Publications Authored by Christine Allen

Correction to "Codelivery of Paclitaxel and Everolimus at the Optimal Synergistic Ratio: A Promising Solution for the Treatment of Breast Cancer".

Authors:

Loujin Houdaihed James C Evans Christine Allen

Mol Pharm 2019 Oct 23;16(10):4422. Epub 2019 Sep 23.

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b00910	DOI Listing

October 2019

Early Enteral Nutrition Is Associated With Improved Clinical Outcomes in Critically Ill Children: A Secondary Analysis of Nutrition Support in the Heart and Lung Failure-Pediatric Insulin Titration Trial.

Authors:

Vijay Srinivasan Natalie R Hasbani Nilesh M Mehta Sharon Y Irving Sarah B Kandil H Christine Allen Katri V Typpo Natalie Z Cvijanovich E Vincent S Faustino David Wypij Michael S D Agus Vinay M Nadkarni

Pediatr Crit Care Med 2019 Oct 2. Epub 2019 Oct 2.

Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1097/PCC.0000000000002135	DOI Listing

October 2019

Heat-activated drug delivery increases tumor accumulation of synergistic chemotherapies.

Authors:

Michael Dunne Brittany Epp-Ducharme Alexandros Marios Sofias Maximilian Regenold David N Dubins Christine Allen

J Control Release 2019 Aug 11;308:197-208. Epub 2019 Jun 11.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.06.012	DOI Listing

August 2019

Can we overcome the most significant barrier to treatment of neurodegenerative disorders?

Authors:

Christine Allen

J Control Release 2019 Jun 11;303:319-320. Epub 2019 May 11.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.05.014	DOI Listing

June 2019

The question of toxicity of nanomaterials and nanoparticles.

Authors:

Christine Allen

J Control Release 2019 Jun 8;304:288. Epub 2019 Jun 8.

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http://dx.doi.org/10.1016/j.jconrel.2019.06.008	DOI Listing

June 2019

Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children.

Crit Care Med 2019 May;47(5):706-714

Division of Medical Critical Care, Department of Pediatrics, Boston Children's Hospital, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0000000000003699	DOI Listing

May 2019

What do we do next?

Authors:

Christine Allen Kinam Park

J Control Release 2019 May 24;302:203. Epub 2019 Apr 24.

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http://dx.doi.org/10.1016/j.jconrel.2019.04.024	DOI Listing

May 2019

Development of a Bioluminescent BRCA1-Deficient Xenograft Model of Disseminated, High-Grade Serous Ovarian Cancer.

Authors:

Yen Ting Shen Lucy Wang James C Evans Christine Allen Micheline Piquette-Miller

Int J Mol Sci 2019 May 21;20(10). Epub 2019 May 21.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.

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https://www.mdpi.com/1422-0067/20/10/2498	Publisher Site
http://dx.doi.org/10.3390/ijms20102498	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566953	PMC

May 2019

In Vivo Evaluation of Dual-Targeted Nanoparticles Encapsulating Paclitaxel and Everolimus.

Authors:

Loujin Houdaihed James Christopher Evans Christine Allen

Cancers (Basel) 2019 May 29;11(6). Epub 2019 May 29.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, M5S 3M2, Canada.

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http://dx.doi.org/10.3390/cancers11060752	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628352	PMC

May 2019

Lipids and polymers in pharmaceutical technology: Lifelong companions.

Authors:

Juergen Siepmann Amina Faham Sophie-Dorothée Clas Ben J Boyd Vincent Jannin Andreas Bernkop-Schnürch Hang Zhao Sébastien Lecommandoux James C Evans Christine Allen Olivia M Merkel Gabriella Costabile Morgan R Alexander Ricky D Wildman Clive J Roberts Jean-Christophe Leroux

Int J Pharm 2019 Mar 9;558:128-142. Epub 2019 Jan 9.

Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, 8093 Zürich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03785173193001	Publisher Site
http://dx.doi.org/10.1016/j.ijpharm.2018.12.080	DOI Listing

March 2019

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study.

Authors:

Christina Fitzmaurice Tomi F Akinyemiju Faris Hasan Al Lami Tahiya Alam Reza Alizadeh-Navaei Christine Allen Ubai Alsharif Nelson Alvis-Guzman Erfan Amini Benjamin O Anderson Olatunde Aremu Al Artaman Solomon Weldegebreal Asgedom Reza Assadi Tesfay Mehari Atey Leticia Avila-Burgos Ashish Awasthi Huda Omer Ba Saleem Aleksandra Barac James R Bennett Isabela M Bensenor Nickhill Bhakta Hermann Brenner Lucero Cahuana-Hurtado Carlos A Castañeda-Orjuela Ferrán Catalá-López Jee-Young Jasmine Choi Devasahayam Jesudas Christopher Sheng-Chia Chung Maria Paula Curado Lalit Dandona Rakhi Dandona José das Neves Subhojit Dey Samath D Dharmaratne David Teye Doku Tim R Driscoll Manisha Dubey Hedyeh Ebrahimi Dumessa Edessa Ziad El-Khatib Aman Yesuf Endries Florian Fischer Lisa M Force Kyle J Foreman Solomon Weldemariam Gebrehiwot Sameer Vali Gopalani Giuseppe Grosso Rahul Gupta Bishal Gyawali Randah Ribhi Hamadeh Samer Hamidi James Harvey Hamid Yimam Hassen Roderick J Hay Simon I Hay Behzad Heibati Molla Kahssay Hiluf Nobuyuki Horita H Dean Hosgood Olayinka S Ilesanmi Kaire Innos Farhad Islami Mihajlo B Jakovljevic Sarah Charlotte Johnson Jost B Jonas Amir Kasaeian Tesfaye Dessale Kassa Yousef Saleh Khader Ejaz Ahmad Khan Gulfaraz Khan Young-Ho Khang Mohammad Hossein Khosravi Jagdish Khubchandani Jacek A Kopec G Anil Kumar Michael Kutz Deepesh Pravinkumar Lad Alessandra Lafranconi Qing Lan Yirga Legesse James Leigh Shai Linn Raimundas Lunevicius Azeem Majeed Reza Malekzadeh Deborah Carvalho Malta Lorenzo G Mantovani Brian J McMahon Toni Meier Yohannes Adama Melaku Mulugeta Melku Peter Memiah Walter Mendoza Tuomo J Meretoja Haftay Berhane Mezgebe Ted R Miller Shafiu Mohammed Ali H Mokdad Mahmood Moosazadeh Paula Moraga Seyyed Meysam Mousavi Vinay Nangia Cuong Tat Nguyen Vuong Minh Nong Felix Akpojene Ogbo Andrew Toyin Olagunju Mahesh Pa Eun-Kee Park Tejas Patel David M Pereira Farhad Pishgar Maarten J Postma Farshad Pourmalek Mostafa Qorbani Anwar Rafay Salman Rawaf David Laith Rawaf Gholamreza Roshandel Saeid Safiri Hamideh Salimzadeh Juan Ramon Sanabria Milena M Santric Milicevic Benn Sartorius Maheswar Satpathy Sadaf G Sepanlou Katya Anne Shackelford Masood Ali Shaikh Mahdi Sharif-Alhoseini Jun She Min-Jeong Shin Ivy Shiue Mark G Shrime Abiy Hiruye Sinke Mekonnen Sisay Amber Sligar Muawiyyah Babale Sufiyan Bryan L Sykes Rafael Tabarés-Seisdedos Gizachew Assefa Tessema Roman Topor-Madry Tung Thanh Tran Bach Xuan Tran Kingsley Nnanna Ukwaja Vasiliy Victorovich Vlassov Stein Emil Vollset Elisabete Weiderpass Hywel C Williams Nigus Bililign Yimer Naohiro Yonemoto Mustafa Z Younis Christopher J L Murray Mohsen Naghavi

JAMA Oncol 2018 11;4(11):1553-1568

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jamaoncol.2018.2706	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248091	PMC

November 2018

Off-Label Medication use in Children, More Common than We Think: A Systematic Review of the Literature.

Authors:

H Christine Allen M Connor Garbe Julie Lees Naila Aziz Hala Chaaban Jamie L Miller Peter Johnson Stephanie DeLeon

J Okla State Med Assoc 2018 Oct;111(8):776-783

Department of Pediatrics: Section of General and Community Pediatrics, University of Oklahoma College of Medicine, Oklahoma City, OK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677268	PMC

October 2018

Global Burden of Multiple Myeloma: A Systematic Analysis for the Global Burden of Disease Study 2016.

JAMA Oncol 2018 09;4(9):1221-1227

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jamaoncol.2018.2128	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143021	PMC

September 2018

Codelivery of Paclitaxel and Everolimus at the Optimal Synergistic Ratio: A Promising Solution for the Treatment of Breast Cancer.

Authors:

Loujin Houdaihed James C Evans Christine Allen

Mol Pharm 2018 09 14;15(9):3672-3681. Epub 2018 Jun 14.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy , University of Toronto , Toronto M5S 3M2 , Canada.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00217	DOI Listing

September 2018

Manganese-porphyrin-enhanced MRI for the detection of cancer cells: A quantitative in vitro investigation with multiple clinical subtypes of breast cancer.

Authors:

Mosa Alhamami Weiran Cheng Yuanyuan Lyu Christine Allen Xiao-An Zhang Hai-Ling Cheng

PLoS One 2018 24;13(5):e0196998. Epub 2018 May 24.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196998	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993062	PMC

August 2018

Radiation and Heat Improve the Delivery and Efficacy of Nanotherapeutics by Modulating Intratumoral Fluid Dynamics.

Authors:

Shawn Stapleton Michael Dunne Michael Milosevic Charles W Tran Matthew J Gold Ali Vedadi Trevor D Mckee Pamela S Ohashi Christine Allen David A Jaffray

ACS Nano 2018 08 20;12(8):7583-7600. Epub 2018 Jul 20.

Department of Medical Biophysics , University of Toronto , Toronto , ON M5G 1L7 , Canada.

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http://dx.doi.org/10.1021/acsnano.7b06301	DOI Listing

August 2018

Hyperthermia-mediated drug delivery induces biological effects at the tumor and molecular levels that improve cisplatin efficacy in triple negative breast cancer.

Authors:

Michael Dunne Yannan N Dou Danielle M Drake Tara Spence Sávio M L Gontijo Peter G Wells Christine Allen

J Control Release 2018 07 16;282:35-45. Epub 2018 Apr 16.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2018.04.029	DOI Listing

July 2018

BRCA Status Does Not Predict Synergism of a Carboplatin and Olaparib Combination in High-Grade Serous Ovarian Cancer Cell Lines.

Authors:

Yen Ting Shen James C Evans Gaetano Zafarana Christine Allen Micheline Piquette-Miller

Mol Pharm 2018 07 1;15(7):2742-2753. Epub 2018 Jun 1.

Leslie Dan Faculty of Pharmacy , University of Toronto , 144 College Street , Toronto , Ontario M5S 3M2 , Canada.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00246	DOI Listing

July 2018

Factors Controlling Drug Release in Cross-linked Poly(valerolactone) Based Matrices.

Authors:

Frantz Le Devedec Hilary Boucher David Dubins Christine Allen

Mol Pharm 2018 04 2;15(4):1565-1577. Epub 2018 Mar 2.

Leslie Dan Faculty of Pharmacy , University of Toronto , 44 College Street , Ontario M5S 3M2 , Canada.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b01102	DOI Listing

April 2018

Ratio-Dependent Synergism of a Doxorubicin and Olaparib Combination in 2D and Spheroid Models of Ovarian Cancer.

Authors:

Sina Eetezadi James C Evans Yen-Ting Shen Raquel De Souza Micheline Piquette-Miller Christine Allen

Mol Pharm 2018 02 22;15(2):472-485. Epub 2018 Jan 22.

Leslie Dan Faculty of Pharmacy, University of Toronto , 144 College Street, Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00843	DOI Listing

February 2018

The battle of "nano" paclitaxel.

Authors:

Alexandros Marios Sofias Michael Dunne Gert Storm Christine Allen

Adv Drug Deliv Rev 2017 12 28;122:20-30. Epub 2017 Feb 28.

Leslie Dan Faculty of Pharmacy, Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0169409X173003	Publisher Site
http://dx.doi.org/10.1016/j.addr.2017.02.003	DOI Listing

December 2017

The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study 2015.

Authors:

Tomi Akinyemiju Semaw Abera Muktar Ahmed Noore Alam Mulubirhan Assefa Alemayohu Christine Allen Rajaa Al-Raddadi Nelson Alvis-Guzman Yaw Amoako Al Artaman Tadesse Awoke Ayele Aleksandra Barac Isabela Bensenor Adugnaw Berhane Zulfiqar Bhutta Jacqueline Castillo-Rivas Abdulaal Chitheer Jee-Young Choi Benjamin Cowie Lalit Dandona Rakhi Dandona Subhojit Dey Daniel Dicker Huyen Phuc Donatus U. Ekwueme Maysaa El Sayed Zaki Florian Fischer Thomas Fürst Jamie Hancock Simon I. Hay Peter Hotez Sun Ha Jee Amir Kasaeian Yousef Khader Young-Ho Khang Anil Kumar Michael Kutz Heidi Larson Alan Lopez Raimundas Lunevicius Reza Malekzadeh Colm McAlinden Toni Meier Walter Mendoza Ali Mokdad Maziar Moradi-Lakeh Gabriele Nagel Quyen Nguyen Grant Nguyen Felix Ogbo George Patton David M. Pereira Farshad Pourmalek Mostafa Qorbani Amir Radfar Gholamreza Roshandel Joshua A Salomon Juan Sanabria Benn Sartorius Maheswar Satpathy Monika Sawhney Sadaf Sepanlou Katya Shackelford Hirbo Shore Jiandong Sun Desalegn Tadese Mengistu Roman Topór-Mądry Bach Tran Kingsley Nnanna Ukwaja Vasiliy Vlassov Stein Emil Vollset Theo Vos Tolassa Wakayo Elisabete Weiderpass Andrea Werdecker Naohiro Yonemoto Mustafa Younis Chuanhua Yu Zoubida Zaidi Liguo Zhu Christopher J. L. Murray Mohsen Naghavi Christina Fitzmaurice

JAMA Oncol 2017 12;3(12):1683-1691

University of Washington, Institute for Health Metrics and Evaluation, Seattle

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http://dx.doi.org/10.1001/jamaoncol.2017.3055	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824275	PMC

December 2017

Tumor microenvironment determines response to a heat-activated thermosensitive liposome formulation of cisplatin in cervical carcinoma.

Authors:

Yannan N Dou Naz Chaudary Martin C Chang Michael Dunne Huang Huang David A Jaffray Michael Milosevic Christine Allen

J Control Release 2017 Sep 29;262:182-191. Epub 2017 Jul 29.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.07.039	DOI Listing

September 2017

Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?

Authors:

Lei Cui Sohyoung Her Gerben R Borst Robert G Bristow David A Jaffray Christine Allen

Radiother Oncol 2017 09 4;124(3):344-356. Epub 2017 Aug 4.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada; STTARR Innovation Centre, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.radonc.2017.07.007	DOI Listing

September 2017

Overcoming the Road Blocks: Advancement of Block Copolymer Micelles for Cancer Therapy in the Clinic.

Authors:

Loujin Houdaihed James C Evans Christine Allen

Mol Pharm 2017 08 18;14(8):2503-2517. Epub 2017 May 18.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto , Toronto, Ontario, Canada M5S 3M2.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00188	DOI Listing

August 2017

Editorial.

Authors:

Michael R Doschak Christine Allen Emmanuel Ho

Drug Deliv Transl Res 2017 08;7(4):465

University of Manitoba, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1007/s13346-017-0410-7	DOI Listing

August 2017

Intravenous Immunoglobulin Therapy for Cerebral Vasculitis Associated with Rocky Mountain Spotted Fever.

Authors:

H Christine Allen Robert C Welliver Monica W Fogarty Morris Gessouroun Emilie D Henry

J Pediatr Intensive Care 2017 Jun 8;6(2):142-144. Epub 2016 Aug 8.

Section of Pediatric Critical Care, Department of Pediatrics, University of Oklahoma, Oklahoma City, Oklahoma, United States.

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http://dx.doi.org/10.1055/s-0036-1587327	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260288	PMC

June 2017

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study.

Authors:

Christina Fitzmaurice Christine Allen Ryan M Barber Lars Barregard Zulfiqar A Bhutta Hermann Brenner Daniel J Dicker Odgerel Chimed-Orchir Rakhi Dandona Lalit Dandona Tom Fleming Mohammad H Forouzanfar Jamie Hancock Roderick J Hay Rachel Hunter-Merrill Chantal Huynh H Dean Hosgood Catherine O Johnson Jost B Jonas Jagdish Khubchandani G Anil Kumar Michael Kutz Qing Lan Heidi J Larson Xiaofeng Liang Stephen S Lim Alan D Lopez Michael F MacIntyre Laurie Marczak Neal Marquez Ali H Mokdad Christine Pinho Farshad Pourmalek Joshua A Salomon Juan Ramon Sanabria Logan Sandar Benn Sartorius Stephen M Schwartz Katya A Shackelford Kenji Shibuya Jeff Stanaway Caitlyn Steiner Jiandong Sun Ken Takahashi Stein Emil Vollset Theo Vos Joseph A Wagner Haidong Wang Ronny Westerman Hajo Zeeb Leo Zoeckler Foad Abd-Allah Muktar Beshir Ahmed Samer Alabed Noore K Alam Saleh Fahed Aldhahri Girma Alem Mulubirhan Assefa Alemayohu Raghib Ali Rajaa Al-Raddadi Azmeraw Amare Yaw Amoako Al Artaman Hamid Asayesh Niguse Atnafu Ashish Awasthi Huda Ba Saleem Aleksandra Barac Neeraj Bedi Isabela Bensenor Adugnaw Berhane Eduardo Bernabé Balem Betsu Agnes Binagwaho Dube Boneya Ismael Campos-Nonato Carlos Castañeda-Orjuela Ferrán Catalá-López Peggy Chiang Chioma Chibueze Abdulaal Chitheer Jee-Young Choi Benjamin Cowie Solomon Damtew José das Neves Suhojit Dey Samath Dharmaratne Preet Dhillon Eric Ding Tim Driscoll Donatus Ekwueme Aman Yesuf Endries Maryam Farvid Farshad Farzadfar Joao Fernandes Florian Fischer Tsegaye Tewelde G/Hiwot Alemseged Gebru Sameer Gopalani Alemayehu Hailu Masako Horino Nobuyuki Horita Abdullatif Husseini Inge Huybrechts Manami Inoue Farhad Islami Mihajlo Jakovljevic Spencer James Mehdi Javanbakht Sun Ha Jee Amir Kasaeian Muktar Sano Kedir Yousef S Khader Young-Ho Khang Daniel Kim James Leigh Shai Linn Raimundas Lunevicius Hassan Magdy Abd El Razek Reza Malekzadeh Deborah Carvalho Malta Wagner Marcenes Desalegn Markos Yohannes A Melaku Kidanu G Meles Walter Mendoza Desalegn Tadese Mengiste Tuomo J Meretoja Ted R Miller Karzan Abdulmuhsin Mohammad Alireza Mohammadi Shafiu Mohammed Maziar Moradi-Lakeh Gabriele Nagel Devina Nand Quyen Le Nguyen Sandra Nolte Felix A Ogbo Kelechi E Oladimeji Eyal Oren Mahesh Pa Eun-Kee Park David M Pereira Dietrich Plass Mostafa Qorbani Amir Radfar Anwar Rafay Mahfuzar Rahman Saleem M Rana Kjetil Søreide Maheswar Satpathy Monika Sawhney Sadaf G Sepanlou Masood Ali Shaikh Jun She Ivy Shiue Hirbo Roba Shore Mark G Shrime Samuel So Samir Soneji Vasiliki Stathopoulou Konstantinos Stroumpoulis Muawiyyah Babale Sufiyan Bryan L Sykes Rafael Tabarés-Seisdedos Fentaw Tadese Bemnet Amare Tedla Gizachew Assefa Tessema J S Thakur Bach Xuan Tran Kingsley Nnanna Ukwaja Benjamin S Chudi Uzochukwu Vasiliy Victorovich Vlassov Elisabete Weiderpass Mamo Wubshet Terefe Henock Gebremedhin Yebyo Hassen Hamid Yimam Naohiro Yonemoto Mustafa Z Younis Chuanhua Yu Zoubida Zaidi Maysaa El Sayed Zaki Zerihun Menlkalew Zenebe Christopher J L Murray Mohsen Naghavi

JAMA Oncol 2017 Apr;3(4):524-548

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jamaoncol.2016.5688	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103527	PMC

April 2017

To heat or not to heat: Challenges with clinical translation of thermosensitive liposomes.

Authors:

Yannan Dou Kullervo Hynynen Christine Allen

J Control Release 2017 03 22;249:63-73. Epub 2017 Jan 22.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, M5S 3M2, ON, Canada; Physical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute, Toronto, M4N 3M5, ON, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, M5S 3G9, ON, Canada; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, M5S 3E5, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2017.01.025	DOI Listing

March 2017

Use of Simulation to Improve Cardiopulmonary Resuscitation Performance and Code Team Communication for Pediatric Residents.

Authors:

Kevin G Couloures Christine Allen

MedEdPORTAL 2017 Mar 16;13:10555. Epub 2017 Mar 16.

Assistant Professor, Department of Pediatrics, University of Oklahoma College of Medicine.

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http://dx.doi.org/10.15766/mep_2374-8265.10555	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342167	PMC

March 2017

Significant Radiation Enhancement Effects by Gold Nanoparticles in Combination with Cisplatin in Triple Negative Breast Cancer Cells and Tumor Xenografts.

Authors:

Lei Cui Sohyoung Her Michael Dunne Gerben R Borst Raquel De Souza Robert G Bristow David A Jaffray Christine Allen

Radiat Res 2017 02 13;187(2):147-160. Epub 2017 Jan 13.

Departments of a Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy.

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http://dx.doi.org/10.1667/RR14578.1	DOI Listing

February 2017

Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements.

Authors:

Sohyoung Her David A Jaffray Christine Allen

Adv Drug Deliv Rev 2017 01 19;109:84-101. Epub 2015 Dec 19.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada; STTARR Innovation Centre, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2015.12.012	DOI Listing

January 2017

Trends and Patterns of Disparities in Cancer Mortality Among US Counties, 1980-2014.

Authors:

Ali H Mokdad Laura Dwyer-Lindgren Christina Fitzmaurice Rebecca W Stubbs Amelia Bertozzi-Villa Chloe Morozoff Raghid Charara Christine Allen Mohsen Naghavi Christopher J L Murray

JAMA 2017 01;317(4):388-406

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jama.2016.20324	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617139	PMC

January 2017

Radiotherapy for Cancer: Present and Future.

Authors:

Christine Allen Sohyoung Her David A Jaffray

Adv Drug Deliv Rev 2017 Jan;109:1-2

Departments of Radiation Oncology and Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Department of Radiation Physics, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; STTARR Innovation Centre, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Techna Institute, University Health Network, Toronto, Ontario, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.addr.2017.01.004	DOI Listing

January 2017

Thermosensitive liposomal cisplatin in combination with local hyperthermia results in tumor growth delay and changes in tumor microenvironment in xenograft models of lung carcinoma.

Authors:

Yannan Nancy Dou Michael Dunne Huang Huang Trevor Mckee Martin C Chang David A Jaffray Christine Allen

J Drug Target 2016 11 16;24(9):865-877. Epub 2016 Jun 16.

a Leslie Dan Faculty of Pharmacy , University of Toronto , Toronto , ON , Canada.

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http://dx.doi.org/10.1080/1061186X.2016.1191079	DOI Listing

November 2016

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions.

Authors:

Frantz Le Dévédec Loujin Houdaihed Christine Allen

J Vis Exp 2016 10 10(116). Epub 2016 Oct 10.

Leslie Dan Faculty of Pharmacy, University of Toronto;

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http://dx.doi.org/10.3791/54422	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5092180	PMC

October 2016

Why I'm Holding onto Hope for Nano in Oncology.

Authors:

Christine Allen

Mol Pharm 2016 08 15;13(8):2603-4. Epub 2016 Jul 15.

Leslie Dan Faculty of Pharmacy, University of Toronto , 144 College Street Toronto, Ontario, Canada , M5S 3M2.

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http://dx.doi.org/10.1021/acs.molpharmaceut.6b00547	DOI Listing

August 2016

Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors.

Authors:

Shawn Stapleton Daniel Mirmilshteyn Jinzi Zheng Christine Allen David A Jaffray

J Vis Exp 2016 08 18(114). Epub 2016 Aug 18.

Department of Medical Biophysics, University of Toronto; Leslie Dan Faculty of Pharmacy, University of Toronto; STTARR Innovation Centre, Princess Margaret Cancer Centre; Institute of Biomaterials and Biomedical Engineering, University of Toronto; Techna Institute, University Health Network; Radiation Medicine Program, Princess Margaret Cancer Centre.

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http://dx.doi.org/10.3791/54226	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091925	PMC

August 2016

Functionalization of Cellulose Nanocrystals with PEG-Metal-Chelating Block Copolymers via Controlled Conjugation in Aqueous Media.

Authors:

Melinda Guo Sohyoung Her Rachel Keunen Shengmiao Zhang Christine Allen Mitchell A Winnik

ACS Omega 2016 Jul 18;1(1):93-107. Epub 2016 Jul 18.

Department of Chemistry, University of Toronto, 80 Street George Street, Toronto, Ontario M5S 3H6, Canada.

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http://dx.doi.org/10.1021/acsomega.6b00055	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044632	PMC

July 2016

Hydrogels Containing Core Cross-Linked Block Co-Polymer Micelles.

Authors:

Changhai Lu Andrew S Mikhail Xinyue Wang Michael A Brook Christine Allen

J Biomater Sci Polym Ed 2012 ;23(8):1069-90

a Leslie Dan Faculty of Pharmacy, and Department of Chemistry, Faculty of Arts and Science, University of Toronto, 144 College Street, Toronto, ON, Canada M5S 3M2.

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http://dx.doi.org/10.1163/092050611X575414	DOI Listing

June 2016

Dual Action Enhancement of Gold Nanoparticle Radiosensitization by Pentamidine in Triple Negative Breast Cancer.

Authors:

Sohyoung Her Lei Cui Robert G Bristow Christine Allen

Radiat Res 2016 05 2;185(5):549-62. Epub 2016 May 2.

a Departments of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy.

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http://dx.doi.org/10.1667/RR14315.1	DOI Listing

May 2016

The burden of cancer in Mexico, 1990-2013.

Authors:

Héctor Gómez-Dantés Héctor Lamadrid-Figueroa Lucero Cahuana-Hurtado Omar Silverman-Retana Pablo Montero María Cecilia González-Robledo Christina Fitzmaurice Amanda Pain Christine Allen Daniel J Dicker Hannah Hamavid Alan López Christopher Murray Mohsen Naghavi Rafael Lozano

Salud Publica Mex 2016 Apr;58(2):118-31

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April 2016

Vancomycin Dosing and Pharmacokinetics in Postoperative Pediatric Cardiothoracic Surgery Patients.

Authors:

Emily C Benefield Tracy M Hagemann H Christine Allen Kevin Farmer Michael E Burton Susana Chavez-Bueno Peter N Johnson

J Pediatr Pharmacol Ther 2016 Jan-Feb;21(1):66-74

Department of Pharmacy: Clinical and Administrative Sciences, University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma.

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http://dx.doi.org/10.5863/1551-6776-21.1.66	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778698	PMC

March 2016

Integration of imaging into clinical practice to assess the delivery and performance of macromolecular and nanotechnology-based oncology therapies.

Authors:

Tara Spence Raquel De Souza Yannan Dou Shawn Stapleton Raymond M Reilly Christine Allen

J Control Release 2015 Dec 25;219:295-312. Epub 2015 Sep 25.

Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, M5S 3M2, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01683659153013	Publisher Site
http://dx.doi.org/10.1016/j.jconrel.2015.09.036	DOI Listing

December 2015

Preclinical imaging and translational animal models of cancer for accelerated clinical implementation of nanotechnologies and macromolecular agents.

Authors:

Raquel De Souza Tara Spence Huang Huang Christine Allen

J Control Release 2015 Dec 25;219:313-330. Epub 2015 Sep 25.

Leslie Dan Faculty of Pharmacy, 144 College Street, Toronto, Ontario M5S 3M2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2015.09.041	DOI Listing

December 2015

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance.

Authors:

Yannan N Dou Robert A Weersink Warren D Foltz Jinzi Zheng Naz Chaudary David A Jaffray Christine Allen

J Vis Exp 2015 Dec 13(106):e53055. Epub 2015 Dec 13.

Leslie Dan Faculty of Pharmacy, University of Toronto;

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http://dx.doi.org/10.3791/53055	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694025	PMC

December 2015

Effects of Doxorubicin Delivery Systems and Mild Hyperthermia on Tissue Penetration in 3D Cell Culture Models of Ovarian Cancer Residual Disease.

Authors:

Sina Eetezadi Raquel De Souza Mirugashini Vythilingam Rodrigo Lessa Cataldi Christine Allen

Mol Pharm 2015 Nov 2;12(11):3973-85. Epub 2015 Oct 2.

Leslie Dan Faculty of Pharmacy, University of Toronto , 144 College Street, Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00426	DOI Listing

November 2015

A multimodal nano agent for image-guided cancer surgery.

Authors:

Jinzi Zheng Nidal Muhanna Raquel De Souza Hironobu Wada Harley Chan Margarete K Akens Takashi Anayama Kazuhiro Yasufuku Stefano Serra Jonathan Irish Christine Allen David Jaffray

Biomaterials 2015 Oct 14;67:160-8. Epub 2015 Jul 14.

Techna Institute, University Health Network, 100 College Street, Toronto, Ontario, M5G 1P5, Canada; Princess Margaret Cancer Centre, 610 University Avenue, Toronto, Ontario, M5G 2M9, Canada; University of Toronto, Institute of Biomaterials and Biomedical Engineering, 164 College Street, Rm 407, Toronto, Ontario, M5S 3G9, Canada; University of Toronto, Medical Biophysics, 610 University Avenue, Rm 7-411, Toronto, Ontario, M5G 1L7, Canada; University of Toronto, Radiation Oncology, 150 College Street, Rm 106, Toronto, Ontario, M5S 3E2, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01429612150058	Publisher Site
http://dx.doi.org/10.1016/j.biomaterials.2015.07.010	DOI Listing

October 2015

The challenges facing block copolymer micelles for cancer therapy: In vivo barriers and clinical translation.

Authors:

Sina Eetezadi Sandra N Ekdawi Christine Allen

Adv Drug Deliv Rev 2015 Aug 13;91:7-22. Epub 2014 Oct 13.

Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada; Techna Institute, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, 124-100 College Street, Toronto, Ontario M5G 1P5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2014.10.001	DOI Listing

August 2015

The intra-tumoral relationship between microcirculation, interstitial fluid pressure and liposome accumulation.

Authors:

Shawn Stapleton Michael Milosevic Ian F Tannock Christine Allen David A Jaffray

J Control Release 2015 Aug 10;211:163-70. Epub 2015 Jun 10.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; STTARR Innovation Centre, Princess Margaret Cancer Centre, Toronto, ON, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON, Canada; Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada; Techna Institute, University Health Network, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01683659150061	Publisher Site
http://dx.doi.org/10.1016/j.jconrel.2015.06.008	DOI Listing

August 2015

Development of a liposome formulation for improved biodistribution and tumor accumulation of pentamidine for oncology applications.

Authors:

Juliette Mérian Raquel De Souza Yannan Dou Sandra N Ekdawi François Ravenelle Christine Allen

Int J Pharm 2015 Jul 21;488(1-2):154-64. Epub 2015 Apr 21.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2015.04.060	DOI Listing

July 2015

The Global Burden of Cancer 2013.

Authors:

Christina Fitzmaurice Daniel Dicker Amanda Pain Hannah Hamavid Maziar Moradi-Lakeh Michael F MacIntyre Christine Allen Gillian Hansen Rachel Woodbrook Charles Wolfe Randah R Hamadeh Ami Moore Andrea Werdecker Bradford D Gessner Braden Te Ao Brian McMahon Chante Karimkhani Chuanhua Yu Graham S Cooke David C Schwebel David O Carpenter David M Pereira Denis Nash Dhruv S Kazi Diego De Leo Dietrich Plass Kingsley N Ukwaja George D Thurston Kim Yun Jin Edgar P Simard Edward Mills Eun-Kee Park Ferrán Catalá-López Gabrielle deVeber Carolyn Gotay Gulfaraz Khan H Dean Hosgood Itamar S Santos Janet L Leasher Jasvinder Singh James Leigh Jost B Jonas Jost Jonas Juan Sanabria Justin Beardsley Kathryn H Jacobsen Ken Takahashi Richard C Franklin Luca Ronfani Marcella Montico Luigi Naldi Marcello Tonelli Johanna Geleijnse Max Petzold Mark G Shrime Mustafa Younis Naohiro Yonemoto Nicholas Breitborde Paul Yip Farshad Pourmalek Paulo A Lotufo Alireza Esteghamati Graeme J Hankey Raghib Ali Raimundas Lunevicius Reza Malekzadeh Robert Dellavalle Robert Weintraub Robyn Lucas Roderick Hay David Rojas-Rueda Ronny Westerman Sadaf G Sepanlou Sandra Nolte Scott Patten Scott Weichenthal Semaw Ferede Abera Seyed-Mohammad Fereshtehnejad Ivy Shiue Tim Driscoll Tommi Vasankari Ubai Alsharif Vafa Rahimi-Movaghar Vasiliy V Vlassov W S Marcenes Wubegzier Mekonnen Yohannes Adama Melaku Yuichiro Yano Al Artaman Ismael Campos Jennifer MacLachlan Ulrich Mueller Daniel Kim Matias Trillini Babak Eshrati Hywel C Williams Kenji Shibuya Rakhi Dandona Kinnari Murthy Benjamin Cowie Azmeraw T Amare Carl Abelardo Antonio Carlos Castañeda-Orjuela Coen H van Gool Francesco Violante In-Hwan Oh Kedede Deribe Kjetil Soreide Luke Knibbs Maia Kereselidze Mark Green Rosario Cardenas Nobhojit Roy Taavi Tillmann Taavi Tillman Yongmei Li Hans Krueger Lorenzo Monasta Subhojit Dey Sara Sheikhbahaei Nima Hafezi-Nejad G Anil Kumar Chandrashekhar T Sreeramareddy Lalit Dandona Haidong Wang Stein Emil Vollset Ali Mokdad Joshua A Salomon Rafael Lozano Theo Vos Mohammad Forouzanfar Alan Lopez Christopher Murray Mohsen Naghavi

JAMA Oncol 2015 Jul;1(4):505-27

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jamaoncol.2015.0735	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500822	PMC

July 2015

Spatial and temporal mapping of heterogeneity in liposome uptake and microvascular distribution in an orthotopic tumor xenograft model.

Authors:

Sandra N Ekdawi James M P Stewart Michael Dunne Shawn Stapleton Nicholas Mitsakakis Yannan N Dou David A Jaffray Christine Allen

J Control Release 2015 Jun 8;207:101-11. Epub 2015 Apr 8.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01683659150022	Publisher Site
http://dx.doi.org/10.1016/j.jconrel.2015.04.006	DOI Listing

June 2015

(125)I-Labelled 2-Iodoestrone-3-sulfate: synthesis, characterization and OATP mediated transport studies in hormone dependent and independent breast cancer cells.

Authors:

Nilasha Banerjee T Robert Wu Jason Chio Ryan Kelly Karin A Stephenson John Forbes Christine Allen John F Valliant Reina Bendayan

Nucl Med Biol 2015 Mar 8;42(3):274-82. Epub 2014 Nov 8.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.nucmedbio.2014.10.011	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673477	PMC

March 2015

Hypoxia and cellular localization influence the radiosensitizing effect of gold nanoparticles (AuNPs) in breast cancer cells.

Authors:

Lei Cui Kenneth Tse Payam Zahedi Shane M Harding Gaetano Zafarana David A Jaffray Robert G Bristow Christine Allen

Radiat Res 2014 Nov 31;182(5):475-88. Epub 2014 Oct 31.

a Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://www.bioone.org/doi/10.1667/RR13642.1	Publisher Site
http://dx.doi.org/10.1667/RR13642.1	DOI Listing

November 2014

A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors.

Authors:

Shawn Stapleton Michael Milosevic Christine Allen Jinzi Zheng Michael Dunne Ivan Yeung David A Jaffray

PLoS One 2013 2;8(12):e81157. Epub 2013 Dec 2.

Department of Medical Biophysics, University of Toronto, Ontario, Canada ; STTARR Innovation Centre, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081157	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846845	PMC

August 2014

Expression of membrane transporters and metabolic enzymes involved in estrone-3-sulphate disposition in human breast tumour tissues.

Authors:

Nilasha Banerjee Naomi Miller Christine Allen Reina Bendayan

Breast Cancer Res Treat 2014 Jun 16;145(3):647-61. Epub 2014 May 16.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON, M5S 3M2, Canada.

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http://dx.doi.org/10.1007/s10549-014-2990-y	DOI Listing

June 2014

Estrone-3-sulphate, a potential novel ligand for targeting breast cancers.

Authors:

Nilasha Banerjee Humphrey Fonge Andrew Mikhail Raymond M Reilly Reina Bendayan Christine Allen

PLoS One 2013 22;8(5):e64069. Epub 2013 May 22.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064069	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661587	PMC

April 2014

Image-based analysis of the size- and time-dependent penetration of polymeric micelles in multicellular tumor spheroids and tumor xenografts.

Authors:

Andrew S Mikhail Sina Eetezadi Sandra N Ekdawi James Stewart Christine Allen

Int J Pharm 2014 Apr 17;464(1-2):168-77. Epub 2014 Jan 17.

Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario M5S 3E1, Canada; Spatio-Temporal Targeting and Amplification Radiation Response (STTARR) Innovation Centre, 101 College Street, Toronto, Ontario M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2014.01.010	DOI Listing

April 2014

The impact of sustained and intermittent docetaxel chemotherapy regimens on cognition and neural morphology in healthy mice.

Authors:

Joanna E Fardell Ji Zhang Raquel De Souza Janette Vardy Ian Johnston Christine Allen Jeffrey Henderson Micheline Piquette-Miller

Psychopharmacology (Berl) 2014 Mar 8;231(5):841-52. Epub 2013 Oct 8.

School of Psychology, The University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1007/s00213-013-3301-8	DOI Listing

March 2014

Heat-activated thermosensitive liposomal cisplatin (HTLC) results in effective growth delay of cervical carcinoma in mice.

Authors:

Yannan N Dou Jinzi Zheng Warren D Foltz Robert Weersink Naz Chaudary David A Jaffray Christine Allen

J Control Release 2014 Mar 15;178:69-78. Epub 2014 Jan 15.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada; STTARR Innovation Center, University Health Network, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2014.01.009	DOI Listing

March 2014

A novel minimally invasive technique to create a rabbit VX2 lung tumor model for nano-sized image contrast and interventional studies.

Authors:

Takashi Anayama Takahiro Nakajima Michael Dunne Jinzi Zheng Christine Allen Brandon Driscoll Douglass Vines Shaf Keshavjee David Jaffray Kazuhiro Yasufuku

PLoS One 2013 28;8(6):e67355. Epub 2013 Jun 28.

Division of Thoracic Surgery, Department of Surgery, Toronto General Hospital, University of Toronto, University Health Network, Toronto, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067355	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696117	PMC

January 2014

Multi-arm PEG/silica hydrogel for sustained ocular drug delivery.

Authors:

Changhai Lu Payam Zahedi Adam Forman Christine Allen

J Pharm Sci 2014 Jan 27;103(1):216-26. Epub 2013 Nov 27.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jps.23777	DOI Listing

January 2014

Multicellular tumor spheroids for evaluation of cytotoxicity and tumor growth inhibitory effects of nanomedicines in vitro: a comparison of docetaxel-loaded block copolymer micelles and Taxotere®.

Authors:

Andrew S Mikhail Sina Eetezadi Christine Allen

PLoS One 2013 23;8(4):e62630. Epub 2013 Apr 23.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062630	PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633836	PMC

November 2013

Tumor perfusion imaging predicts the intra-tumoral accumulation of liposomes.

Authors:

Shawn Stapleton Christine Allen Melania Pintilie David A Jaffray

J Control Release 2013 Nov 7;172(1):351-357. Epub 2013 Sep 7.

TECHNA Institute and Ontario Cancer Institute, University Health Network, Toronto, Canada; Radiation Medicine Program, Princess Margaret Cancer Centre, Toronto, Canada; Departments of Radiation Oncology, Medical Biophysics, and IBBME, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.jconrel.2013.08.296	DOI Listing

November 2013

Active targeting of block copolymer micelles with trastuzumab Fab fragments and nuclear localization signal leads to increased tumor uptake and nuclear localization in HER2-overexpressing xenografts.

Authors:

Bryan Hoang Sandra N Ekdawi Raymond M Reilly Christine Allen

Mol Pharm 2013 Nov 22;10(11):4229-41. Epub 2013 Oct 22.

Leslie Dan Faculty of Pharmacy, ‡Department of Chemistry, and §Department of Medical Imaging, University of Toronto , 144 College St., Toronto, Ontario, M5S 3M2, Canada.

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http://dx.doi.org/10.1021/mp400315p	DOI Listing

November 2013

Thermosensitive depot-forming injectable phosphatidylcholine blends tailored for localized drug delivery.

Authors:

Justin Grant Payam Zahedi Antonia Tsallas Christine Allen

J Pharm Sci 2013 Oct 19;102(10):3623-31. Epub 2013 Jul 19.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jps.23664	DOI Listing

October 2013

Continuous intraperitoneal carboplatin delivery for the treatment of late-stage ovarian cancer.

Authors:

Nickholas Zhidkov Raquel De Souza Amir H Ghassemi Christine Allen Micheline Piquette-Miller

Mol Pharm 2013 Sep 21;10(9):3315-22. Epub 2013 Aug 21.

Department of Pharmaceutical Sciences, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1021/mp400345h	DOI Listing

September 2013

Implementation of a bowel regimen protocol in critically ill children: A pilot study.

Authors:

Megan G Andrews Jamie L Miller Christine Allen Tracy M Hagemann Donald L Harrison Peter N Johnson

J Pediatr Intensive Care 2013 Jun;2(2):63-69

Clinical and Administrative Sciences, Department of Pharmacy, College of Pharmacy, University of Oklahoma, Oklahoma City, OK, USA.

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http://dx.doi.org/10.3233/PIC-13051	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530715	PMC

June 2013

Comparison of computed tomography- and optical image-based assessment of liposome distribution.

Authors:

Huang Huang Michael Dunne John Lo David A Jaffray Christine Allen

Mol Imaging 2013 May;12(3):148-60

Leslie Dan Faculty of Pharmacy, Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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May 2013

Neoplastic cell response to tiopronin-coated gold nanoparticles.

Authors:

Lei Cui Payam Zahedi Justin Saraceno Robert Bristow David Jaffray Christine Allen

Nanomedicine 2013 Feb 9;9(2):264-73. Epub 2012 Jun 9.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.nano.2012.05.016	DOI Listing

February 2013

Hydrogel containing silica shell cross-linked micelles for ocular drug delivery.

Authors:

Changhai Lu Roshan B Yoganathan Michael Kociolek Christine Allen

J Pharm Sci 2013 Feb 30;102(2):627-37. Epub 2012 Nov 30.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1002/jps.23390	DOI Listing

February 2013

Differential role of organic anion-transporting polypeptides in estrone-3-sulphate uptake by breast epithelial cells and breast cancer cells.

Authors:

Nilasha Banerjee Christine Allen Reina Bendayan

J Pharmacol Exp Ther 2012 Aug 15;342(2):510-9. Epub 2012 May 15.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, ON, Canada M5S 3M2.

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http://jpet.aspetjournals.org/content/342/2/510.full.pdf	Web Search
http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.112.19234	Publisher Site
http://dx.doi.org/10.1124/jpet.112.192344	DOI Listing

August 2012

Recent advances in drug delivery strategies for treatment of ovarian cancer.

Authors:

Payam Zahedi Roshan Yoganathan Micheline Piquette-Miller Christine Allen

Expert Opin Drug Deliv 2012 May 27;9(5):567-83. Epub 2012 Mar 27.

University of Toronto, Leslie Dan Faculty of Pharmacy , 144 College Street, Toronto, Ontario M5S-3M2 , Canada.

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http://dx.doi.org/10.1517/17425247.2012.665366	DOI Listing

May 2012

An injectable depot system for sustained intraperitoneal chemotherapy of ovarian cancer results in favorable drug distribution at the whole body, peritoneal and intratumoral levels.

Authors:

Payam Zahedi James Stewart Raquel De Souza Micheline Piquette-Miller Christine Allen

J Control Release 2012 Mar 26;158(3):379-85. Epub 2011 Nov 26.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jconrel.2011.11.025	DOI Listing

March 2012

Influence of formulation variables on the biodistribution of multifunctional block copolymer micelles.

Authors:

Humphrey Fonge Huang Huang Deborah Scollard Raymond M Reilly Christine Allen

J Control Release 2012 Feb 1;157(3):366-74. Epub 2011 Oct 1.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.jconrel.2011.09.088	DOI Listing

February 2012

Block copolymer micelles target Auger electron radiotherapy to the nucleus of HER2-positive breast cancer cells.

Authors:

Bryan Hoang Raymond M Reilly Christine Allen

Biomacromolecules 2012 Feb 17;13(2):455-65. Epub 2012 Jan 17.

Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, Canada M5S 3M2.

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http://pubs.acs.org/doi/10.1021/bm201479t	Publisher Site
http://dx.doi.org/10.1021/bm201479t	DOI Listing

February 2012

Computational approaches to the rational design of nanoemulsions, polymeric micelles, and dendrimers for drug delivery.

Authors:

Loan Huynh Chris Neale Régis Pomès Christine Allen

Nanomedicine 2012 Jan 25;8(1):20-36. Epub 2011 May 25.

Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S154996341100178	Publisher Site
http://dx.doi.org/10.1016/j.nano.2011.05.006	DOI Listing

January 2012

APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes.

Authors:

Michael Dunne Jinzi Zheng Joshua Rosenblat David A Jaffray Christine Allen

J Control Release 2011 Sep 27;154(3):298-305. Epub 2011 May 27.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.jconrel.2011.05.022	DOI Listing

September 2011

Docetaxel distribution following intraperitoneal administration in mice.

Authors:

Payam Zahedi Raquel De Souza Micheline Piquette-Miller Christine Allen

J Pharm Pharm Sci 2011 ;14(1):90-9

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

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August 2011

Chemotherapy dosing schedule influences drug resistance development in ovarian cancer.

Authors:

Raquel De Souza Payam Zahedi Rose M Badame Christine Allen Micheline Piquette-Miller

Mol Cancer Ther 2011 Jul 6;10(7):1289-99. Epub 2011 May 6.

Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, Ontario, Canada M5S 3M2.

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http://dx.doi.org/10.1158/1535-7163.MCT-11-0058	DOI Listing

July 2011

Combination drug delivery strategy for the treatment of multidrug resistant ovarian cancer.

Authors:

Payam Zahedi Raquel De Souza Loan Huynh Micheline Piquette-Miller Christine Allen

Mol Pharm 2011 Feb 17;8(1):260-9. Epub 2010 Dec 17.

Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1021/mp100323z	DOI Listing

February 2011

Liposome contrast agent for CT-based detection and localization of neoplastic and inflammatory lesions in rabbits: validation with FDG-PET and histology.

Authors:

Jinzi Zheng Christine Allen Stefano Serra Douglass Vines Martin Charron David A Jaffray

Contrast Media Mol Imaging 2010 May-Jun;5(3):147-54

Department Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/cmmi.378	Publisher Site
http://dx.doi.org/10.1002/cmmi.378	DOI Listing

January 2011

In vivo distribution of polymeric nanoparticles at the whole-body, tumor, and cellular levels.

Authors:

Helen Lee Bryan Hoang Humphrey Fonge Raymond M Reilly Christine Allen

Pharm Res 2010 Nov 2;27(11):2343-55. Epub 2010 Mar 2.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College St., Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s11095-010-0068-z	DOI Listing

November 2010

Polymeric drug delivery systems for localized cancer chemotherapy.

Authors:

Raquel De Souza Payam Zahedi Christine J Allen Micheline Piquette-Miller

Drug Deliv 2010 Aug;17(6):365-75

Department of Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, Ontario, M5S-3M2, Canada.

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http://www.tandfonline.com/doi/full/10.3109/1071754100376285	Publisher Site
http://dx.doi.org/10.3109/10717541003762854	DOI Listing

August 2010

The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles.

Authors:

Helen Lee Humphrey Fonge Bryan Hoang Raymond M Reilly Christine Allen

Mol Pharm 2010 Aug;7(4):1195-208

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, Division of Nuclear Medicine, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1021/mp100038h	DOI Listing

August 2010

Utility of transdermal fentanyl for prevention of iatrogenic opioid abstinence syndrome in children.

Authors:

Peter N Johnson Donald Harrison Christine Allen

J Opioid Manag 2010 Mar-Apr;6(2):117-24

University of Oklahoma College of Medicine, Oklahoma City, Oklahoma, USA.

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June 2010

Gold nanoparticles as radiation sensitizers in cancer therapy.

Authors:

Devika B Chithrani Salomeh Jelveh Farid Jalali Monique van Prooijen Christine Allen Robert G Bristow Richard P Hill David A Jaffray

Radiat Res 2010 Jun;173(6):719-28

STTARR Innovation Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1667/RR1984.1	DOI Listing

June 2010

Continuous docetaxel chemotherapy improves therapeutic efficacy in murine models of ovarian cancer.

Authors:

Raquel De Souza Payam Zahedi Eduardo H Moriyama Christine J Allen Brian C Wilson Micheline Piquette-Miller

Mol Cancer Ther 2010 Jun 8;9(6):1820-30. Epub 2010 Jun 8.

Department of Pharmaceutical Sciences, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0249	DOI Listing

June 2010

Poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles containing chemically conjugated and physically entrapped docetaxel: synthesis, characterization, and the influence of the drug on micelle morphology.

Authors:

Andrew S Mikhail Christine Allen

Biomacromolecules 2010 May;11(5):1273-80

Leslie Dan Faculty of Pharmacy, Institute of Biomaterials and Biomedical Engineering, University of Toronto 144 College Street, Toronto, Ontario, Canada M5S 3M2.

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