Publications by authors named "Christian Roth"

100Publications

New Nonsense Variant c.2983G>T; p.Glu995* in the CACNA1A Gene Causes Progressive Autosomal Dominant Ataxia.

J Mov Disord 2020 Oct 31. Epub 2020 Oct 31.

Department of Neurology and Neurophysiology, DRK-Kliniken Nordhessen, Kassel, Germany.

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http://dx.doi.org/10.14802/jmd.20082DOI Listing
October 2020

Pilot multi-site and reproducibility study of hypothalamic gliosis in children.

Pediatr Obes 2020 Oct 20:e12732. Epub 2020 Oct 20.

Department of Medicine, University of Washington, Seattle, Washington State, USA.

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http://dx.doi.org/10.1111/ijpo.12732DOI Listing
October 2020

Connections Between Obesity and Puberty: Invited by Manuel Tena-Sempere, Cordoba.

Curr Opin Endocr Metab Res 2020 Oct 27;14:160-168. Epub 2020 Aug 27.

Department of Pediatrics, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1016/j.coemr.2020.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543977PMC
October 2020

A phase 3 randomized clinical trial using a once-weekly glucagon-like peptide-1 receptor agonist in adolescents and young adults with hypothalamic obesity.

Diabetes Obes Metab 2020 Oct 7. Epub 2020 Oct 7.

McNeely Pediatric Diabetes Center and Endocrinology Clinic, Children's Minnesota, St. Paul, Minnesota.

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http://dx.doi.org/10.1111/dom.14224DOI Listing
October 2020

Outpacing movement - ultrafast volume coverage in neuropediatric magnetic resonance imaging.

Pediatr Radiol 2020 11 19;50(12):1751-1756. Epub 2020 Sep 19.

Department of Pediatric Radiology, University of Leipzig, Liebigstraße 20a, 04103, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00247-020-04771-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604272PMC
November 2020

Frequency and Timing of Endovascular Therapy in Acute Stroke Patients: A Population-Based Analysis Using the Bremen Stroke Register.

Neuroepidemiology 2020 9;54(5):398-403. Epub 2020 Sep 9.

Department of Neuroradiology, Klinikum Bremen-Mitte, Bremen, Germany.

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http://dx.doi.org/10.1159/000509430DOI Listing
September 2020

Child neurobiology impacts success in family-based behavioral treatment for children with obesity.

Int J Obes (Lond) 2020 Oct 26;44(10):2011-2022. Epub 2020 Jul 26.

Seattle Children's Research Institute, 1900 Ninth Ave, Seattle, WA, 98101, USA.

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http://dx.doi.org/10.1038/s41366-020-0644-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530004PMC
October 2020

Treatment for secondary deterioration in idiopathic normal pressure hydrocephalus in the later course of the disease: a retrospective analysis.

Acta Neurochir (Wien) 2020 10 4;162(10):2431-2439. Epub 2020 Jul 4.

Department of Neurosurgery, Klinikum Kassel, Moencheberg Str. 41-43, 34125, Kassel, Germany.

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http://dx.doi.org/10.1007/s00701-020-04475-7DOI Listing
October 2020

Predicting the presence of coronary artery disease by transesophageal echocardiography.

Wien Klin Wochenschr 2020 Jun 12. Epub 2020 Jun 12.

Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-020-01686-xDOI Listing
June 2020

Factors influencing intracranial pressure (ICP) during percutaneous tracheostomy.

Clin Neurol Neurosurg 2020 Aug 23;195:105869. Epub 2020 Apr 23.

Department of Neurology, DRK-Kliniken Nordhessen, Hansteinstraße 29, 34121 Kassel, Germany; Department of Neurology, Philipps University Marburg, Baldingerstraße, 35037 Marburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2020.105869DOI Listing
August 2020

Impact of treatment strategies on long-term outcome of CTO patients.

Eur J Intern Med 2020 Jul 14;77:97-104. Epub 2020 Mar 14.

Department of Internal Medicine II, Division of Cardiology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2020.03.008DOI Listing
July 2020

Acute symptomatic seizures in intracerebral and subarachnoid hemorrhage: A population study of 19,331 patients.

Epilepsy Res 2020 03 5;161:106286. Epub 2020 Feb 5.

Department of Neurology and Epilepsy Center Frankfurt Rhine-Main, Goethe University Frankfurt, Frankfurt am Main, Germany; LOEWE Center for Personalized Translational Epilepsy Research (CePTER), Goethe University Frankfurt, Frankfurt am Main, Germany; Department of Neurology and Epilepsy Center Hessen, Philipps University Marburg, Marburg (Lahn), Germany.

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http://dx.doi.org/10.1016/j.eplepsyres.2020.106286DOI Listing
March 2020

[Bilateral idiopathic chondrolysis of the hips - A case report of an adolescent patient].

Orthopade 2020 Jun;49(6):538-542

Klinik und Poliklinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinikum Leipzig, Leipzig, Deutschland.

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http://dx.doi.org/10.1007/s00132-020-03885-wDOI Listing
June 2020

Defining and expanding the phenotype of -associated developmental epileptic encephalopathy.

Neurol Genet 2019 Dec 10;5(6):e373. Epub 2019 Dec 10.

Department of Epilepsy Genetics and Precision Medicine (K.J.M., E.G., G.R., R.S.M.), The Danish Epilepsy Centre Filadelfia, Dianalund, Denmark; Institute for Regional Health Services (K.J.M., E.G., R.S.M.), University of Southern Denmark, Odense; Institute of Human Genetics (D.M., R. Jamra, A.F., J.R.L.), University of Leipzig Medical Center, Germany; Institute of Structural Biology (R. Janowski, D.N.), Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany; Department of Paediatric Radiology (C.R.), University of Leipzig Medical Center, Germany; Department of Epilepsy, Sleep and Pediatric Neurophysiology (J.T.), Lyon University Hospital, France; Neuropediatric Unit (A.-L.P., D.M.V., G.L.), Lyon University Hospital, France; Department of Medical Genetics (N.C., G.L.), Lyon University Hospital, France; GenDev Team (N.C.), CNRS UMR 5292, INSERM U1028, CNRL and University of Lyon, France; Department of Genetics (E.B.), University Medical Center Utrecht, The Netherlands; Department of Child Neurology (K.G.), Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands; Department of Paediatrics (A.P.B.), Copenhagen University Hospital Rigshospitalet, Denmark; Baylor College of Medicine (S.M., K.N.), Children's Hospital of San Antonio; Undiagnosed Diseases Program (G.B., C.P.), Genetic Services of Western Australia, Department of Health, Government of Western Australia, Perth; Western Australian Register of Developmental Anomalies (G.B., D.G.), Australia; Telethon Kids Institute and the School of Paediatrics and Child Health (G.B.), University of Western Australia, Perth; Linear Clinical Research (L.D.), WA, Australia; Center of Human Genetics (S.S), Jena University Hospital, Germany; Department of Neuropediatrics (A.D.), Jena University Hospital, Germany; Division of Neurology (K.L.H.), Children's Hospital of Philadelphia, PA; Division of Neuropediatrics (A.M.), University of Leipzig Medical Center, Germany; Amplexa Genetics (H.H.), Odense, Denmark; Clinic for Children (H.H.), Værløse, Denmark; Center for Integrative Brain Research (G.M.), Seattle Children's Research Institute, WA; Department of Pediatrics (G.M.), University of Washington, Seattle; Medical Genetics Unit (F.B.), Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; Istituto Dermopatico dell'Immacolata (F.B.), IDI-IRCCS, Rome, Italy; Institute of Human Genetics (T.B., M.H.), University Medical Center Hamburg-Eppendorf, Germany; Childrens Hospital (J.D.), University Medical Center Hamburg-Eppendorf, Germany; University of Copenhagen (G.R.), Denmark; Institute for Human Genetics (P.M.), University Hospital Magdeburg, Germany; Children's Hospital A. Meyer (R.G., A.V.), University of Florence, Italy; and Institute of Pharmaceutical Biotechnology (D.N.), Ulm University, Germany.

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http://dx.doi.org/10.1212/NXG.0000000000000373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927360PMC
December 2019

An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq.

Acta Crystallogr F Struct Biol Commun 2020 Feb 5;76(Pt 2):81-85. Epub 2020 Feb 5.

School of Chemistry, Cardiff University, Park Place, Cardiff CF10 3AT, UK.

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http://dx.doi.org/10.1107/S2053230X20001181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010360PMC
February 2020

The current status and further prospects for lung magnetic resonance imaging in pediatric radiology.

Pediatr Radiol 2020 05 29;50(5):734-749. Epub 2020 Jan 29.

Department of Pediatric Radiology, University of Leipzig, Liebigstraße 20a, 04103, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00247-019-04594-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150663PMC
May 2020

Myasthenic crisis demanding mechanical ventilation: A multicenter analysis of 250 cases.

Neurology 2020 01 4;94(3):e299-e313. Epub 2019 Dec 4.

From the Department of Neurology (B.N., K.A., A.V.), University Medical Center Regensburg; NeuroCure Clinical Research Center (P.M., S.K., A.M.) and Departments of Neurology and Experimental Neurology (P.M., A.M.), Charité-Universitätsmedizin Berlin; Berlin Institute of Health (P.M., S.K., A.M.); Department of Neurology (S.S., J.B.), Heidelberg University Hospital; Department of Neurology (J.B.), Klinikum Kassel; Department of Mathematics and Computer Science (U.N.), Philipps-Universität Marburg; Department of Neurology (H.B.H., S.T.G.), University Hospital Erlangen; Department of Neurology (A.T., A.S.), HELIOS Klinikum Erfurt; Department of Neurology (J.D., C.R.), DRK-Kliniken Nordhessen, Kassel; Department of Neurology (H.S., E.S.), University Hospital, Technische Universität Dresden; Department of Neurology (H.S.), Klinikum Augsburg; Department of Neurology (E.S.), Städtisches Klinikum Dresden; Department of Neurology (H.F.), University of Freiburg; Department of Neurology (C.F.), St. Josef-Hospital, Ruhr-University Bochum; Department of Neurology (A.A.), Kliniken Maria Hilf GmbH Mönchengladbach; Hans Berger Department of Neurology (J.Z.), Jena University Hospital; Department of Neurology (C.D., H.R.S.), University of Cologne; and Department of Neurology (C.D.), LVR-Klinik Bonn, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000008688DOI Listing
January 2020

Inducible Nitric Oxide Synthase and L-Arginine Optimizes Nitric Oxide Bioavailability in Ischemic Tissues Under Diabetes Mellitus Type 1.

Ann Plast Surg 2020 01;84(1):106-112

From the Department of Hand, Plastic, and Reconstructive Surgery, BG Clinic Ludwigshafen, University of Heidelberg, Ludwigshafen.

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http://dx.doi.org/10.1097/SAP.0000000000002121DOI Listing
January 2020

Safety and effectiveness of CATCH+ as a first-line device for revascularization in the treatment of acute ischemic stroke.

J Neuroradiol 2019 Sep 17. Epub 2019 Sep 17.

Clinic for Diagnostic and Interventional Neuroradiology, Klinikum Bremen Mitte, Bremen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neurad.2019.07.009DOI Listing
September 2019

Childhood Dystonia-Parkinsonism Following Infantile Spasms-Clinical Clue to Diagnosis in Early Beta-Propeller Protein-Associated Neurodegeneration.

Neuropediatrics 2020 02 10;51(1):22-29. Epub 2019 Sep 10.

Department of Pediatric Neurology, Leipzig University Hospital for Children and Adolescents, Leipzig, Sachsen, Germany.

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http://dx.doi.org/10.1055/s-0039-1696688DOI Listing
February 2020

Conservative versus operative treatment in supratentorial intracerebral hemorrhage - A survey among neurosurgeons and neurologists in Germany.

Clin Neurol Neurosurg 2019 Nov 27;186:105502. Epub 2019 Aug 27.

Ethianum Clinic for Plastic and Reconstructive Surgery, Aesthetic and Preventive Medicine at Heidelberg University Hospital, Heidelberg, Germany; Department of Hand, Plastic and Reconstructive Surgery, Microsurgery Burn Centre, BG Trauma Centre, Ludwigshafen/Rhine, Germany, University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.clineuro.2019.105502DOI Listing
November 2019

Wie bei Kindern ein gutes Lungen-MRT gelingt.

Rofo 2019 Sep 20;191(S 02):S114-S115. Epub 2019 Aug 20.

Abteilung Kinderradiologie, Universität Leipzig.

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http://dx.doi.org/10.1055/a-0943-1168DOI Listing
September 2019

Transcriptome maps of general eukaryotic RNA degradation factors.

Elife 2019 05 28;8. Epub 2019 May 28.

Department of Molecular Biology, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.

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http://dx.doi.org/10.7554/eLife.47040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570525PMC
May 2019

The role of the socio-economic environment on medical outcomes after ST-segment elevation myocardial infarction.

BMC Public Health 2019 May 23;19(1):630. Epub 2019 May 23.

Wittgenstein Centre (WU, VID/ÖAW, IIASA), Institute for Applied Systems Analysis and Vienna Institute of Demography, Welthandelsplatz 2/Level 2, 1020, Vienna, Austria.

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http://dx.doi.org/10.1186/s12889-019-6966-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533747PMC
May 2019

Mechanical thrombectomy in nonagenarians with acute ischemic stroke.

J Neurointerv Surg 2019 Nov 27;11(11):1091-1094. Epub 2019 Apr 27.

Department of Diagnostic and Interventional Neuroradiology, Klinikum Bremen-Mitte GmbH, Bremen, Germany.

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http://dx.doi.org/10.1136/neurintsurg-2019-014785DOI Listing
November 2019

Hypothalamic Obesity: Prologue and Promise.

Horm Res Paediatr 2019 18;91(2):128-136. Epub 2019 Mar 18.

Division of Endocrinology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1159/000496564DOI Listing
December 2019

Progress of intracranial pressure and cerebral perfusion pressure in patients during the development of brain death.

J Neurol Sci 2019 Mar 29;398:171-175. Epub 2019 Jan 29.

Department of Anesthesiology, University of Marburg, Marburg, Germany; Pain Center, Kassel, Germany.

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http://dx.doi.org/10.1016/j.jns.2019.01.048DOI Listing
March 2019

Rodent models of diet-induced type 2 diabetes mellitus: A literature review and selection guide.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):195-200. Epub 2018 Jul 31.

Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, Ludwigshafen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S18714021183029
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http://dx.doi.org/10.1016/j.dsx.2018.07.020DOI Listing
May 2019

Intraindividual Variation in Markers of Intestinal Permeability and Adipose Tissue Inflammation in Healthy Normal-Weight to Obese Adults.

Cancer Epidemiol Biomarkers Prev 2019 03 20;28(3):610-615. Epub 2018 Dec 20.

Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401228PMC
March 2019

Is there a causal relationship between obesity and puberty?

Lancet Child Adolesc Health 2019 01 14;3(1):44-54. Epub 2018 Nov 14.

Center for Integrative Brain Research, Division of Endocrinology, Seattle Children's Research Institute, Seattle, WA, USA; Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, WA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S23524642183030
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http://dx.doi.org/10.1016/S2352-4642(18)30306-7DOI Listing
January 2019

Inflammation Markers in Type 2 Diabetes and the Metabolic Syndrome in the Pediatric Population.

Curr Diab Rep 2018 10 18;18(12):131. Epub 2018 Oct 18.

Center for Integrative Brain Research, Seattle Children's Research Institute, 1900 Ninth Avenue, Seattle, WA, 98101, USA.

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http://link.springer.com/10.1007/s11892-018-1110-5
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http://dx.doi.org/10.1007/s11892-018-1110-5DOI Listing
October 2018

Simultaneous F18-FDG-PET/MR Optimized Treatment Planning in a Young Patient with Sacro-Coccygeal Chordoma.

Klin Padiatr 2018 Oct 1;230(6):326-327. Epub 2018 Oct 1.

Department of Nuclear Medicine, University Hospital of Leipzig, Leipzig.

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http://dx.doi.org/10.1055/a-0715-1768DOI Listing
October 2018

Consuming glucose-sweetened, not fructose-sweetened, beverages increases fasting insulin in healthy humans.

Eur J Clin Nutr 2019 03 30;73(3):487-490. Epub 2018 Aug 30.

Cancer Prevention Program, Division of Public Health Sciences and Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41430-018-0297-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395516PMC
March 2019

Gas exchange mechanisms in preterm infants on HFOV - a computational approach.

Sci Rep 2018 08 29;8(1):13008. Epub 2018 Aug 29.

Division of Neonatology, Dr. von Hauner Children's Hospital, Perinatal Center Grosshadern, LMU-Munich, 81337, Munich, Germany.

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http://www.nature.com/articles/s41598-018-30830-x
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http://dx.doi.org/10.1038/s41598-018-30830-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115430PMC
August 2018

Multimodal imaging findings during severe attacks of familial hemiplegic migraine type 2.

J Neurol Sci 2018 09 26;392:22-27. Epub 2018 Jun 26.

Centre of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen, Germany.

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http://dx.doi.org/10.1016/j.jns.2018.06.019DOI Listing
September 2018

Changes in Satiety Hormones in Response to Leptin Treatment in a Patient with Leptin Deficiency.

Horm Res Paediatr 2018 11;90(6):424-430. Epub 2018 Jul 11.

Division of Pediatric Endocrinology, Diabetes and Obesity Unit, Department of Pediatrics and Adolescent Medicine, Ulm University, Ulm, Germany.

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http://dx.doi.org/10.1159/000489884DOI Listing
August 2019

The BaMM web server for de-novo motif discovery and regulatory sequence analysis.

Nucleic Acids Res 2018 07;46(W1):W215-W220

Quantitative and Computational Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1093/nar/gky431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030882PMC
July 2018

Structural insight into industrially relevant glucoamylases: flexible positions of starch-binding domains.

Acta Crystallogr D Struct Biol 2018 05 26;74(Pt 5):463-470. Epub 2018 Apr 26.

Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5DD, England.

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http://dx.doi.org/10.1107/S2059798318004989DOI Listing
May 2018

Publisher Correction: Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors.

Sci Rep 2018 Apr 13;8(1):6192. Epub 2018 Apr 13.

Department of Medicine, State University of New York (SUNY) Upstate Medical University, 505 Irving Avenue, Syracuse, NY, 13210, USA.

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http://dx.doi.org/10.1038/s41598-018-24359-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899092PMC
April 2018

Do we need gadolinium-based contrast medium for brain magnetic resonance imaging in children?

Pediatr Radiol 2018 06 6;48(6):858-864. Epub 2018 Apr 6.

Department of Paediatric Radiology, University Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00247-017-3999-2DOI Listing
June 2018

Chimeric peptide EP45 as a dual agonist at GLP-1 and NPY2R receptors.

Sci Rep 2018 02 28;8(1):3749. Epub 2018 Feb 28.

Department of Medicine, State University of New York (SUNY) Upstate Medical University, 505 Irving Avenue, Syracuse, NY, 13210, USA.

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http://dx.doi.org/10.1038/s41598-018-22106-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830615PMC
February 2018

Rising Obesity in Children: A Serious Public Health Concern.

Indian J Pediatr 2018 06 17;85(6):461-462. Epub 2018 Feb 17.

Division of Pediatric Endocrinology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.

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http://dx.doi.org/10.1007/s12098-018-2639-7DOI Listing
June 2018

Improving the Care of Youth With Type 1 Diabetes With a Novel Medical-Legal Community Intervention: The Diabetes Community Care Ambassador Program.

Diabetes Educ 2018 04 11;44(2):168-177. Epub 2018 Jan 11.

Division of Endocrinology & Diabetes, Department of Pediatrics, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1177/0145721717750346DOI Listing
April 2018

Assessment of disturbed glucose metabolism and surrogate measures of insulin sensitivity in obese children and adolescents.

Nutr Diabetes 2017 Dec 14;7(12):301. Epub 2017 Dec 14.

Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, WA, 98109, USA.

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http://www.nature.com/articles/s41387-017-0004-y
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http://dx.doi.org/10.1038/s41387-017-0004-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865547PMC
December 2017

Oxytocin and Naltrexone Successfully Treat Hypothalamic Obesity in a Boy Post-Craniopharyngioma Resection.

J Clin Endocrinol Metab 2018 02;103(2):370-375

Center for Integrative Brain Research, Seattle Children's Hospital and Research Institute, Seattle, Washington.

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http://dx.doi.org/10.1210/jc.2017-02080DOI Listing
February 2018

Genetic and Syndromic Causes of Obesity and its Management.

Indian J Pediatr 2018 Jun 27;85(6):478-485. Epub 2017 Nov 27.

Division of Endocrinology and Diabetes, Department of Pediatrics, Seattle Children's Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA, 98105, USA.

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http://dx.doi.org/10.1007/s12098-017-2502-2DOI Listing
June 2018

Probiotic strains and mechanistic insights for the treatment of type 2 diabetes.

Endocrine 2017 Nov 19;58(2):207-227. Epub 2017 Oct 19.

Center for Integrative Brain Research, Seattle Children's Hospital & Research Institute, Seattle, WA, 98101, USA.

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http://link.springer.com/10.1007/s12020-017-1433-z
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http://dx.doi.org/10.1007/s12020-017-1433-zDOI Listing
November 2017

Associations between Liver Enzyme Levels and Parameters of the Metabolic Syndrome in Obese Children.

Horm Res Paediatr 2017 12;88(3-4):265-273. Epub 2017 Sep 12.

Center for Integrative Brain Research, Seattle Children's Hospital and Research Institute, Seattle, Washington, USA.

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http://dx.doi.org/10.1159/000479868DOI Listing
June 2018

Cerebral Fat Embolism: Clinical Presentation, Diagnostic Steps and Long-Term Follow-Up.

Eur Neurol 2017 12;78(3-4):181-187. Epub 2017 Sep 12.

Department of Neurology, Klinikum Kassel, Kassel, Germany.

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http://dx.doi.org/10.1159/000479002DOI Listing
May 2018

Just a Gut Feeling: Central Nervous Effects of Peripheral Gastrointestinal Hormones.

Endocr Dev 2017 15;32:100-123. Epub 2017 Aug 15.

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http://dx.doi.org/10.1159/000475734DOI Listing
February 2018

A simplified parametrised model for lung microstructures capable of mimicking realistic geometrical and mechanical properties.

Comput Biol Med 2017 10 1;89:104-114. Epub 2017 Aug 1.

Institute for Computational Mechanics, Technical University of Munich, Boltzmannstrasse 15, 85748, Garching b. München, Germany.

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http://dx.doi.org/10.1016/j.compbiomed.2017.07.017DOI Listing
October 2017

I can hear my shunt-audible noises associated with CSF shunts in hydrocephalic patients.

Acta Neurochir (Wien) 2017 06 14;159(6):981-986. Epub 2017 Apr 14.

Kassel School of Medicine, Universitiy of Southampton, Southampton, UK.

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http://dx.doi.org/10.1007/s00701-017-3179-zDOI Listing
June 2017

Structural and functional insight into human O-GlcNAcase.

Nat Chem Biol 2017 06 27;13(6):610-612. Epub 2017 Mar 27.

York Structural Biology Laboratory, Department of Chemistry University of York, York, UK.

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http://www.nature.com/articles/nchembio.2358
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http://dx.doi.org/10.1038/nchembio.2358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438047PMC
June 2017

Effect of Weight Loss on Puberty Onset in Overweight Children.

J Pediatr 2017 05 24;184:143-150.e1. Epub 2017 Feb 24.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA; Division of Endocrinology, Department of Pediatrics, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1016/j.jpeds.2017.01.066DOI Listing
May 2017

Amylose recognition and ring-size determination of amylomaltase.

Sci Adv 2017 Jan 13;3(1):e1601386. Epub 2017 Jan 13.

Institut für Bioanalytische Chemie, Universität Leipzig, Deutscher Platz 5, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1126/sciadv.1601386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235332PMC
January 2017

Different origins of hydrocephalus lead to different shunt revision rates.

Neurol Neurochir Pol 2017 Jan - Feb;51(1):72-76. Epub 2016 Nov 30.

Department of Neurosurgery, Klinikum Kassel, Kassel, Germany.

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http://dx.doi.org/10.1016/j.pjnns.2016.11.007DOI Listing
June 2017

Coupling of EIT with computational lung modeling for predicting patient-specific ventilatory responses.

J Appl Physiol (1985) 2017 Apr 8;122(4):855-867. Epub 2016 Dec 8.

Institute for Computational Mechanics, Technical University of Munich, Munich, Germany; and

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http://dx.doi.org/10.1152/japplphysiol.00236.2016DOI Listing
April 2017

Leg Muscle Involvement in Facioscapulohumeral Muscular Dystrophy: Comparison between Facioscapulohumeral Muscular Dystrophy Types 1 and 2.

Eur Neurol 2017 18;77(1-2):32-39. Epub 2016 Nov 18.

Department of Neurology, Klinikum Kassel - University Hospital of the University of Southampton, Kassel, Germany.

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http://dx.doi.org/10.1159/000452763DOI Listing
September 2017

Robust Reductions of Excess Weight and Hyperphagia by Beloranib in Rat Models of Genetic and Hypothalamic Obesity.

Endocrinology 2017 01;158(1):41-55

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington 98101; and.

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https://academic.oup.com/endo/article/158/1/41/2751120
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http://dx.doi.org/10.1210/en.2016-1665DOI Listing
January 2017

Evaluation of occurring complications after flow diverter treatment of elastase-induced aneurysm in rabbits using micro-CT and MRI at 9.4 T.

Neuroradiology 2016 Oct 25;58(10):987-996. Epub 2016 Jul 25.

Department of Neuroradiology, Saarland University Hospital, Kirrbergerstraße1, 66424, Homburg, Saar, Germany.

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http://dx.doi.org/10.1007/s00234-016-1730-xDOI Listing
October 2016

Activation of nuclear factor kappa B pathway and reduction of hypothalamic oxytocin following hypothalamic lesions.

J Syst Integr Neurosci 2016 Feb 29;2(1):79-84. Epub 2016 Jan 29.

Center for Integrative Brain Research, Seattle Children's Research Institute, USA.

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http://dx.doi.org/10.15761/JSIN.1000114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976786PMC
February 2016

Impact of External Ventricular Drainage Volumes on Shunt Dependency after Subarachnoid Hemorrhage.

J Neurol Surg A Cent Eur Neurosurg 2017 May 22;78(3):227-230. Epub 2016 Jul 22.

Department of Neurology, Klinikum Kassel, Kassel, Germany.

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http://dx.doi.org/10.1055/s-0036-1584813DOI Listing
May 2017

Betatrophin: no relation to glucose metabolism or weight status in obese children before and after lifestyle intervention.

Pediatr Diabetes 2017 Sep 12;18(6):485-491. Epub 2016 Jul 12.

Department of Pediatric Endocrinology, Diabetes and Nutrition Medicine, Vestische Hospital for Children and Adolescents Datteln, University of Witten/Herdecke, Witten, Germany.

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http://doi.wiley.com/10.1111/pedi.12412
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http://dx.doi.org/10.1111/pedi.12412DOI Listing
September 2017

No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial.

Am J Clin Nutr 2016 Aug 29;104(2):306-14. Epub 2016 Jun 29.

Cancer Prevention Program, Division of Public Health Sciences, and Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, and Departments of Epidemiology and

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http://dx.doi.org/10.3945/ajcn.115.129650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962158PMC
August 2016

Fluid-structure interaction including volumetric coupling with homogenised subdomains for modeling respiratory mechanics.

Int J Numer Method Biomed Eng 2017 04 8;33(4). Epub 2016 Jul 8.

Institute for Computational Mechanics, Technische Universität München, Boltzmannstrasse 15, D-85748 Garching b. München, Germany.

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http://dx.doi.org/10.1002/cnm.2812DOI Listing
April 2017

Efficient solvers for coupled models in respiratory mechanics.

Int J Numer Method Biomed Eng 2017 02 25;33(2). Epub 2016 May 25.

Institute for Computational Mechanics, Technische Universität München, Garching, D-85747, Germany.

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http://dx.doi.org/10.1002/cnm.2795DOI Listing
February 2017

Solution Structure and Constrained Molecular Dynamics Study of Vitamin B12 Conjugates of the Anorectic Peptide PYY(3-36).

ChemMedChem 2016 05 30;11(9):1015-21. Epub 2016 Mar 30.

Department of Chemistry, Center for Science and Technology, Syracuse University, 111 College Place, Syracuse, NY, 13244, USA.

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http://dx.doi.org/10.1002/cmdc.201600073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878914PMC
May 2016

A comprehensive computational human lung model incorporating inter-acinar dependencies: Application to spontaneous breathing and mechanical ventilation.

Int J Numer Method Biomed Eng 2017 01 22;33(1). Epub 2016 Jun 22.

Institute for Computational Mechanics, Technische Universität München, D-85747 Garching, Germany.

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http://dx.doi.org/10.1002/cnm.2787DOI Listing
January 2017

Fibroblast growth factor 21 (FGF-21) in obese children: no relationship to growth, IGF-1, and IGFBP-3.

Horm Mol Biol Clin Investig 2016 Feb 17;30(2). Epub 2016 Feb 17.

.

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http://dx.doi.org/10.1515/hmbci-2015-0074DOI Listing
February 2016

Thomsen myotonia--A 4-generation family with a new mutation and a mild phenotype.

Muscle Nerve 2016 Apr 29;53(4):653-4. Epub 2015 Dec 29.

Department of Neurology Klinikum Kassel, Kassel, Germany.

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http://dx.doi.org/10.1002/mus.24971DOI Listing
April 2016

Urinary Output Predicts Survival in Patients Undergoing Extracorporeal Membrane Oxygenation Following Cardiovascular Surgery.

Crit Care Med 2016 Mar;44(3):531-8

1Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.2Department of Cardiac Surgery, Paracelsus Medical University Salzburg, Salzburg, Austria.3Department of Cardiac Surgery, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.4Department of Anaesthesia and Intensive Care Medicine, Karl Landsteiner University of Health Sciences, University Hospital Krems, Krems an der Donau, Austria.5Department of Cardiotharacic and Vascular Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/CCM.0000000000001421DOI Listing
March 2016

A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors.

Angew Chem Int Ed Engl 2015 Dec 6;54(51):15429-33. Epub 2015 Nov 6.

Department of Chemistry, Simon Fraser University, Burnaby, British Columbia (Canada).

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http://dx.doi.org/10.1002/anie.201507985DOI Listing
December 2015

No difference in ad libitum energy intake in healthy men and women consuming beverages sweetened with fructose, glucose, or high-fructose corn syrup: a randomized trial.

Am J Clin Nutr 2015 Dec 4;102(6):1373-80. Epub 2015 Nov 4.

Cancer Prevention Program, Division of Public Health Sciences and Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, Department of Epidemiology,

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http://dx.doi.org/10.3945/ajcn.115.116368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658464PMC
December 2015

Hypothalamic Obesity in Craniopharyngioma Patients: Disturbed Energy Homeostasis Related to Extent of Hypothalamic Damage and Its Implication for Obesity Intervention.

Authors:
Christian L Roth

J Clin Med 2015 Sep 9;4(9):1774-97. Epub 2015 Sep 9.

Seattle Children's Hospital Research Institute, University of Washington, Department of Pediatrics, Center for Integrative Brain Research, 1900 Ninth Ave, P.O. Box 5371 M/S-C9S, Seattle, WA 98101, USA.

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http://dx.doi.org/10.3390/jcm4091774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600159PMC
September 2015

Loss of function mutations in HARS cause a spectrum of inherited peripheral neuropathies.

Brain 2015 Aug 13;138(Pt 8):2161-72. Epub 2015 Jun 13.

2 Neurogenetics Group, VIB-Department of Molecular Genetics, University of Antwerp, Antwerpen 2610, Belgium 3 Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerpen 2610, Belgium 16 Department of Neurology, Antwerp University Hospital, Antwerpen 2610, Belgium.

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http://dx.doi.org/10.1093/brain/awv158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840952PMC
August 2015

Pediatric Central Diabetes Insipidus: Brain Malformations Are Common and Few Patients Have Idiopathic Disease.

J Clin Endocrinol Metab 2015 Aug 1;100(8):3074-80. Epub 2015 Jun 1.

Division of Endocrinology and Diabetes (D.W., C.P., C.L.R.), Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington 98105; Center for Integrative Brain Research (C.E., C.L.R.), Seattle Children's Hospital, Seattle, Washington 98101; Department of Pediatric Endocrinology, Seattle Children's Hospital and Research Institute, and Department of Radiology (F.A.P.), Seattle Children's Hospital, University of Washington, Seattle, Washington 98105.

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http://dx.doi.org/10.1210/jc.2015-1287DOI Listing
August 2015

Correlation between alveolar ventilation and electrical properties of lung parenchyma.

Physiol Meas 2015 Jun 26;36(6):1211-26. Epub 2015 May 26.

Institute for Computational Mechanics, Technische Universität München, Boltzmannstrasse 15, D-85748 Garching b. München, Germany.

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http://dx.doi.org/10.1088/0967-3334/36/6/1211DOI Listing
June 2015

Obesity management in Prader-Willi syndrome.

Pediatr Endocrinol Rev 2015 Mar;12(3):297-307

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March 2015