Christina Curtis

Christina Curtis

UNVERIFIED PROFILE

Are you Christina Curtis?   Register this Author

Register author
Christina Curtis

Christina Curtis

Publications by authors named "Christina Curtis"

Are you Christina Curtis?   Register this Author

58Publications

1786Reads

7Profile Views

Quantitative evidence for early metastatic seeding in colorectal cancer.

Nat Genet 2019 Jul 17;51(7):1113-1122. Epub 2019 Jun 17.

Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0423-xDOI Listing
July 2019

Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data.

Nat Genet 2018 09;50(9):1342

Evolution and Cancer Laboratory, Barts Cancer Institute, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0169-xDOI Listing
September 2018

A role for chromatin regulatory dynamics in breast cancer evolution.

Nat Med 2018 09;24(9):1309-1311

Department of Genetics, Stanford University School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41591-018-0182-8DOI Listing
September 2018

Harnessing Tumor Evolution to Circumvent Resistance.

Trends Genet 2018 08 11;34(8):639-651. Epub 2018 Jun 11.

Cancer Biology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; http://med.stanford.edu/curtislab.html. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2018.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368975PMC
August 2018

Quantification of subclonal selection in cancer from bulk sequencing data.

Nat Genet 2018 06 28;50(6):895-903. Epub 2018 May 28.

Evolution and Cancer Laboratory, Barts Cancer Institute, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0128-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475346PMC
June 2018

Big Bang Tumor Growth and Clonal Evolution.

Cold Spring Harb Perspect Med 2018 05 1;8(5). Epub 2018 May 1.

Departments of Medicine and Genetics, Stanford University School of Medicine, Stanford, California 94305.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a028381DOI Listing
May 2018

AGBT meeting report.

Genome Biol 2018 05 21;19(1):60. Epub 2018 May 21.

Departments of Medicine and Genetics, Stanford University School of Medicine, Stanford, CA, 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-018-1447-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963147PMC
May 2018

Organoids reveal cancer dynamics.

Nature 2018 04;556(7702):441-442

View Article

Download full-text PDF

Source
http://www.nature.com/articles/d41586-018-03841-x
Publisher Site
http://dx.doi.org/10.1038/d41586-018-03841-xDOI Listing
April 2018

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.

Cancer Cell 2017 10;32(4):460-473.e6

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659188PMC
October 2017

Early mutation bursts in colorectal tumors.

PLoS One 2017 3;12(3):e0172516. Epub 2017 Mar 3.

Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172516PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336211PMC
August 2017

Between-region genetic divergence reflects the mode and tempo of tumor evolution.

Nat Genet 2017 Jul 5;49(7):1015-1024. Epub 2017 Jun 5.

Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643198PMC
July 2017

Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells.

Cancer Res 2017 04 13;77(7):1575-1585. Epub 2017 Jan 13.

Divisions of Gastroenterology and Hematology/Oncology, Department of Medicine, University of California, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-16-0512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410377PMC
April 2017

A population genetics perspective on the determinants of intra-tumor heterogeneity.

Biochim Biophys Acta Rev Cancer 2017 Apr 6;1867(2):109-126. Epub 2017 Mar 6.

Departments of Medicine and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbcan.2017.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623098PMC
April 2017

Inferring Tumor Phylogenies from Multi-region Sequencing.

Cell Syst 2016 07;3(1):12-4

Departments of Medicine and Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

View Article

Download full-text PDF

Source
http://www.cell.com/cell-systems/pdf/S2405-4712(16)30224-1.p
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S240547121630224
Publisher Site
http://dx.doi.org/10.1016/j.cels.2016.07.007DOI Listing
July 2016

Many private mutations originate from the first few divisions of a human colorectal adenoma.

J Pathol 2015 Nov 3;237(3):355-62. Epub 2015 Aug 3.

Department of Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/path.4581
Publisher Site
http://dx.doi.org/10.1002/path.4581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607608PMC
November 2015

A Big Bang model of human colorectal tumor growth.

Nat Genet 2015 Mar 9;47(3):209-16. Epub 2015 Feb 9.

Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575589PMC
March 2015

Genomic profiling of breast cancers.

Authors:
Christina Curtis

Curr Opin Obstet Gynecol 2015 Feb;27(1):34-9

Departments of Medicine and Genetics, Stanford University School of Medicine and Stanford Cancer Institute, Stanford, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/GCO.0000000000000145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497788PMC
February 2015

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.

Mol Oncol 2015 Jan 8;9(1):115-27. Epub 2014 Aug 8.

Cancer Research UK, Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK; Department of Oncology, University of Cambridge, Hills Road, Cambridge CB2 2XZ, UK; Cambridge Experimental Cancer Medicine Centre, Cambridge CB2 0RE, UK; Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge University Hospital NHS Foundation Trust and NIHR Cambridge Biomedical Research Centre, Cambridge CB2 2QQ, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molonc.2014.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286124PMC
January 2015

The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31.

Mol Cell 2014 Mar 27;53(5):806-18. Epub 2014 Feb 27.

Gurdon Institute and Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2014.01.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988886PMC
March 2014

Precise inference of copy number alterations in tumor samples from SNP arrays.

Bioinformatics 2013 Dec 9;29(23):2964-70. Epub 2013 Sep 9.

Department of Preventive Medicine, Zilkha Neurogenetic Institute and Department of Psychiatry, University of Southern California, Los Angeles, CA 90089, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btt521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834792PMC
December 2013

The shaping and functional consequences of the microRNA landscape in breast cancer.

Nature 2013 May 5;497(7449):378-82. Epub 2013 May 5.

Cancer Research UK Cambridge Institute and Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature12108DOI Listing
May 2013

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

Proc Natl Acad Sci U S A 2013 Mar 14;110(10):4009-14. Epub 2013 Feb 14.

Department of Oncology, University of Cambridge, Cambridge CB2 2XZ, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1219747110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593922PMC
March 2013

A sparse regulatory network of copy-number driven gene expression reveals putative breast cancer oncogenes.

IEEE/ACM Trans Comput Biol Bioinform 2012 Jul-Aug;9(4):947-54

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TCBB.2011.105DOI Listing
October 2012

Penalized regression elucidates aberration hotspots mediating subtype-specific transcriptional responses in breast cancer.

Bioinformatics 2011 Oct 30;27(19):2679-85. Epub 2011 Jul 30.

Cambridge Research Institute, Cancer Research UK, Li Ka Shing Centre, Cambridge CB2 0RE, UK.

View Article

Download full-text PDF

Source
https://academic.oup.com/bioinformatics/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btr450DOI Listing
October 2011

The pitfalls of platform comparison: DNA copy number array technologies assessed.

BMC Genomics 2009 Dec 8;10:588. Epub 2009 Dec 8.

Department of Oncology, University of Cambridge, Addenbrooke's Hopsital, Hills Road, Cambridge CB20XZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-10-588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797821PMC
December 2009

Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy.

Aging (Albany NY) 2009 Oct 27;1(11):903-36. Epub 2009 Oct 27.

Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089-2910, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815744PMC
http://dx.doi.org/10.18632/aging.100099DOI Listing
October 2009

Swift: primary data analysis for the Illumina Solexa sequencing platform.

Bioinformatics 2009 Sep 23;25(17):2194-9. Epub 2009 Jun 23.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btp383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734321PMC
September 2009

A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila.

Aging (Albany NY) 2009 Jan 30;1(2):191-211. Epub 2009 Jan 30.

Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806004PMC
http://dx.doi.org/10.18632/aging.100018DOI Listing
January 2009

Explaining differences in saturation levels for Affymetrix GeneChip arrays.

Nucleic Acids Res 2007 12;35(12):4154-63. Epub 2007 Jun 12.

Department of Human Genetics, University of California Los Angeles, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkm348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919478PMC
August 2007

Scambio, a novel guanine nucleotide exchange factor for Rho.

Mol Cancer 2004 Apr 23;3:10. Epub 2004 Apr 23.

Division of Hematology/Oncology, Section of Molecular Carcinogenesis, Childrens Hospital Los Angeles Research Institute and the Keck School of Medicine of the University of Southern California, Los Angeles, California 90027, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1476-4598-3-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420252PMC
April 2004