Christian R Andres

Christian R Andres

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Christian R Andres

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Ferritin and LDL-cholesterol as biomarkers of fat-free mass loss in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Aug 3;20(5-6):441-444. Epub 2019 Apr 3.

c Laboratory of Biochemistry and Molecular Biology , University Hospital of Tours , Tours , France.

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https://www.tandfonline.com/doi/full/10.1080/21678421.2019.1
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http://dx.doi.org/10.1080/21678421.2019.1597126DOI Listing
August 2019

Plasma creatinine and amyotrophic lateral sclerosis prognosis: a systematic review and meta-analysis.

Amyotroph Lateral Scler Frontotemporal Degener 2019 May 9;20(3-4):199-206. Epub 2019 Apr 9.

a UMR 1253, Team 2, INSERM/University of Tours , Tours , France and.

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http://dx.doi.org/10.1080/21678421.2019.1572192DOI Listing
May 2019

LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b.

Biochem J 2018 12 6;475(23):3745-3761. Epub 2018 Dec 6.

Centre de Biophysique Moléculaire, CNRS, UPR 4301, University of Orléans and INSERM, 45071 Orléans Cedex 2, France.

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http://biochemj.org/lookup/doi/10.1042/BCJ20170961
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http://dx.doi.org/10.1042/BCJ20170961DOI Listing
December 2018

The Metabolic Disturbances of Motoneurons Exposed to Glutamate.

Mol Neurobiol 2018 Oct 12;55(10):7669-7676. Epub 2018 Feb 12.

INSERM U930 "Imagerie et Cerveau," CHRU de Tours, Université François-Rabelais, Tours, France.

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http://dx.doi.org/10.1007/s12035-018-0945-8DOI Listing
October 2018

Phenotypic and genotypic studies of ALS cases in ALS-SMA families.

Amyotroph Lateral Scler Frontotemporal Degener 2018 08 1;19(5-6):432-437. Epub 2018 Mar 1.

k Clinique du Motoneurone, Explorations neurologiques, CHU Gui de Chauliac , Université de Montpellier , Montpellier , France.

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http://dx.doi.org/10.1080/21678421.2018.1440406DOI Listing
August 2018

Identification of metabolic pathway disturbances using multimodal metabolomics in autistic disorders in a Middle Eastern population.

J Pharm Biomed Anal 2018 Apr 3;152:57-65. Epub 2018 Feb 3.

Université François-Rabelais, INSERM U930, Equipe neurogénétique et neurométabolomique, France; Laboratoire de Biochimie et Biologie moléculaire, CHRU de Tours, France. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.01.007DOI Listing
April 2018

How Can a Ketogenic Diet Improve Motor Function?

Front Mol Neurosci 2018 26;11:15. Epub 2018 Jan 26.

INSERM 1083, CNRS, Equipe Mitolab, Institut MITOVASC, UMR 6015, Université d'Angers, Angers, France.

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http://dx.doi.org/10.3389/fnmol.2018.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790787PMC
January 2018

Workflow methodology for rat brain metabolome exploration using NMR, LC-MS and GC-MS analytical platforms.

J Pharm Biomed Anal 2017 Aug 13;142:270-278. Epub 2017 May 13.

Université François-Rabelais, INSERM U930 "Imagerie et Cerveau", CHRU de Tours, 10 Bv Tonnellé, 37044 Tours, France. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2017.03.068DOI Listing
August 2017

An UPLC-MSMS method to measure plasma homocysteine concentration.

Ann Biol Clin (Paris) 2017 Jun;75(3):334-338

Laboratoire de biochimie et biologie moléculaire, CHRU Tours, France, Inserm U930, Université François Rabelais, Tours, France.

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http://dx.doi.org/10.1684/abc.2017.1248DOI Listing
June 2017

Ursodeoxycholic acid therapy in intrahepatic cholestasis of pregnancy: Results in real-world conditions and factors predictive of response to treatment.

Dig Liver Dis 2017 Jan 20;49(1):63-69. Epub 2016 Oct 20.

Department of Hepatology and Gastroenterology, University Hospital of Tours, Tours, France.

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http://dx.doi.org/10.1016/j.dld.2016.10.006DOI Listing
January 2017

Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis.

Mol Neurobiol 2016 12 14;53(10):6910-6924. Epub 2015 Dec 14.

UMR INSERM U930, Université François-Rabelais de Tours, Equipe « Neurogénétique et neurométabolomique », 37032, Tours, France.

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http://dx.doi.org/10.1007/s12035-015-9567-6DOI Listing
December 2016

Low specificity of urinary 3-methoxytyramine in screening of dopamine-secreting pheochromocytomas and paragangliomas.

Clin Biochem 2016 Oct 18;49(15):1205-1208. Epub 2016 May 18.

Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital Bretonneau, CHRU de Tours, 2, Bd Tonnellé, 37044 Tours Cedex 1, France; Unité INSERM U930, équipe "neurogénétique et neurométabolomique", Université François Rabelais, 10 BD Tonnellé, BP 3223, 37032 Tours Cedex 1, France.

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http://dx.doi.org/10.1016/j.clinbiochem.2016.05.008DOI Listing
October 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Specific Metabolome Profile of Exhaled Breath Condensate in Patients with Shock and Respiratory Failure: A Pilot Study.

Metabolites 2016 Sep 1;6(3). Epub 2016 Sep 1.

Department of Anesthesiology and Intensive Care, CHRU Tours Bretonneau, 2 boulevard Tonnellé, 37044 Tours cedex 9, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041125PMC
http://dx.doi.org/10.3390/metabo6030026DOI Listing
September 2016

NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity.

Front Cell Neurosci 2016 9;10:118. Epub 2016 May 9.

Institut National de la Santé et de la Recherche Médicale (INSERM U930) "Imagerie et Cerveau", CHRU de Tours, Université François-RabelaisTours, France; Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital Bretonneau, CHRU de ToursTours, France.

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http://dx.doi.org/10.3389/fncel.2016.00118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860417PMC
May 2016

Mutation screening of the ubiquitin ligase gene RNF135 in French patients with autism.

Psychiatr Genet 2015 Dec;25(6):263-7

aUMR INSERM U930, University François-Rabelais bCHRU Tours, Department of Pedopsychiatry cCHRU Tours, Department of Biochemistry and Molecular Biology dCNRS UPR 4301, CBM, Orléans.

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http://dx.doi.org/10.1097/YPG.0000000000000100DOI Listing
December 2015

Analytical methodology for metabolomics study of adherent mammalian cells using NMR, GC-MS and LC-HRMS.

Anal Bioanal Chem 2015 Nov 7;407(29):8861-72. Epub 2015 Oct 7.

INSERM U930 "Imagerie et Cerveau", CHRU de Tours, Université François-Rabelais, 10 Bv Tonnellé, 37044, Tours, France.

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http://dx.doi.org/10.1007/s00216-015-9047-xDOI Listing
November 2015

Vitamin D is Not a Protective Factor in ALS.

CNS Neurosci Ther 2015 Aug 20;21(8):651-6. Epub 2015 Jun 20.

Unité mixte de recherche U930, Institut National de la Santé et de la Recherche Médicale, Université François-Rabelais, Tours, France.

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http://dx.doi.org/10.1111/cns.12423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495158PMC
August 2015

Iron metabolism disturbance in a French cohort of ALS patients.

Biomed Res Int 2014 2;2014:485723. Epub 2014 Jul 2.

Unité Mixte de Recherche U930, Institut National de la Santé et de la Recherche Médicale, Université François-Rabelais, Equipe "Neurogénétique et Neurométabolomique", 10 boulevard Tonnellé, 37032 Tours, France ; Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours, 37044 Tours, France.

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http://dx.doi.org/10.1155/2014/485723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101961PMC
April 2015

Management of the cutaneous reaction induced by scorpion sting: thinking about treatment and means of prevention.

Presse Med 2015 Apr 9;44(4 Pt 1):466-8. Epub 2015 Feb 9.

CHU de Tours, hôpital Bretonneau, service de parasitologie, mycologie, médecine tropicale, 37044 Tours cedex 9, France; Université François-Rabelais, CEPR, Inserm U1100/E.A. 6305, Faculté de médecine, 37032 Tours cedex, France.

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http://dx.doi.org/10.1016/j.lpm.2014.10.013DOI Listing
April 2015

The BDNF Val(66)Met polymorphism is associated with escitalopram response in depressed patients.

Psychopharmacology (Berl) 2015 Feb 31;232(3):575-81. Epub 2014 Jul 31.

Clinique Psychiatrique Universitaire, Centre Expert Dépression Résistante, Fondation FondaMental, CHRU de Tours, 37044, Tours Cedex 9, France,

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http://dx.doi.org/10.1007/s00213-014-3694-zDOI Listing
February 2015

[Investigation of hyperhomocysteinemia].

Ann Biol Clin (Paris) 2013 Sep-Oct;71(5):517-25

Laboratoire de biochimie et biologie moléculaire, CHRU de Tours, Tours, France, Inserm U930, Equipe neurogénétique et neurométabolomique, Université François Rabelais, Tours, France.

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http://dx.doi.org/10.1684/abc.2013.0879DOI Listing
July 2014

Combined 1H-NMR and 1H-13C HSQC-NMR to improve urinary screening in autism spectrum disorders.

Analyst 2014 Jul;139(13):3460-8

Equipe neurogénétique et neurométabolomique INSERM U930, Université François Rabelais, PPF "Analyses des Systèmes Biologiques", UFR de Médecine, 10 BlvdTonnellé, 37044 Tours Cedex 9, 37000 Tours, France.

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http://dx.doi.org/10.1039/c4an00552jDOI Listing
July 2014

Untargeted 1H-NMR metabolomics in CSF: toward a diagnostic biomarker for motor neuron disease.

Neurology 2014 Apr 28;82(13):1167-74. Epub 2014 Feb 28.

From UMR Inserm U930 (H.B., L.N.-D., C.A., C.V.-D., S.M., P.E., C.R.A., P.C.), Tours; Université François-Rabelais (H.B., L.N.-D., C.A., C.V.-D., S.M., P.E., C.R.A., P.C.), Tours; Laboratoire de Biochimie et Biologie Moléculaire (H.B., C.A., P.E., C.R.A.), CHRU de Tours; PPF-ASB (L.N.-D., P.E.), Université François-Rabelais, Tours; Fédération des Maladies du Système Nerveux (P.-F.P., P.H.G.), Centre Référent Maladie Rare SLA, Hôpital de la Pitié-Salpétrière, Paris; Service de Neurologie (C.M., D.D.), CHRU de Lille; and Centre SLA (P.C.), Service de Neurologie, CHRU Bretonneau, Tours, France.

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http://dx.doi.org/10.1212/WNL.0000000000000274DOI Listing
April 2014

Association of a paraneoplastic motor neuron disease with anti-Ri antibodies and a novel SOD1 I18del mutation.

J Neurol Sci 2014 Feb 27;337(1-2):212-4. Epub 2013 Nov 27.

Service de Neurologie et Neurophysiologie Clinique, CHRU Tours, France.

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http://dx.doi.org/10.1016/j.jns.2013.11.025DOI Listing
February 2014

Novel SOD1 mutation p.V31A identified with a slowly progressive form of amyotrophic lateral sclerosis.

Neurobiol Aging 2014 Jan 15;35(1):266.e1-4. Epub 2013 Aug 15.

UMR INSERM U930, Université François-Rabelais, Tours, PRES Centre - Val de Loire Université, France.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.07.012DOI Listing
January 2014

A deletion causing NF2 exon 9 skipping is associated with familial autosomal dominant intramedullary ependymoma.

Neuro Oncol 2014 Jan 18;16(2):250-5. Epub 2013 Dec 18.

Corresponding author: Ilyess Zemmoura, MD, Service de Neurochirurgie, CHRU Bretonneau, 2 boulevard Tonnellé, 37004, Tours Cedex, France.

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http://dx.doi.org/10.1093/neuonc/not165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895380PMC
January 2014

Total protein level in cerebrospinal fluid is stable in elderly adults.

J Am Geriatr Soc 2013 Oct;61(10):1819-21

Nuclear Medicine Laboratory, Centre Hospitalier Régional Universitaire, Tours, France; Université François-Rabelais de Tours, PRES Centre-Val de Loire Université, Tours, France; UMR INSERM U 930 Imagerie et cerveau, Université François-Rabelais de Tours, PRES Centre-Val de Loire Université, Tours, France.

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http://dx.doi.org/10.1111/jgs.12489DOI Listing
October 2013

Benign lower limb amyotrophy due to TARDBP mutation or post-polio syndrome?

Amyotroph Lateral Scler Frontotemporal Degener 2013 Sep 28;14(5-6):476-8. Epub 2013 Jan 28.

Centre SLA, CHU Bretonneau, 2 Boulevard Tonnellé, Tours Cedex 1, France.

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http://dx.doi.org/10.3109/21678421.2013.764567DOI Listing
September 2013

1H-13C NMR-based urine metabolic profiling in autism spectrum disorders.

Talanta 2013 Sep 9;114:95-102. Epub 2013 Apr 9.

Université François-Rabelais, INSERM U930, Equipe neurogénétique et neurométabolomique, CHRU de Tours, 10 Bv Tonnellé, 37044 Tours, France.

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http://dx.doi.org/10.1016/j.talanta.2013.03.064DOI Listing
September 2013

Protein SUMOylation, an emerging pathway in amyotrophic lateral sclerosis.

Int J Neurosci 2013 Jun 4;123(6):366-74. Epub 2013 Feb 4.

UMR INSERM U930, Université François-Rabelais, Tours, France.

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http://dx.doi.org/10.3109/00207454.2012.761984DOI Listing
June 2013

GC-MS-based urine metabolic profiling of autism spectrum disorders.

Anal Bioanal Chem 2013 Jun 10;405(15):5291-300. Epub 2013 Apr 10.

INSERM U930, Equipe neurogénétique et neurométabolomique, CHRU de Tours, Hôpital Bretonneau, Université François-Rabelais, 10 Bv Tonnellé, 37044 Tours, France.

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http://dx.doi.org/10.1007/s00216-013-6934-xDOI Listing
June 2013

Renal impairment and ischemic stroke risk assessment in patients with atrial fibrillation: the Loire Valley Atrial Fibrillation Project.

J Am Coll Cardiol 2013 May 21;61(20):2079-87. Epub 2013 Mar 21.

University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097130111
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http://dx.doi.org/10.1016/j.jacc.2013.02.035DOI Listing
May 2013

Is NMR metabolic profiling of spent embryo culture media useful to assist in vitro human embryo selection?

MAGMA 2013 Apr 10;26(2):193-202. Epub 2012 Aug 10.

INSERM U930, UFR de Médecine, 10 Blvd Tonnellé, 37044, Tours Cedex 9, France.

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http://dx.doi.org/10.1007/s10334-012-0331-xDOI Listing
April 2013

Amyotrophic lateral sclerosis: a hormonal condition?

Amyotroph Lateral Scler 2012 Oct 8;13(6):585-8. Epub 2012 Aug 8.

UMR INSERM U930, Université François Rabelais de Tours, Tours, France.

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http://dx.doi.org/10.3109/17482968.2012.706303DOI Listing
October 2012

Study of the HFE gene common polymorphisms in French patients with sporadic amyotrophic lateral sclerosis.

J Neurol Sci 2012 Jun 14;317(1-2):58-61. Epub 2012 Mar 14.

UMR INSERM U930, Université François-Rabelais, Tours, France; Centre SLA, Service de Neurologie et Neurophysiologie Clinique, CHRU de Tours, France.

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http://dx.doi.org/10.1016/j.jns.2012.02.029DOI Listing
June 2012

LIMK2d, a truncated isoform of Lim kinase 2 regulates neurite growth in absence of the LIM kinase domain.

Biochem Biophys Res Commun 2012 Apr 3;420(2):247-52. Epub 2012 Mar 3.

UMR INSERM U930, CNRS ERL 3106, Université François Rabelais, Tours, France.

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http://dx.doi.org/10.1016/j.bbrc.2012.02.134DOI Listing
April 2012

Fetal exposure to teratogens: evidence of genes involved in autism.

Neurosci Biobehav Rev 2011 Apr 30;35(5):1254-65. Epub 2010 Dec 30.

UMR INSERM U930, CNRS ERL 3106, Université François Rabelais de Tours, Tours, France.

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http://dx.doi.org/10.1016/j.neubiorev.2010.12.013DOI Listing
April 2011

CADASIL and ALS: a link?

Amyotroph Lateral Scler 2010 Aug;11(4):399-401

ALS Centre, Service de Neurologie et de Neurophysiologie Clinique, CHRU, Tours, France.

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http://dx.doi.org/10.1080/17482960903033153DOI Listing
August 2010

Association study of the ubiquitin conjugating enzyme gene UBE2H in sporadic ALS.

Amyotroph Lateral Scler 2009 Oct-Dec;10(5-6):432-5

INSERM U930, Université François Rabelais Tours, Montpellier, France.

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http://dx.doi.org/10.3109/17482960802444972DOI Listing
February 2010

Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress.

Behav Brain Res 2009 Sep 5;202(2):245-51. Epub 2009 Apr 5.

U930, INSERM, Tours, France; Université François Rabelais de Tours, Tours, France.

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http://dx.doi.org/10.1016/j.bbr.2009.03.040DOI Listing
September 2009

What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor?

J Mol Evol 2009 Jun 19;68(6):616-28. Epub 2009 May 19.

Faculté de Médecine, Génétique de l'Autisme et des Déficiences Mentales, INSERM U930, Université François Rabelais, 10, boulevard Tonnellé, BP 3223, 37032, Tours, France.

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http://dx.doi.org/10.1007/s00239-009-9225-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691932PMC
June 2009

Mutations of the ANG gene in French patients with sporadic amyotrophic lateral sclerosis.

Arch Neurol 2008 Oct;65(10):1333-6

INSERM U930, Université François Rabelais Tours, CHRU de Tours, Faculté de Médecine, 10 boulevard Tonnellé, BP3223, 37032 Tours CEDEX, France.

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http://dx.doi.org/10.1001/archneur.65.10.1333DOI Listing
October 2008

Transmission disequilibrium study of an oligodendrocyte and myelin glycoprotein gene allele in 431 families with an autistic proband.

Neurosci Res 2007 Dec 19;59(4):426-30. Epub 2007 Aug 19.

INSERM, U619, Université François-Rabelais de Tours, CHRU de Tours, Faculté de Médecine, 10 Boulevard Tonnellé, BP3223, 37032, Tours Cedex, France.

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http://dx.doi.org/10.1016/j.neures.2007.08.009DOI Listing
December 2007