Christian Trepo

Christian Trepo

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Christian Trepo

Publications by authors named "Christian Trepo"

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Non-F HBV/HDV-3 coinfection is associated with severe liver disease in Western Brazilian Amazon.

J Med Virol 2019 Jun 11;91(6):1081-1086. Epub 2019 Feb 11.

Institut National de la Santé et de la Recherche Medicale, INSERM U1052, Lyon, France.

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http://doi.wiley.com/10.1002/jmv.25411
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http://dx.doi.org/10.1002/jmv.25411DOI Listing
June 2019

Anti-E1E2 antibodies status prior therapy favors direct-acting antiviral treatment efficacy.

Clin Res Hepatol Gastroenterol 2018 09 16;42(4):313-318. Epub 2018 Mar 16.

Centre de recherche en cancérologie de Lyon (CRCL), UMR Inserm 1052/CNRS 5286, 69003 Lyon, France; Université Claude-Bernard-Lyon 1, 69008 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2018.02.002DOI Listing
September 2018

Efficiency and Safety of an Early Dose Adjustment of Ribavirin in Patients Infected With Hepatitis C Underexposed to the Drug and Treated With Peginterferon Ribavirin.

Ther Drug Monit 2016 12;38(6):684-692

*Service d'Hépatogastroentérologie, Hôpital Dupuytren, Limoges; †INSERM, U850, Université de Limoges, F-87000 Limoges; ‡Service d'Hépatologie, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon; §INSERM, U1092, Université de Limoges, F-87000 Limoges; ∥Laboratoire de Pharmacologie Spécialisée, Hôpital E. Herriot, Hospices Civils de Lyon, Lyon; ¶U1052, INSERM, Lyon; **Pôle de Référence Hépatite C, Hôpital Archet 2, Nice; ††Service d'Hépato-gastro-entérologie et nutrition, Hôpital de la Côte de Nacre, CAEN; ‡‡Service d'Hépato-gastro-entérologie, Centre Hospitalier Universitaire de Poitiers; §§Département Biologie des agents infectieux et pharmacotoxicologie-Virologie, Centre Hospitalier Universitaire d'Angers, Angers; ‖‖Direction de la Recherche Clinique et de l'Innovation, Hospices Civils de Lyon, Lyon, France; and ¶¶Laboratoire de Pharmacologie Médicale, Université de Limoges.

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http://dx.doi.org/10.1097/FTD.0000000000000332DOI Listing
December 2016

Anti-E1E2 antibodies do predict response to triple therapy in treatment-experienced Hepatitis C Virus-cirrhosis cases.

Clin Res Hepatol Gastroenterol 2015 Dec 18;39(6):699-704. Epub 2015 Apr 18.

Centre de recherche en cancérologie de Lyon (CRCL), UMR I 1052/CNRS 5286, 69424 Lyon cedex 03, France; Université Claude-Bernard Lyon 1, 69100 Villeurbanne, France; Hospices civils de Lyon, hôpital de la Croix-Rousse, service d'hépatologie et de gastroentérologie, 69004 Lyon, France.

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http://dx.doi.org/10.1016/j.clinre.2015.03.002DOI Listing
December 2015

Hepatitis: After HCV cure, HBV cure?

Nat Rev Gastroenterol Hepatol 2015 Jul 23;12(7):376-8. Epub 2015 Jun 23.

INSERM U1052, CNRS UMR_5286, Cancer Research Center of Lyon (CRCL), 151 Cours Albert Thomas, 69424 Lyon Cedex 03, France.

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http://dx.doi.org/10.1038/nrgastro.2015.103DOI Listing
July 2015

Hepatitis B virus infection.

Lancet 2014 Dec 18;384(9959):2053-63. Epub 2014 Jun 18.

Division of Gastroenterology and Hepatology, University of Michigan Health System, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/S0140-6736(14)60220-8DOI Listing
December 2014

Pretreatment predictive factors for hepatitis C therapy outcome: relevance of anti-E1E2 antibodies compared to IP-10 and IL28B genotypes.

Antivir Ther 2013 15;18(8):1027-32. Epub 2013 Aug 15.

Centre de Recherche en Cancérologie de Lyon (CRCL), INSERM U1052/CNRS UMR5286, Lyon, France.

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http://dx.doi.org/10.3851/IMP2671DOI Listing
October 2014

Occult HBV infection in Morocco: from chronic hepatitis to hepatocellular carcinoma.

Liver Int 2014 Jul 11;34(6):e144-50. Epub 2014 Mar 11.

Viral Hepatitis Laboratory, Pasteur Institute of Morocco, Casablanca, Morocco.

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http://dx.doi.org/10.1111/liv.12482DOI Listing
July 2014

Diversity of hepatocellular carcinoma clones bearing hematopoietic malignancies-related chromosomal translocation.

J Cell Biochem 2014 Apr;115(4):666-77

DevWeCan Laboratories of Excellence Network (Labex), Université de Lyon, Lyon Cancer Research Center, Inserm U1052-CNRS UMR5286, Lyon, France.

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http://dx.doi.org/10.1002/jcb.24706DOI Listing
April 2014

Predictors of the therapeutic response in hepatitis C. A 2013 update.

Clin Res Hepatol Gastroenterol 2014 Feb 21;38(1):12-7. Epub 2013 Nov 21.

Inserm U1052/CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon (CRCL), 151, Cours-Albert-Thomas, 69424 Lyon cedex 03, France; Université Claude-Bernard Lyon 1, 69000 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.clinre.2013.08.003DOI Listing
February 2014

A brief history of hepatitis milestones.

Authors:
Christian Trepo

Liver Int 2014 Feb;34 Suppl 1:29-37

Hepatology Unit, CROIX ROUSSE Hospital and INSERM U1052, Lyon, France.

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http://dx.doi.org/10.1111/liv.12409DOI Listing
February 2014

Discovery of naturally occurring transmissible chronic hepatitis B virus infection among Macaca fascicularis from Mauritius Island.

Hepatology 2013 Nov 17;58(5):1610-20. Epub 2013 Sep 17.

Université de Lyon, Lyon, France; INSERM U1052, Centre de Recherche en Cancérologie de Lyon, Lyon, France; CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, Lyon, France; Ecole pratique des hautes études, Paris, France.

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http://dx.doi.org/10.1002/hep.26428DOI Listing
November 2013

Improved rolling circle amplification (RCA) of hepatitis B virus (HBV) relaxed-circular serum DNA (RC-DNA).

J Virol Methods 2013 Nov 5;193(2):653-9. Epub 2013 Aug 5.

Centre de Recherche en Cancérologie de Lyon (CRCL); INSERM, U1052; CNRS, UMR 5286; UCBL1, S_1052. 151 cours Albert Thomas, 69003 Lyon, France.

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http://dx.doi.org/10.1016/j.jviromet.2013.07.045DOI Listing
November 2013

Farnesoid X receptor targeting for hepatitis C: study protocol for a proof-of-concept trial.

Therapie 2012 Sep-Oct;67(5):423-7. Epub 2012 Dec 18.

Hospices Civils de Lyon, Hôpital de la Croix Rousse, Laboratory of Virology, Lyon, France.

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http://dx.doi.org/10.2515/therapie/2012058DOI Listing
April 2013

Probable corticosteroid-induced reactivation of latent hepatitis B virus infection in an HIV-positive patient involving immune escape.

J Infect Dis 2012 Jun 29;205(11):1757-61. Epub 2012 Mar 29.

Centre de Recherche en Cancérologie de Lyon, Hôpital de la Croix-Rousse, Lyon, France.

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http://dx.doi.org/10.1093/infdis/jis268DOI Listing
June 2012

Long-term propagation of serum hepatitis C virus (HCV) with production of enveloped HCV particles in human HepaRG hepatocytes.

Hepatology 2011 Aug 30;54(2):406-17. Epub 2011 Jun 30.

Centre de Recherche en Cancérologie de Lyon (CRCL), INSERM U1052/CNRS UMR5286, Université Claude Bernard Lyon 1, and Hospices Civils de Lyon, Hôpital de la Croix Rousse, Service d'Hépatologie et de Gastroentérologie, Lyon, France.

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http://dx.doi.org/10.1002/hep.24386DOI Listing
August 2011

Evolution of Hepatitis B and C serum markers: a still challenging issue.

Liver Int 2011 Aug 16;31(7):905-7. Epub 2011 Mar 16.

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http://dx.doi.org/10.1111/j.1478-3231.2011.02479.xDOI Listing
August 2011

Prevalence and challenges of liver diseases in patients with chronic hepatitis C virus infection.

Clin Gastroenterol Hepatol 2010 Nov 14;8(11):924-33; quiz e117. Epub 2010 Aug 14.

Division of Gastroenterology and Hepatology and Center for Study of Hepatitis C, Joan and Sanford I. Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.cgh.2010.06.032DOI Listing
November 2010

Association of anti-E1E2 antibodies with spontaneous recovery or sustained viral response to therapy in patients infected with hepatitis C virus.

Hepatology 2010 Nov;52(5):1531-42

Institut National de la Santé et de la Recherche Médicale (INSERM), Unit 871, Molecular Physiopathology and New Therapies in Viral Hepatitis, Lyon, France.

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http://doi.wiley.com/10.1002/hep.23862
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http://dx.doi.org/10.1002/hep.23862DOI Listing
November 2010

Sarcoidosis and hepatitis C: clinical description of 11 cases.

Eur J Gastroenterol Hepatol 2010 Aug;22(8):967-72

Department of Internal Medicine, Université Claude Bernard Lyon, 1 place de l'Hôpital, Lyon Cedex, France.

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http://dx.doi.org/10.1097/MEG.0b013e32833834bcDOI Listing
August 2010

Maintenance ribavirin monotherapy: the case for post-transplantation recurrent hepatitis C.

Dig Liver Dis 2010 Apr 26;42(4):283-4. Epub 2010 Feb 26.

Department of Hepatogastroenterology, Hospices Civils de Lyon Hopital Hotel Dieu, 69002 Lyon, France.

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http://linkinghub.elsevier.com/retrieve/pii/S159086581000046
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http://dx.doi.org/10.1016/j.dld.2010.02.001DOI Listing
April 2010

Management of nonresponsive hepatitis C.

Expert Rev Anti Infect Ther 2010 Apr;8(4):379-95

INSERM, U871, Lyon, France.

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http://dx.doi.org/10.1586/eri.10.17DOI Listing
April 2010

Molecular mechanisms underlying hepatocellular carcinoma.

Viruses 2009 12 9;1(3):852-72. Epub 2009 Nov 9.

INSERM, U871, 69003 Lyon; Université Lyon 1, IFR62 Lyon-Est, 69008 Lyon, France.

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http://www.mdpi.com/1999-4915/1/3/852
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http://dx.doi.org/10.3390/v1030852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185529PMC
December 2009

Inhibition of the binding of HCV serum particles to human hepatocytes by E1E2-specific D32.10 monoclonal antibody.

J Med Virol 2009 Oct;81(10):1726-33

Institut National de la Santé et de la Recherche Médicale, U871, Lyon, France.

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http://dx.doi.org/10.1002/jmv.21562DOI Listing
October 2009

Hepatitis C: CIFN for re-treatment of PEG-IFN plus RBV nonresponders?

Nat Rev Gastroenterol Hepatol 2009 Oct;6(10):570-1

Department of Hepatogastroenterology Hôtel Dieu Hospital University, Claude Bernard Lyon 1, and Hepatitis INSERM Unit U871, Lyon, France.

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http://www.nature.com/articles/nrgastro.2009.145
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http://dx.doi.org/10.1038/nrgastro.2009.145DOI Listing
October 2009

Severe autoimmune cytopenias in treatment-naive hepatitis C virus infection: clinical description of 16 cases.

Eur J Gastroenterol Hepatol 2009 Mar;21(3):245-53

Department of Internal Medicine, University Claude Bernard, Lyon 1, Lyon, France.

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http://dx.doi.org/10.1097/MEG.0b013e3283249908DOI Listing
March 2009

Occult hepatitis B virus infection in HIV-infected patients: Evaluation of biochemical, virological and molecular parameters.

Hepatol Res 2008 Dec 24;38(12):1194-203. Epub 2008 Jun 24.

Laboratory of Molecular Virology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1111/j.1872-034X.2008.00392.xDOI Listing
December 2008

Prediction of sustained virological response by ribavirin plasma concentration at week 4 of therapy in hepatitis C virus genotype 1 patients.

Antivir Ther 2008 ;13(4):607-11

Hospices Civils de Lyon, Hôtel Dieu, Service d'hépatologie et de gastroentérologie, 69002 Lyon, France.

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September 2008

Occult B infection in the Brazilian northeastern region: a preliminary report.

Braz J Infect Dis 2008 Aug;12(4):310-2

Medical School of Bahia, Post-graduation course in Health and Medicine, Salvador, Bahia, Brazil.

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August 2008

Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure.

J Hepatol 2008 May 25;48(5):747-55. Epub 2008 Feb 25.

INSERM U871, Laboratoire des virus hépatiques et pathologies associées, 151 cours Albert Thomas, Lyon cedex 03, France.

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http://dx.doi.org/10.1016/j.jhep.2008.01.027DOI Listing
May 2008

Genotype determination in Moroccan hepatitis B chronic carriers.

Infect Genet Evol 2008 May 3;8(3):306-12. Epub 2008 Feb 3.

Institut Pasteur du Maroc 1, Place Louis Pasteur, 20100 Casablanca, Maroc, Morocco.

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http://dx.doi.org/10.1016/j.meegid.2008.01.010DOI Listing
May 2008

Characterization of the double-stranded RNA responses in human liver progenitor cells.

Biochem Biophys Res Commun 2008 Apr 5;368(3):556-62. Epub 2008 Feb 5.

INSERM, U871, 69003 Lyon, France.

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http://dx.doi.org/10.1016/j.bbrc.2008.01.123DOI Listing
April 2008

[Maintenance therapy for chronic hepatitis C].

Gastroenterol Clin Biol 2007 Aug-Sep;31(8-9 Pt 3):4S29-33

Service d'Hépato-Gastro-entérologie, Hôpital de l'Hôtel-Dieu & Unité INSERM U871, 1 place de l'Hôpital, 69288 Lyon cedex 02.

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January 2008

Interferon-based treatment of chronic hepatitis C.

Biochimie 2007 Jun-Jul;89(6-7):894-8. Epub 2007 May 8.

Hospices Civils de Lyon, Hôtel Dieu, Service d'Hépatologie et Gastroentérologie, 69002 Lyon, France.

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http://dx.doi.org/10.1016/j.biochi.2007.04.017DOI Listing
September 2007

Progression to cirrhosis in hepatitis C patients: an age-dependent process.

Liver Int 2007 Apr;27(3):335-9

Department of Hepatogastroenterology, Hôtel-Dieu, Lyon, France.

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http://dx.doi.org/10.1111/j.1478-3231.2006.01430.xDOI Listing
April 2007

Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.

J Hepatol 2007 Mar 18;46(3):531-8. Epub 2006 Dec 18.

INSERM, U271, Laboratoire des virus hépatiques et pathologies associées, Lyon F-69003, France.

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http://dx.doi.org/10.1016/j.jhep.2006.11.016DOI Listing
March 2007

Satisfaction of patients treated for chronic hepatitis C with the peginterferon alfa-2b pen device: the VISA observational study.

Gastroenterol Clin Biol 2007 Feb;31(2):180-4

Centre Hospitalier Laënnec, Service d'Hépato-Gastroentérologie et de Diabétologie, Boulevard Laënnec, BP 72, 60109 Creil.

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February 2007

Hypertensive crisis, hepatitis B virus and polyarteritis nodosa in a child.

Pediatr Nephrol 2007 Jan 15;22(1):97-100. Epub 2006 Nov 15.

Néphrologie Pédiatrique, Hôpital Edouard Herriot, Lyon, France.

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http://link.springer.com/10.1007/s00467-006-0222-3
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http://dx.doi.org/10.1007/s00467-006-0222-3DOI Listing
January 2007

Anti-Golgi complex antibodies during pegylated-interferon therapy for hepatitis C.

Liver Int 2006 Nov;26(9):1148-54

Gastro-Hepatology Unit, Faculty of Medicine, University Hospital of Bahia, Bahia, Brazil.

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http://dx.doi.org/10.1111/j.1478-3231.2006.01345.xDOI Listing
November 2006

Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.

Gastroenterology 2006 Oct 16;131(4):1253-61. Epub 2006 Aug 16.

INSERM U271, Laboratoire des Virus Hépatiques et Pathologies Associées, 151 cours Albert Thomas, 69424 Lyon cedex 03, France.

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http://dx.doi.org/10.1053/j.gastro.2006.08.013DOI Listing
October 2006

HDV genotypes in the Western Brazilian Amazon region: A preliminary report.

Am J Trop Med Hyg 2006 Sep;75(3):475-9

Gonçalo Moniz Research Center, Salvador, Brazil; INSERM Unit 271, Université Claude Bernard Lyon 1, IFR 62, Lyon, France.

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September 2006

Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes.

J Hepatol 2006 May 2;44(5):842-7. Epub 2005 Nov 2.

INSERM Unit 271, 151 cours Albert Thomas, 69003 Lyon, France.

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http://dx.doi.org/10.1016/j.jhep.2005.09.014DOI Listing
May 2006

Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.

J Gen Virol 2006 Apr;87(Pt 4):861-71

INSERM U271, Laboratoire des Virus Hépatiques et Pathologies Associées, 151 cours Albert Thomas, 69424 Lyon Cedex 03, France.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.81503-0DOI Listing
April 2006

Amantadine triple therapy for non-responder hepatitis C patients. Clues for controversies (ANRS HC 03 BITRI).

J Hepatol 2006 Mar 20;44(3):484-90. Epub 2005 Dec 20.

Department of Hepato-gastroenterology, Hôtel-Dieu, 1 place de l'Hôpital, 69288 Lyon Cedex 02, France.

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http://dx.doi.org/10.1016/j.jhep.2005.11.038DOI Listing
March 2006

What is really ongoing during occult HBV reactivation?

Hepatology 2006 Jan;43(1):195; author reply 195-6

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http://dx.doi.org/10.1002/hep.21008DOI Listing
January 2006

Resistance of human hepatitis B virus to reverse transcriptase inhibitors: from genotypic to phenotypic testing.

J Clin Virol 2005 Dec;34 Suppl 1:S34-43

INSERM Unit 271, 151 Cours Albert Thomas, 69424 Lyon Cedex 03, France

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December 2005

Oncogenic role of the frizzled-7/beta-catenin pathway in hepatocellular carcinoma.

J Hepatol 2005 Nov 21;43(5):854-62. Epub 2005 Jun 21.

Department of Medicine and Pathology, Brown Medical School, The Liver Research Center, Providence, 55 Claverick St., 4th Floor, Providence, RI 02903, Rhode Island 02903, USA.

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http://dx.doi.org/10.1016/j.jhep.2005.05.018DOI Listing
November 2005

Liver histological alterations in patients with chronic hepatitis C and normal ALT levels in the city of Salvador, Northeast-Brazil.

Braz J Infect Dis 2005 Apr 18;9(2):134-41. Epub 2005 Aug 18.

Gastro-Hepatology Service Hospital Prof. Edgard Santos, Federal University of Bahia, Salvador, Brazil.

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http://dx.doi.org//S1413-86702005000200003DOI Listing
April 2005