Publications by authors named "Christie P Thomas"

61Publications

Correction: Initial experience from a renal genetics clinic demonstrates a distinct role in patient management.

Genet Med 2020 Oct 6. Epub 2020 Oct 6.

Departments of Internal Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1038/s41436-020-01000-0DOI Listing
October 2020

Spontaneous remission of genetic, apparent primary, FSGS presenting with nephrotic syndrome challenges traditional notions of primary FSGS.

J Nephrol 2020 Aug 27. Epub 2020 Aug 27.

Division of Nephrology, Departments of Internal Medicine, SE419 GH, University of Iowa Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA, 52242, USA.

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http://dx.doi.org/10.1007/s40620-020-00837-7DOI Listing
August 2020

A rare case of hyporeninemic hypertension: Answers.

Pediatr Nephrol 2020 Jun 30. Epub 2020 Jun 30.

Pediatric Nephrology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1007/s00467-020-04667-4DOI Listing
June 2020

A rare case of hyporeninemic hypertension: Questions.

Pediatr Nephrol 2020 Jun 30. Epub 2020 Jun 30.

Pediatric Nephrology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1007/s00467-020-04658-5DOI Listing
June 2020

Estimated Glomerular Filtration Rate at Transplant Listing and Other Predictors of Post-Heart Transplant Mortality and the Development of ESRD.

Transplantation 2020 Nov;104(11):2444-2452

Department of Internal Medicine, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1097/TP.0000000000003159DOI Listing
November 2020

Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines.

Transpl Int 2019 Dec 8;32(12):1268-1276. Epub 2019 Oct 8.

Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1111/tri.13520DOI Listing
December 2019

Billing for living kidney donor care: Balancing cost recovery, regulatory compliance, and minimized donor burden.

Curr Transplant Rep 2019 Jun 27;6(2):155-166. Epub 2019 Apr 27.

American Society of Transplantation (AST) Living Donor Community of Practice (LDCOP).

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http://dx.doi.org/10.1007/s40472-019-00239-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580854PMC
June 2019

Diagnosis of monogenic chronic kidney diseases.

Curr Opin Nephrol Hypertens 2019 03;28(2):183-194

Division of Nephrology, Department of Internal Medicine.

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http://dx.doi.org/10.1097/MNH.0000000000000486DOI Listing
March 2019

VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis.

Am J Physiol Cell Physiol 2018 08 2;315(2):C214-C224. Epub 2018 May 2.

Department of Internal Medicine, University of Iowa Carver College of Medicine , Iowa City, Iowa.

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http://dx.doi.org/10.1152/ajpcell.00247.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139503PMC
August 2018

EGF regulation of proximal tubule cell proliferation and VEGF-A secretion.

Physiol Rep 2017 Sep 27;5(18). Epub 2017 Sep 27.

Division of Pediatric Nephrology, Stead Family Department of Pediatrics, Dialysis and Transplantation, University of Iowa Carver College of Medicine, Iowa City, Iowa.

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http://dx.doi.org/10.14814/phy2.13453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617933PMC
September 2017

Aldosterone regulates a 5' variant sgk1 transcript via a shared hormone response element in the sgk1 5' regulatory region.

Physiol Rep 2017 Apr;5(7)

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa

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http://dx.doi.org/10.14814/phy2.13221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392512PMC
April 2017

Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene.

Mol Immunol 2016 09 1;77:89-96. Epub 2016 Aug 1.

Molecular Otolaryngology and Renal Research Laboratories, Caver College of Medicine, University of Iowa, Iowa City, IA, USA; Interdepartmental PhD Program in Genetics, Caver College of Medicine, University of Iowa, Iowa City, IA, USA; Departments of Pediatrics and Internal Medicine, Divisions of Nephrology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Iowa Institute of Human Genetics, Caver College of Medicine, University of Iowa, Iowa City, IA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2016.07.007DOI Listing
September 2016

Has the Department of Veterans Affairs Found a Way to Avoid Racial Disparities in the Evaluation Process for Kidney Transplantation?

Transplantation 2017 06;101(6):1191-1199

1 Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 2 Center for Bioethics and Health Law, University of Pittsburgh, Pittsburgh, PA. 3 Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. 4 Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, PA. 5 Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. 6 Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA. 7 Department of Psychology, University of Pittsburgh, Pittsburgh, PA. 8 Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. 9 Renal Section, Tennessee Valley VA Healthcare System, Nashville, TN. 10 Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 11 Kaiser Permanente, Northwest, Portland, OR. 12 Portland Center for the Study of Chronic, Comorbid Mental and Physical Disorders, Portland VA Medical Center, Portland, OR. 13 Department of Medicine, Oregon Health and Science University, Portland, OR. 14 Renal Section, Pittsburgh VA Healthcare System, Pittsburgh, PA. 15 Renal Section, Iowa City VA Healthcare System, Iowa City, IA. 16 Department of Medicine, University of Iowa Carver College of Medicine, Iowa City, IA.

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http://dx.doi.org/10.1097/TP.0000000000001377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288397PMC
June 2017

Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage.

Exp Cell Res 2016 05 23;344(1):103-111. Epub 2016 Mar 23.

Departments of Internal Medicine, University of Iowa Carver College, United States; Departments of Pediatrics, University of Iowa Carver College, United States; Departments of Obstetrics, University of Iowa Carver College, United States; Program in Molecular and Cellular Biology, University of Iowa Carver College of Medicine, United States; Departments of Veterans Affairs Medical Center, Iowa City, IA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2016.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879079PMC
May 2016

BK polyoma virus infection and renal disease in non-renal solid organ transplantation.

Clin Kidney J 2016 Apr 30;9(2):310-8. Epub 2015 Dec 30.

Department of Internal Medicine, University of Iowa, Carver College of Medicine, Iowa City, IA, USA; VA Medical Center, Iowa City, IA, USA.

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http://dx.doi.org/10.1093/ckj/sfv143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792618PMC
April 2016

Eculizumab for rescue of thrombotic microangiopathy in PM-Scl antibody-positive autoimmune overlap syndrome.

Clin Kidney J 2015 Dec 13;8(6):698-701. Epub 2015 Oct 13.

Division of Immunology, Department of Internal Medicine , Carver College of Medicine, The University of Iowa , Iowa City, IA , USA.

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http://dx.doi.org/10.1093/ckj/sfv101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655803PMC
December 2015

Primary Cutaneous Polymorphic EBV-Associated Posttransplant Lymphoproliferative Disorder After a Renal Transplant and Review of the Literature.

Am J Dermatopathol 2015 Oct;37(10):790-4

Departments of *Dermatology, †Medicine and VA Medical Center, ‡Medicine and Pharmacology, and §Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA.

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http://dx.doi.org/10.1097/DAD.0000000000000272DOI Listing
October 2015

The challenge in diagnosing de novo minimal change disease after transplantation.

Transplantation 2015 Feb;99(2):e11-2

1 University of Iowa Hospitals and Clinics, Iowa City, IA. 2 VA Medical Center, Iowa City, IA.

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http://dx.doi.org/10.1097/TP.0000000000000550DOI Listing
February 2015

N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain.

PLoS One 2014 11;9(11):e112794. Epub 2014 Nov 11.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, United States of America; Department of Molecular and Cellular Biology, University of Iowa College of Medicine, Iowa City, IA, United States of America; Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA, United States of America; Department of Obstetrics, University of Iowa College of Medicine, Iowa City, IA, United States of America; Veterans Affairs Medical Center, Iowa City, IA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112794PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227870PMC
March 2016

Quiz page April 2013: recurrent episodes of acute kidney injury in a kidney transplant recipient.

Am J Kidney Dis 2013 Apr;61(4):A22-4

Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1053/j.ajkd.2012.12.020DOI Listing
April 2013

Atypical hemolytic uremic syndrome: what is it, how is it diagnosed, and how is it treated?

Hematology Am Soc Hematol Educ Program 2012 ;2012:617-25

Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1182/asheducation-2012.1.617DOI Listing
June 2013

A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct.

Am J Physiol Renal Physiol 2012 Dec 3;303(11):F1527-33. Epub 2012 Oct 3.

Dept. of Internal Medicine, Univ. of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1152/ajprenal.00191.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532487PMC
December 2012

Dextran removal by plasmapheresis in a kidney-pancreas transplant recipient with dextran 40-induced osmotic nephrosis.

Am J Kidney Dis 2011 Apr 22;57(4):621-3. Epub 2011 Jan 22.

Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1053/j.ajkd.2010.10.057DOI Listing
April 2011

Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia.

Am J Physiol Renal Physiol 2010 Aug 26;299(2):F436-44. Epub 2010 May 26.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, 52242, USA.

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http://dx.doi.org/10.1152/ajprenal.00674.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928518PMC
August 2010

Alternate processing of Flt1 transcripts is directed by conserved cis-elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation.

Nucleic Acids Res 2010 Aug 12;38(15):5130-40. Epub 2010 Apr 12.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USA.

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http://dx.doi.org/10.1093/nar/gkq198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926593PMC
August 2010

Recurrent atypical hemolytic uremic syndrome associated with factor I mutation in a living related renal transplant recipient.

Am J Kidney Dis 2009 Feb 21;53(2):321-6. Epub 2008 Sep 21.

Department of Medicine, Section of Nephrology, University of Wisconsin Hospitals and Clinics, Madison, WI, USA.

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http://dx.doi.org/10.1053/j.ajkd.2008.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879708PMC
February 2009

An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.

Am J Physiol Renal Physiol 2008 Nov 27;295(5):F1440-8. Epub 2008 Aug 27.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USA.

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http://www.physiology.org/doi/10.1152/ajprenal.90239.2008
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http://dx.doi.org/10.1152/ajprenal.90239.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653283PMC
November 2008

A genetic syndrome of chronic renal failure with multiple renal cysts and early onset diabetes.

Kidney Int 2008 Oct 4;74(8):1094-9. Epub 2008 Jun 4.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1038/ki.2008.227DOI Listing
October 2008

Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel.

Am J Physiol Renal Physiol 2008 May 5;294(5):F1157-65. Epub 2008 Mar 5.

Department of Internal Medicine, E300 GH, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1152/ajprenal.00339.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424110PMC
May 2008

Intronic polyadenylation signal sequences and alternate splicing generate human soluble Flt1 variants and regulate the abundance of soluble Flt1 in the placenta.

FASEB J 2007 Dec 5;21(14):3885-95. Epub 2007 Jul 5.

Department of Internal Medicine and Graduate Program in Molecular and Cellular Biology, E300 GH, University of Iowa Carver College of Medicine, 200 Hawkins Dr., Iowa City, IA 52242-1081 USA.

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http://dx.doi.org/10.1096/fj.07-8809comDOI Listing
December 2007

Diffuse glomerular crescents and peritubular immune deposits in a transplant kidney.

Am J Kidney Dis 2006 Jul;48(1):174-8

Department of Pathology, University of Iowa Carver College of Medicine and Veterans Affairs Medical Center, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1053/j.ajkd.2006.04.064DOI Listing
July 2006

Medroxyprogesterone acetate binds the glucocorticoid receptor to stimulate alpha-ENaC and sgk1 expression in renal collecting duct epithelia.

Am J Physiol Renal Physiol 2006 Feb 27;290(2):F306-12. Epub 2005 Sep 27.

Division of Nephrology, Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242-1081, USA.

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http://dx.doi.org/10.1152/ajprenal.00062.2005DOI Listing
February 2006

Nedd4-2 isoforms differentially associate with ENaC and regulate its activity.

Am J Physiol Renal Physiol 2005 Aug 5;289(2):F334-46. Epub 2005 Apr 5.

Department of Internal Medicine, University of Iowa, Iowa City, 52242, USA.

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http://dx.doi.org/10.1152/ajprenal.00394.2004DOI Listing
August 2005

Early postnephrectomy donor renal function: laparoscopic versus open procedure.

Transplantation 2005 Mar;79(5):609-12

Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242-1081, USA.

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http://dx.doi.org/10.1097/01.tp.0000151662.84962.4eDOI Listing
March 2005

New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis.

Curr Opin Nephrol Hypertens 2004 Sep;13(5):541-8

Department of Internal Medicine and the Graduate Program in Molecular Biology, University of Iowa College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1097/00041552-200409000-00010DOI Listing
September 2004

cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1.

Am J Physiol Lung Cell Mol Physiol 2004 Oct 18;287(4):L843-51. Epub 2004 Jun 18.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1152/ajplung.00340.2003DOI Listing
October 2004

AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5'-flanking region of the VIT32 gene.

Am J Physiol Renal Physiol 2004 Sep 12;287(3):F460-8. Epub 2004 May 12.

Department of Internal Medicine, Graduate Program in Molecular Biology, University of Iowa College of Medicine, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1152/ajprenal.00107.2004DOI Listing
September 2004

Transcriptional repression of the CTP:phosphocholine cytidylyltransferase gene by sphingosine.

Biochem J 2004 Sep;382(Pt 2):741-50

Department of Veterans Affairs Medical Center, University of Iowa College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1042/BJ20040105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133833PMC
September 2004

Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains.

Am J Physiol Renal Physiol 2003 Nov 22;285(5):F916-29. Epub 2003 Jul 22.

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, USA.

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http://dx.doi.org/10.1152/ajprenal.00203.2003DOI Listing
November 2003

Cycloheximide increases glucocorticoid-stimulated alpha -ENaC mRNA in collecting duct cells by p38 MAPK-dependent pathway.

Am J Physiol Renal Physiol 2003 Apr 27;284(4):F778-87. Epub 2002 Dec 27.

Department of Internal Medicine, and Graduate Program in Molecular Biology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1152/ajprenal.00088.2002DOI Listing
April 2003

Glucocorticoids stimulate human sgk1 gene expression by activation of a GRE in its 5'-flanking region.

Am J Physiol Endocrinol Metab 2002 Nov;283(5):E971-9

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52246, USA.

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http://dx.doi.org/10.1152/ajpendo.00021.2002DOI Listing
November 2002

Systemic pseudohypoaldosteronism from deletion of the promoter region of the human Beta epithelial na(+) channel subunit.

Am J Respir Cell Mol Biol 2002 Sep;27(3):314-9

Department of Internal Medicine, University of Iowa, Iowa City, Iowa 52242-1081, USA.

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http://dx.doi.org/10.1165/rcmb.2002-0029OCDOI Listing
September 2002

Genomic organization of the 5' end of human beta-ENaC and preliminary characterization of its promoter.

Am J Physiol Renal Physiol 2002 May;282(5):F898-909

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242-1081, USA.

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http://dx.doi.org/10.1152/ajprenal.00268.2001DOI Listing
May 2002

Glucocorticoid-stimulated lung epithelial Na(+) transport is associated with regulated ENaC and sgk1 expression.

Am J Physiol Lung Cell Mol Physiol 2002 Apr;282(4):L631-41

Department of Internal Medicine, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1152/ajplung.00085.2001DOI Listing
April 2002