury Model: A Time Course Study.

Int J Mol Sci 2016 Mar 9;17(3):352. Epub 2016 Mar 9.

Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland.

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http://dx.doi.org/10.3390/ijms17030352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813213PMC
March 2016

Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis.

J Cell Sci 2016 Feb 11;129(3):483-91. Epub 2015 Dec 11.

Department of Mechanical Engineering, University of Washington, Seattle, WA 98195, USA Department of Bioengineering, University of Washington, Seattle, WA 98105, USA

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http://dx.doi.org/10.1242/jcs.175976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760302PMC
February 2016

Development of a technique to detect the activated form of the progesterone receptor and correlation with clinical and histopathological characteristics of endometrioid adenocarcinoma of the uterine corpus.

Gynecol Oncol 2015 Sep 2;138(3):663-7. Epub 2015 Jul 2.

University of Arizona Cancer Center-Phoenix, Creighton University School of Medicine at St. Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, AZ 85013, USA.

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September 2015

Minireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?

Mol Endocrinol 2015 Sep 12;29(9):1230-42. Epub 2015 Aug 12.

Westmead Millennium Institute, University of Sydney, Westmead, New South Wales, 2145, Australia.

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http://dx.doi.org/10.1210/me.2015-1152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414684PMC
September 2015

Osteoblast differentiation profiles define sex specific gene expression patterns in craniosynostosis.

Bone 2015 Jul 7;76:169-76. Epub 2015 Mar 7.

Seattle Children's Research Institute, Center for Developmental Biology and Regenerative Medicine, Seattle, WA, USA; Seattle Children's Craniofacial Center, Seattle, WA, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546839PMC
July 2015

Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial.

Breast Cancer Res Treat 2015 Jun 28;151(2):309-18. Epub 2015 Apr 28.

Centre for Cancer Research, Westmead Millennium Institute, University of Sydney Medical School, Hawkesbury Road, Westmead, NSW, 2145, Australia.

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June 2015

Impact of progesterone on stem/progenitor cells in the human breast.

J Mammary Gland Biol Neoplasia 2015 Jun 8;20(1-2):27-37. Epub 2015 Aug 8.

Centre for Cancer Research, Westmead Millennium Institute, University of Sydney Medical School, Westmead, NSW, Australia.

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http://dx.doi.org/10.1007/s10911-015-9339-yDOI Listing
June 2015

Preface.

J Mammary Gland Biol Neoplasia 2015 Jun;20(1-2):5-7

Pathology, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.

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June 2015

Prediction of breast cancer risk based on profiling with common genetic variants.

Authors:
Nasim Mavaddat Paul D P Pharoah Kyriaki Michailidou Jonathan Tyrer Mark N Brook Manjeet K Bolla Qin Wang Joe Dennis Alison M Dunning Mitul Shah Robert Luben Judith Brown Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Kamila Czene Hatef Darabi Mikael Eriksson Julian Peto Isabel Dos-Santos-Silva Frank Dudbridge Nichola Johnson Marjanka K Schmidt Annegien Broeks Senno Verhoef Emiel J Rutgers Anthony Swerdlow Alan Ashworth Nick Orr Minouk J Schoemaker Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Fergus J Couch Janet E Olson Celine Vachon Vernon S Pankratz Diether Lambrechts Hans Wildiers Chantal Van Ongeval Erik van Limbergen Vessela Kristensen Grethe Grenaker Alnæs Silje Nord Anne-Lise Borresen-Dale Heli Nevanlinna Taru A Muranen Kristiina Aittomäki Carl Blomqvist Jenny Chang-Claude Anja Rudolph Petra Seibold Dieter Flesch-Janys Peter A Fasching Lothar Haeberle Arif B Ekici Matthias W Beckmann Barbara Burwinkel Frederik Marme Andreas Schneeweiss Christof Sohn Amy Trentham-Dietz Polly Newcomb Linda Titus Kathleen M Egan David J Hunter Sara Lindstrom Rulla M Tamimi Peter Kraft Nazneen Rahman Clare Turnbull Anthony Renwick Sheila Seal Jingmei Li Jianjun Liu Keith Humphreys Javier Benitez M Pilar Zamora Jose Ignacio Arias Perez Primitiva Menéndez Anna Jakubowska Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Natalia V Bogdanova Natalia N Antonenkova Thilo Dörk Hoda Anton-Culver Susan L Neuhausen Argyrios Ziogas Leslie Bernstein Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J van Asperen Angela Cox Simon S Cross Malcolm W R Reed Elza Khusnutdinova Marina Bermisheva Darya Prokofyeva Zalina Takhirova Alfons Meindl Rita K Schmutzler Christian Sutter Rongxi Yang Peter Schürmann Michael Bremer Hans Christiansen Tjoung-Won Park-Simon Peter Hillemanns Pascal Guénel Thérèse Truong Florence Menegaux Marie Sanchez Paolo Radice Paolo Peterlongo Siranoush Manoukian Valeria Pensotti John L Hopper Helen Tsimiklis Carmel Apicella Melissa C Southey Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Alice J Sigurdson Michele M Doody Ute Hamann Diana Torres Hans-Ulrich Ulmer Asta Försti Elinor J Sawyer Ian Tomlinson Michael J Kerin Nicola Miller Irene L Andrulis Julia A Knight Gord Glendon Anna Marie Mulligan Georgia Chenevix-Trench Rosemary Balleine Graham G Giles Roger L Milne Catriona McLean Annika Lindblom Sara Margolin Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Ursula Eilber Shan Wang-Gohrke Maartje J Hooning Antoinette Hollestelle Ans M W van den Ouweland Linetta B Koppert Jane Carpenter Christine Clarke Rodney Scott Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Hermann Brenner Volker Arndt Christa Stegmaier Aida Karina Dieffenbach Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Kenneth Offit Joseph Vijai Mark Robson Rohini Rau-Murthy Miriam Dwek Ruth Swann Katherine Annie Perkins Mark S Goldberg France Labrèche Martine Dumont Diana M Eccles William J Tapper Sajjad Rafiq Esther M John Alice S Whittemore Susan Slager Drakoulis Yannoukakos Amanda E Toland Song Yao Wei Zheng Sandra L Halverson Anna González-Neira Guillermo Pita M Rosario Alonso Nuria Álvarez Daniel Herrero Daniel C Tessier Daniel Vincent Francois Bacot Craig Luccarini Caroline Baynes Shahana Ahmed Mel Maranian Catherine S Healey Jacques Simard Per Hall Douglas F Easton Montserrat Garcia-Closas

J Natl Cancer Inst 2015 May 8;107(5). Epub 2015 Apr 8.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (NM, PDPP, KM, MKB, QW, JD, RL, JBr, DFE); Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK (PDPP, JT, AMD, MS, CL, CB, SA, MM, CSH, DFE); Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK (MNB, ASw, MJS); Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark (SEB, BGN, SFN); Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN, SFN); Faculty of Health and Medical Sciences, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (SEB, BGN); Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Herlev, Denmark (HF); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (KC, HD, ME, KH, PHa); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK (JP, IdSS, FD); Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK (NJ, AA, NO, MGC); Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands (MKS, AB, SV, EJR); Division of Breast Cancer Research, Institute of Cancer Research, London, UK (ASw); Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (JF, SJC, LB, ASi, MD); Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland (JLis); Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (FJC); Department of Health Sciences Research, Mayo Clinic, Rochester, MN (JEO, CV, VSP, SS); Vesalius Research Center, VIB, Leuven, Belgium (DL); Laboratory for Translational Genetics, Department of Oncology, University of

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May 2015

Prevalence of BRCA1 and BRCA2 germline mutations in patients with triple-negative breast cancer.

Breast Cancer Res Treat 2015 Feb 15;150(1):71-80. Epub 2015 Feb 15.

School of Biomedical Sciences & Pharmacy, Centre for Information-Based Medicine, Hunter Medical Research Institute, University of Newcastle, Lot 1 Kookaburra Circuit, New Lambton Heights, Newcastle, NSW, 2305, Australia.

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February 2015

Binding sites analyser (BiSA): software for genomic binding sites archiving and overlap analysis.

PLoS One 2014 12;9(2):e87301. Epub 2014 Feb 12.

Westmead Institute for Cancer Research, Sydney Medical School, University of Sydney and the Westmead Millennium Institute, Westmead, New South Wales, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922719PMC
January 2015

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia.

Authors:
Amanda B Spurdle Fergus J Couch Michael T Parsons Lesley McGuffog Daniel Barrowdale Manjeet K Bolla Qin Wang Sue Healey Rita Schmutzler Barbara Wappenschmidt Kerstin Rhiem Eric Hahnen Christoph Engel Alfons Meindl Nina Ditsch Norbert Arnold Hansjoerg Plendl Dieter Niederacher Christian Sutter Shan Wang-Gohrke Doris Steinemann Sabine Preisler-Adams Karin Kast Raymonda Varon-Mateeva Steve Ellis Debra Frost Radka Platte Jo Perkins D Gareth Evans Louise Izatt Ros Eeles Julian Adlard Rosemarie Davidson Trevor Cole Giulietta Scuvera Siranoush Manoukian Bernardo Bonanni Frederique Mariette Stefano Fortuzzi Alessandra Viel Barbara Pasini Laura Papi Liliana Varesco Rosemary Balleine Katherine L Nathanson Susan M Domchek Kenneth Offitt Anna Jakubowska Noralane Lindor Mads Thomassen Uffe Birk Jensen Johanna Rantala Åke Borg Irene L Andrulis Alexander Miron Thomas V O Hansen Trinidad Caldes Susan L Neuhausen Amanda E Toland Heli Nevanlinna Marco Montagna Judy Garber Andrew K Godwin Ana Osorio Rachel E Factor Mary B Terry Timothy R Rebbeck Beth Y Karlan Melissa Southey Muhammad Usman Rashid Nadine Tung Paul D P Pharoah Fiona M Blows Alison M Dunning Elena Provenzano Per Hall Kamila Czene Marjanka K Schmidt Annegien Broeks Sten Cornelissen Senno Verhoef Peter A Fasching Matthias W Beckmann Arif B Ekici Dennis J Slamon Stig E Bojesen Børge G Nordestgaard Sune F Nielsen Henrik Flyger Jenny Chang-Claude Dieter Flesch-Janys Anja Rudolph Petra Seibold Kristiina Aittomäki Taru A Muranen Päivi Heikkilä Carl Blomqvist Jonine Figueroa Stephen J Chanock Louise Brinton Jolanta Lissowska Janet E Olson Vernon S Pankratz Esther M John Alice S Whittemore Dee W West Ute Hamann Diana Torres Hans Ulrich Ulmer Thomas Rüdiger Peter Devilee Robert A E M Tollenaar Caroline Seynaeve Christi J Van Asperen Diana M Eccles William J Tapper Lorraine Durcan Louise Jones Julian Peto Isabel dos-Santos-Silva Olivia Fletcher Nichola Johnson Miriam Dwek Ruth Swann Anita L Bane Gord Glendon Anna M Mulligan Graham G Giles Roger L Milne Laura Baglietto Catriona McLean Jane Carpenter Christine Clarke Rodney Scott Hiltrud Brauch Thomas Brüning Yon-Dschun Ko Angela Cox Simon S Cross Malcolm W R Reed Jan Lubinski Katarzyna Jaworska-Bieniek Katarzyna Durda Jacek Gronwald Thilo Dörk Natalia Bogdanova Tjoung-Won Park-Simon Peter Hillemanns Christopher A Haiman Brian E Henderson Fredrick Schumacher Loic Le Marchand Barbara Burwinkel Frederik Marme Harald Surovy Rongxi Yang Hoda Anton-Culver Argyrios Ziogas Maartje J Hooning J Margriet Collée John W M Martens Madeleine M A Tilanus-Linthorst Hermann Brenner Aida Karina Dieffenbach Volke Arndt Christa Stegmaier Robert Winqvist Katri Pylkäs Arja Jukkola-Vuorinen Mervi Grip Annika Lindblom Sara Margolin Vijai Joseph Mark Robson Rohini Rau-Murthy Anna González-Neira José Ignacio Arias Pilar Zamora Javier Benítez Arto Mannermaa Vesa Kataja Veli-Matti Kosma Jaana M Hartikainen Paolo Peterlongo Daniela Zaffaroni Monica Barile Fabio Capra Paolo Radice Soo H Teo Douglas F Easton Antonis C Antoniou Georgia Chenevix-Trench David E Goldgar

Breast Cancer Res 2014 Dec 23;16(6):3419. Epub 2014 Dec 23.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352262PMC
December 2014

Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver.

Clin Cancer Res 2014 Dec 14;20(24):6618-30. Epub 2014 Oct 14.

Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia. Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia. University of Sydney, Westmead Hospital, Sydney, New South Wales, Australia. Westmead Institute for Cancer Research, Westmead Millennium Institute, Westmead Hospital, Sydney, New South Wales, Australia.

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December 2014

Biobanking sustainability--experiences of the Australian Breast Cancer Tissue Bank (ABCTB).

Biopreserv Biobank 2014 Dec;12(6):395-401

1 Australian Breast Cancer Tissue Bank, University of Sydney , Westmead Millennium Institute, Westmead, Australia .

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December 2014

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.

Authors:
Kristen S Purrington Seth Slettedahl Manjeet K Bolla Kyriaki Michailidou Kamila Czene Heli Nevanlinna Stig E Bojesen Irene L Andrulis Angela Cox Per Hall Jane Carpenter Drakoulis Yannoukakos Christopher A Haiman Peter A Fasching Arto Mannermaa Robert Winqvist Hermann Brenner Annika Lindblom Georgia Chenevix-Trench Javier Benitez Anthony Swerdlow Vessela Kristensen Pascal Guénel Alfons Meindl Hatef Darabi Mikael Eriksson Rainer Fagerholm Kristiina Aittomäki Carl Blomqvist Børge G Nordestgaard Sune F Nielsen Henrik Flyger Xianshu Wang Curtis Olswold Janet E Olson Anna Marie Mulligan Julia A Knight Sandrine Tchatchou Malcolm W R Reed Simon S Cross Jianjun Liu Jingmei Li Keith Humphreys Christine Clarke Rodney Scott Florentia Fostira George Fountzilas Irene Konstantopoulou Brian E Henderson Fredrick Schumacher Loic Le Marchand Arif B Ekici Arndt Hartmann Matthias W Beckmann Jaana M Hartikainen Veli-Matti Kosma Vesa Kataja Arja Jukkola-Vuorinen Katri Pylkäs Saila Kauppila Aida Karina Dieffenbach Christa Stegmaier Volker Arndt Sara Margolin Rosemary Balleine Jose Ignacio Arias Perez M Pilar Zamora Primitiva Menéndez Alan Ashworth Michael Jones Nick Orr Patrick Arveux Pierre Kerbrat Thérèse Truong Peter Bugert Amanda E Toland Christine B Ambrosone France Labrèche Mark S Goldberg Martine Dumont Argyrios Ziogas Eunjung Lee Gillian S Dite Carmel Apicella Melissa C Southey Jirong Long Martha Shrubsole Sandra Deming-Halverson Filomena Ficarazzi Monica Barile Paolo Peterlongo Katarzyna Durda Katarzyna Jaworska-Bieniek Robert A E M Tollenaar Caroline Seynaeve Thomas Brüning Yon-Dschun Ko Carolien H M Van Deurzen John W M Martens Mieke Kriege Jonine D Figueroa Stephen J Chanock Jolanta Lissowska Ian Tomlinson Michael J Kerin Nicola Miller Andreas Schneeweiss William J Tapper Susan M Gerty Lorraine Durcan Catriona Mclean Roger L Milne Laura Baglietto Isabel dos Santos Silva Olivia Fletcher Nichola Johnson Laura J Van'T Veer Sten Cornelissen Asta Försti Diana Torres Thomas Rüdiger Anja Rudolph Dieter Flesch-Janys Stefan Nickels Caroline Weltens Giuseppe Floris Matthieu Moisse Joe Dennis Qin Wang Alison M Dunning Mitul Shah Judith Brown Jacques Simard Hoda Anton-Culver Susan L Neuhausen John L Hopper Natalia Bogdanova Thilo Dörk Wei Zheng Paolo Radice Anna Jakubowska Jan Lubinski Peter Devillee Hiltrud Brauch Maartje Hooning Montserrat García-Closas Elinor Sawyer Barbara Burwinkel Frederick Marmee Diana M Eccles Graham G Giles Julian Peto Marjanka Schmidt Annegien Broeks Ute Hamann Jenny Chang-Claude Diether Lambrechts Paul D P Pharoah Douglas Easton V Shane Pankratz Susan Slager Celine M Vachon Fergus J Couch

Hum Mol Genet 2014 Nov 13;23(22):6034-46. Epub 2014 Jun 13.

Department of Health Sciences Research, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204763PMC
November 2014

Bioinformatic analysis of cis-regulatory interactions between progesterone and estrogen receptors in breast cancer.

PeerJ 2014 18;2:e654. Epub 2014 Nov 18.

Centre for Cancer Research, Westmead Millennium Institute, Sydney Medical School-Westmead, University of Sydney , Australia.

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November 2014

Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis.

Am J Hum Genet 2014 Aug;95(2):235-40

Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98101, USA; Department of Pediatrics, University of Washington, Seattle, WA 98195, USA; Craniofacial Center, Seattle Children's Hospital, Seattle, WA 98105, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129399PMC
August 2014

Breast cancer prognosis predicted by nuclear receptor-coregulator networks.

Mol Oncol 2014 Jul 4;8(5):998-1013. Epub 2014 Apr 4.

Westmead Millennium Institute, Sydney Medical School - Westmead, University of Sydney, NSW, Australia. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528526PMC
July 2014

PRMT2 and RORγ expression are associated with breast cancer survival outcomes.

Mol Endocrinol 2014 Jul 9;28(7):1166-85. Epub 2014 Jun 9.

Institute for Molecular Bioscience (T.G.O., P.B., J.G., N.E., S.G., D.H.D., G.E.O.M.) and School of Biomedical Science (A.G.S.), The University of Queensland, Brisbane, Queensland 4072, Australia; Institute of Health and Biomedical Innovation (E.D.), Queensland University of Technology, Translational Research Institute, Brisbane, Queensland 4102, Australia; Prince Henry's Institute of Medical Research (J.W.F., P.J.F., E.R.S.), Clayton, Victoria 3168, Australia; Dame Roma Mitchell Cancer Research Laboratory (W.D.T.), School of Medicine, The University of Adelaide, Adelaide 5005, South Australia, Australia; Western Australian Institute for Medical Research (P.J.L.), University of Western Australia, Perth, Western Australia 6009, Australia; Westmead Millennium Institute (C.L.C.), Sydney Medical School, Westmead, University of Sydney, New South Wales 2006, Australia; and Department of Molecular and Clinical Medicine/Wallenberg Laboratory (G.E.O.M.), University of Gothenburg, S-405 30 Gothenburg, Sweden.

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http://dx.doi.org/10.1210/me.2013-1403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414829PMC
July 2014

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.

Authors:
Kristen S Purrington Susan Slager Diana Eccles Drakoulis Yannoukakos Peter A Fasching Penelope Miron Jane Carpenter Jenny Chang-Claude Nicholas G Martin Grant W Montgomery Vessela Kristensen Hoda Anton-Culver Paul Goodfellow William J Tapper Sajjad Rafiq Susan M Gerty Lorraine Durcan Irene Konstantopoulou Florentia Fostira Athanassios Vratimos Paraskevi Apostolou Irene Konstanta Vassiliki Kotoula Sotiris Lakis Meletios A Dimopoulos Dimosthenis Skarlos Dimitrios Pectasides George Fountzilas Matthias W Beckmann Alexander Hein Matthias Ruebner Arif B Ekici Arndt Hartmann Ruediger Schulz-Wendtland Stefan P Renner Wolfgang Janni Brigitte Rack Christoph Scholz Julia Neugebauer Ulrich Andergassen Michael P Lux Lothar Haeberle Christine Clarke Nirmala Pathmanathan Anja Rudolph Dieter Flesch-Janys Stefan Nickels Janet E Olson James N Ingle Curtis Olswold Seth Slettedahl Jeanette E Eckel-Passow S Keith Anderson Daniel W Visscher Victoria L Cafourek Hugues Sicotte Naresh Prodduturi Elisabete Weiderpass Leslie Bernstein Argyrios Ziogas Jennifer Ivanovich Graham G Giles Laura Baglietto Melissa Southey Veli-Matti Kosma Hans-Peter Fischer Malcom W R Reed Simon S Cross Sandra Deming-Halverson Martha Shrubsole Qiuyin Cai Xiao-Ou Shu Mary Daly Joellen Weaver Eric Ross Jennifer Klemp Priyanka Sharma Diana Torres Thomas Rüdiger Heidrun Wölfing Hans-Ulrich Ulmer Asta Försti Thaer Khoury Shicha Kumar Robert Pilarski Charles L Shapiro Dario Greco Päivi Heikkilä Kristiina Aittomäki Carl Blomqvist Astrid Irwanto Jianjun Liu Vernon Shane Pankratz Xianshu Wang Gianluca Severi Arto Mannermaa Douglas Easton Per Hall Hiltrud Brauch Angela Cox Wei Zheng Andrew K Godwin Ute Hamann Christine Ambrosone Amanda Ewart Toland Heli Nevanlinna Celine M Vachon Fergus J Couch

Carcinogenesis 2014 May 9;35(5):1012-9. Epub 2013 Dec 9.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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May 2014

The government is investing in doctors rather than nurses.

Authors:
Christine Clarke

Nurs Stand 2014 May;28(37):34

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May 2014

Prohibitin expression is associated with high grade breast cancer but is not a driver of amplification at 17q21.33.

Pathology 2013 12;45(7):629-36

*Sydney Medical School - Westmead, University of Sydney, Westmead †Westmead Institute for Cancer Research, Westmead ‡Westmead Millennium Institute, Westmead §Tissue Pathology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead ||Translational Oncology, Sydney West Cancer Network, Western Sydney and Nepean Blue Mountains Local Health Districts, Westmead ¶Anatomical Pathology, St Vincent's Hospital, Darlinghurst **Prince of Wales Clinical School, University of New South Wales, Randwick ††School of Medical Sciences University of New South Wales, Randwick ‡‡School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia §§Genetics Branch, National Cancer Institute, Bethesda MD USA ||||these authors contributed equally to this work.

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December 2013

Changed lineage composition is an early event in breast carcinogenesis.

Histol Histopathol 2013 09 15;28(9):1197-204. Epub 2013 Apr 15.

Westmead Institute for Cancer Research, Sydney Medical School - Westmead, University of Sydney at Westmead Millennium Institute, Westmead, New South Wales, Australia.

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September 2013

[Glial cells and chronic pain: from the laboratory to clinical hope].

Rev Med Suisse 2013 Jun;9(392):1342-5

Centre d'antalgie, Service d'anesthésiologie, CHUV, 1011 Lausanne.

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June 2013

Open source tools for management and archiving of digital microscopy data to allow integration with patient pathology and treatment information.

Diagn Pathol 2013 Feb 12;8:22. Epub 2013 Feb 12.

Australian Breast Cancer Tissue Bank, University of Sydney at the Westmead Millennium Institute, Darcy Road, Westmead, NSW 2145, Australia.

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http://dx.doi.org/10.1186/1746-1596-8-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575263PMC
February 2013

Non-overlapping progesterone receptor cistromes contribute to cell-specific transcriptional outcomes.

PLoS One 2012 24;7(4):e35859. Epub 2012 Apr 24.

Westmead Institute for Cancer Research, Sydney Medical School-Westmead, University of Sydney at the Westmead Millennium Institute, Westmead Hospital, Westmead, New South Wales, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335806PMC
August 2012

Protein arginine methyltransferase 6-dependent gene expression and splicing: association with breast cancer outcomes.

Endocr Relat Cancer 2012 Aug 22;19(4):509-26. Epub 2012 Jul 22.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.

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August 2012

Preview: MCE special issue on molecular mechanisms of action in progesterone signalling.

Mol Cell Endocrinol 2012 Jun 8;357(1-2):1-3. Epub 2012 Feb 8.

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June 2012

Development of a data entry auditing protocol and quality assurance for a tissue bank database.

Cell Tissue Bank 2012 Mar 18;13(1):9-13. Epub 2011 Feb 18.

Breast Cancer Tissue Bank, The University of Sydney at the Westmead Millennium Institute, Darcy Road, Westmead, NSW 2145, Australia.

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March 2012

Electronic biorepository application system: web-based software to manage receipt, peer review, and approval of researcher applications to a biobank.

Biopreserv Biobank 2012 Feb 17;10(1):37-44. Epub 2012 Jan 17.

1 Breast Cancer Tissue Bank, Westmead Millennium Institute, Sydney Medical School-Westmead, University of Sydney , Westmead, Australia .

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http://dx.doi.org/10.1089/bio.2011.0038DOI Listing
February 2012

Common breast cancer susceptibility loci are associated with triple-negative breast cancer.

Cancer Res 2011 Oct 15;71(19):6240-9. Epub 2011 Aug 15.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327299PMC
October 2011

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.

Authors:
Christopher A Haiman Gary K Chen Celine M Vachon Federico Canzian Alison Dunning Robert C Millikan Xianshu Wang Foluso Ademuyiwa Shahana Ahmed Christine B Ambrosone Laura Baglietto Rosemary Balleine Elisa V Bandera Matthias W Beckmann Christine D Berg Leslie Bernstein Carl Blomqvist William J Blot Hiltrud Brauch Julie E Buring Lisa A Carey Jane E Carpenter Jenny Chang-Claude Stephen J Chanock Daniel I Chasman Christine L Clarke Angela Cox Simon S Cross Sandra L Deming Robert B Diasio Athanasios M Dimopoulos W Ryan Driver Thomas Dünnebier Lorraine Durcan Diana Eccles Christopher K Edlund Arif B Ekici Peter A Fasching Heather S Feigelson Dieter Flesch-Janys Florentia Fostira Asta Försti George Fountzilas Susan M Gerty Graham G Giles Andrew K Godwin Paul Goodfellow Nikki Graham Dario Greco Ute Hamann Susan E Hankinson Arndt Hartmann Rebecca Hein Judith Heinz Andrea Holbrook Robert N Hoover Jennifer J Hu David J Hunter Sue A Ingles Astrid Irwanto Jennifer Ivanovich Esther M John Nicola Johnson Arja Jukkola-Vuorinen Rudolf Kaaks Yon-Dschun Ko Laurence N Kolonel Irene Konstantopoulou Veli-Matti Kosma Swati Kulkarni Diether Lambrechts Adam M Lee Loïc Le Marchand Timothy Lesnick Jianjun Liu Sara Lindstrom Arto Mannermaa Sara Margolin Nicholas G Martin Penelope Miron Grant W Montgomery Heli Nevanlinna Stephan Nickels Sarah Nyante Curtis Olswold Julie Palmer Harsh Pathak Dimitrios Pectasides Charles M Perou Julian Peto Paul D P Pharoah Loreall C Pooler Michael F Press Katri Pylkäs Timothy R Rebbeck Jorge L Rodriguez-Gil Lynn Rosenberg Eric Ross Thomas Rüdiger Isabel dos Santos Silva Elinor Sawyer Marjanka K Schmidt Rüdiger Schulz-Wendtland Fredrick Schumacher Gianluca Severi Xin Sheng Lisa B Signorello Hans-Peter Sinn Kristen N Stevens Melissa C Southey William J Tapper Ian Tomlinson Frans B L Hogervorst Els Wauters JoEllen Weaver Hans Wildiers Robert Winqvist David Van Den Berg Peggy Wan Lucy Y Xia Drakoulis Yannoukakos Wei Zheng Regina G Ziegler Afshan Siddiq Susan L Slager Daniel O Stram Douglas Easton Peter Kraft Brian E Henderson Fergus J Couch

Nat Genet 2011 Oct 30;43(12):1210-4. Epub 2011 Oct 30.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, USA.

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http://dx.doi.org/10.1038/ng.985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279120PMC
October 2011

Progesterone induces adult mammary stem cell expansion.

Nature 2010 Jun;465(7299):803-7

Ontario Cancer Institute, Department of Medical Biophysics and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto M5G 2M9, Ontario, Canada.

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June 2010

A class discovery and class prediction approach to histopathological classification of mammographic screen detected columnar cell lesions of the breast.

Pathology 2010 Jan;42(1):28-36

Department of Tissue Pathology, Institute of Clinical Pathology and Medical Research, Sydney West Area Health Service, New South Wales, Australia.

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http://dx.doi.org/10.3109/00313020903434355DOI Listing
January 2010

Hormone-responsive model of primary human breast epithelium.

J Mammary Gland Biol Neoplasia 2009 Dec 21;14(4):367-79. Epub 2009 Nov 21.

Westmead Institute for Cancer Research, Westmead Millennium Institute, Westmead, New South Wales, 2145, Australia.

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http://dx.doi.org/10.1007/s10911-009-9160-6DOI Listing
December 2009

Progesterone action in human tissues: regulation by progesterone receptor (PR) isoform expression, nuclear positioning and coregulator expression.

Nucl Recept Signal 2009 Dec 31;7:e009. Epub 2009 Dec 31.

Westmead Institute for Cancer Research, Westmead Millennium Institute, University of Sydney Western Clinical School, Westmead, NSW, Australia.

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http://dx.doi.org/10.1621/nrs.07009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807635PMC
December 2009

Nuclear matrix binding is critical for progesterone receptor movement into nuclear foci.

FASEB J 2009 Feb 17;23(2):546-56. Epub 2008 Oct 17.

Westmead Institute for Cancer Research, University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.

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http://www.fasebj.org/doi/10.1096/fj.08-113639
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http://dx.doi.org/10.1096/fj.08-113639DOI Listing
February 2009

Antiproliferative actions of the synthetic androgen, mibolerone, in breast cancer cells are mediated by both androgen and progesterone receptors.

J Steroid Biochem Mol Biol 2008 Jun 20;110(3-5):236-43. Epub 2008 Apr 20.

Dame Roma Mitchell Cancer Research Laboratories, Discipline of Medicine, University of Adelaide and Hanson Institute, Adelaide, South Australia 5000, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S096007600800103
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http://dx.doi.org/10.1016/j.jsbmb.2007.10.014DOI Listing
June 2008

Visceral neuropathy and intestinal pseudo-obstruction in a murine model of a nuclear inclusion disease.

Gastroenterology 2007 Dec 21;133(6):1971-8. Epub 2007 Aug 21.

Department of Laboratories, Children's Hospital and Regional Medical Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1053/j.gastro.2007.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696337PMC
December 2007

Focal subnuclear distribution of progesterone receptor is ligand dependent and associated with transcriptional activity.

Mol Endocrinol 2007 Jan 4;21(1):14-29. Epub 2006 Oct 4.

Westmead Institute for Cancer Research, Westmead Hospital, Westmead, New South Wales 2145, Australia.

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http://dx.doi.org/10.1210/me.2006-0041DOI Listing
January 2007

Overlapping and distinct expression of progesterone receptors A and B in mouse uterus and mammary gland during the estrous cycle.

Endocrinology 2006 Dec 15;147(12):5503-12. Epub 2006 Sep 15.

Westmead Institute for Cancer Research, University of Sydney at the Westmead Millennium Institute, and Department of Gynecological Oncology, Westmead Hospital, New South Wales 2145, Australia.

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http://dx.doi.org/10.1210/en.2006-0040DOI Listing
December 2006

Predictors of vinorelbine pharmacokinetics and pharmacodynamics in patients with cancer.

J Clin Oncol 2006 Jun 1;24(16):2448-55. Epub 2006 May 1.

Westmead Institute for Cancer Research Westmead Millennium Institute, Department of Translational Oncology, Westmead, Australia.

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http://dx.doi.org/10.1200/JCO.2005.02.1295DOI Listing
June 2006

Altered progesterone receptor isoform expression remodels progestin responsiveness of breast cancer cells.

Mol Endocrinol 2005 Nov 23;19(11):2713-35. Epub 2005 Jun 23.

Westmead Institute for Cancer Research, University of Sydney Westmead Hospital, Westmead Millennium Institute, Darcy Road, Westmead, New South Wales 2145, Australia.

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http://dx.doi.org/10.1210/me.2005-0126DOI Listing
November 2005

Evaluation of Hox11L1 in the fmc/fmc rat model of chronic intestinal pseudo-obstruction.

J Pediatr Surg 2005 Nov;40(11):1760-5

Department of Pediatrics, Children's Hospital and Regional Medical Center and University of Washington, Seattle, WA 98105, USA.

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http://dx.doi.org/10.1016/j.jpedsurg.2005.07.010DOI Listing
November 2005

Hox11L1 expression by precursors of enteric smooth muscle: an alternative explanation for megacecum in HOX11L1-/- mice.

Pediatr Dev Pathol 2005 Mar-Apr;8(2):148-61. Epub 2005 Apr 7.

Department of Pathology, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98105, USA.

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http://dx.doi.org/10.1007/s10024-005-1126-0DOI Listing
July 2005

Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer.

Clin Pharmacol Ther 2005 Jan;77(1):33-42

Westmead Institute for Cancer Research, Department of Nuclear Medicine, Westmead Hospital, University of Sydney, Camperdown, Australia.

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http://dx.doi.org/10.1016/j.clpt.2004.09.002DOI Listing
January 2005

Malignant autosomal recessive osteopetrosis caused by spontaneous mutation of murine Rank.

J Bone Miner Res 2004 Oct 21;19(10):1689-97. Epub 2004 Jul 21.

Department of Pathology, Children's Hospital and Regional Medical Center, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1359/JBMR.040713DOI Listing
October 2004

Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle.

Endocrinology 2004 Jul 24;145(7):3487-94. Epub 2004 Mar 24.

Department of Gynecological Oncology, Westmead Hospital, Westmead, New South Wales 2145, Australia.

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http://dx.doi.org/10.1210/en.2004-0212DOI Listing
July 2004

CYP3A5 genotype and midazolam clearance in Australian patients receiving chemotherapy.

Clin Pharmacol Ther 2004 Jun;75(6):529-38

Westmead Institute for Cancer Research, and Department of Translational Oncology, Westmead and Nepean Hospitals, Westmead, New South Wales,

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http://dx.doi.org/10.1016/j.clpt.2004.02.005DOI Listing
June 2004

Expression of progesterone receptor A and B isoforms in low-grade endometrial stromal sarcoma.

Int J Gynecol Pathol 2004 Apr;23(2):138-44

Translational Oncology Westmead and Nepean Hospitals, Westmead, Australia.

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April 2004

Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A.

Genes Chromosomes Cancer 2004 Mar;39(3):236-48

Westmead Institute for Cancer Research, University of Sydney at Westmead Millennium Institute, Westmead Hospital, Westmead, Australia.

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http://dx.doi.org/10.1002/gcc.10321DOI Listing
March 2004

Subnuclear distribution of progesterone receptors A and B in normal and malignant endometrium.

J Clin Endocrinol Metab 2004 Mar;89(3):1429-42

Westmead Institute for Cancer Research, University of Sydney at the Westmead Millennium Institute, NSW, Australia.

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http://dx.doi.org/10.1210/jc.2003-031111DOI Listing
March 2004

Reversibility of liver failure secondary to metastatic breast cancer by vinorelbine and cisplatin chemotherapy.

Cancer Chemother Pharmacol 2003 Nov 18;52(5):367-70. Epub 2003 Jul 18.

Department of Oncology, Leicester Royal Infirmary, University Hospitals of Leicester, Leicester, LE1 5WW, UK.

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http://dx.doi.org/10.1007/s00280-003-0679-8DOI Listing
November 2003

Genetic background modifies intestinal pseudo-obstruction and the expression of a reporter gene in Hox11L1-/- mice.

Gastroenterology 2003 Nov;125(5):1428-40

Department of Pediatrics, University of Washington School of Medicine, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NW, Seattle, WA 98105, USA.

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http://dx.doi.org/10.1016/j.gastro.2003.08.021DOI Listing
November 2003

Expression and transcriptional activity of progesterone receptor A and progesterone receptor B in mammalian cells.

Breast Cancer Res 2002 2;4(5):187-90. Epub 2002 Jul 2.

Westmead Institute for Cancer Research, University of Sydney Westmead Hospital, New South Wales, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC138742PMC
March 2003

Cell proliferation in the normal mouse mammary gland and inhibition by phenylbutyrate.

Mol Cancer Ther 2002 Oct;1(12):1025-33

Department of Gynaecological Oncology, Westmead Institute for Cancer Research, Westmead Hospital, Westmead, New South Wales 2145, Australia.

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October 2002