Christian Wolfrum

Christian Wolfrum

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Christian Wolfrum

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A Genetic Model to Study the Contribution of Brown and Brite Adipocytes to Metabolism.

Cell Rep 2020 Mar;30(10):3424-3433.e4

Institute of Food Nutrition and Health and Department of Health Sciences and Technology, Eidgenössische Technische Hochschule Zürich (ETH), 8603 Schwerzenbach, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.02.055DOI Listing
March 2020

Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism.

Endocr Rev 2020 Jan;41(1)

Institute of Food, Nutrition, and Health, ETH Zürich, Schorenstrasse, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1210/endrev/bnz007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006230PMC
January 2020

Proliferation of nutrition sensing preadipocytes upon short term HFD feeding.

Adipocyte 2019 12 29;8(1):16-25. Epub 2018 Sep 29.

a Institute of Food Nutrition and Health , Eidgenössische Technische Hochschule Zürich (ETH) , Schwerzenbach , Switzerland.

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http://dx.doi.org/10.1080/21623945.2018.1521229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768278PMC
December 2019

Antioxidants protect against diabetes by improving glucose homeostasis in mouse models of inducible insulin resistance and obesity.

Diabetologia 2019 11 15;62(11):2094-2105. Epub 2019 Jul 15.

Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Swiss Federal Institute of Technology, ETH Zürich, CH-8603, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1007/s00125-019-4937-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805816PMC
November 2019

Puerariae lobatae root extracts and the regulation of brown fat activity.

Phytomedicine 2019 Nov 23;64:153075. Epub 2019 Aug 23.

HanseMerkur Center for Traditional Chinese Medicine at the University Medical Center Hamburg-Eppendorf, Breitenfelder Straße 15, D-20251 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2019.153075DOI Listing
November 2019

Maternal overnutrition leads to cognitive and neurochemical abnormalities in C57BL/6 mice.

Nutr Neurosci 2019 Oct 1;22(10):688-699. Epub 2018 Feb 1.

Laboratory of Translational Nutrition Biology, ETH Zurich , Schwerzenbach , Switzerland.

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http://dx.doi.org/10.1080/1028415X.2018.1432096DOI Listing
October 2019

Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis.

EMBO Mol Med 2019 10 6;11(10):e10124. Epub 2019 Jun 6.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland.

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http://dx.doi.org/10.15252/emmm.201810124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783644PMC
October 2019

Lessons from Cre-Mice and Indicator Mice.

Handb Exp Pharmacol 2019 ;251:37-54

Institute of Food, Nutrition, and Health, ETH Zurich, Zürich, Switzerland.

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http://dx.doi.org/10.1007/164_2018_146DOI Listing
July 2019

Statins: benefits and risks revisited.

Aging (Albany NY) 2019 07;11(13):4300-4302

Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach 8603, Switzerland.

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http://dx.doi.org/10.18632/aging.102056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660028PMC
July 2019

Identification of chemotypes in bitter melon by metabolomics: a plant with potential benefit for management of diabetes in traditional Chinese medicine.

Metabolomics 2019 07 18;15(8):104. Epub 2019 Jul 18.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, CMU - Rue Michel-Servet 1, CH-1206, Geneva 4, Switzerland.

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http://dx.doi.org/10.1007/s11306-019-1565-7DOI Listing
July 2019

Liver ASK1 protects from non-alcoholic fatty liver disease and fibrosis.

EMBO Mol Med 2019 Jun 6. Epub 2019 Jun 6.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland

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http://dx.doi.org/10.15252/emmm.201810124DOI Listing
June 2019

Environmental and Nutritional Effects Regulating Adipose Tissue Function and Metabolism Across Generations.

Adv Sci (Weinh) 2019 Jun 16;6(11):1900275. Epub 2019 Apr 16.

Department of Health Science and Technologies ETH Zürich Schorenstrasse 16 Schwerzenbach CH-8603 Switzerland.

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http://dx.doi.org/10.1002/advs.201900275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548959PMC
June 2019

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs.

Proc Natl Acad Sci U S A 2019 05 6;116(21):10547-10556. Epub 2019 May 6.

Laboratory of Translational Nutrition Biology, Department of Health Sciences and Technology, ETH Zurich, 8603 Schwerzenbach, Switzerland;

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http://dx.doi.org/10.1073/pnas.1820810116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534971PMC
May 2019

ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer.

Nat Commun 2019 04 18;10(1):1809. Epub 2019 Apr 18.

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland.

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http://www.nature.com/articles/s41467-019-09803-9
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http://dx.doi.org/10.1038/s41467-019-09803-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472429PMC
April 2019

Fat cells with a sweet tooth.

Nature 2019 01;565(7738):167-168

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http://www.nature.com/articles/d41586-018-07739-6
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http://dx.doi.org/10.1038/d41586-018-07739-6DOI Listing
January 2019

TRPC1 regulates brown adipose tissue activity in a PPARγ-dependent manner.

Am J Physiol Endocrinol Metab 2018 11 10;315(5):E825-E832. Epub 2018 Jul 10.

Center for Transgenic Models, University of Basel , Basel , Switzerland.

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https://www.physiology.org/doi/10.1152/ajpendo.00170.2017
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http://dx.doi.org/10.1152/ajpendo.00170.2017DOI Listing
November 2018

Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition.

Transl Psychiatry 2018 10 12;8(1):195. Epub 2018 Oct 12.

Laboratory of Translational Nutrition Biology, Department of Health Sciences and Technology, ETH Zurich, 8603, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1038/s41398-018-0243-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185972PMC
October 2018

Weight Loss and Adipose Tissue Browning in Humans: The Chicken or the Egg?

Trends Endocrinol Metab 2018 07 13;29(7):450-452. Epub 2018 Mar 13.

Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, Swiss Federal Institute of Technology, ETH Zürich, CH-8603 Schwerzenbach, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2018.03.004DOI Listing
July 2018

A stromal cell population that inhibits adipogenesis in mammalian fat depots.

Nature 2018 07 20;559(7712):103-108. Epub 2018 Jun 20.

Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL) and Swiss Institute of Bioinformatics, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41586-018-0226-8DOI Listing
July 2018

Hemostasis, endothelial stress, inflammation, and the metabolic syndrome.

Semin Immunopathol 2018 02 5;40(2):215-224. Epub 2017 Dec 5.

Institute of Food, Nutrition and Health, ETH Zurich, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1007/s00281-017-0666-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809518PMC
February 2018

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

Atherosclerosis 2017 10 4;265:197-206. Epub 2017 Sep 4.

Institute of Laboratory Medicine, Ludwig Maximilians University Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.08.030DOI Listing
October 2017

SRF and MKL1 Independently Inhibit Brown Adipogenesis.

PLoS One 2017 26;12(1):e0170643. Epub 2017 Jan 26.

Swiss Federal Institute of Technology, ETH Zürich, Institute of Food Nutrition and Health, Schwerzenbach, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170643PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268445PMC
August 2017

Adipocytes at the Core of Bone Function.

Cell Stem Cell 2017 06;20(6):739-740

ETH Zürich, Schorenstrasse 16, CH-8603 Schwerzenbach, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.05.008DOI Listing
June 2017

The dual role of BMP4 in adipogenesis and metabolism.

Adipocyte 2017 04 6;6(2):141-146. Epub 2017 Feb 6.

a Swiss Federal Institute of Technology, Department of Health Science , Institute of Food Nutrition and Health, Laboratory of Translational Nutrition Biology , Schwerzenbach , Switzerland.

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http://dx.doi.org/10.1080/21623945.2017.1287637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477726PMC
April 2017

Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice.

Arterioscler Thromb Vasc Biol 2017 Feb 22;37(2):247-257. Epub 2016 Dec 22.

From the Institute of Laboratory Medicine (A.N., B.H.N., K.S., A.H., A.K., D.T., L.M.H.) and Institute for Cardiovascular Prevention (Z.Z., C.Weber, S.S.), Ludwig-Maximilians-University Munich, Germany; Institute of Biochemistry, Christian Albrechts University, Kiel, Germany (A.C., S.R.-J.); Institute of Food, Nutrition and Health, ETH Zurich, Schwerzenbach, Switzerland (C.Wolfrum); and German Centre for Cardiovascular Research, partner site Munich Heart Alliance, Germany (C. Weber, S.S.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308682DOI Listing
February 2017

A high-throughput, image-based screen to identify kinases involved in brown adipocyte development.

Sci Signal 2017 02 14;10(466). Epub 2017 Feb 14.

Institute of Food, Nutrition and Health, ETH-Zürich, Schorenstrasse 16, CH-8603 Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1126/scisignal.aaf5357DOI Listing
February 2017

Adipose-derived circulating miRNAs regulate gene expression in other tissues.

Nature 2017 02 15;542(7642):450-455. Epub 2017 Feb 15.

Section on Integrative Physiology &Metabolism, Joslin Diabetes Center and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nature21365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330251PMC
February 2017

LSD1 Makes Fat Colorful.

Trends Endocrinol Metab 2017 01 1;28(1):1-2. Epub 2016 Nov 1.

Institute of Food, Nutrition, and Health, Eidgenössische Technische Hochschule (ETH) Zürich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2016.10.006DOI Listing
January 2017

Liver ubiquitome uncovers nutrient-stress-mediated trafficking and secretion of complement C3.

Cell Death Dis 2016 10 13;7(10):e2411. Epub 2016 Oct 13.

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Centre National de la Recherche Scientifique UMR 7104, Institut National de la Santé et de la Recherche Médicale U964, Université de Strasbourg, Illkirch 67404, France.

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http://dx.doi.org/10.1038/cddis.2016.312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133979PMC
October 2016

Regulation of adipogenesis by paracrine factors from adipose stromal-vascular fraction - a link to fat depot-specific differences.

Biochim Biophys Acta 2016 09 16;1861(9 Pt A):1121-1131. Epub 2016 Jun 16.

Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2016.06.010DOI Listing
September 2016

Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice.

Sci Rep 2016 08 11;6:31566. Epub 2016 Aug 11.

Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.1038/srep31566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980670PMC
August 2016

Bmp4 Promotes a Brown to White-like Adipocyte Shift.

Cell Rep 2016 08 11;16(8):2243-2258. Epub 2016 Aug 11.

Swiss Federal Institute of Technology, Department of Health Science, Institute of Food Nutrition and Health, Laboratory of Translational Nutrition Biology, Schwerzenbach 8603, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.048DOI Listing
August 2016

Anatomical Grading for Metabolic Activity of Brown Adipose Tissue.

PLoS One 2016 22;11(2):e0149458. Epub 2016 Feb 22.

Department of Nuclear Medicine, University Hospital of Zurich, Zurich, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149458PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762683PMC
July 2016

Adipose Tissue Stem Cells.

Handb Exp Pharmacol 2016 ;233:251-63

ETH Zürich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1007/164_2015_13DOI Listing
June 2016

Regulation of De Novo Adipocyte Differentiation Through Cross Talk Between Adipocytes and Preadipocytes.

Diabetes 2015 Dec 4;64(12):4075-87. Epub 2015 Sep 4.

Institute of Food, Nutrition and Health, ETH Zurich, Schwerzenbach, Switzerland

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http://dx.doi.org/10.2337/db14-1932DOI Listing
December 2015

FGF21, energy expenditure and weight loss - How much brown fat do you need?

Mol Metab 2015 Sep 25;4(9):605-9. Epub 2015 Jun 25.

Swiss Federal Institute of Technology, ETH Zürich, Institute of Food Nutrition and Health, Schorenstr. 16, 8603 Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1016/j.molmet.2015.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563019PMC
September 2015

Optimization and scale-up of oligonucleotide synthesis in packed bed reactors using computational fluid dynamics modeling.

Biotechnol Prog 2014 Sep-Oct;30(5):1048-56. Epub 2014 Aug 8.

Eckart GmbH Werk Wackersdorf, Boschstraße 1, 92442, Wackersdorf, Germany.

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http://dx.doi.org/10.1002/btpr.1966DOI Listing
June 2015

Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.

Circulation 2015 Mar 11;131(10):871-81. Epub 2015 Feb 11.

From Centre for Molecular Cardiology, University of Zurich and University Heart Center, Cardiology, University Hospital Zurich, Switzerland (E.O., P.D., S.S., J.M., U.L., C.M.M., T.F.L.); Institute of Veterinary Physiology, University of Zurich, Switzerland (P.D., C.C., C.D., H.B., K.S., T.A.L.); Department of Surgery (M.B., D.V.) and Institute of Clinical Chemistry (L.R., R.H.), University Hospital Zurich, Switzerland; Université Lille 2, INSERM UMR1011, EGID, Institut Pasteur de Lille, France (S.C., A.T., B.S.); Department of Health Sciences and Technology, ETH Zurich, Switzerland (C.W.); Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Italy (F.T.); State Key Laboratory for Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, University of Hong Kong, SAR (P.M.V.); and Department of Endocrine Surgery, Lille University Hospital, France (F.P.).

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http://circ.ahajournals.org/content/early/2015/02/11/CIRCULA
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http://www.swisscardio.ch/public/jahrestagung/programm/Prese
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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011791DOI Listing
March 2015

Chronic high-fat diet impairs collecting lymphatic vessel function in mice.

PLoS One 2014 8;9(4):e94713. Epub 2014 Apr 8.

Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology, ETH Zurich, Zurich, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094713PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979858PMC
December 2014

Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network.

Elife 2014 Aug 27;3:e03346. Epub 2014 Aug 27.

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland.

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http://dx.doi.org/10.7554/eLife.03346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359378PMC
August 2014

Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes.

Peptides 2014 Jun 16;56:1-7. Epub 2014 Mar 16.

Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia; Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01969781140007
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http://dx.doi.org/10.1016/j.peptides.2014.03.003DOI Listing
June 2014

The origin and definition of brite versus white and classical brown adipocytes.

Adipocyte 2014 Jan 28;3(1):4-9. Epub 2013 Aug 28.

Institute of Food Nutrition and Health; ETH Zürich; Schwerzenbach, Switzerland.

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http://dx.doi.org/10.4161/adip.26232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917931PMC
January 2014

Phenotypic Analysis of BAT versus WAT Differentiation.

Curr Protoc Mouse Biol 2013 Dec 19;3(4):205-16. Epub 2013 Dec 19.

Institute of Food, Nutrition, and Health, ETH Zurich, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1002/9780470942390.mo130167DOI Listing
December 2013

Longitudinal evaluation of hepatic lipid deposition and composition in ob/ob and ob/+ control mice.

NMR Biomed 2013 Sep 28;26(9):1079-88. Epub 2013 Jan 28.

Institute for Biomedical Engineering, ETH Zürich and University of Zürich, Switzerland.

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http://doi.wiley.com/10.1002/nbm.2921
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http://dx.doi.org/10.1002/nbm.2921DOI Listing
September 2013

Transcriptional regulation of adipocyte formation by the liver receptor homologue 1 (Lrh1)-Small hetero-dimerization partner (Shp) network.

Mol Metab 2013 16;2(3):314-23. Epub 2013 Mar 16.

Swiss Federal Institute of Technology, ETH Zürich, Competence Centre for Systems Physiology (CC-SPMD), Institute of Food Nutrition and Health, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1016/j.molmet.2013.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773829PMC
September 2013

A radical opposition in body weight control.

EMBO Mol Med 2013 Aug;5(8):1147-8

Laboratory for Energy Metabolism, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/emmm.201303094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944455PMC
August 2013

Malfunctioning of adipocytes in obesity is linked to quantitative surfaceome changes.

Biochim Biophys Acta 2013 Jul;1831(7):1208-16

Institute of Molecular Systems Biology, ETH Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.bbalip.2013.04.001DOI Listing
July 2013

Bi-directional interconversion of brite and white adipocytes.

Nat Cell Biol 2013 Jun 28;15(6):659-67. Epub 2013 Apr 28.

Institute of Food, Nutrition and Health, ETH Zurich, Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1038/ncb2740DOI Listing
June 2013

Bone morphogenic proteins signaling in adipogenesis and energy homeostasis.

Biochim Biophys Acta 2013 May 23;1831(5):915-23. Epub 2013 Jan 23.

Institute of Food, Nutrition and Health, ETH Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.bbalip.2013.01.010DOI Listing
May 2013

Transcriptional cofactor TBLR1 controls lipid mobilization in white adipose tissue.

Cell Metab 2013 Apr 14;17(4):575-85. Epub 2013 Mar 14.

Joint Division Molecular Metabolic Control, DKFZ-ZMBH Alliance and Network Aging Research, German Cancer Research Center (DKFZ) Heidelberg, Center for Molecular Biology (ZMBH) and University Hospital, Heidelberg University, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.cmet.2013.02.010DOI Listing
April 2013

Hepatic lipid composition differs between ob/ob and ob/+ control mice as determined by using in vivo localized proton magnetic resonance spectroscopy.

MAGMA 2012 Oct 23;25(5):381-9. Epub 2012 Mar 23.

Institute for Biomedical Engineering UZH/ETH, University and ETH Zurich, HIT E22.4, Wolfgang-Pauli-Strasse 27, 8093, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s10334-012-0310-2DOI Listing
October 2012

TaqIA polymorphism in dopamine D2 receptor gene complicates weight maintenance in younger obese patients.

Nutrition 2012 Oct 25;28(10):996-1001. Epub 2012 Apr 25.

Department of Medicine I and Clinical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.nut.2011.12.018DOI Listing
October 2012

Maternal high-fat diet in mice programs emotional behavior in adulthood.

Behav Brain Res 2012 Aug 23;233(2):398-404. Epub 2012 May 23.

The Swiss Federal Institute of Technology, ETH Zürich, Institute of Food Nutrition and Health, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1016/j.bbr.2012.05.027DOI Listing
August 2012

Regulation of adipocyte formation by GLP-1/GLP-1R signaling.

J Biol Chem 2012 Feb 29;287(9):6421-30. Epub 2011 Dec 29.

Swiss Federal Institute of Technology, ETH Zürich, Institute of Food Nutrition and Health, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1074/jbc.M111.310342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307265PMC
February 2012

Synthetic inositol phosphoglycans related to GPI lack insulin-mimetic activity.

ACS Chem Biol 2010 Nov;5(11):1075-86

Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, Germany.

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http://dx.doi.org/10.1021/cb1002152DOI Listing
November 2010

Regulation of adaptive behaviour during fasting by hypothalamic Foxa2.

Nature 2009 Dec;462(7273):646-50

The Rockefeller University, Laboratory of Metabolic Diseases, 1230 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nature08589DOI Listing
December 2009

Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M.

J Biol Chem 2008 Jun 1;283(24):16940-9. Epub 2008 Apr 1.

Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, Eidgenössische Technische Hochschule Zürich, 8093 Zürich, Switzerland.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M801930200
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http://dx.doi.org/10.1074/jbc.M801930200DOI Listing
June 2008

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

Nat Biotechnol 2007 Oct 16;25(10):1149-57. Epub 2007 Sep 16.

Institute of Molecular Systems Biology, Swiss Federal Institute of Technology, ETH Zürich, HPT E73.

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http://dx.doi.org/10.1038/nbt1339DOI Listing
October 2007

Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion.

Cell Metab 2006 Feb;3(2):99-110

Laboratory of Metabolic Diseases, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.cmet.2006.01.001DOI Listing
February 2006

Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis.

Nat Med 2005 Apr 27;11(4):418-22. Epub 2005 Mar 27.

The Laboratory of Metabolic Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

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http://www.nature.com/articles/nm1211
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http://dx.doi.org/10.1038/nm1211DOI Listing
April 2005

Large-scale purification of oligonucleotides by extraction and precipitation with butanole.

Biotechnol Bioeng 2005 Mar;89(5):551-5

identif GmbH, Ulrich-Schalk-Str. 3, D-91056 Erlangen, Germany.

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http://dx.doi.org/10.1002/bit.20378DOI Listing
March 2005

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.

Nature 2004 Dec;432(7020):1027-32

Laboratory of Metabolic Diseases, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

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http://www.nature.com/articles/nature03047
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http://dx.doi.org/10.1038/nature03047DOI Listing
December 2004