Christian T Ruff

Christian T Ruff

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Christian T Ruff

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Clinical outcomes, edoxaban concentration, and anti-factor Xa activity of Asian patients with atrial fibrillation compared with non-Asians in the ENGAGE AF-TIMI 48 trial.

Eur Heart J 2019 May;40(19):1518-1527

Division of Cardiovascular Medicine, TIMI Study Group, Brigham and Women's Hospital, 60 Fenwood Road, 7th Floor, Suite 7022, Boston, MA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehy807DOI Listing
May 2019

Relationship between body mass index and outcomes in patients with atrial fibrillation treated with edoxaban or warfarin in the ENGAGE AF-TIMI 48 trial.

Eur Heart J 2019 May;40(19):1541-1550

TIMI Study Group, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Suite 7022, Boston, MA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehy861DOI Listing
May 2019

Edoxaban in atrial fibrillation patients with established coronary artery disease: Insights from ENGAGE AF-TIMI 48.

Eur Heart J Acute Cardiovasc Care 2019 Mar 24;8(2):176-185. Epub 2018 Jul 24.

1 TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1177/2048872618790561DOI Listing
March 2019

Edoxaban and implantable cardiac device interventions: insights from the ENGAGE AF-TIMI 48 trial.

Europace 2019 Feb;21(2):306-312

Cardiovascular Division, TIMI Study Group, Brigham and Women's Hospital, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/europace/euy253DOI Listing
February 2019

Performance of the ABC Scores for Assessing the Risk of Stroke or Systemic Embolism and Bleeding in Patients With Atrial Fibrillation in ENGAGE AF-TIMI 48.

Circulation 2019 Feb;139(6):760-771

TIMI Study Group, Cardiovascular Division, Department of Medicine (D.D.B., C.T.R., R.P.G., F.N., E.M.A., E.B., D.A.M.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363338PMC
February 2019

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.

N Engl J Med 2019 01 10;380(4):347-357. Epub 2018 Nov 10.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital (S.D.W., M.P.B., T.A.Z., J.F.K., S.A.M., D.L.B., C.T.R., M.S.S.), and the Cardiology Division, Massachusetts General Hospital (M.G.S.) - both in Boston; the Diabetes Unit, Hadassah Hebrew University Hospital, Jerusalem (I.R., O.M., A.C.); the Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (E.T.K.); Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.); the Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (D.K.M.); Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom (J.P.H.W.); and AstraZeneca Gothenburg, Mölndal, Sweden (I.A.M.G.-N., M.F., P.A.J., A.-M.L.).

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http://dx.doi.org/10.1056/NEJMoa1812389DOI Listing
January 2019

Lorcaserin and Renal Outcomes in Obese and Overweight Patients in the CAMELLIA-TIMI 61 Trial.

Circulation 2019 Jan;139(3):366-375

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (B.M.S., E.A.B., A.Q., S.A.M., K.I., M.P.B., C.T.R., M.S.S., S.D.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038341DOI Listing
January 2019

Pharmacogenetics of Warfarin Therapy.

Authors:
Christian T Ruff

Clin Chem 2018 Nov 25;64(11):1558-1559. Epub 2018 Jun 25.

TIMI Study Group, Cardiovascular Medicine Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1373/clinchem.2017.284927DOI Listing
November 2018

Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report.

Chest 2018 Nov 22;154(5):1121-1201. Epub 2018 Aug 22.

Uniformed Services University of the Health Sciences, F. Edward Hebert School of Medicine, Bethesda, MD.

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http://dx.doi.org/10.1016/j.chest.2018.07.040DOI Listing
November 2018

The efficacy and safety of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation and coronary artery disease: A meta-analysis of randomized trials.

Eur Heart J Acute Cardiovasc Care 2018 Oct 15:2048872618796990. Epub 2018 Oct 15.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1177/2048872618796990DOI Listing
October 2018

Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients.

N Engl J Med 2018 09 26;379(12):1107-1117. Epub 2018 Aug 26.

From the Thrombolysis in Myocardial Infarction (TIMI) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston (E.A.B., S.D.W., J.K., K.I., A.Q., M.P.B., C.T.R., M.S.S., B.M.S.); the Cardiovascular Division, University of Texas Southwestern Medical Center, Dallas (D.K.M.); the Section of Endocrinology, Yale School of Medicine, New Haven, CT (S.E.I.); the Department of Medicine, University of Minnesota, Minneapolis (C.L.F.); the Partners Clinical Research Centre, Nassau, Bahamas (C.B.); the Department of Cardiology, Postgraduate Medical School, Grochowski Hospital, Warsaw, Poland (A.B.); Cardiolink Clinical Trials, Monterrey, Mexico (A.G.-C.); McMaster University, Brampton, ON (M.G.), and the Division of Endocrinology and Metabolism, St. Michael's Hospital, University of Toronto, Toronto (L.A.L.) - both in Canada; MedStar Health Research Institute, Hyattsville, MD (N.J.W.); the Cardiology Department, Auckland City Hospital, Auckland, New Zealand (H.D.W.); Eisai, Woodcliff Lake, NJ (T.P., B.F., W.M., C.P., S.D.); National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney (A.C.K.); and the Translational Research Institute for Metabolism and Diabetes, Florida Hospital and the Sanford-Burnham Institute, Winter Park (S.R.S.).

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http://dx.doi.org/10.1056/NEJMoa1808721DOI Listing
September 2018

Edoxaban Versus Warfarin in Latin American Patients With Atrial Fibrillation: The ENGAGE AF-TIMI 48 Trial.

J Am Coll Cardiol 2018 Sep;72(13):1466-1475

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/rgiugliano.

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http://dx.doi.org/10.1016/j.jacc.2018.07.037DOI Listing
September 2018

Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial.

Thromb Haemost 2018 06 3;118(6):1001-1008. Epub 2018 May 3.

Department of Medicine, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1055/s-0038-1645856DOI Listing
June 2018

Gastrointestinal Bleeding With Edoxaban Versus Warfarin: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis In Myocardial Infarction).

Circ Cardiovasc Qual Outcomes 2018 May;11(5):e003998

TIMI Study Group, Division of Cardiovascular Medicine and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (C.T.R., F.N., E.M.A., E.B., R.P.G.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.117.003998DOI Listing
May 2018

Clinical events after interruption of anticoagulation in patients with atrial fibrillation: An analysis from the ENGAGE AF-TIMI 48 trial.

Int J Cardiol 2018 04 2;257:102-107. Epub 2018 Feb 2.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.01.065DOI Listing
April 2018

Personalized Anticoagulation: Optimizing Warfarin Management Using Genetics and Simulated Clinical Trials.

Circ Cardiovasc Genet 2017 Dec;10(6)

From the Aurora Research Institute, Aurora Health Care, Milwaukee, WI (K.R., J.A.W.); Brigham and Women's Hospital, Harvard Medical School, Boston, MA (C.T.R., P.J.T.); School of Nursing and Institute for Health Informatics, University of Minnesota, Minneapolis (C.-L.C.); and University of Wisconsin, Milwaukee (P.J.T.).

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https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.117.001
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http://dx.doi.org/10.1161/CIRCGENETICS.117.001804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734112PMC
December 2017

First experience with edoxaban and atrial fibrillation ablation - Insights from the ENGAGE AF-TIMI 48 trial.

Int J Cardiol 2017 Oct 2;244:192-195. Epub 2017 Jun 2.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.05.098DOI Listing
October 2017

Edoxaban in patients with atrial fibrillation.

Ther Adv Cardiovasc Dis 2017 Mar 1;11(3):81-90. Epub 2016 Aug 1.

Brigham and Women's Hospital and Harvard Medical School Boston, TIMI Study Group, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA.

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http://dx.doi.org/10.1177/1753944715622130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942795PMC
March 2017

A novel risk prediction score in atrial fibrillation for a net clinical outcome from the ENGAGE AF-TIMI 48 randomized clinical trial.

Eur Heart J 2017 Mar;38(12):888-896

Department of Medicine, TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/ehw565DOI Listing
March 2017

Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves.

Circulation 2017 03 16;135(13):1273-1275. Epub 2017 Feb 16.

From Brigham & Women's Hospital, Harvard Medical School, Boston, MA (A.P.C.); Institute of Cardiology and Center of Excellence on Aging, G. d'Annunzio University, Chieti, Italy (R.D.C., G.R.); Mount Sinai Hospital, Icahn School of Medicine at Mount Sinai, New York (J.L.H.); TIMI Study Group (Thrombolysis in Myocardial Infarction), Boston, MA (C.T.R., M.T., F.N., E.A., R.P.G.); and Daiichi Sankyo Pharma Development, Edison, NJ (M.P.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026714DOI Listing
March 2017

Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial.

J Am Coll Cardiol 2017 Mar;69(11):1372-1382

Cardiovascular Medicine Division, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.12.031DOI Listing
March 2017

Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation: Results From the ENGAGE AF-TIMI 48 Trial (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).

Circ Arrhythm Electrophysiol 2017 01;10(1)

From the Department of Medicine, UTSouthwestern Medical Center, Dallas, TX (M.S.L.); TIMI Study Group, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., B.M.S., A.E.C., S.A.M., E.M.A., E.B.); Department of Medicine, University of Oulu, Finland (H.H.); Oulu University Hospital, Finland (H.H.); Heart and Health Foundation of Turkey, Ankara (A.O.); Daiichi-Sankyo Pharma Development, Munich, Germany (H.L.); and Daiichi-Sankyo Pharma Development, Edison, NJ (M.F.M.).

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http://dx.doi.org/10.1161/CIRCEP.116.004267DOI Listing
January 2017

Cardiovascular Biomarker Score and Clinical Outcomes in Patients With Atrial Fibrillation: A Subanalysis of the ENGAGE AF-TIMI 48 Randomized Clinical Trial.

JAMA Cardiol 2016 Dec;1(9):999-1006

TIMI Study Group 2Cardiovascular Medicine Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamacardio.2016.3311DOI Listing
December 2016

Non-Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation.

Hematol Oncol Clin North Am 2016 10;30(5):1019-34

Cardiovascular Division, TIMI Study Group, Brigham and Women's Hospital, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2016.05.002DOI Listing
October 2016

Efficacy and safety of edoxaban compared with warfarin in patients with atrial fibrillation and heart failure: insights from ENGAGE AF-TIMI 48.

Eur J Heart Fail 2016 09 28;18(9):1153-61. Epub 2016 Jun 28.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, 350 Longwood Avenue, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1002/ejhf.595DOI Listing
September 2016

Edoxaban Versus Warfarin in Atrial Fibrillation Patients at Risk of Falling: ENGAGE AF-TIMI 48 Analysis.

J Am Coll Cardiol 2016 09;68(11):1169-1178

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.06.034DOI Listing
September 2016

The Reality of "Real-World" Data: More Questions Than Answers.

Authors:
Christian T Ruff

J Am Coll Cardiol 2016 09;68(13):1402-1403

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.06.063DOI Listing
September 2016

Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events: Findings From ENGAGE AF-TIMI 48 (Effective Anticoagulation With Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48).

Stroke 2016 08 7;47(8):2075-82. Epub 2016 Jul 7.

From the Massachusetts General Hospital, Boston (N.S.R., S.S., A.B.S.); TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston MA (R.P.G., C.T.R., S.A.M., A.E.C., A.D.N., E.M.A., E.B.); Heart Institute (InCor), University of São Paulo Medical School, Brazil (J.C.N.); CARE Musheerabad, Hyderabad, India (B.S.); and Daiichi-Sankyo Pharma Development, Edison, NJ (M.F.M.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013540DOI Listing
August 2016

Impact of Renal Function on Outcomes With Edoxaban in the ENGAGE AF-TIMI 48 Trial.

Circulation 2016 Jul;134(1):24-36

From the TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://circ.ahajournals.org/content/circulationaha/134/1/24.
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022361DOI Listing
July 2016

Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF-TIMI 48 Trial.

J Am Heart Assoc 2016 07 8;5(7). Epub 2016 Jul 8.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA Department of Medicine, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1161/JAHA.116.003735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015407PMC
July 2016

Management of Bleeding With Non-Vitamin K Antagonist Oral Anticoagulants in the Era of Specific Reversal Agents.

Circulation 2016 Jul;134(3):248-61

From TIMI Study Group, Cardiovascular Medicine Division, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.021831DOI Listing
July 2016

The Prognostic Significance of Cardiac Structure and Function in Atrial Fibrillation: The ENGAGE AF-TIMI 48 Echocardiographic Substudy.

J Am Soc Echocardiogr 2016 06 20;29(6):537-44. Epub 2016 Apr 20.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1016/j.echo.2016.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893881PMC
June 2016

Cost-effectiveness of edoxaban vs warfarin in patients with atrial fibrillation based on results of the ENGAGE AF-TIMI 48 trial.

Am Heart J 2015 Dec 25;170(6):1140-50. Epub 2015 Sep 25.

Saint Luke's Mid America Heart Institute, Kansas City, MO; University of Missouri - Kansas City School of Medicine, Kansas City, MO.

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http://dx.doi.org/10.1016/j.ahj.2015.09.011DOI Listing
December 2015

The Challenge of Getting it Just Right: Optimizing Long-Term Antithrombotic Therapy After Acute Coronary Syndrome.

Authors:
Christian T Ruff

J Am Coll Cardiol 2015 Aug;66(7):788-790

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097150393
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http://dx.doi.org/10.1016/j.jacc.2015.06.1082DOI Listing
August 2015

Edoxaban vs. warfarin in vitamin K antagonist experienced and naive patients with atrial fibrillation†.

Eur Heart J 2015 Jun 16;36(23):1470-7. Epub 2015 Feb 16.

TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, 350 Longwood Avenue, 1st Floor, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/ehv014DOI Listing
June 2015

Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial.

Lancet 2015 Jun 11;385(9984):2280-7. Epub 2015 Mar 11.

TIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(14)61994-2DOI Listing
June 2015

Cerebrovascular events in 21 105 patients with atrial fibrillation randomized to edoxaban versus warfarin: Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48.

Stroke 2014 Aug 19;45(8):2372-8. Epub 2014 Jun 19.

From the Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (R.P.G., C.T.R., S.D.W., C.L., N.D., S.A.M., L.T.G., E.M.A., E.B.); Department of Neurology, Massachusetts General Hospital, Boston (N.S.R., S.S.); Biostatistics, Quintiles, Inc, Durham, NC (J.M.B.); and Daiichi Sankyo, Inc, Pharma Development, Edison, NJ (A.D., J.D., M.S., M.M.).

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http://dx.doi.org/10.1161/STROKEAHA.114.006025DOI Listing
August 2014

New oral anticoagulants in patients with atrial fibrillation - Authors'reply.

Lancet 2014 Jul;384(9937):25-6

Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/S0140-6736(14)61106-5DOI Listing
July 2014

Variability of individual platelet reactivity over time in patients treated with clopidogrel: insights from the ELEVATE-TIMI 56 trial.

J Am Coll Cardiol 2014 Jul;64(4):361-8

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.03.051DOI Listing
July 2014

Left atrial structure and function in atrial fibrillation: ENGAGE AF-TIMI 48.

Eur Heart J 2014 Jun 2;35(22):1457-65. Epub 2013 Dec 2.

Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA

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http://dx.doi.org/10.1093/eurheartj/eht500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048534PMC
June 2014

Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial.

J Thromb Thrombolysis 2014 Apr;37(3):310-6

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, First Floor, Boston, MA, USA,

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http://dx.doi.org/10.1007/s11239-013-0968-yDOI Listing
April 2014

Diagnostic performance of copeptin in patients with acute nontraumatic chest pain: BWH-TIMI ED chest pain study.

Clin Cardiol 2014 Apr 22;37(4):227-32. Epub 2014 Jan 22.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/clc.22244DOI Listing
April 2014

Long-term cardiovascular outcomes in patients with atrial fibrillation and atherothrombosis in the REACH Registry.

Int J Cardiol 2014 Jan 25;170(3):413-8. Epub 2013 Nov 25.

Department of Medicine and the Metabolic Disease Center, Tokai University School of Medicine, Kanagawa, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S01675273130204
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http://dx.doi.org/10.1016/j.ijcard.2013.11.030DOI Listing
January 2014

Evaluation of the diagnostic performance of heart-type fatty acid binding protein in the BWH-TIMI ED chest pain study.

J Thromb Thrombolysis 2013 Nov;36(4):361-7

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, 1st Floor Offices, Boston, MA, 02115, USA,

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http://dx.doi.org/10.1007/s11239-013-0870-7DOI Listing
November 2013

Edoxaban versus warfarin in patients with atrial fibrillation.

N Engl J Med 2013 Nov 19;369(22):2093-104. Epub 2013 Nov 19.

From Brigham and Women's Hospital and Harvard Medical School, Boston (R.P.G., C.T.R., E.B., S.A.M., S.D.W., L.T.G., E.M.A.); Mount Sinai Medical Center, New York (J.L.H.); University Hospitals Case Medical Center, Cleveland (A.L.W.); Thomas Jefferson Medical College, Philadelphia (M.D.E.); McMaster University, Hamilton, ON, Canada (J.I.W.); University Hospital, Jihlavska, Brno, Czech Republic (J.S.); Institute of Cardiology, Warsaw, Poland (W.R.); Cardiology Research Center, Moscow (M.R.); National Hospital Organization, Osaka National Hospital, Osaka, Japan (Y.K.); Quintiles, Durham, NC (J.B., S.P.P.); and Daiichi Sankyo Pharma Development, Edison, NJ (M.S., I.P., J.J.H., M.M.).

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http://dx.doi.org/10.1056/NEJMoa1310907DOI Listing
November 2013

Central versus local adjudication of myocardial infarction in a cardiac biomarker trial.

Am Heart J 2013 Mar 26;165(3):273-279.e1. Epub 2013 Jan 26.

Department of Emergency Medicine, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1016/j.ahj.2012.12.012DOI Listing
March 2013

Diagnostic evaluation of the MRP-8/14 for the emergency assessment of chest pain.

J Thromb Thrombolysis 2012 Aug;34(2):229-34

TIMI Study Group, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 350 Longwood Avenue, 1st Floor Offices, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s11239-012-0705-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113032PMC
August 2012

Cardiology patient page: stroke prevention in atrial fibrillation.

Authors:
Christian T Ruff

Circulation 2012 Apr;125(16):e588-90

Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.067843DOI Listing
April 2012

Safety and efficacy of prasugrel compared with clopidogrel in different regions of the world.

Int J Cardiol 2012 Mar 19;155(3):424-9. Epub 2010 Nov 19.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ijcard.2010.10.040DOI Listing
March 2012

The evolving epidemiology of acute coronary syndromes.

Nat Rev Cardiol 2011 Mar 21;8(3):140-7. Epub 2010 Dec 21.

TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/nrcardio.2010.199DOI Listing
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Will warfarin ever be replaced?

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TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/1074248410366448DOI Listing
September 2010

TIMI risk index and the benefit of enoxaparin in patients with ST-elevation myocardial infarction.

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TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass 02115, USA.

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November 2007

Inhibition of tissue factor as a novel approach to anticoagulation in patients with coronary artery disease.

Future Cardiol 2006 Jan;2(1):85-91

Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

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https://www.futuremedicine.com/doi/10.2217/14796678.2.1.85
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January 2006

Molecular characterization of preintegration latency in human immunodeficiency virus type 1 infection.

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Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1128/jvi.76.17.8518-8513.2002DOI Listing
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Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication.

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Department of Medicine, Johns Hopkins University School of Medicine, Johns Hopkins University School of Public Health, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1128/jvi.76.8.4138-4144.2002DOI Listing
April 2002