Christian Trautwein

Christian Trautwein

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Christian Trautwein

Publications by authors named "Christian Trautwein"

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Assessment of liver phenotype in adults with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype).

J Hepatol 2019 Dec 5;71(6):1272-1274. Epub 2019 Oct 5.

Coordinating Center for Alpha-1 Antitrypsin Deficiency-related Liver Disease of the European Reference Network on Hepatological Diseases (ERN RARE-LIVER) and the European Association for the Study of the Liver (EASL) Registry Group "Alpha1-Liver", Germany; Medical Clinic III, Gastroenterology, Metabolic diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.08.011DOI Listing
December 2019

Influence of Liver Fibrosis on Lobular Zonation.

Cells 2019 Dec 2;8(12). Epub 2019 Dec 2.

Leibniz Research Centre for Working Environment and Human Factors at the Technical University Dortmund, 44139 Dortmund, Germany.

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http://dx.doi.org/10.3390/cells8121556DOI Listing
December 2019

Mild Iron Overload as Seen in Individuals Homozygous for the Alpha-1 Antitrypsin Pi*Z Variant Does Not Promote Liver Fibrogenesis in Knockout Mice.

Cells 2019 Nov 9;8(11). Epub 2019 Nov 9.

Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, D-52074 Aachen, Germany.

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http://dx.doi.org/10.3390/cells8111415DOI Listing
November 2019

Fecal Eosinophil Cationic Protein Is a Diagnostic and Predictive Biomarker in Young Adults with Inflammatory Bowel Disease.

J Clin Med 2019 Nov 20;8(12). Epub 2019 Nov 20.

Institute for Internal Medicine III, Clinic for Gastroenterology and Hepatology, University Hospital RWTH Aachen, 52074 Aachen, Germany.

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http://dx.doi.org/10.3390/jcm8122025DOI Listing
November 2019

A Combined Score of Circulating miRNAs Allows Outcome Prediction in Critically Ill Patients.

J Clin Med 2019 Oct 9;8(10). Epub 2019 Oct 9.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.3390/jcm8101644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832199PMC
October 2019

Serum Levels of miR-143 Predict Survival in Critically Ill Patients.

Dis Markers 2019 23;2019:4850472. Epub 2019 Oct 23.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1155/2019/4850472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854254PMC
October 2019

Serum Levels of Kisspeptin Are Elevated in Patients with Pancreatic Cancer.

Dis Markers 2019 20;2019:5603474. Epub 2019 Oct 20.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1155/2019/5603474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6854939PMC
October 2019

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation.

Gastroenterology 2019 09 20;157(3):705-719.e18. Epub 2019 May 20.

Coordinating Center for Alpha1-Antitrypsin Deficiency-Related Liver Disease of the European Reference Network "Rare Liver" and the European Association for the Study of the Liver Registry Group "Alpha1-Liver," University Hospital Aachen, Aachen, Germany; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085194089
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http://dx.doi.org/10.1053/j.gastro.2019.05.013DOI Listing
September 2019

Identifying Efficient Toxin A Binders with a Multivalent Neo-Glycoprotein Glycan Library.

Bioconjug Chem 2019 Sep 9;30(9):2373-2383. Epub 2019 Sep 9.

Laboratory for Biomaterials, Institute for Biotechnology and Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstrasse 20 , 52074 Aachen , Germany.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00486DOI Listing
September 2019

Microgels Sopping Up Toxins-GM1a-Functionalized Microgels as Scavengers for Cholera Toxin.

ACS Appl Mater Interfaces 2019 Jul 2;11(28):25017-25023. Epub 2019 Jul 2.

DWI-Leibniz Institute for Interactive Materials , RWTH Aachen University , Forckenbeckstraße 50 , 52076 Aachen , Germany.

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http://dx.doi.org/10.1021/acsami.9b06413DOI Listing
July 2019

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo.

Biomaterials 2019 Jun 22;206:49-60. Epub 2019 Mar 22.

Department of Medicine III, University Hospital Aachen, Aachen, Germany; Department of Hepatology and Gastroenterology, Charité University Medicine Berlin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.03.025DOI Listing
June 2019

Faecal micro-RNAs in inflammatory bowel diseases.

J Crohns Colitis 2019 Jun 15. Epub 2019 Jun 15.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1093/ecco-jcc/jjz120DOI Listing
June 2019

Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients.

Diagnostics (Basel) 2019 Jun 21;9(2). Epub 2019 Jun 21.

Department of Medicine III, RWTH-University Hospital Aachen, D-52074 Aachen, Germany.

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http://dx.doi.org/10.3390/diagnostics9020063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628070PMC
June 2019

Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure.

Hepatology 2019 May 15;69(5):2136-2149. Epub 2019 Mar 15.

Medical Clinic III, University Hospital Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/hep.30486DOI Listing
May 2019

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence.

Gastroenterology 2019 05 30;156(6):1877-1889.e4. Epub 2019 Jan 30.

Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany; Department of Hepatology/Gastroenterology, Charité University Medical Center, Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193034
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http://dx.doi.org/10.1053/j.gastro.2019.01.247DOI Listing
May 2019

Myeloid cells require gp130 signaling for protective anti-inflammatory functions during sepsis.

FASEB J 2019 May 6;33(5):6035-6044. Epub 2019 Feb 6.

Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.

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http://dx.doi.org/10.1096/fj.201802118RDOI Listing
May 2019

Excellent Response to Anti-PD-1 Therapy in a Patient with Hepatocellular Carcinoma Intolerant to Sorafenib.

Visc Med 2019 Mar 12;35(1):43-46. Epub 2019 Feb 12.

Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1159/000497465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597928PMC
March 2019

CXCR6 protects from inflammation and fibrosis in NEMO mice.

Biochim Biophys Acta Mol Basis Dis 2019 02 24;1865(2):391-402. Epub 2018 Nov 24.

Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09254439183048
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http://dx.doi.org/10.1016/j.bbadis.2018.11.020DOI Listing
February 2019

Heterozygosity for the Alpha-1-Antitrypsin Z Allele in Cirrhosis Is Associated With More Advanced Disease.

Liver Transpl 2019 02;25(2):342-343

Internal Medicine III, University Hospital Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/lt.25393DOI Listing
February 2019

MyD88-dependent signaling in non-parenchymal cells promotes liver carcinogenesis.

Carcinogenesis 2019 Feb 13. Epub 2019 Feb 13.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen Pauwelsstrasse, Germany.

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http://dx.doi.org/10.1093/carcin/bgy173DOI Listing
February 2019

Visfatin Serum Levels Predict Mortality in Critically Ill Patients.

Dis Markers 2018 26;2018:7315356. Epub 2018 Aug 26.

Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1155/2018/7315356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129328PMC
January 2019

Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury.

J Pathol 2019 01 11;247(1):110-122. Epub 2018 Dec 11.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1002/path.5174DOI Listing
January 2019

[Current Developments in Nutritional Therapy of Intensive Care Patients].

Dtsch Med Wochenschr 2018 12 3;143(24):1759-1764. Epub 2018 Dec 3.

Medizinische Klinik III (Gastroenterologie, Stoffwechselerkrankungen und Internistische Intensivmedizin) Universitätsklinikum, RWTH-Aachen.

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http://dx.doi.org/10.1055/a-0647-9417DOI Listing
December 2018

High mobility group box 1 as a biomarker in critically ill patients.

J Clin Lab Anal 2018 Oct 3;32(8):e22584. Epub 2018 Jun 3.

Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany.

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http://doi.wiley.com/10.1002/jcla.22584
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http://dx.doi.org/10.1002/jcla.22584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816880PMC
October 2018

Circulating Levels of Osteopontin Predict Patients' Outcome after Resection of Colorectal Liver Metastases.

J Clin Med 2018 Oct 26;7(11). Epub 2018 Oct 26.

Department of General, Visceral and Transplantation Surgery, University Hospital RWTH Aachen, 52062 Aachen, Germany.

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http://dx.doi.org/10.3390/jcm7110390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262509PMC
October 2018

Liver - master and servant of serum proteome.

J Hepatol 2018 08 28;69(2):512-524. Epub 2018 Apr 28.

Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany; The Interdisciplinary Center for Clinical Research (IZKF), University Hospital Aachen, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.04.018DOI Listing
August 2018

Circulating Biomarkers for Cholangiocarcinoma.

Dig Dis 2018 15;36(4):281-288. Epub 2018 May 15.

Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1159/000488342DOI Listing
August 2018

Growth Differentiation Factor-15 Is a Predictor of Mortality in Critically Ill Patients with Sepsis.

Dis Markers 2017 18;2017:5271203. Epub 2017 Oct 18.

Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://dx.doi.org/10.1155/2017/5271203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664246PMC
July 2018

Loss of Cyclin E1 attenuates hepatitis and hepatocarcinogenesis in a mouse model of chronic liver injury.

Oncogene 2018 06 19;37(25):3329-3339. Epub 2018 Mar 19.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1038/s41388-018-0181-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388396PMC
June 2018

[Management of Clostridium difficile infections at German intensive care units - results from a survey among intensivists].

Z Gastroenterol 2018 06 11;56(6):551-560. Epub 2018 Jun 11.

Klinik für Gastroenterologie, Stoffwechselerkrankungen und Internistische Intensivmedizin, Uniklinik RWTH Aachen.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-102103
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http://dx.doi.org/10.1055/s-0044-102103DOI Listing
June 2018

Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling.

J Hepatol 2018 05 11;68(5):996-1005. Epub 2018 Jan 11.

Department of Internal Medicine III, RWTH University Hospital Aachen, Germany; Interdisciplinary Center for Clinical Research (IZKF), RWTH University Hospital Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.01.003DOI Listing
May 2018

Role of bile acids in the gut-liver axis.

J Hepatol 2018 05 5;68(5):1083-1085. Epub 2018 Mar 5.

Department of Medicine III, University Hospital RWTH Aachen, Germany.

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http://dx.doi.org/10.1016/j.jhep.2017.11.025DOI Listing
May 2018

The Role of miRNAs in the Pathophysiology of Liver Diseases and Toxicity.

Int J Mol Sci 2018 Jan 16;19(1). Epub 2018 Jan 16.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://www.mdpi.com/1422-0067/19/1/261
Publisher Site
http://dx.doi.org/10.3390/ijms19010261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796207PMC
January 2018

miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib.

J Hepatol 2017 11 21;67(5):966-978. Epub 2017 Jun 21.

Department of Medicine III, University of Aachen (RWTH), Pauwelsstraße 30, 52074 Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.06.007DOI Listing
November 2017

Targeting CCl -induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice.

Hepatology 2017 10 26;66(4):1242-1257. Epub 2017 Aug 26.

Department of Internal Medicine III, RWTH Aachen University, Aachen, Germany.

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http://dx.doi.org/10.1002/hep.29275DOI Listing
October 2017

Elevated levels of circulating osteopontin are associated with a poor survival after resection of cholangiocarcinoma.

J Hepatol 2017 10 29;67(4):749-757. Epub 2017 Jun 29.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany; Division of Gastroenterology, Hepatology and Hepatobiliary Oncology, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.06.020DOI Listing
October 2017

Prevalence and nature of potential drug-drug interactions among kidney transplant patients in a German intensive care unit.

Int J Clin Pharm 2017 Oct 19;39(5):1128-1139. Epub 2017 Aug 19.

Hospital Pharmacy, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1007/s11096-017-0525-4DOI Listing
October 2017

Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers.

ACS Nano 2017 10 25;11(10):9689-9700. Epub 2017 Aug 25.

Institute for Organic Chemistry, Johannes Gutenberg-University Mainz , 55122 Mainz, Germany.

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http://dx.doi.org/10.1021/acsnano.7b04630DOI Listing
October 2017

Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame.

Cancers (Basel) 2017 Sep 25;9(10). Epub 2017 Sep 25.

Department of Internal Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, D-52074 Aachen, Germany.

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http://dx.doi.org/10.3390/cancers9100130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664069PMC
September 2017

miR-223 represents a biomarker in acute and chronic liver injury.

Clin Sci (Lond) 2017 Aug 13;131(15):1971-1987. Epub 2017 Jul 13.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany

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http://dx.doi.org/10.1042/CS20170218DOI Listing
August 2017

Current and future biomarkers for pancreatic adenocarcinoma.

Tumour Biol 2017 Jun;39(6):1010428317692231

1 Department of Gastroenterology, Digestive Diseases and Intensive Care Medicine (Department of Medicine III), Division of GI Oncology, University Hospital RWTH Aachen, Aachen, Germany.

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http://dx.doi.org/10.1177/1010428317692231DOI Listing
June 2017

Role of circulating microRNAs in liver diseases.

World J Hepatol 2017 Apr;9(12):586-594

Sven H Loosen, Florian Schueller, Christian Trautwein, Sanchari Roy, Christoph Roderburg, Department of Medicine III, University Hospital RWTH Aachen, 52074 Aachen, Germany.

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http://dx.doi.org/10.4254/wjh.v9.i12.586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411953PMC
April 2017

Reversal of liver fibrosis: From fiction to reality.

Best Pract Res Clin Gastroenterol 2017 Apr 24;31(2):129-141. Epub 2017 Apr 24.

Department of Internal Medicine III, RWTH Aachen University Hospital, Aachen, Germany.

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http://dx.doi.org/10.1016/j.bpg.2017.04.005DOI Listing
April 2017