Publications by authors named "Christian R A Regenbrecht"

15 Publications

  • Page 1 of 1

Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model.

Authors:
Theresa M Thole Joern Toedling Annika Sprüssel Sebastian Pfeil Larissa Savelyeva David Capper Clemens Messerschmidt Dieter Beule Stefanie Groeneveld-Krentz Cornelia Eckert Guido Gambara Anton G Henssen Sabine Finkler Johannes H Schulte Anja Sieber Nils Bluethgen Christian R A Regenbrecht Annette Künkele Marco Lodrini Angelika Eggert Hedwig E Deubzer

Int J Cancer 2020 02 1;146(4):1031-1041. Epub 2019 Aug 1.

Department of Pediatric Hematology and Oncology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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February 2020

Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.

Authors:
Dirk Schumacher Geoffroy Andrieux Karsten Boehnke Marlen Keil Alessandra Silvestri Maxine Silvestrov Ulrich Keilholz Johannes Haybaeck Gerrit Erdmann Christoph Sachse Markus Templin Jens Hoffmann Melanie Boerries Reinhold Schäfer Christian R A Regenbrecht

PLoS Genet 2019 03 29;15(3):e1008076. Epub 2019 Mar 29.

cpo-Cellular Phenomics & Oncology Berlin-Buch GmbH, Berlin, Germany.

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March 2019

From Chemotherapy to Combined Targeted Therapeutics: and Models to Decipher Intra-tumor Heterogeneity.

Authors:
Guido Gambara Manuela Gaebler Ulrich Keilholz Christian R A Regenbrecht Alessandra Silvestri

Front Pharmacol 2018 14;9:77. Epub 2018 Feb 14.

cpo - Cellular Phenomics & Oncology Berlin-Buch GmbH, Berlin, Germany.

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February 2018

Non-Canonical Hedgehog Signaling Is a Positive Regulator of the WNT Pathway and Is Required for the Survival of Colon Cancer Stem Cells.

Authors:
Joseph L Regan Dirk Schumacher Stephanie Staudte Andreas Steffen Johannes Haybaeck Ulrich Keilholz Caroline Schweiger Nicole Golob-Schwarzl Dominik Mumberg David Henderson Hans Lehrach Christian R A Regenbrecht Reinhold Schäfer Martin Lange

Cell Rep 2017 Dec;21(10):2813-2828

Bayer AG, Drug Discovery, Pharmaceuticals, 13342 Berlin, Germany. Electronic address:

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December 2017

Three-Dimensional Patient-Derived Sarcoma Models: Promising Tools for Improving Clinical Tumor Management.

Authors:
Manuela Gaebler Alessandra Silvestri Johannes Haybaeck Peter Reichardt Caitlin D Lowery Louis F Stancato Gabriele Zybarth Christian R A Regenbrecht

Front Oncol 2017 11;7:203. Epub 2017 Sep 11.

cpo - Cellular Phenomics & Oncology Berlin-Buch GmbH, Berlin, Germany.

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September 2017

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

Authors:
Moritz Schütte Thomas Risch Nilofar Abdavi-Azar Karsten Boehnke Dirk Schumacher Marlen Keil Reha Yildiriman Christine Jandrasits Tatiana Borodina Vyacheslav Amstislavskiy Catherine L Worth Caroline Schweiger Sandra Liebs Martin Lange Hans-Jörg Warnatz Lee M Butcher James E Barrett Marc Sultan Christoph Wierling Nicole Golob-Schwarzl Sigurd Lax Stefan Uranitsch Michael Becker Yvonne Welte Joseph Lewis Regan Maxine Silvestrov Inge Kehler Alberto Fusi Thomas Kessler Ralf Herwig Ulf Landegren Dirk Wienke Mats Nilsson Juan A Velasco Pilar Garin-Chesa Christoph Reinhard Stephan Beck Reinhold Schäfer Christian R A Regenbrecht David Henderson Bodo Lange Johannes Haybaeck Ulrich Keilholz Jens Hoffmann Hans Lehrach Marie-Laure Yaspo

Nat Commun 2017 02 10;8:14262. Epub 2017 Feb 10.

Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics/Otto Warburg Laboratory Gene Regulation and Systems Biology of cancer, Ihnestrasse 73, D-14195 Berlin, Germany.

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February 2017

Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures.

Authors:
Karsten Boehnke Philip W Iversen Dirk Schumacher María José Lallena Rubén Haro Joaquín Amat Johannes Haybaeck Sandra Liebs Martin Lange Reinhold Schäfer Christian R A Regenbrecht Christoph Reinhard Juan A Velasco

J Biomol Screen 2016 Oct 27;21(9):931-41. Epub 2016 May 27.

Eli Lilly and Company, Lilly Research Laboratories, Quantitative Biology, Alcobendas, Madrid, Spain

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October 2016

Status of estrogen receptor 1 (ESR1) gene in mastopathy predicts subsequent development of breast cancer.

Authors:
Savas D Soysal Incken B Kilic Christian R A Regenbrecht Sandra Schneider Simone Muenst Nerbil Kilic Uwe Güth Manfred Dietel Luigi M Terracciano Ergin Kilic

Breast Cancer Res Treat 2015 Jun 16;151(3):709-15. Epub 2015 May 16.

Department of Surgery, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland,

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June 2015

The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells.

Authors:
Torben Redmer Yvonne Welte Diana Behrens Iduna Fichtner Dorothea Przybilla Wasco Wruck Marie-Laure Yaspo Hans Lehrach Reinhold Schäfer Christian R A Regenbrecht

PLoS One 2014 5;9(5):e92596. Epub 2014 May 5.

Institute of Pathology - University Hospital Berlin, Berlin, Germany; Laboratory of Functional Genomics (LFGC) - University Hospital Berlin, Berlin, Germany; Comprehensive Cancer Center Charité - University Hospital Berlin, Berlin, Germany.

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June 2015

Increased activity of mitogen activated protein kinase pathway in flotillin-2 knockout mouse model.

Authors:
Antje Banning Christian R A Regenbrecht Ritva Tikkanen

Cell Signal 2014 Feb 9;26(2):198-207. Epub 2013 Nov 9.

Institute of Biochemistry, Medical Faculty, University of Giessen, Friedrichstrasse 24, 35392 Giessen, Germany. Electronic address:

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February 2014

Patient derived cell culture and isolation of CD133⁺ putative cancer stem cells from melanoma.

Authors:
Yvonne Welte Cathrin Davies Reinhold Schäfer Christian R A Regenbrecht

J Vis Exp 2013 Mar 13(73):e50200. Epub 2013 Mar 13.

Institute of Pathology, Laboratory of Molecular Tumor Pathology, Charité - Universitätsmedizin Berlin.

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March 2013

Characterization of small spheres derived from various solid tumor cell lines: are they suitable targets for T cells?

Authors:
Antonia Busse Anne Letsch Alberto Fusi Anika Nonnenmacher David Stather Sebastian Ochsenreither Christian R A Regenbrecht Ulrich Keilholz

Clin Exp Metastasis 2013 Aug 22;30(6):781-91. Epub 2013 Mar 22.

Department of Medicine III, Charité, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany,

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August 2013

Data management strategies for multinational large-scale systems biology projects.

Authors:
Wasco Wruck Martin Peuker Christian R A Regenbrecht

Brief Bioinform 2014 Jan 9;15(1):65-78. Epub 2012 Oct 9.

Institute of Pathology, Charite - Universitaetsmedizin Berlin, Chariteplatz 1, 10117 Berlin. Tel.: +49 30 2093 8951; Fax: +49 30 450 536 909;

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January 2014

Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases.

Authors:
Pedro Duenisch Rupert Reichart Ulrike Mueller Michael Brodhun Rolf Bjerkvig Bernd Romeike Jan Walter Christian Herbold Christian R A Regenbrecht Rolf Kalff Susanne A Kuhn

J Cancer Res Clin Oncol 2011 Mar 4;137(3):399-414. Epub 2010 May 4.

Department of Neurosurgery, Medical Center, Friedrich-Schiller-University, Erlanger Allee 101, 07747, Jena, Germany.

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March 2011

Glioblastoma cells express functional cell membrane receptors activated by daily used medical drugs.

Authors:
Susanne A Kuhn Ulrike Mueller Uwe-K Hanisch Christian R A Regenbrecht Ilona Schoenwald Michael Brodhun Hartwig Kosmehl Christian Ewald Rolf Kalff Rupert Reichart

J Cancer Res Clin Oncol 2009 Dec 19;135(12):1729-45. Epub 2009 Jun 19.

Department of Neurosurgery, Medical Center, Friedrich-Schiller-University, Erlanger Allee 101, 07747 Jena, Germany.

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December 2009