Christine Chow

Christine Chow

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Christine Chow

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Amino acid-linked platinum(II) compounds: non-canonical nucleoside preferences and influence on glycosidic bond stabilities.

J Biol Inorg Chem 2019 Jul 29. Epub 2019 Jul 29.

Department of Chemistry, Wayne State University, Detroit, MI, 48202, USA.

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http://dx.doi.org/10.1007/s00775-019-01693-yDOI Listing
July 2019

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases.

Mod Pathol 2019 Jun 25. Epub 2019 Jun 25.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1038/s41379-019-0302-0DOI Listing
June 2019

Use of Immunohistochemical Markers (HNF-1β, Napsin A, ER, CTH, and ASS1) to Distinguish Endometrial Clear Cell Carcinoma From Its Morphologic Mimics Including Arias-Stella Reaction.

Int J Gynecol Pathol 2019 May 13. Epub 2019 May 13.

Department of Pathology and Laboratory Medicine, University of British Columbia (J.X.J., B.T.-C, B.G., D.G.H., L.N.H.) Department of Molecular Oncology, British Columbia Cancer Research Centre (D.R.C.) Genetic Pathology Evaluation Centre (S.L., A.S.C., C.C.) Department of Pathology, Vancouver General Hospital (B.G., L.N.H.), Vancouver, British Columbia, Canada.

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http://Insights.ovid.com/crossref?an=00004347-900000000-9910
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http://dx.doi.org/10.1097/PGP.0000000000000609DOI Listing
May 2019

The use of electrospray ionization mass spectrometry to monitor RNA-ligand interactions.

Methods Enzymol 2019 27;623:315-337. Epub 2019 May 27.

Wayne State University, Detroit, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2019.05.013DOI Listing
May 2019

Chemical probing for examining the structure of modified RNAs and ligand binding to RNA.

Methods 2019 03 2;156:110-120. Epub 2018 Nov 2.

Department of Chemistry, 5101 Cass Ave., Wayne State University, Detroit, MI 48202, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10462023183020
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http://dx.doi.org/10.1016/j.ymeth.2018.10.015DOI Listing
March 2019

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.

Authors:
Peter F Rambau Robert A Vierkant Maria P Intermaggio Linda E Kelemen Marc T Goodman Esther Herpel Paul D Pharoah Stefan Kommoss Mercedes Jimenez-Linan Beth Y Karlan Aleksandra Gentry-Maharaj Usha Menon Susanna Hernando Polo Francisco J Candido Dos Reis Jennifer Anne Doherty Simon A Gayther Raghwa Sharma Melissa C Larson Paul R Harnett Emma Hatfield Jurandyr M de Andrade Gregg S Nelson Helen Steed Joellen M Schildkraut Micheal E Carney Estrid Høgdall Alice S Whittemore Martin Widschwendter Catherine J Kennedy Frances Wang Qin Wang Chen Wang Sebastian M Armasu Frances Daley Penny Coulson Micheal E Jones Micheal S Anglesio Christine Chow Anna de Fazio Montserrat García-Closas Sara Y Brucker Cezary Cybulski Holly R Harris Andreas D Hartkopf Tomasz Huzarski Allan Jensen Jan Lubiński Oleg Oszurek Javier Benitez Fady Mina Annette Staebler Florin Andrei Taran Jana Pasternak Aline Talhouk Mary Anne Rossing Joy Hendley Robert P Edwards Sian Fereday Francesmary Modugno Roberta B Ness Weiva Sieh Mona A El-Bahrawy Stacey J Winham Jenny Lester Susanne K Kjaer Jacek Gronwald Peter Sinn Peter A Fasching Jenny Chang-Claude Kirsten B Moysich David D Bowtell Brenda Y Hernandez Hugh Luk Sabine Behrens Mitul Shah Audrey Jung Prafull Ghatage Jennifer Alsop Kathryn Alsop Jesús García-Donas Pamela J Thompson Anthony J Swerdlow Chloe Karpinskyj Alicia Cazorla-Jiménez María J García Susha Deen Lynne R Wilkens José Palacios Andrew Berchuck Jennifer M Koziak James D Brenton Linda S Cook Ellen L Goode David G Huntsman Susan J Ramus Martin Köbel

J Pathol Clin Res 2018 10 21;4(4):250-261. Epub 2018 Sep 21.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1002/cjp2.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174617PMC
October 2018

Tubo-Ovarian Transitional Cell Carcinoma and High-grade Serous Carcinoma Show Subtly Different Immunohistochemistry Profiles.

Int J Gynecol Pathol 2018 Jul 27. Epub 2018 Jul 27.

British Columbia Cancer Agency (J.M., A.N.K., A.T., D.C., D.G.H.) Department of Pathology, University of British Columbia (A.N.K., B.T.-C., C.C., A.C., C.B.G., D.G.H.), Vancouver, British Columbia, Canada Memorial Sloan Kettering Cancer Center, New York, New York (R.S.) Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands (S.H.) Department of Women's Health, Tübingen University Hospital, Tübingen (S.K.) Department of Gynecologic Oncology, Kliniken Essen Mitte, Essen (A.D.B.) Gynecologic Oncology Center, Kiel (J.P.) Institute of Pathology, Friedrichshafen (F.K.), Germany.

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http://dx.doi.org/10.1097/PGP.0000000000000538DOI Listing
July 2018

Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling.

Biochemistry 2018 02 5;57(5):772-780. Epub 2018 Jan 5.

Department of Chemistry, Wayne State University , 5101 Cass Avenue, Detroit, Michigan 48202, United States.

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http://pubs.acs.org/doi/10.1021/acs.biochem.7b01083
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http://dx.doi.org/10.1021/acs.biochem.7b01083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856478PMC
February 2018

Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes.

Org Biomol Chem 2017 Oct;15(40):8535-8543

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1039/c7ob02147jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663508PMC
October 2017

The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes.

Bioorg Med Chem 2016 09 25;24(18):4486-4491. Epub 2016 Jul 25.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992606PMC
September 2016

Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions.

Acc Chem Res 2016 05 11;49(5):893-901. Epub 2016 Apr 11.

Department of Chemistry, Wayne State University , Detroit, Michigan 48202, United States.

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http://dx.doi.org/10.1021/acs.accounts.6b00014DOI Listing
May 2016

Molecular subtype profiling of invasive breast cancers weakly positive for estrogen receptor.

Breast Cancer Res Treat 2016 Feb 4;155(3):483-90. Epub 2016 Feb 4.

Department of Laboratory Medicine and Pathology, University of British Columbia, 899 W 12th Ave, Vancouver, BC, V5Z 1M9, Canada.

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http://dx.doi.org/10.1007/s10549-016-3689-zDOI Listing
February 2016

Modulation of conformational changes in helix 69 mutants by pseudouridine modifications.

Biophys Chem 2015 May-Jun;200-201:48-55. Epub 2015 Mar 11.

Department of Chemistry, Wayne State University, Detroit, MI 48202, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bpc.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414897PMC
January 2016

Chlamydia testing: Reaching high-risk sexually active young people in the community.

Int J STD AIDS 2016 Jan 29;27(1):78-9. Epub 2015 Apr 29.

Infection and Immunity Research Institute, St George's, University of London, London, UK Department of Genitourinary & HIV Medicine, St George's Healthcare NHS Trust, London, UK

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http://dx.doi.org/10.1177/0956462415581729DOI Listing
January 2016

Morphologic and Molecular Characteristics of Mixed Epithelial Ovarian Cancers.

Am J Surg Pathol 2015 Nov;39(11):1548-57

*Department of Molecular Oncology §Cancer Control Research, BC Cancer Agency Cancer Research Centre †Department of Pathology and Laboratory Medicine ‡Genetic Pathology Evaluation Centre, Anatomical Pathology at the Vancouver General Hospital ‡‡Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, BC, Canada ∥Department of Internal Medicine, University of New Mexico, Albuquerque, NM §§Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB ¶The Leeds Teaching Hospitals NHS Trust, Leeds #Barts Health NHS Trust, London, United Kingdom **Institut für Pathologie, Referenzzentrum für Gynäkopathologie, Mannheim ††Gynecologic Oncology Center, Kiel ∥∥Department of Gynecology and Obstetrics, Tuebingen University Women's Hospital, Tuebingen, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604016PMC
November 2015

Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins.

Int J Mol Sci 2015 Sep 7;16(9):21392-409. Epub 2015 Sep 7.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.3390/ijms160921392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613259PMC
September 2015

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations.

Nucleic Acids Res 2014 Apr 26;42(6):3971-81. Epub 2013 Dec 26.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1093/nar/gkt1329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973299PMC
April 2014

Amino acid-linked platinum(II) analogues have altered specificity for RNA compared to cisplatin.

Chem Commun (Camb) 2014 Apr 13;50(30):3918-20. Epub 2014 Jan 13.

Department of Chemistry, Wayne State University, 5101 Cass Ave., Detroit, MI 48202, USA.

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http://dx.doi.org/10.1039/c3cc49035aDOI Listing
April 2014

Immunohistochemical characterization of prototypical endometrial clear cell carcinoma--diagnostic utility of HNF-1β and oestrogen receptor.

Histopathology 2014 Mar 7;64(4):585-96. Epub 2013 Dec 7.

Department of Pathology and Laboratory Medicine, Genetic Pathology Evaluation Centre, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/his.12286DOI Listing
March 2014

A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard.

Mod Pathol 2013 Nov 24;26(11):1438-50. Epub 2013 May 24.

1] Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada [2] Genetic Pathology Evaluation Centre, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/modpathol.2013.97DOI Listing
November 2013

Accelerating type-specific ovarian carcinoma research: Calculator for Ovarian Subtype Prediction (COSP) is a reliable high-throughput tool for case review.

Histopathology 2013 Nov 2;63(5):704-12. Epub 2013 Sep 2.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Gynecology and Obstetrics, Tuebingen University, Tuebingen, Germany.

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http://dx.doi.org/10.1111/his.12219DOI Listing
November 2013

Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium.

Cancer Epidemiol Biomarkers Prev 2013 Oct 23;22(10):1677-86. Epub 2013 Jul 23.

Authors' Affiliations: Department of Pathology and Laboratory Medicine; Department of Population Health Research, Alberta Health Services-Cancer Care and Department of Medical Genetics, University of Calgary, Calgary, Alberta; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medical Oncology; Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology; Division of Biomedical Statistics and Informatics, Department of Health Science Research; Division of Experimental Pathology and Laboratory Medicine, Department of Laboratory Medicine and Pathology; Division of Epidemiology, Department of Health Science Research, Mayo Clinic, Rochester, Minnesota; Biostatistics and Informatics Shared Resource, University of Kansas Medical Center, Kansas City, Kansas; University of Texas School of Public Health, Houston, Texas; Roswell Park Cancer Institute, Buffalo, New York, New York; Women's Cancer Research Center, Magee-Womens Research Institute, University of Pittsburgh Cancer Institute; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania; Gynaecological Cancer Research Centre, Women's Cancer, UCL EGA Institute for Women's Health; Department of Pathology, Cancer Institute, UCL, London, United Kingdom; and Department of Preventive Medicine, Keck School of Medicine, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955399PMC
October 2013

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study.

Lancet Oncol 2013 Aug 9;14(9):853-62. Epub 2013 Jul 9.

Division of Epidemiology, Department of Health Research and Policy, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1016/S1470-2045(13)70253-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006367PMC
August 2013

Probing the stabilizing effects of modified nucleotides in the bacterial decoding region of 16S ribosomal RNA.

Bioorg Med Chem 2013 May 21;21(10):2720-6. Epub 2013 Mar 21.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2013.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683315PMC
May 2013

Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA.

Bioorg Med Chem 2013 Mar 10;21(5):1240-7. Epub 2013 Jan 10.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2012.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594512PMC
March 2013

Ligand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence.

Angew Chem Int Ed Engl 2012 Nov 24;51(48):12095-8. Epub 2012 Oct 24.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1002/anie.201206000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741684PMC
November 2012

Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly.

ACS Chem Biol 2012 May 24;7(5):871-8. Epub 2012 Feb 24.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1021/cb200497qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356499PMC
May 2012

Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and human.

Biopolymers 2012 Feb 19;97(2):94-106. Epub 2011 Aug 19.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1002/bip.21706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269404PMC
February 2012

Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas.

J Pathol 2011 Jul 18;224(3):328-33. Epub 2011 May 18.

The Center for Translational and Applied Genomics (CTAG) at the British Columbia (BC) Cancer Agency, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.2911DOI Listing
July 2011

Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNA(Lys).

Chem Biol 2011 Jul;18(7):928-36

Institute of Applied Physics and Center for Functional Nanostructures, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.

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http://dx.doi.org/10.1016/j.chembiol.2011.03.016DOI Listing
July 2011

Probing conformational states of modified helix 69 in 50S ribosomes.

J Am Chem Soc 2011 Jun 16;133(22):8396-9. Epub 2011 May 16.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/ja2005658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106124PMC
June 2011

Calculator for ovarian carcinoma subtype prediction.

Mod Pathol 2011 Apr 3;24(4):512-21. Epub 2010 Dec 3.

Genetic Pathology Evaluation Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1038/modpathol.2010.215DOI Listing
April 2011

Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas.

J Pathol 2011 Apr 7;223(5):567-73. Epub 2011 Mar 7.

Department of Pathology and Laboratory Medicine, University of British Columbia, British Columbia Cancer Agency, 3427-600 West 10th Avenue, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.2848DOI Listing
April 2011

A modified fluorescent intercalator displacement assay for RNA ligand discovery.

Anal Biochem 2011 Jan 21;408(2):269-76. Epub 2010 Sep 21.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.ab.2010.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2980581PMC
January 2011

Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA.

Biochemistry 2009 Sep;48(35):8299-311

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/bi900982tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752669PMC
September 2009

Synthesis and characterization of modified nucleotides in the 970 hairpin loop of Escherichia coli 16S ribosomal RNA.

Bioorg Med Chem 2009 Aug 9;17(16):5887-93. Epub 2009 Jul 9.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2009.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725200PMC
August 2009

A new role for cisplatin: probing ribosomal RNA structure.

Chem Commun (Camb) 2009 Jan 10(1):107-9. Epub 2008 Nov 10.

Department of Chemistry, Wayne State University, Detroit, Michigan, 48202, USA.

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http://dx.doi.org/10.1039/b816633aDOI Listing
January 2009

Identification of a new alpha1,2-fucosyltransferase involved in O-antigen biosynthesis of Escherichia coli O86:B7 and formation of H-type 3 blood group antigen.

Biochemistry 2008 Nov 9;47(44):11590-7. Epub 2008 Oct 9.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/bi801067sDOI Listing
November 2008

Pseudouridines in rRNA helix 69 play a role in loop stacking interactions.

Org Biomol Chem 2008 Nov 19;6(21):3892-5. Epub 2008 Sep 19.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1039/b812731jDOI Listing
November 2008

Synthesis and solution conformation studies of the modified nucleoside N(4),2'-O-dimethylcytidine (m(4)Cm) and its analogues.

Bioorg Med Chem 2008 Oct 9;16(19):8795-800. Epub 2008 Sep 9.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2008.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583172PMC
October 2008

pH-dependent structural changes of helix 69 from Escherichia coli 23S ribosomal RNA.

RNA 2008 Apr 11;14(4):782-92. Epub 2008 Feb 11.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1261/rna.779908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271367PMC
April 2008

Synthesis and solution conformation studies of 3-substituted uridine and pseudouridine derivatives.

Bioorg Med Chem 2008 Mar 19;16(5):2676-86. Epub 2007 Nov 19.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2007.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2295217PMC
March 2008

Identification and role of functionally important motifs in the 970 loop of Escherichia coli 16S ribosomal RNA.

J Mol Biol 2008 Feb 7;376(3):645-57. Epub 2007 Dec 7.

Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.jmb.2007.11.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262921PMC
February 2008

Characterization of a novel alpha1,2-fucosyltransferase of Escherichia coli O128:b12 and functional investigation of its common motif.

Biochemistry 2008 Jan 14;47(1):378-87. Epub 2007 Dec 14.

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/bi701345vDOI Listing
January 2008

Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications.

ACS Chem Biol 2007 Sep;2(9):610-9

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/cb7001494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535799PMC
September 2007

Monitoring aminoglycoside-induced conformational changes in 16S rRNA through acrylamide quenching.

Bioorg Med Chem 2007 Jun 13;15(11):3825-31. Epub 2007 Mar 13.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/j.bmc.2007.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001229PMC
June 2007

More pronounced salt dependence and higher reactivity for platination of the hairpin r(CGCGUUGUUCGCG) compared with d(CGCGTTGTTCGCG).

J Biol Inorg Chem 2006 Nov 5;11(8):974-90. Epub 2006 Sep 5.

Biochemistry, Chemical Center, Lund University, 221 00, Lund, Sweden.

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http://dx.doi.org/10.1007/s00775-006-0157-yDOI Listing
November 2006

Probing RNA hairpins with cobalt(III)hexammine and electrospray ionization mass spectrometry.

J Am Soc Mass Spectrom 2006 Oct 9;17(10):1376-1382. Epub 2006 Aug 9.

Department of Chemistry, Wayne State University, 5101 Cass Avenue, 48202, Detroit, MI, USA.

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http://link.springer.com/10.1016/j.jasms.2006.07.006
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http://dx.doi.org/10.1016/j.jasms.2006.07.006DOI Listing
October 2006

Solution conformations of two naturally occurring RNA nucleosides: 3-methyluridine and 3-methylpseudouridine.

Bioorg Med Chem 2005 Dec 24;13(24):6777-81. Epub 2005 Aug 24.

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S096808960500726
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http://dx.doi.org/10.1016/j.bmc.2005.07.061DOI Listing
December 2005

NMR conformational analysis of p-tolyl furanopyrimidine 2'-deoxyribonucleoside and crystal structure of its 3',5'-di-O-acetyl derivative.

Bioorg Med Chem 2005 Feb;13(4):1231-8

Department of Chemistry and Center for Biomedical Research, Oakland University, 2200 N. Squirrel Rd, Rochester, MI 48309-4477, USA.

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http://dx.doi.org/10.1016/j.bmc.2004.11.013DOI Listing
February 2005

Sheep red blood cells armed with anti-CD20 single-chain variable fragments (scFvs) fused to a glycosylphosphatidylinositol (GPI) anchor: a strategy to target CD20-positive tumor cells.

J Immunol Methods 2005 Feb 11;297(1-2):109-24. Epub 2005 Jan 11.

Lymphoma Research Laboratory, Department of Internal Medicine, School of Medicine, Wayne State University Detroit, MI 48201, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002217590400427
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http://dx.doi.org/10.1016/j.jim.2004.12.003DOI Listing
February 2005

Synthesis of 15N-enriched pseudouridine derivatives.

Org Lett 2003 Oct;5(22):4093-6

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/ol035496eDOI Listing
October 2003

Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi.

J Org Chem 2002 Dec;67(25):8847-54

Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.

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http://dx.doi.org/10.1021/jo026364mDOI Listing
December 2002

Photoinduced cleavage by a rhodium complex at G.U mismatches and exposed guanines in large and small RNAs.

Biochimie 2002 Sep;84(9):859-68

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/s0300-9084(02)01403-7DOI Listing
September 2002

Design of novel antibiotics that bind to the ribosomal acyltransfer site.

J Am Chem Soc 2002 Apr;124(13):3229-37

Department of Chemistry, Institute for Drug Design, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1021/ja011695mDOI Listing
April 2002

Bcl-2 antisense oligonucleotides are effective against systemic but not central nervous system disease in severe combined immunodeficient mice bearing human t(14;18) follicular lymphoma.

Clin Cancer Res 2002 Apr;8(4):1277-83

Division of Hematology and Oncology, Department of Medicine, Wayne State University, Karmanos Cancer Institute, Detroit, Michigan 48201, USA.

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April 2002

Aminoglycosides modified by resistance enzymes display diminished binding to the bacterial ribosomal aminoacyl-tRNA site.

Chem Biol 2002 Apr;9(4):455-63

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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April 2002

Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin.

Bioorg Med Chem 2002 Feb;10(2):325-32

Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.

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http://dx.doi.org/10.1016/s0968-0896(01)00283-8DOI Listing
February 2002

A Structural Basis for RNAminus signLigand Interactions.

Chem Rev 1997 Aug;97(5):1489-1514

Department of Chemistry, Wayne State University, Detroit, Michigan 48202.

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August 1997