Publications by authors named "Christian Trautwein"

100Publications

Prolonged Survival of a Patient with Advanced-Stage Combined Hepatocellular-Cholangiocarcinoma.

Case Rep Gastroenterol 2020 Sep-Dec;14(3):658-667. Epub 2020 Dec 10.

Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

View Article and Find Full Text PDF
December 2020

Circulating levels of microRNA193a-5p predict outcome in early stage hepatocellular carcinoma.

PLoS One 2020 22;15(9):e0239386. Epub 2020 Sep 22.

Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

View Article and Find Full Text PDF
November 2020

Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion.

Cell Mol Gastroenterol Hepatol 2020 Sep 4. Epub 2020 Sep 4.

Department of Medicine III, RWTH Aachen University, Aachen, Germany; Department of Hepatology and Gastroenterology, Charité University Medicine Berlin, Berlin, Germany. Electronic address:

View Article and Find Full Text PDF
September 2020

[Diagnostic quality of transluminal biopsy in undetermined biliary duct stenosis by primary PTCD with "cross and push" technique - a prospective monocentric pilot study].

Z Gastroenterol 2020 Oct 22;58(10):939-944. Epub 2020 Jun 22.

Klinik für Innere Medizin und Gastroenterologie, Rhein-Maas Klinikum, Würselen, Germany.

View Article and Find Full Text PDF
October 2020

Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.

Gastroenterology 2020 Oct 17;159(4):1406-1416.e11. Epub 2020 Jun 17.

Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany; Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom; German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany; Medical Oncology, National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

View Article and Find Full Text PDF
October 2020

Between fear and courage: Attitudes, beliefs, and behavior of liver transplantation recipients and waiting list candidates during the COVID-19 pandemic.

Am J Transplant 2020 11 27;20(11):3042-3050. Epub 2020 Jun 27.

Division of Gastroenterology, Hepatology and Infectious Diseases, Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany.

View Article and Find Full Text PDF
November 2020

SARS-CoV-2 as an extrahepatic precipitator of acute-on-chronic liver failure.

Liver Int 2020 07 29;40(7):1792-1793. Epub 2020 May 29.

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

View Article and Find Full Text PDF
July 2020

Pharmacological Inhibition of Cyclin-Dependent Kinases Triggers Anti-Fibrotic Effects in Hepatic Stellate Cells In Vitro.

Int J Mol Sci 2020 May 5;21(9). Epub 2020 May 5.

Department of Internal Medicine III, University Hospital, RWTH Aachen University, D-52074 Aachen, Germany.

View Article and Find Full Text PDF
May 2020

Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?

Int J Mol Sci 2020 Feb 28;21(5). Epub 2020 Feb 28.

MICTLÁN-Network (Mechanisms of Liver Injury, Cell death and translational Nutrition in liver diseases Research Network), Mexico City 14080, Mexico.

View Article and Find Full Text PDF
February 2020

Current status of immunotherapy in gastrointestinal malignancies.

Z Gastroenterol 2020 Jun 4;58(6):542-555. Epub 2020 Feb 4.

Hämatologisch-Onkologische Praxis Eppendorf, University Cancer Center Hamburg, Germany.

View Article and Find Full Text PDF
June 2020

Serum Levels of Kisspeptin Are Elevated in Patients with Pancreatic Cancer.

Dis Markers 2019 20;2019:5603474. Epub 2019 Oct 20.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

View Article and Find Full Text PDF
April 2020

Serum Levels of miR-143 Predict Survival in Critically Ill Patients.

Dis Markers 2019 23;2019:4850472. Epub 2019 Oct 23.

Department of Medicine III, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

View Article and Find Full Text PDF
April 2020

Fecal Eosinophil Cationic Protein Is a Diagnostic and Predictive Biomarker in Young Adults with Inflammatory Bowel Disease.

J Clin Med 2019 Nov 20;8(12). Epub 2019 Nov 20.

Institute for Internal Medicine III, Clinic for Gastroenterology and Hepatology, University Hospital RWTH Aachen, 52074 Aachen, Germany.

View Article and Find Full Text PDF
November 2019

Assessment of liver phenotype in adults with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype).

J Hepatol 2019 12 5;71(6):1272-1274. Epub 2019 Oct 5.

Coordinating Center for Alpha-1 Antitrypsin Deficiency-related Liver Disease of the European Reference Network on Hepatological Diseases (ERN RARE-LIVER) and the European Association for the Study of the Liver (EASL) Registry Group "Alpha1-Liver", Germany; Medical Clinic III, Gastroenterology, Metabolic diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany. Electronic address:

View Article and Find Full Text PDF
December 2019

Identifying Efficient Toxin A Binders with a Multivalent Neo-Glycoprotein Glycan Library.

Bioconjug Chem 2019 09 9;30(9):2373-2383. Epub 2019 Sep 9.

Laboratory for Biomaterials, Institute for Biotechnology and Helmholtz-Institute for Biomedical Engineering , RWTH Aachen University , Pauwelsstrasse 20 , 52074 Aachen , Germany.

View Article and Find Full Text PDF
September 2019

Excellent Response to Anti-PD-1 Therapy in a Patient with Hepatocellular Carcinoma Intolerant to Sorafenib.

Visc Med 2019 Mar 12;35(1):43-46. Epub 2019 Feb 12.

Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

View Article and Find Full Text PDF
March 2019

Microgels Sopping Up Toxins-GM1a-Functionalized Microgels as Scavengers for Cholera Toxin.

ACS Appl Mater Interfaces 2019 Jul 2;11(28):25017-25023. Epub 2019 Jul 2.

DWI-Leibniz Institute for Interactive Materials , RWTH Aachen University , Forckenbeckstraße 50 , 52076 Aachen , Germany.

View Article and Find Full Text PDF
July 2019

Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients.

Diagnostics (Basel) 2019 Jun 21;9(2). Epub 2019 Jun 21.

Department of Medicine III, RWTH-University Hospital Aachen, D-52074 Aachen, Germany.

View Article and Find Full Text PDF
June 2019

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation.

Gastroenterology 2019 09 20;157(3):705-719.e18. Epub 2019 May 20.

Coordinating Center for Alpha1-Antitrypsin Deficiency-Related Liver Disease of the European Reference Network "Rare Liver" and the European Association for the Study of the Liver Registry Group "Alpha1-Liver," University Hospital Aachen, Aachen, Germany; Medical Clinic III, Gastroenterology, Metabolic Diseases and Intensive Care, University Hospital Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany. Electronic address:

View Article and Find Full Text PDF
September 2019

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo.

Biomaterials 2019 06 22;206:49-60. Epub 2019 Mar 22.

Department of Medicine III, University Hospital Aachen, Aachen, Germany; Department of Hepatology and Gastroenterology, Charité University Medicine Berlin, Berlin, Germany. Electronic address:

View Article and Find Full Text PDF
June 2019

MyD88-dependent signaling in non-parenchymal cells promotes liver carcinogenesis.

Carcinogenesis 2020 04;41(2):171-181

Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen Pauwelsstrasse, Germany.

View Article and Find Full Text PDF
April 2020

Myeloid cells require gp130 signaling for protective anti-inflammatory functions during sepsis.

FASEB J 2019 05 6;33(5):6035-6044. Epub 2019 Feb 6.

Department of Internal Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany.

View Article and Find Full Text PDF
May 2019

CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4 T-Cell-Dependent Control of Senescence.

Gastroenterology 2019 05 30;156(6):1877-1889.e4. Epub 2019 Jan 30.

Department of Medicine III, RWTH-University Hospital Aachen, Aachen, Germany; Department of Hepatology/Gastroenterology, Charité University Medical Center, Berlin, Germany. Electronic address:

View Article and Find Full Text PDF
May 2019

[Current Developments in Nutritional Therapy of Intensive Care Patients].

Dtsch Med Wochenschr 2018 12 3;143(24):1759-1764. Epub 2018 Dec 3.

Medizinische Klinik III (Gastroenterologie, Stoffwechselerkrankungen und Internistische Intensivmedizin) Universitätsklinikum, RWTH-Aachen.

View Article and Find Full Text PDF
December 2018

CXCR6 protects from inflammation and fibrosis in NEMO mice.

Biochim Biophys Acta Mol Basis Dis 2019 02 24;1865(2):391-402. Epub 2018 Nov 24.

Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address:

View Article and Find Full Text PDF
February 2019

Circulating Levels of Osteopontin Predict Patients' Outcome after Resection of Colorectal Liver Metastases.

J Clin Med 2018 Oct 26;7(11). Epub 2018 Oct 26.

Department of General, Visceral and Transplantation Surgery, University Hospital RWTH Aachen, 52062 Aachen, Germany.

View Article and Find Full Text PDF
October 2018

Visfatin Serum Levels Predict Mortality in Critically Ill Patients.

Dis Markers 2018 26;2018:7315356. Epub 2018 Aug 26.

Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.

View Article and Find Full Text PDF
January 2019

A General Overview on Non-coding RNA-Based Diagnostic and Therapeutic Approaches for Liver Diseases.

Front Pharmacol 2018 15;9:805. Epub 2018 Aug 15.

Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

View Article and Find Full Text PDF
August 2018