Christian Recher

Christian Recher

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Gilteritinib or Chemotherapy for Relapsed or Refractory -Mutated AML.

N Engl J Med 2019 10;381(18):1728-1740

From the Abramson Cancer Center, University of Pennsylvania (A.E.P.), and Thomas Jefferson University (M.K.) - both in Philadelphia; Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), Meldola (G.M.), L. and A. Seràgnoli Institute of Hematology, Bologna University Medical School, Bologna (S.P.), Ospedali Riuniti Villa Sofia-Cervello, Palermo (F.F.), and IRCCS San Raffaele Scientific Institute, Milan (F.C.) - all in Italy; University of Texas M.D. Anderson Cancer Center, Houston (J.E.C.); Universitätsklinikum Giessen und Marburg, Marburg, Germany (A.N.); Memorial Sloan Kettering Cancer Center, New York (E. Berman); Hospital Universitari i Politècnic La Fe, Valencia, and Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Instituto Carlos III, Madrid - both in Spain (P.M.); University of Maryland Greenebaum Comprehensive Cancer Center (M.R.B.) and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University (M.J.L.) - both in Baltimore; University of Chicago, Chicago (R.A.L.), and Astellas Pharma, Northbrook (C.L., N. Hasabou, X.L., E. Bahceci) - both in Illinois; University of Minnesota, Minneapolis (C.U.); University of Alabama at Birmingham, Birmingham (H.P.E., A.D.S.); Hollings Cancer Center, Medical University of South Carolina, Charleston (R.S.); University of California, San Francisco, San Francisco (R.O.); National Taiwan University, Taipei City, Taiwan (W.-C.C.); Yale University School of Medicine, New Haven, CT (N.P.); Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Université Toulouse III Paul Sabatier, Toulouse, France (C.R.); Sendai Medical Center, National Hospital Organization, Sendai (H.Y.), and University of Fukui, Fukui (N. Hosono) - both in Japan; Seoul National University (S.-S.Y.) and Asan Medical Center, University of Ulsan College of Medicine (J.-H.L.) - both in Seoul, South Korea; Wake Forest Baptist Medical Center, Winston-Salem, NC (T.P.); and Massachusetts General Hospital, Harvard Medical School, Boston (A.T.F.).

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http://dx.doi.org/10.1056/NEJMoa1902688DOI Listing
October 2019

Are social inequalities in acute myeloid leukemia survival explained by differences in treatment utilization? Results from a French longitudinal observational study among older patients.

BMC Cancer 2019 Sep 5;19(1):883. Epub 2019 Sep 5.

LEASP, UMR 1027, Equipe labellisée Ligue Nationale Contre le Cancer, Faculté de médecine de Purpan, Inserm-Université Toulouse III Paul Sabatier, 37 allées Jules Guesde, 31000, Toulouse, France.

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http://dx.doi.org/10.1186/s12885-019-6093-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729078PMC
September 2019

Outcome of patients aged 60-75 years with newly diagnosed secondary acute myeloid leukemia: A single-institution experience.

Cancer Med 2019 Jul 7;8(8):3846-3854. Epub 2019 Jun 7.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1002/cam4.2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639188PMC
July 2019

Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia.

Oncogenesis 2019 Jul 16;8(8):39. Epub 2019 Jul 16.

Cancer Research Center of Toulouse (CRCT), UMR1037 INSERM, ERL5294 CNRS, Equipe Labellisée LIGUE, Toulouse, France.

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http://dx.doi.org/10.1038/s41389-019-0148-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635375PMC
July 2019

Outcome of AML patients with IDH2 mutations in real world before the era of IDH2 inhibitors.

Leuk Res 2019 Jun 27;81:82-87. Epub 2019 Apr 27.

Université Toulouse III Paul Sabatier, Toulouse, France; Cancer Research Center of Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.04.010DOI Listing
June 2019

FLT3-TKD Mutations Associated With NPM1 Mutations Define a Favorable-risk Group in Patients With Acute Myeloid Leukemia.

Clin Lymphoma Myeloma Leuk 2018 12 13;18(12):e545-e550. Epub 2018 Jun 13.

Department of Hematology, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite, France; Faculté de Médecine Lyon-Sud Charles Mérieux, Université Claude Bernard Lyon I, Pierre Bénite, France; LBMC, ENS, CNRS UMR5239, Faculté de Médecine Lyon-Sud, Pierre Bénite, France. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2018.06.006DOI Listing
December 2018

Hydroxyurea prior to intensive chemotherapy in AML with moderate leukocytosis.

Leuk Res 2018 12 31;75:7-10. Epub 2018 Oct 31.

Service d'Hématologie, CHU de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France; Université Toulouse III Paul Sabatier, Toulouse, France; Cancer Research Center of Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01452126183045
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http://dx.doi.org/10.1016/j.leukres.2018.10.015DOI Listing
December 2018

Improved Survival by Adding Lomustine to Conventional Chemotherapy for Elderly Patients With AML Without Unfavorable Cytogenetics: Results of the LAM-SA 2007 FILO Trial.

J Clin Oncol 2018 Sep 27:JCO2018787366. Epub 2018 Sep 27.

Arnaud Pigneux and Pierre-Yves Dumas, Bordeaux University Hospital, Bordeaux University, INSERM 1035; Louis-Rachid Salmi, Ariane Mineur, and Julien Asselineau, Bordeaux University Hospital, Bordeaux; Marie C. Béné, and Jacques Delaunay, Nantes University Hospital, Nantes; Caroline Bonmati, Nancy University Hospital, Nancy; Romain Guièze, Clermont-Ferrand University Hospital, Clermont Ferrand; Isabelle Luquet, Eric Delabesse, and Christian Récher, Toulouse University Hospital, Toulouse; Pascale Cornillet-Lefebvre, Reims University Hospital, Reims; Jean-Christophe Ianotto, Brest University Hospital, Brest; Mario Ojeda-Uribe, Mulhouse Regional Hospital, Mulhouse; Mathilde Hunault and Norbert Ifrah, Angers University Hospital and INSERM U 892/CNRS 6299, Angers; Anne Banos, Cote Basque General Hospital, Bayonne; Luc Matthieu Fornecker, Strasbourg University Hospital, Strasbourg; Marc Bernard, Rennes University Hospital, Rennes; Eric Jourdan, Nîmes University Hospital, Nîmes; Norbert Vey, Institut Paoli Calmettes, Marseilles; Hacene Zerazhi, Avignon General Hospital, Avignon; Yosr Hishri, Montpellier University Hospital, Montpellier; Roselyne Delepine, Tours University Hospital, Tours; and Jean-Yves Cahn, Grenoble University Hospital, Grenoble, France.

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http://dx.doi.org/10.1200/JCO.2018.78.7366DOI Listing
September 2018

Risk of Hematologic Malignancies After Radioactive Iodine Treatment of Thyroid Cancer: An Unjustified Warning.

J Clin Oncol 2018 06 3;36(18):1881-1882. Epub 2018 May 3.

Elif Hindié, Bordeaux University Hospitals, Hôpital Haut-Lévêque, Pessac, France; Christian Récher and Slimane Zerdoud, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France; Laurence Leenhardt, Pitié Salpêtrière University Hospital, Paris, France; and Anca M. Avram, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1200/JCO.2018.78.1096DOI Listing
June 2018

Outcomes for HIV-associated diffuse large B-cell lymphoma in the modern combined antiretroviral therapy era.

AIDS 2017 11;31(18):2493-2501

aUnit of Hematology-Oncology, Centre Hospitalier de Versailles, Le ChesnaybUniversité Versailles Saint Quentin en Yvelines, Université Paris-Saclay, Communauté Paris-Saclay, PariscINSERM U1018, Centre pour la Recherche en Epidémiologie et Santé des Populations (CESP), Equipe 'Générations et Santé' Gustave Roussy, VillejuifdSorbonne Universités, INSERM, UPMC Univ Paris 06, Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS1136), PariseUniversité Paris Sud, Faculté de médecine Paris Sud, Le Kremlin-BicêtrefPathology Unit, AP-HP, Hôpitaux Paris Sud Site Béclère, ClamartgInfectious Diseases Unit, CHU Toulouse, ToulousehInternal Medicine and Infectious Diseases Unit, CHU Bordeaux, INSERM U1219, Université de Bordeaux, BordeauxiInfectious Diseases Unit, AP-HP CHU Saint-Antoine, ParisjHIV Infection Unit, Hôpitaux Universitaires, StrasbourgkU1037, CRCT, University Toulouse III Paul SabatierlDepartment of Hematology, Institut Universitaire du Cancer (IUC), ToulousemDepartment of Hematology, AP-HP, CHU Pitié-Salpétrière, ParisnInternal Medicine Unit, AP-HP, Hôpitaux Paris Sud, Le Kremlin-BicêtreoClinical Immunology Unit, AP-HP, Hôpitaux Paris Sud Site Béclère, ClamartpDepartment of Hematology, AP-HP CHU Saint-Antoine, ParisqDepartment of Hematology, AP-HM, Assistance Publique Hôpitaux de Marseille, MarseillerImmunology Unit, AP-HP, Hôpitaux Paris Sud, Le Kremlin-BicêtresDepartment of Hematology, AP-HP, Hôpital Necker Enfants Malades, ParistHematology Unit, Centre Hospitalier Universitaire-Dijon, DijonuDepartment of Onco-Hematology, Archet Hospital, Nice, France.

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http://dx.doi.org/10.1097/QAD.0000000000001652DOI Listing
November 2017

Improved outcome for AML patients over the years 2000-2014.

Blood Cancer J 2017 11 29;7(12):635. Epub 2017 Nov 29.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1038/s41408-017-0011-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802565PMC
November 2017

Platelet transfusion refractoriness in patients with acute myeloid leukemia treated by intensive chemotherapy.

Leuk Res 2017 10 30;61:62-67. Epub 2017 Aug 30.

Université Toulouse III Paul Sabatier, Toulouse, France; Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France; Centre de Recherches en Cancérologie de Toulouse, UMR1037-INSERM, ERL5294 CNRS, Toulouse, France.

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http://dx.doi.org/10.1016/j.leukres.2017.08.015DOI Listing
October 2017

Targeting ATR/CHK1 pathway in acute myeloid leukemia to overcome chemoresistance.

Mol Cell Oncol 2017 18;4(5):e1289293. Epub 2017 Sep 18.

Equipe Labellisée, La Ligue Contre Le Cancer, Toulouse, France.

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http://dx.doi.org/10.1080/23723556.2017.1289293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644474PMC
September 2017

Phase 1 dose-escalation study of oral abexinostat for the treatment of patients with relapsed/refractory higher-risk myelodysplastic syndromes, acute myeloid leukemia, or acute lymphoblastic leukemia.

Leuk Lymphoma 2017 08 2;58(8):1880-1886. Epub 2016 Dec 2.

h Service d'Hématologie , Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole , Toulouse , France.

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http://dx.doi.org/10.1080/10428194.2016.1263843DOI Listing
August 2017

Bendamustine for relapsed blastic plasmacytoid dendritic cell leukaemia.

Hematol Oncol 2017 Jun 8;35(2):252-255. Epub 2015 Oct 8.

Hematology Department, Institut Universitaire du Cancer Toulouse-Oncopole, Toulouse, France.

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http://dx.doi.org/10.1002/hon.2252DOI Listing
June 2017

Randomized Phase II Study of Clofarabine-Based Consolidation for Younger Adults With Acute Myeloid Leukemia in First Remission.

J Clin Oncol 2017 Apr 21;35(11):1223-1230. Epub 2017 Feb 21.

Xavier Thomas, Lyon-Sud University Hospital, Pierre Bénite; Stéphane de Botton, Gustave-Roussy Cancer Institute, Villejuif; Sylvie Chevret, Emmanuel Raffoux, and Hervé Dombret, Paris Saint-Louis University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), University Paris Diderot; Olivier Hermine, Paris Necker University Hospital, AP-HP, University Paris Descartes; Karine Celli-Lebras, Acute Leukemia French Association Coordination Office, Paris Saint-Louis University Hospital, Paris; Denis Caillot, Dijon University Hospital, Dijon; Emilie Lemasle, Henri-Becquerel Cancer Center, Rouen; Jean-Pierre Marolleau, Amiens University Hospital, Amiens; Céline Berthon, Claude Huriez University Hospital; Claude Preudhomme, University of Lille, Claude Huriez University Hospital, Institut National de la Santé et de la Recherche Médicale UMR-S 1172, Jean-Pierre Aubert Research Institute, Lille; Arnaud Pigneux, Bordeaux Haut-Leveque University Hospital, Pessac; Norbert Vey, Paoli-Calmette Cancer Institute, Marseille; Oumedaly Reman, George-Clémenceau University Hospital, Caen; Marc Simon, Valenciennes Hospital, Valenciennes; Christian Recher, Toulouse Cancer University Institute, Toulouse; Jean-Yves Cahn, Grenoble University Hospital, Grenoble; Sylvie Castaigne and Christine Terré, Versailles University Hospital, Versailles-Saint Quentin University, Le Chesnay; and Norbert Ifrah, Angers University Hospital, Angers, France.

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http://dx.doi.org/10.1200/JCO.2016.70.4551DOI Listing
April 2017

Addition of Androgens Improves Survival in Elderly Patients With Acute Myeloid Leukemia: A GOELAMS Study.

J Clin Oncol 2017 Feb 24;35(4):387-393. Epub 2016 Oct 24.

Arnaud Pigneux and Mathieu Sauvezie, Centre Hospitalier Universitaire (CHU) Bordeaux, Université Bordeaux, Institut National de la Santé et de la Recherche Médicale (INSERM) 1035, Bordeaux; Marie C. Béné and Jean-Luc Harousseau, Hôpital Hôtel Dieu, Nantes; Philippe Guardiola, Mathilde Hunault, and Norbert Ifrah, CHU Angers, UMR INSERM U892/CNRS 6299; Jean-Francois Hamel, Université Nantes Angers Le Mans, CHU Angers, Angers; Christian Recher, CHU de Toulouse, Université de Toulouse III, Toulouse; Olivier Tournilhac, CHU Clermont Ferrand, Clermont Ferrand; Francis Witz, CHU Nancy, Nancy; Christian Berthou, Hôpital Augustin Morvan, Brest; Martine Escoffre-Barbe, Hôpital Pontchaillou, Rennes; Denis Guyotat, Institut de Cancérologie de la Loire, Saint Etienne; Nathalie Fegueux, Hôpital Lapeyronie, Montpellier; Chantal Himberlin, CHU Reims, Reims; Martine Delain, Hôpital Bretonneau, Tours; Bruno Lioure, CHU Hautepierre, Strasbourg; Eric Jourdan, Hôpital Caremeau, Nîmes; Frederic Bauduer, Centre Hospitalier Cote Basque, Bayonne; Francois Dreyfus, Hôpital Cochin, Paris; and Jean-Yves Cahn and Jean-Jacques Sotto, Hôpital Michallon, Grenoble, France.

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http://dx.doi.org/10.1200/JCO.2016.67.6213DOI Listing
February 2017

Therapy-related acute myeloid leukemia following treatment of lymphoid malignancies.

Oncotarget 2016 Dec;7(52):85937-85947

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.18632/oncotarget.13262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349887PMC
December 2016

Prognostic impact of viral reactivations in acute myeloid leukemia patients undergoing allogeneic stem cell transplantation in first complete response.

Medicine (Baltimore) 2016 Nov;95(48):e5356

aService d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole bUniversité Toulouse III Paul Sabatier cService d'Epidémiologie, Centre Hospitalier Universitaire de Toulouse dUMR 1027, INSERM-Université de Toulouse III eService d'Immunologie, Centre Hospitalier de Toulouse Rangueil fService de Virologie, Centre Hospitalier de Toulouse Purpan gUMR 1037, Centre de Recherche en Cancérologie de Toulouse, INSERM-Université de Toulouse III, Toulouse, France.

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http://dx.doi.org/10.1097/MD.0000000000005356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134805PMC
November 2016

CHK1 as a therapeutic target to bypass chemoresistance in AML.

Sci Signal 2016 09 13;9(445):ra90. Epub 2016 Sep 13.

Equipe Labellisée, La Ligue Contre Le Cancer, Toulouse, France. Laboratoire d'Excellence Toulouse Cancer Labex TOUCAN, Cancer Research Center of Toulouse, Inserm U1037, CNRS ERL5294, Toulouse, France. Université Paul Sabatier, Toulouse, France.

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http://dx.doi.org/10.1126/scisignal.aac9704DOI Listing
September 2016

Chemotherapy-Related Reticulate Hyperpigmentation: A Case Series and Review of the Literature.

Dermatology 2015 1;231(4):312-8. Epub 2015 Oct 1.

Department of Dermatology, Institut Claudius Regaud, Institut Universitaire du Cancer, Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1159/000439047DOI Listing
August 2016

Use of rifampin for treatment of disseminated tuberculosis in a patient with primary myelofibrosis on ruxolitinib.

Ann Hematol 2016 Jun 26;95(7):1207-9. Epub 2016 Apr 26.

Department of Infectious and Tropical Diseases, Toulouse University Hospital, Toulouse, France.

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http://link.springer.com/10.1007/s00277-016-2684-0
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http://dx.doi.org/10.1007/s00277-016-2684-0DOI Listing
June 2016

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study.

Lancet Haematol 2016 Apr 18;3(4):e186-95. Epub 2016 Mar 18.

Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, Paris, France; EA-3518, Institut Universitaire d'Hématologie, Université Paris Diderot, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(15)00247-1DOI Listing
April 2016

A Systemic Capillary Leak Syndrome (Clarkson Syndrome) in a Patient with Chronic Lymphocytic Leukemia: A Case Report in an Out-of-Hospital Setting.

Case Rep Emerg Med 2016 16;2016:5347039. Epub 2016 Mar 16.

Service d'Aide Médicale Urgente de la Haute Garonne (SAMU 31), Hôpital Universitaire de Purpan, place du Docteur Baylac, TSA 40031, 31059 Toulouse Cedex 9, France.

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http://dx.doi.org/10.1155/2016/5347039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812218PMC
April 2016

Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells.

Blood 2016 Feb 18;127(7):882-92. Epub 2015 Aug 18.

Cancer Research Center of Toulouse, Unité Mixte de Recherche (UMR)1037 INSERM, ERL5294 Centre National de la Recherche Scientifique (CNRS), Toulouse, France; Université Toulouse III Paul Sabatier, Toulouse, France; Université Paris Descartes, Faculté de Médecine Sorbonne Paris Cité, Paris, France.

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http://www.bloodjournal.org/content/bloodjournal/early/2015/
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http://www.bloodjournal.org/content/bloodjournal/127/7/882.f
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2015-05-64
Publisher Site
http://dx.doi.org/10.1182/blood-2015-05-646497DOI Listing
February 2016

Impact of obesity in favorable-risk AML patients receiving intensive chemotherapy.

Am J Hematol 2016 Feb 26;91(2):193-8. Epub 2015 Nov 26.

Service d'hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1002/ajh.24228DOI Listing
February 2016

Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations.

Mol Cancer Ther 2015 Oct 23;14(10):2364-73. Epub 2015 Jul 23.

Cancer Research Center of Toulouse (CRCT), UMR1037 INSERM, ERL5294 CNRS, Toulouse, France. Université Toulouse III Paul Sabatier, Toulouse, France. Service d'Hématologie, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0163DOI Listing
October 2015

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.

Blood 2015 Sep 17;126(11):1346-56. Epub 2015 Jul 17.

Institut Cochin, Département Développement Reproduction Cancer, Centre National de la Recherche Scientifique, Unité Mixtes de Recherche 8104, INSERM U1016, Paris, France; Ligue National Contre le Cancer, Equipe Labellisée, Paris, France; Service d'Hématologie, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France; Université Paris Descartes, Faculté de Médecine Sorbonne Paris Cité, Paris, France;

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http://dx.doi.org/10.1182/blood-2015-01-621870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608389PMC
September 2015

Hyperferritinemia at diagnosis predicts relapse and overall survival in younger AML patients with intermediate-risk cytogenetics.

Leuk Res 2015 Aug 14;39(8):818-21. Epub 2015 May 14.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France; Université Toulouse III Paul Sabatier, Toulouse, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01452126150013
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http://dx.doi.org/10.1016/j.leukres.2015.05.001DOI Listing
August 2015

INPP4B, a new player in the chemoresistance of AML.

Authors:
Christian Recher

Blood 2015 Apr;125(18):2738-9

INSTITUT UNIVERSITAIRE DU CANCER DE TOULOUSE ONCOPOLE.

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http://dx.doi.org/10.1182/blood-2015-03-633669DOI Listing
April 2015

Comparison of 60 or 90 mg/m(2) of daunorubicin in induction therapy for acute myeloid leukemia with intermediate or unfavorable cytogenetics.

Am J Hematol 2015 Feb 19;90(2):E29-30. Epub 2014 Nov 19.

Hematology Department, Institut Paoli Calmettes, Marseille, France; Aix-Marseille University, Medecine Faculty, Marseille, France.

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http://dx.doi.org/10.1002/ajh.23884DOI Listing
February 2015

Clinical activity of a new regimen combining gemcitabine and alemtuzumab in high-risk relapsed/refractory chronic lymphocytic leukemia patients.

Eur J Haematol 2015 Jan 17;94(1):37-42. Epub 2014 Sep 17.

Department of Hematology, Purpan University Hospital, Toulouse cedex, France.

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http://dx.doi.org/10.1111/ejh.12391DOI Listing
January 2015

Sorafenib plus all-trans retinoic acid for AML patients with FLT3-ITD and NPM1 mutations.

Eur J Haematol 2014 Dec 18;93(6):533-6. Epub 2014 Apr 18.

Service d'Hématologie, Centre Hospitalier Universitaire de Toulouse, Hôpital Purpan, Toulouse, France.

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http://dx.doi.org/10.1111/ejh.12334DOI Listing
December 2014

Intensive chemotherapy, azacitidine, or supportive care in older acute myeloid leukemia patients: an analysis from a regional healthcare network.

Am J Hematol 2014 Dec 20;89(12):E244-52. Epub 2014 Oct 20.

Département d'Hématologie-Médecine Interne, Centre Hospitalier Universitaire de Toulouse, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France; Service d'Hématologie, Hôpitaux Universitaires de Strasbourg, F-67098, Strasbourg, France.

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http://dx.doi.org/10.1002/ajh.23848DOI Listing
December 2014

Young patients with non-germinal center B-cell-like diffuse large B-cell lymphoma benefit from intensified chemotherapy with ACVBP plus rituximab compared with CHOP plus rituximab: analysis of data from the Groupe d'Etudes des Lymphomes de l'Adulte/lymphoma study association phase III trial LNH 03-2B.

J Clin Oncol 2014 Dec 10;32(35):3996-4003. Epub 2014 Nov 10.

Thierry Jo Molina, Danielle Canioni, and Jean-Philippe Jais, Assistance Publique-Hôpitaux de Paris (AP-HP), Necker Enfants-Malades, Université Paris Descartes, EA 7324, Sorbonne Paris Cité; Josette Brière and Catherine Thieblemont, AP-HP, Saint-Louis, Université Paris Diderot, Sorbonne Paris Cité; Catherine Thieblemont, L'Institut National de la Santé et de la Recherche Médicale (INSERM) U728; Bettina Fabiani, AP-HP, Saint-Antoine, Paris; Christiane Copie-Bergman, Corinne Haioun, Karen Leroy, and Philippe Gaulard, AP-HP, Groupe Hospitalier Henri-Mondor/Albert-Chenevier, Université Paris-Est Créteil; Christiane Copie-Bergman, Karen Leroy, and Philippe Gaulard, INSERM Unité U955 Équipe 9, Créteil; Christian Recher, Centre Hospitalier Universitaire (CHU) Purpan, Université Toulouse III Paul Sabatier, Toulouse; Françoise Berger, Gilles Salles, and Bertrand Coiffier, Hospices Civils de Lyon, Université Claude Bernard, Pierre-Bénite; Christophe Fermé, Institut Gustave Roussy, Villejuif; Marie-Christine Copin and Franck Morschauser, CHU Lille, Lille; Olivier Casasnovas and Tony Petrella, CHU Dijon, Dijon; Nicolas Mounier, CHU Nice, Nice; and Fabrice Jardin and Hervé Tilly, Centre Henri Becquerel, Université de Rouen, Rouen, France.

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http://dx.doi.org/10.1200/JCO.2013.54.9493DOI Listing
December 2014

Targeting CHK1 inhibits cell proliferation in FLT3-ITD positive acute myeloid leukemia.

Leuk Res 2014 Nov 16;38(11):1342-9. Epub 2014 Sep 16.

Cancer Research Center of Toulouse, Inserm Unité Mixte de Recherche 1037, CNRS Equipe de Recherche labellisée 5294, Université de Toulouse, Centre Hospitalier Universitaire Purpan, Toulouse, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01452126140026
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http://dx.doi.org/10.1016/j.leukres.2014.08.020DOI Listing
November 2014

The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.

Cell Rep 2014 Jun 5;7(6):1815-23. Epub 2014 Jun 5.

Equipe Labellisée Ligue contre le Cancer, Institut de Génétique Moléculaire de Montpellier, UMR 5535 CNRS, Université Montpellier 1, Université Montpellier 2, 1919 Route de Mende, 34293 Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.05.016DOI Listing
June 2014

Initial absolute lymphocyte count as a prognostic factor for outcome in acute myeloid leukemia.

Leuk Lymphoma 2014 Apr 5;55(4):855-62. Epub 2013 Aug 5.

Hematology Department, Lyon-Sud Hospital, Hospices Civils de Lyon , Pierre Bénite , France.

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http://dx.doi.org/10.3109/10428194.2013.813504DOI Listing
April 2014

Blastic island in acute myeloid leukemia.

Blood 2014 Mar;123(13):1986

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http://dx.doi.org/10.1182/blood-2013-12-544130DOI Listing
March 2014

Class I phosphoinositide 3-kinases in normal and pathologic hematopoietic cells.

Curr Top Microbiol Immunol 2012 ;362:163-84

Cancer Research Center of Toulouse and Laboratoire d'Hématologie, Hôpital de Toulouse, France.

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http://dx.doi.org/10.1007/978-94-007-5025-8_8DOI Listing
April 2013

Incidence of 17p deletions and TP53 mutation in myelodysplastic syndrome and acute myeloid leukemia with 5q deletion.

Genes Chromosomes Cancer 2012 Dec 30;51(12):1086-92. Epub 2012 Aug 30.

Laboratoire d'Hématologie, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris (AP-HP)/Université Paris 13, Bobigny. France.

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http://dx.doi.org/10.1002/gcc.21993DOI Listing
December 2012