Christian Reichel

Christian Reichel

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Christian Reichel

Christian Reichel

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SARCOSYL-PAGE: Optimized Protocols for the Separation and Immunological Detection of PEGylated Proteins.

Methods Mol Biol 2019 ;1855:131-149

Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.

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http://link.springer.com/10.1007/978-1-4939-8793-1_14
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http://dx.doi.org/10.1007/978-1-4939-8793-1_14DOI Listing
June 2019

Updated protocols for the detection of Sotatercept and Luspatercept in human serum.

Drug Test Anal 2018 Nov 1;10(11-12):1708-1713. Epub 2018 Oct 1.

European Monitoring Center for Emerging Doping Agents, German Sport University Cologne, Am Sportpark Muengersdorf 6, 50933, Cologne, Germany.

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http://doi.wiley.com/10.1002/dta.2500
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http://dx.doi.org/10.1002/dta.2500DOI Listing
November 2018

Combined detection of the ActRII-Fc fusion proteins Sotatercept (ActRIIA-Fc) and Luspatercept (modified ActRIIB-Fc) in serum by means of immunoaffinity purification, tryptic digestion, and LC-MS/MS.

Drug Test Anal 2018 Nov 30;10(11-12):1714-1721. Epub 2018 Oct 30.

Center for Preventive Doping Research/Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.

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http://doi.wiley.com/10.1002/dta.2513
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http://dx.doi.org/10.1002/dta.2513DOI Listing
November 2018

Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting.

Drug Test Anal 2018 Jun 27;10(6):927-937. Epub 2017 Dec 27.

Institute of Biochemistry/Centre for Preventive Doping Research, German Sport University Cologne, Germany.

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http://dx.doi.org/10.1002/dta.2346DOI Listing
June 2018

Antibody-based strategies for the detection of Luspatercept (ACE-536) in human serum.

Drug Test Anal 2017 Nov 9;9(11-12):1721-1730. Epub 2017 Nov 9.

Institute of Biochemistry / Center for Preventive Doping Research, German Sport University Cologne, Am Sportpark Muengersdorf 6, 50933, Cologne, Germany.

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http://dx.doi.org/10.1002/dta.2302DOI Listing
November 2017

Evaluation of AMGEN clone 9G8A anti-Epo antibody for application in doping control.

Drug Test Anal 2016 Nov 21;8(11-12):1131-1137. Epub 2016 Sep 21.

Institute of Biochemistry / Center for Preventive Doping Research, German Sport University Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/dta.2057DOI Listing
November 2016

Testing for the erythropoiesis-stimulating agent Sotatercept/ACE-011 (ActRIIA-Fc) in serum by means of Western blotting and LC-HRMS.

Drug Test Anal 2016 Nov 13;8(11-12):1152-1161. Epub 2016 Oct 13.

Center for Preventive Doping Research/Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/dta.2093DOI Listing
November 2016

Optimizing SAR-PAGE.

Drug Test Anal 2015 Nov-Dec;7(11-12):1014-6. Epub 2015 Nov 26.

Institute of Biochemistry, German Sports University, Germany.

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http://dx.doi.org/10.1002/dta.1915DOI Listing
September 2016

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate.

Hypertension 2015 Aug 1;66(2):422-9. Epub 2015 Jun 1.

From the Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom (C.M., M.M., M.P., T.D.S., A.M.V.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom (D.G., N.H.J.A., S.M.A., M.M.B., A.F.D., S.P.); Institute of Bioinformatics and Systems Biology, Helmholtz Zentrum München, Germany (G.K., K.S.); Faculty of Medicine, University of Southampton, Southampton, United Kingdom (P.T., M.H.E., C.C.); Wellcome Trust Sanger Institute Human Genetics, Hinxton, United Kingdom (S.-Y.S., N.S.); MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom (S.-Y.S.); Chemical Analytics, Seibersdorf Labor GmbH, Seibersdorf, Austria (T.G., A.H., C.R.); Institute of Epidemiology II, Helmholtz Zentrum München, Germany (A.P., C.G.); Research Unit Molecular Epidemiology, Helmholtz Zentrum München, Germany (A.P., R.W.-S., T.X.); Cardiovascular and Metabolic Diseases, Pfizer Worldwide Research and Development, Cambridge, MA (M.J.B.); Edison Pharmaceuticals, Mountain View, CA (J.T.); Metabolon, Inc, Durham, NC (R.P.M.); Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom (C.C.); Scottish Pulmonary Vascular Unit, Golden jubilee Hospital, Glasgow, United Kingdom (A.C.C.); Department of Physiology and Biophysics, Weill Cornell Medical College in Qatar, Education City, Qatar Foundation, Doha, Qatar (K.S.); and Academic Rheumatology, University of Nottingham, Nottingham, United Kingdom (A.M.V.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490909PMC
August 2015

Axl activates autocrine transforming growth factor-β signaling in hepatocellular carcinoma.

Hepatology 2015 Mar 28;61(3):930-41. Epub 2015 Jan 28.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/hep.27492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450343PMC
March 2015

Isolation, enrichment, and analysis of erythropoietins in anti-doping analysis by receptor-coated magnetic beads and liquid chromatography-mass spectrometry.

Anal Chem 2014 Dec 5;86(24):12014-21. Epub 2014 Dec 5.

Center for Preventive Doping Research/Institute of Biochemistry, German Sport University Cologne , Am Sportpark Müngersdorf 6, 50933 Cologne, Germany.

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http://dx.doi.org/10.1021/ac5024765DOI Listing
December 2014

Differences in sialic acid O-acetylation between human urinary and recombinant erythropoietins: a possible mass spectrometric marker for doping control.

Drug Test Anal 2013 Nov-Dec;5(11-12):877-89. Epub 2013 Nov 6.

Doping Control Laboratory, AIT Seibersdorf Laboratories, A-2444, Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.1563DOI Listing
August 2014

Detection of peptidic erythropoiesis-stimulating agents in sport.

Br J Sports Med 2014 May 27;48(10):842-7. Epub 2014 Mar 27.

Doping Control Laboratory, AIT Seibersdorf Labor GmbH, , Seibersdorf, Austria.

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http://dx.doi.org/10.1136/bjsports-2014-093555DOI Listing
May 2014

Gel electrophoretic methods for the analysis of biosimilar pharmaceuticals using the example of recombinant erythropoietin.

Bioanalysis 2013 Mar;5(5):587-602

Doping Control Laboratory, AIT Seibersdorf Laboratories, Mendelstrasse 4, 2444 Seibersdorf, Austria.

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http://dx.doi.org/10.4155/bio.13.9DOI Listing
March 2013

Detection of EPO-Fc fusion protein in human blood: screening and confirmation protocols for sports drug testing.

Drug Test Anal 2012 Nov 5;4(11):818-29. Epub 2012 Jul 5.

Doping Control Laboratory, AIT Seibersdorf Laboratories, A-2444 Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.1381DOI Listing
November 2012

Sports drug testing for erythropoiesis-stimulating agents and autologous blood transfusion.

Drug Test Anal 2012 Nov 23;4(11):803-4. Epub 2012 Aug 23.

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http://doi.wiley.com/10.1002/dta.1405
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http://dx.doi.org/10.1002/dta.1405DOI Listing
November 2012

Mass spectrometric analysis of EPO IEF-PAGE interfering substances in nitrile examination gloves.

Drug Test Anal 2012 Oct 18;4(10):761-74. Epub 2012 Oct 18.

Doping Control Laboratory, AIT Seibersdorf Laboratories, A-2444, Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.1424DOI Listing
October 2012

SARCOSYL-PAGE: a new electrophoretic method for the separation and immunological detection of PEGylated proteins.

Methods Mol Biol 2012 ;869:65-79

AIT Seibersdorf Laboratories, Seibersdorf, Austria.

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http://dx.doi.org/10.1007/978-1-61779-821-4_7DOI Listing
September 2012

Application of high-throughput IEF-PAGE for EPO-doping testing.

Drug Test Anal 2012 Sep 19;4(9):728-32. Epub 2012 Sep 19.

Doping Control Laboratory, AIT Seibersdorf Laboratories, A-2444 Seibersdorf, Austria.

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http://doi.wiley.com/10.1002/dta.1411
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http://dx.doi.org/10.1002/dta.1411DOI Listing
September 2012

Detection of erythropoiesis-stimulating agents in human anti-doping control: past, present and future.

Bioanalysis 2012 Jul;4(13):1565-75

Swiss Laboratory for Doping Analyses, University Center of Legal Medicine, Centre Hospitalier Universitaire Vaudois & University of Lausanne, Geneva & Lausanne, Switzerland.

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http://dx.doi.org/10.4155/bio.12.153DOI Listing
July 2012

a membrane device for substrate-free photovoltaic characterization of quantum dot based p-i-n solar cells.

Adv Mater 2012 Jun 16;24(23):3124-9. Epub 2012 May 16.

Fraunhofer Institute for Solar Energy Systems, Heidenhofstrasse 2, Freibur 79110, Germany.

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http://dx.doi.org/10.1002/adma.201200539DOI Listing
June 2012

The overlooked difference between human endogenous and recombinant erythropoietins and its implication for sports drug testing and pharmaceutical drug design.

Drug Test Anal 2011 Nov-Dec;3(11-12):883-91. Epub 2011 Dec 2.

Doping Control Laboratory, AIT Seibersdorf Laboratories, A-2444 Seibersdorf, Austria.

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http://doi.wiley.com/10.1002/dta.388
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http://dx.doi.org/10.1002/dta.388DOI Listing
May 2012

OMICS-strategies and methods in the fight against doping.

Forensic Sci Int 2011 Dec 20;213(1-3):20-34. Epub 2011 Aug 20.

Doping Control Laboratory, AIT Seibersdorf Laboratories, A-2444 Seibersdorf, Austria.

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http://dx.doi.org/10.1016/j.forsciint.2011.07.031DOI Listing
December 2011

Recent developments in doping testing for erythropoietin.

Anal Bioanal Chem 2011 Aug 3;401(2):463-81. Epub 2011 Jun 3.

Doping Control Laboratory, AIT Seibersdorf Laboratories, Seibersdorf, Austria.

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http://dx.doi.org/10.1007/s00216-011-5116-yDOI Listing
August 2011

Defending Dynepo detection.

Drug Test Anal 2010 Nov-Dec;2(11-12):526-32. Epub 2010 Dec 1.

Doping Control Laboratory, Seibersdorf Labor GmbH, Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.230DOI Listing
May 2011

The interference of heparin on IEF-PAGE of erythropoietins.

Drug Test Anal 2010 Nov-Dec;2(11-12):568-75. Epub 2010 Nov 11.

Doping Control Laboratory, AIT Seibersdorf Laboratories, Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.182DOI Listing
May 2011

Practicing IEF-PAGE of EPO: the impact of detergents and sample application methods on analytical performance in doping control.

Drug Test Anal 2010 Nov-Dec;2(11-12):603-19

Doping Control Laboratory, AIT Seibersdorf Laboratories, Seibersdorf, Austria.

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http://doi.wiley.com/10.1002/dta.215
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http://dx.doi.org/10.1002/dta.215DOI Listing
May 2011

Cathelicidin LL-37, granzymes, TGF-beta1 and cytokines levels in induced sputum from farmers with and without COPD.

Ann Agric Environ Med 2009 ;16(2):289-97

Unit of Fibroproliferative Diseases, Institute of Agricultural Medicine, Jaczewskiego 2, 20-950 Lublin, Poland.

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March 2010

Erythropoietin and analogs.

Handb Exp Pharmacol 2010 (195):251-94

Austrian Research Centers GmbH - ARC, Doping Control Laboratory, A-2444, Seibersdorf, Austria.

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http://dx.doi.org/10.1007/978-3-540-79088-4_12DOI Listing
February 2010

SARCOSYL-PAGE: a new method for the detection of MIRCERA- and EPO-doping in blood.

Drug Test Anal 2009 Nov;1(11-12):494-504

Doping Control Laboratory, AIT Seibersdorf Laboratories, Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.97DOI Listing
November 2009

Comparing standard and microwave assisted staining protocols for SDS-PAGE of glycoproteins followed by subsequent PMF with MALDI MS.

J Proteomics 2009 May 29;72(4):628-39. Epub 2008 Dec 29.

Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, Vienna, Austria.

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http://dx.doi.org/10.1016/j.jprot.2008.12.005DOI Listing
May 2009

SDS-PAGE of recombinant and endogenous erythropoietins: benefits and limitations of the method for application in doping control.

Drug Test Anal 2009 Jan;1(1):43-50

Doping Control Laboratory, Austrian Research Centers GmbH-ARC, A-2444 Seibersdorf, Austria.

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http://dx.doi.org/10.1002/dta.10DOI Listing
January 2009

Synthesis and identification of hydroxylated metabolites of the anti-estrogenic agent cyclofenil.

J Mass Spectrom 2008 Jul;43(7):958-64

Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria.

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http://dx.doi.org/10.1002/jms.1462DOI Listing
July 2008

Identification of zinc-alpha-2-glycoprotein binding to clone AE7A5 antihuman EPO antibody by means of nano-HPLC and high-resolution high-mass accuracy ESI-MS/MS.

J Mass Spectrom 2008 Jul;43(7):916-23

Doping Control Laboratory, Austrian Research Centers GmbH-ARC, A-2444 Seibersdorf, Austria.

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http://dx.doi.org/10.1002/jms.1444DOI Listing
July 2008

Characterisation of intact recombinant human erythropoietins applied in doping by means of planar gel electrophoretic techniques and matrix-assisted laser desorption/ionisation linear time-of-flight mass spectrometry.

Rapid Commun Mass Spectrom 2005 ;19(5):728-42

Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, A-1060 Vienna, Austria.

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http://dx.doi.org/10.1002/rcm.1830DOI Listing
May 2005

Detection of isoforms of recombinant human erythropoietin by various plant lectins after isoelectric focusing.

Electrophoresis 2005 May;26(9):1633-45

Doping Control Laboratory, ARC Seibersdorf Research GmbH, A-244 Seibersdorf, Austria.

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http://dx.doi.org/10.1002/elps.200410214DOI Listing
May 2005