Publications by authors named "Christian Vokuhl"

72Publications

SP8 Promotes an Aggressive Phenotype in Hepatoblastoma via FGF8 Activation.

Cancers (Basel) 2020 Aug 15;12(8). Epub 2020 Aug 15.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, 80337 Munich, Germany.

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http://dx.doi.org/10.3390/cancers12082294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465460PMC
August 2020

Patterns of Prior and Subsequent Neoplasms in Children and Adolescents With Soft Tissue Sarcomas.

J Pediatr Hematol Oncol 2020 Jul;42(5):e265-e270

Department of Pediatric and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University Medical Center Freiburg, University of Freiburg.

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http://dx.doi.org/10.1097/MPH.0000000000001837DOI Listing
July 2020

Dermatofibrosarcoma protuberans in children and adolescents: Primary and Relapsed disease-Experience of the Cooperative Weichteilsarkomstudiengruppe (CWS).

J Surg Oncol 2020 Aug 19;122(2):263-272. Epub 2020 May 19.

Klinikum Stuttgart-Olgahospital, Stuttgart Cancer Center, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart, Germany.

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http://dx.doi.org/10.1002/jso.25943DOI Listing
August 2020

High expression of IGF2-derived intronic miR-483 predicts outcome in hepatoblastoma.

Cancer Biomark 2020 ;28(3):321-328

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.3233/CBM-191390DOI Listing
January 2020

Immunophenotype-Genotype Correlations in Clear Cell Sarcoma of Kidney-An Evaluation of Diagnostic Ancillary Studies.

Pediatr Dev Pathol 2020 Sep-Oct;23(5):345-351. Epub 2020 May 4.

Trinity College, University of Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1177/1093526620910658DOI Listing
May 2020

Downregulation of SFRP1 is a protumorigenic event in hepatoblastoma and correlates with beta-catenin mutations.

J Cancer Res Clin Oncol 2020 May 18;146(5):1153-1167. Epub 2020 Mar 18.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, LMU Munich, Lindwurmstr. 2a, 80337, Munich, Germany.

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http://dx.doi.org/10.1007/s00432-020-03182-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142044PMC
May 2020

Kaposiform hemangioendothelioma and tufted angioma - (epi)genetic analysis including genome-wide methylation profiling.

Ann Diagn Pathol 2020 Feb 10;44:151434. Epub 2019 Dec 10.

Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands; Princess Màxima Center for Pediatric Oncology, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2019.151434DOI Listing
February 2020

The impact of local control in the treatment of children with advanced infantile and adult-type fibrosarcoma: Experience of the cooperative weichteilsarkom studiengruppe (CWS).

J Pediatr Surg 2020 Sep 9;55(9):1740-1747. Epub 2019 Nov 9.

Klinikum Stuttgart - Olgahospital, Stuttgart Cancer Center, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart, Germany; Children's Hospital, Department of Pediatric Hematology and Oncology, Tuebingen, Germany.

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http://dx.doi.org/10.1016/j.jpedsurg.2019.10.051DOI Listing
September 2020

High-risk blastemal Wilms tumor can be modeled by 3D spheroid cultures in vitro.

Oncogene 2020 Jan 27;39(4):849-861. Epub 2019 Sep 27.

Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1038/s41388-019-1027-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976522PMC
January 2020

Treatment and outcome of patients with thoracic tumors of the Ewing sarcoma family: A report from the Cooperative Weichteilsarkom Studiengruppe CWS-81, -86, -91, -96, and -2002P trials.

Pediatr Blood Cancer 2019 08;66 Suppl 3:e27884

Klinikum Stuttgart - Olgahospital, Stuttgart Cancer Center, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart, Germany.

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http://dx.doi.org/10.1002/pbc.27884DOI Listing
August 2019

Calcifying fibrous tumor and inflammatory myofibroblastic tumor are epigenetically related: A comparative genome-wide methylation study.

Ann Diagn Pathol 2019 Aug 3;41:102-105. Epub 2019 Jun 3.

Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2019.05.013DOI Listing
August 2019

Activation of Hedgehog Signaling in Aggressive Hepatic Hemangioma in Newborns and Infants.

Anticancer Res 2019 May;39(5):2351-2360

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

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http://dx.doi.org/10.21873/anticanres.13352DOI Listing
May 2019

Chromosomal gains of 12p and 1q are not associated with inferior outcome of pediatric and adolescent germ cell tumors.

Pediatr Blood Cancer 2019 08 2;66(8):e27777. Epub 2019 May 2.

Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel, Kiel, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pbc.27777
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http://dx.doi.org/10.1002/pbc.27777DOI Listing
August 2019

Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells.

Int J Oncol 2019 May 5;54(5):1853-1863. Epub 2019 Mar 5.

Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, D‑80337 Munich, Germany.

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http://dx.doi.org/10.3892/ijo.2019.4741DOI Listing
May 2019

Treatment and outcome of patients with thoracic tumors of the Ewing sarcoma family: A report from the Cooperative Weichteilsarkom Studiengruppe CWS-81, -86, -91, -96, and -2002P trials.

Pediatr Blood Cancer 2019 03 12;66(3):e27537. Epub 2018 Nov 12.

Klinikum Stuttgart - Olgahospital, Stuttgart Cancer Center, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart, Germany.

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http://doi.wiley.com/10.1002/pbc.27537
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http://dx.doi.org/10.1002/pbc.27537DOI Listing
March 2019

Expression profiles of pro-inflammatory and pro-apoptotic mediators in secondary tethered cord syndrome after myelomeningocele repair surgery.

Childs Nerv Syst 2019 02 3;35(2):315-328. Epub 2018 Oct 3.

Department of Neurosurgery, University Hospital of Schleswig-Holstein Campus Kiel, Arnold-Heller-Str. 3, House 41, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s00381-018-3984-6DOI Listing
February 2019

Alveolar soft-part sarcoma: Primary metastatic disease and metastatic relapse occurring during long-term follow-up: Treatment results of four Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry.

Pediatr Blood Cancer 2018 12 19;65(12):e27405. Epub 2018 Aug 19.

Klinikum Stuttgart-Olgahospital, Stuttgart Cancer Center, Zentrum für Kinder-, Jugend-und Frauenmedizin, Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart, Germany.

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http://doi.wiley.com/10.1002/pbc.27405
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http://dx.doi.org/10.1002/pbc.27405DOI Listing
December 2018

Größenprogredienter Tumor an der lateralen Thoraxwand bei einem 14-jährigen Jungen.

J Dtsch Dermatol Ges 2018 May;16(5):640-643

Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel.

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http://dx.doi.org/10.1111/ddg.13428_gDOI Listing
May 2018

Interferon beta induces apoptosis in nasopharyngeal carcinoma cells the TRAIL-signaling pathway.

Oncotarget 2018 Mar 12;9(18):14228-14250. Epub 2018 Feb 12.

Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.18632/oncotarget.24479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865666PMC
March 2018

Overexpression of promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma.

Clin Epigenetics 2018 2;10:27. Epub 2018 Mar 2.

1Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Lindwurmstr. 2a, 80337 Munich, Germany.

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https://clinicalepigeneticsjournal.biomedcentral.com/article
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http://dx.doi.org/10.1186/s13148-018-0462-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833129PMC
February 2019

Inflammatory myofibroblastic tumors-A retrospective analysis of the Cooperative Weichteilsarkom Studiengruppe.

Pediatr Blood Cancer 2018 06 26;65(6):e27012. Epub 2018 Feb 26.

Pediatrics 5 (Oncology, Hematology, and Immunology), Stuttgart Cancer Center, Klinikum Stuttgart, Olgahospital, Stuttgart, Germany.

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http://doi.wiley.com/10.1002/pbc.27012
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http://dx.doi.org/10.1002/pbc.27012DOI Listing
June 2018

Paratesticular alveolar rhabdomyosarcomas do not harbor typical translocations: a distinct entity with favorable prognosis?

Virchows Arch 2018 Mar 21;472(3):441-449. Epub 2018 Feb 21.

Pediatrics 5 (Oncology, Hematology, Immunology), Stuttgart Cancer Center, Klinikum Stuttgart-Olgahospital, Stuttgart, Germany.

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http://dx.doi.org/10.1007/s00428-018-2311-7DOI Listing
March 2018

Enlarging tumor of the lateral chest wall in a 14-year-old boy.

J Dtsch Dermatol Ges 2018 May 29;16(5):640-643. Epub 2018 Jan 29.

Department of Dermatology, Venereology and Allergology, University Medical Center Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1111/ddg.13428DOI Listing
May 2018

Systemic therapy of aggressive fibromatosis in children and adolescents: Report of the Cooperative Weichteilsarkom Studiengruppe (CWS).

Pediatr Blood Cancer 2018 05 5;65(5):e26943. Epub 2018 Jan 5.

Stuttgart Cancer Center, Zentrum für Kinder-, Jugend- und Frauenmedizin, Pediatrics 5 (Oncology, Hematology, and Immunology), Klinikum Stuttgart-Olgahospital, Stuttgart, Germany.

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http://dx.doi.org/10.1002/pbc.26943DOI Listing
May 2018

ETV6-NTRK3 in congenital mesoblastic nephroma: A report of the SIOP/GPOH nephroblastoma study.

Pediatr Blood Cancer 2018 Apr 29;65(4). Epub 2017 Dec 29.

Kiel Pediatric Tumor Registry, Department of Pediatric Pathology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://doi.wiley.com/10.1002/pbc.26925
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http://dx.doi.org/10.1002/pbc.26925DOI Listing
April 2018

Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.

Eur J Hum Genet 2018 01 11;26(1):137-142. Epub 2017 Dec 11.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Duesseldorf, Germany.

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http://dx.doi.org/10.1038/s41431-017-0048-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839031PMC
January 2018

Strong Expression and Amplification of IGF1R in Pleuropulmonary Blastomas.

Pediatr Dev Pathol 2017 Nov-Dec;20(6):475-481. Epub 2017 Apr 6.

1 Department of Pediatric Pathology, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1177/1093526617700945DOI Listing
May 2019

The impact of local control in the treatment of type II/III pleuropulmonary blastoma. Experience of the Cooperative Weichteilsarkom Studiengruppe (CWS).

J Surg Oncol 2017 Feb 19;115(2):164-172. Epub 2017 Jan 19.

Klinikum Stuttgart, Zentrum für Kinder-, Jugend- und Frauenmedizin, Olgahospital, Pediatrics 5 (Pediatric Oncology, Hematology, Immunology), Stuttgart, Germany.

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http://dx.doi.org/10.1002/jso.24416DOI Listing
February 2017

The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system.

Haematologica 2017 02 29;102(2):346-355. Epub 2016 Sep 29.

Department of General Pediatrics, ALL-BFM Study Group, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany

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http://dx.doi.org/10.3324/haematol.2016.147744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286942PMC
February 2017

Synovial Sarcoma Recurrence in Children and Young Adults.

Ann Surg Oncol 2016 12 8;23(Suppl 5):618-626. Epub 2016 Sep 8.

Pediatrics 5 (Oncology, Hematology, Immunology), Olgahospital, Klinikum Stuttgart, Stuttgart, Germany.

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http://dx.doi.org/10.1245/s10434-016-5535-2DOI Listing
December 2016

Connectivity map identifies HDAC inhibition as a treatment option of high-risk hepatoblastoma.

Cancer Biol Ther 2016 11 16;17(11):1168-1176. Epub 2016 Sep 16.

a Department of Pediatric Surgery, Dr. von Hauner Children's Hospital , Ludwig-Maximilians-University Munich , Munich , Germany.

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http://dx.doi.org/10.1080/15384047.2016.1235664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137489PMC
November 2016

Small cell undifferentiated (SCUD) hepatoblastomas: All malignant rhabdoid tumors?

Genes Chromosomes Cancer 2016 12 29;55(12):925-931. Epub 2016 Jul 29.

Department of Pediatric Pathology, Kiel Pediatric Tumor Registry, Christian-Albrechts-University Kiel, Kiel, Germany.

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http://dx.doi.org/10.1002/gcc.22390DOI Listing
December 2016

Primary Metastatic Synovial Sarcoma: Experience of the CWS Study Group.

Pediatr Blood Cancer 2016 07 22;63(7):1198-206. Epub 2016 Mar 22.

Pediatrics 5, Klinikum Stuttgart, Olgahospital, Stuttgart, Germany.

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http://dx.doi.org/10.1002/pbc.25973DOI Listing
July 2016

Severe Obstruction of the Fetal Right Ventricular Outflow Tract Due to a Primary Teratoma Originating From the Interventricular Septum and Resulting in Neonatal Death.

J Ultrasound Med 2016 Mar;35(3):663-7

Division of Prenatal Medicine, Department of Gynecology and Obstetrics, University Hospital of Schleswig-Holstein, Luebeck, Germany (M.G., D.R.H., J.W.), Department of Pediatric Cardiology, University Hospital of Schleswig-Holstein, Kiel, Germany (U.H.), Division of Prenatal Medicine, Amedes Experts, Hamburg, Germany (M.K.), Kiel Pediatric Tumor Registry, Department of Pediatric Pathology, University of Kiel, Kiel, Germany (C.V.).

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http://dx.doi.org/10.7863/ultra.15.03038DOI Listing
March 2016

Central nervous system acute lymphoblastic leukemia: role of natural killer cells.

Blood 2015 May 20;125(22):3420-31. Epub 2015 Apr 20.

Childhood Leukemia Research Section, Department of Pediatric Oncology and the Cancer Research Center, Edmond and Lily Safra Children Hospital and Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel; Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel;

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http://dx.doi.org/10.1182/blood-2014-08-595108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265786PMC
May 2015

Malignant rhabdoid tumor of the kidney: significantly improved response to pre-operative treatment intensified with doxorubicin.

Cancer Genet 2014 Sep 18;207(9):434-6. Epub 2014 Jul 18.

Saarland University Hospital, Pediatric Hematology and Oncology, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.cancergen.2014.07.001DOI Listing
September 2014

1q gain is a frequent finding in preoperatively treated Wilms tumors, but of limited prognostic value for risk stratification in the SIOP2001/GPOH trial.

Genes Chromosomes Cancer 2014 Nov 18;53(11):960-2. Epub 2014 Jul 18.

Kiel Paediatric Tumor Registry, Department of Paediatric Pathology, University of Kiel, Germany.

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http://dx.doi.org/10.1002/gcc.22203DOI Listing
November 2014

Malignant ectomesenchymoma in children and adolescents: report from the Cooperative Weichteilsarkom Studiengruppe (CWS).

Pediatr Blood Cancer 2013 Feb 25;60(2):224-9. Epub 2012 Apr 25.

Olgahospital, Pediatrics 5 (Oncology, Hematology, Immunology, Rheumatology, Gastroenterology and General Pediatrics), Klinikum Stuttgart, Germany.

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http://dx.doi.org/10.1002/pbc.24174DOI Listing
February 2013

Absence of BRAF mutation in pediatric and adolescent germ cell tumors indicate biological differences to adult tumors.

Pediatr Blood Cancer 2012 Oct 6;59(4):732-5. Epub 2011 Dec 6.

Department of Pathology, Hematopathology Section and Lymph Node Registry, University of Kiel, Kiel, Germany.

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http://dx.doi.org/10.1002/pbc.24005DOI Listing
October 2012

Establishment of a rhabdomyosarcoma xenograft model in human-adapted mice.

Oncol Rep 2010 Oct;24(4):1067-72

Department of Pediatric Surgery, University Children's Hospital, 72076 Tübingen, Germany.

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http://dx.doi.org/10.3892/or.2010.1067DOI Listing
October 2010

Effects of standard chemotherapy on tumor growth and regulation of multidrug resistance genes and proteins in childhood rhabdomyosarcoma.

Pediatr Surg Int 2007 May;23(5):431-9

Department of Pediatric Surgery, University Children's Hospital, Hoppe-Seyler-Strasse 1, 72076 Tuebingen, Germany.

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http://dx.doi.org/10.1007/s00383-006-1852-zDOI Listing
May 2007