Christian Thiede

Christian Thiede

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Christian Thiede

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Clinical Challenges and Consequences of Measurable Residual Disease in Non-APL Acute Myeloid Leukemia.

Cancers (Basel) 2019 Oct 23;11(11). Epub 2019 Oct 23.

Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, Leipzig University Hospital, 04103 Leipzig, Germany.

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http://dx.doi.org/10.3390/cancers11111625DOI Listing
October 2019

Evaluation of TERT promoter mutations in urinary cell-free DNA and sediment DNA for detection of bladder cancer.

Clin Biochem 2019 Feb 4;64:60-63. Epub 2018 Dec 4.

Department of Urology, University Hospital and Faculty of Medicine, Technische Universität Dresden, Dresden, Germany; National Center for Tumor Diseases (NCT), Partner site Dresden, Dresden, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00099120183094
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http://dx.doi.org/10.1016/j.clinbiochem.2018.11.009DOI Listing
February 2019

Characterization of acute myeloid leukemia with del(9q) - Impact of the genes in the minimally deleted region.

Leuk Res 2019 01 17;76:15-23. Epub 2018 Nov 17.

Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen University, Aachen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.11.007DOI Listing
January 2019

Radiographic assessment of contrast enhancement and T2/FLAIR mismatch sign in lower grade gliomas: correlation with molecular groups.

J Neurooncol 2019 Jan 7;141(2):327-335. Epub 2018 Dec 7.

Translational Neuro-Oncology Laboratory, Department of Neurosurgery, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s11060-018-03034-6DOI Listing
January 2019

Validation of the Revised Pretransplant Assessment of Mortality Score in Patients with Acute Myelogenous Leukemia Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2018 09 21;24(9):1947-1951. Epub 2018 May 21.

Universitätsklinikum Carl Gustav Carus der TU Dresden, Medizinische Klinik und Poliklinik I, Dresden, Germany; Deutsche Knochenmarkspenderdatei Clinical Trials Unit, Dresden, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2018.05.021DOI Listing
September 2018

Germ line predisposition to myeloid malignancies appearing in adulthood.

Expert Rev Hematol 2018 08 23;11(8):625-636. Epub 2018 Jul 23.

a Medical Faculty, Dept. of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation , University Hospital RWTH Aachen , Aachen , Germany.

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http://dx.doi.org/10.1080/17474086.2018.1494566DOI Listing
August 2018

Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas.

J Neurosurg 2017 08 25;127(2):438-444. Epub 2016 Nov 25.

Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.3171/2016.8.JNS161076DOI Listing
August 2017

Lipidomic approach for stratification of acute myeloid leukemia patients.

PLoS One 2017 16;12(2):e0168781. Epub 2017 Feb 16.

Paul Langerhans Institute Dresden of the Helmholtz Centre Munich at the University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168781PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313223PMC
August 2017

Dynamics of epigenetic age following hematopoietic stem cell transplantation.

Haematologica 2017 08 26;102(8):e321-e323. Epub 2017 May 26.

Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Germany.

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http://dx.doi.org/10.3324/haematol.2016.160481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541887PMC
August 2017

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation.

N Engl J Med 2017 08 23;377(5):454-464. Epub 2017 Jun 23.

From the Department of Medical Oncology, Dana-Farber Cancer Institute, Boston (R.M.S.); the Division of Biomedical Statistics and Informatics (S.J.M., K.L.) and the Alliance Statistics and Data Center (S.J.M., K.L., S.G.), Mayo Clinic, Rochester, MN; the Alliance Statistics and Data Center, Duke University, Durham, NC (B.L.S.); the Ohio State University Comprehensive Cancer Center, Columbus (S.G., C.D.B., T.W.P., G.M., R.B.K.); Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden (C.T., G.E.), Department of Internal Medicine III, University Hospital of Ulm, Ulm (K.D., R.F.S., H.D.), Hematology and Oncology, University of Leipzig, Leipzig (D.N.), Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover (J.K., A.G.), and Department of Medicine II, Hematology-Oncology, Goethe University Hospital Frankfurt, Frankfurt am Main (H.S.) - all in Germany; the Department of Biomedicine and Prevention, University Tor Vergata, Rome (F.L.-C., S.A.); the Department of Clinical Haematology, Alfred Hospital and Monash University, Melbourne, VIC, Australia (A.W.); Hospital de la Santa Creu i Sant Pau, Hematology Department, Autonomous University of Barcelona, Barcelona (J.S.), and Hospital Universitario la Fe, Hematology Department, Department of Medicine, University of Valencia, Valencia (M.A.S.) - both in Spain; the Department of Medical Oncology and Hematology, Princess Margaret Hospital, Toronto (J.M.B.); Radboud Institute Molecular Studies, Radboud University Medical Center, Nijmegen, the Netherlands (T.W.); the Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle (F.R.A.); the Division of Hematology-Oncology, Stanford Comprehensive Cancer Center, Stanford University, Stanford, CA (B.C.M.); the Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York (M.S.T.); and the Department of Medicine, University of Chicago, Chicago (R.A.L.).

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http://dx.doi.org/10.1056/NEJMoa1614359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754190PMC
August 2017

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial.

J Clin Oncol 2017 Feb 31;35(6):605-612. Epub 2016 Oct 31.

Uwe Platzbecker, Christian Thiede, Christoph Röllig, and Gerhard Ehninger, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden; Uwe Platzbecker and Gerhard Ehninger, Study Alliance Leukemia, Dresden; Walter Fiedler, University Hospital Hamburg-Eppendorf; Norbert Schmitz, Asklepios Klinik St Georg Hamburg, Hamburg; Peter Brossart, Innere Medizin mit deSchwerpunkten Onkologie, Haematollogie un Rheumatologie, Bonn; Bernd Hertenstein, Klinikum Bremen Mitte, Bremen; Helmut R. Salih, University Hospital Tubingen; Mohammed Wattad, Kliniken Essen Süd, Essen; Michael Lübbert, University Medical Center, Freiburg; Christian H. Brandts, Goethe University Frankfurt, Frankfurt; Mathias Hänel, Klinikum Chemnitz gGmbH, Chemnitz; Hartmut Link, Klinik für Innere Medizin I, Westpfalz-Klinikum, Kaiserslautern; Konstanze Döhner, Hartmut Döhner, and Richard F. Schlenk, University Hospital Ulm, Ulm; Arnold Ganser, Hannover Medical School, Hannover, Germany; Giuseppe Avvisati, University Campus Bio-Medico; Laura Cicconi, Mariadomenica Divona, Sergio Amadori, and Francesco Lo-Coco, University Tor Vergata; Francesca Paoloni, Marco Vignetti, Fabio Efficace, Paola Fazi, and Franco Mandelli, Gruppo Italiano Malattie Ematologiche dell'Adulto Central Office; Marco Vignetti and Massimo Breccia, Sapienza University, Rome; Felicetto Ferrara, Cardarelli Hospital, Naples; Francesco Albano, University of Bari, Bari; Marco Sborgia, U.O. di Ematologia Clinica, Pescara; Eros Di Bona, San Bortolo Hospital, Vicenza; Erika Borlenghi, U.O. di Ematologia, Spedali Civili, Brescia; Roberto Cairoli, Ospedale Niguarda, Ca' Granda, SC Ematologia; Agostino Cortelezzi, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico and University of Milan, Milano; Alessandro Rambaldi, Azienda Opsedaliera Papa Giovanni XXIII, Bergamo; Lorella Melillo, Casa Sollievo della Sofferenza Hospital, IRCCS, San Giovanni Rotondo; Giorgio La Nasa, Centro Trapianti Midollo Osseo, Ospedale R. Binaghi, Università di Cagliari, Cagliari; Chiara Frairia, Hematology, Città della Salute e della Scienza, Torino; Enrico Maria Pogliani, Ospedale San Gerardo, Università degli Studi Milano Bicocca, Monza; Claudio Fozza, University of Sassari, Sassari; Alfonso Maria D'Arco, U.O. Medicina Interna e Onco-Ematologica P.O. "Umberto I," Nocera Inferiore, Nocera Inferiore; Nicola Di Renzo, Ospedale Vito Fazzi, Lecce; and Francesco Fabbiano, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.

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http://dx.doi.org/10.1200/JCO.2016.67.1982DOI Listing
February 2017

Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy.

Haematologica 2017 02 17;102(2):e39-e42. Epub 2016 Nov 17.

Faculty of Medicine Carl Gustav Carus, Institute for Medical Informatics and Biometry, Technische Universität Dresden, Mannheim, Germany

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http://dx.doi.org/10.3324/haematol.2016.154138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286951PMC
February 2017

Inactivation of Cancer Mutations Utilizing CRISPR/Cas9.

J Natl Cancer Inst 2017 01 30;109(1). Epub 2016 Aug 30.

Affiliations of author: Medical Systems Biology, Medical Faculty Carl Gustav Carus, University cancer center, Technische Universitat Dresden, Dresden, Germany.

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http://dx.doi.org/10.1093/jnci/djw183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284257PMC
January 2017

Evolution of a FLT3-TKD mutated subclone at meningeal relapse in acute promyelocytic leukemia.

Cold Spring Harb Mol Case Stud 2016 Sep;2(5):a001123

Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany;; Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany;

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http://dx.doi.org/10.1101/mcs.a001123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002926PMC
September 2016

Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia.

Oncotarget 2015 Nov;6(36):38804-15

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universität, Dresden, Germany.

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http://dx.doi.org/10.18632/oncotarget.5661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770738PMC
November 2015

MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML.

Exp Hematol 2015 Sep 11;43(9):794-802.e4. Epub 2015 Jun 11.

Department of Medicine A, Hematology, Hemostaseology, Oncology and Pneumology, University of Muenster, Muenster, Germany; Department of Medicine, Hematology and Oncology, University of Halle, Halle, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2015.05.010DOI Listing
September 2015

Can prognostic scoring systems for chronic myeloid leukemia as established in adults be applied to pediatric patients?

Ann Hematol 2015 Aug 19;94(8):1363-71. Epub 2015 Apr 19.

Pediatric Hematology and Oncology, Department of Pediatrics, University Hospital "Carl Gustav Carus", Technical University Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.

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http://dx.doi.org/10.1007/s00277-015-2367-2DOI Listing
August 2015

Optimizing the performance of bandpass photon detectors for inverse photoemission: Transmission of alkaline earth fluoride window crystals.

Rev Sci Instrum 2015 Aug;86(8):085101

Physikalisches Institut, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Straße 10, 48149 Münster, Germany.

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http://dx.doi.org/10.1063/1.4927459DOI Listing
August 2015

Allogeneic stem-cell transplantation in patients with NPM1-mutated acute myeloid leukemia: results from a prospective donor versus no-donor analysis of patients after upfront HLA typing within the SAL-AML 2003 trial.

J Clin Oncol 2015 Feb 29;33(5):403-10. Epub 2014 Dec 29.

Christoph Röllig, Martin Bornhäuser, Michael Kramer, Christian Thiede, Uwe Platzbecker, Martin Wermke, Friedrich Stölzel, Malte von Bonin, Markus Schaich, Johannes Schetelig, and Gerhard Ehninger, Medizinische Klinik und Poliklinik I, Universitätsklinikum der Technischen Universität Dresden; Johannes Schetelig, DKMS, German Bone Marrow Donor Center, Dresden; Anthony D. Ho and Alwin Krämer, Medizinische Universitätsklinik, Abteilung Innere Medizin V, Heidelberg; Kerstin Schäfer-Eckart and Hannes Wandt, 5. Medizinische Klinik, Klinikum Nürnberg, Nürnberg; Mathias Hänel, Klinik für Innere Medizin III, Klinikum Chemnitz, Chemnitz; Hermann Einsele, Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg; Walter E. Aulitzky, Robert-Bosch-Krankenhaus, Stuttgart; Norbert Schmitz, Abteilung für Hämatologie, Onkologie und Stammzelltransplantation, ASKLEPIOS Klinik St Georg, Hamburg; Wolfgang E. Berdel, Matthias Stelljes, and Utz Krug, Medizinische Klinik A, Universitätsklinikum Münster, Münster; Carsten Müller-Tidow, Universitätsklinik und Poliklinik für Innere Medizin IV, Universitätsklinikum Halle, Halle (Saale); Claudia D. Baldus, Medizinische Klinik III, Charité-Universitätsmedizin Berlin, Charité Centrum 14, Campus Benjamin Franklin, Berlin; Stefan W. Krause, Medizinische Klinik 5, Universitätsklinikum Erlangen, Erlangen; and Hubert Serve, Medizinische Klinik II, Universitätsklinikum Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1200/JCO.2013.54.4973DOI Listing
February 2015

Sustained complete molecular remission after imatinib discontinuation in children with chronic myeloid leukemia.

Pediatr Blood Cancer 2014 Nov 9;61(11):2080-2. Epub 2014 May 9.

Department of Pediatric Hematology and Oncology, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1002/pbc.25090DOI Listing
November 2014

Monitoring of acute myeloid leukemia patients after allogeneic stem cell transplantation employing semi-automated CD34+ donor cell chimerism analysis.

Ann Hematol 2014 Feb 19;93(2):279-85. Epub 2013 Dec 19.

Klinik für Hämatologie, Onkologie und Immunologie, University Hospital Giessen and Marburg, Campus Marburg, Baldingerstraße, 35043, Marburg, Germany.

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http://dx.doi.org/10.1007/s00277-013-1961-4DOI Listing
February 2014

In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice.

PLoS One 2013 9;8(4):e60680. Epub 2013 Apr 9.

Regeneration in Hematopoiesis, Center for Regenerative Therapies Dresden - CRTD, DFG Research Center and Cluster of Excellence, Technische Universität Dresden, Dresden, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060680PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621959PMC
October 2013

Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells.

J Cell Sci 2013 Oct 13;126(Pt 20):4746-55. Epub 2013 Aug 13.

Institute of Molecular Cell Biology, Center for Molecular Biomedicine, Jena University Hospital, 07743 Jena, Germany.

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http://dx.doi.org/10.1242/jcs.131789DOI Listing
October 2013

The level of residual disease based on mutant NPM1 is an independent prognostic factor for relapse and survival in AML.

Blood 2013 Jul 8;122(1):83-92. Epub 2013 May 8.

Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der Technischen Universität, Dresden, Germany.

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http://dx.doi.org/10.1182/blood-2012-10-461749DOI Listing
July 2013

Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate.

Acta Neuropathol 2012 Dec 2;124(6):883-91. Epub 2012 Nov 2.

Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00401-012-1060-yDOI Listing
December 2012

Aberrant methylation of the M-type phospholipase A(2) receptor gene in leukemic cells.

BMC Cancer 2012 Dec 5;12:576. Epub 2012 Dec 5.

Institut für Klinische Chemie und Laboratoriumsmedizin, Technische Universität Dresden, Fetscherstrasse 74, D-01307, Dresden, Germany.

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http://dx.doi.org/10.1186/1471-2407-12-576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561142PMC
December 2012

Genomic BCR-ABL1 breakpoints in pediatric chronic myeloid leukemia.

Genes Chromosomes Cancer 2012 Nov 9;51(11):1045-53. Epub 2012 Aug 9.

Department of Pediatrics, University Hospital Erlangen, Germany.

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http://dx.doi.org/10.1002/gcc.21989DOI Listing
November 2012

Mutant DNMT3A: teaming up to transform.

Authors:
Christian Thiede

Blood 2012 Jun;119(24):5615-7

University Hospital Carl Gustave Carus, University of Technics.

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http://dx.doi.org/10.1182/blood-2012-04-423905DOI Listing
June 2012

Prediction of post-remission survival in acute myeloid leukaemia: a post-hoc analysis of the AML96 trial.

Lancet Oncol 2012 Feb 22;13(2):207-14. Epub 2011 Dec 22.

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie-IBE, Ludwig-Maximilians-Universität, Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045117032
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http://dx.doi.org/10.1016/S1470-2045(11)70326-6DOI Listing
February 2012

Genetic variations of interleukin-23R (1143A>G) and BPI (A645G), but not of NOD2, are associated with acute graft-versus-host disease after allogeneic transplantation.

Biol Blood Marrow Transplant 2010 Dec 9;16(12):1718-27. Epub 2010 Jun 9.

Department of Medicine I, University Hospital Carl-Gustav-Carus, Fetscherstraße 74, Dresden, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2010.06.001DOI Listing
December 2010