Publications by authors named "Christian Lechner"

29Publications

Treatment and outcome of aquaporin-4 antibody-positive NMOSD: A multinational pediatric study.

Neurol Neuroimmunol Neuroinflamm 2020 09 30;7(5). Epub 2020 Jul 30.

From the Department of Neurology (R.B.P., S.L.A.-P., J.A.d.P.) and Department of Radiology (INRAD) (C.d.M.R.), Hospital das Clínicas, Faculty of Medicine, University of São Paulo (HCFMUSP), Brazil; Queen Square MS Centre (Y.H., O.C.), UCL Institute of Neurology, Faculty of Brain Sciences, University College London; Department of Paediatric Neurology (Y.H., C.H.), Great Ormond Street Hospital for Children, London, United Kingdom; Assistance Publue-Hôpitaux de Paris (E.Y., K.D.), University Hospitals Paris South, Bicêtre Hospital, Le Kremlin Bicêtre, France; Neuroimmunology Program (T.A.) and Neurology Service (A.S.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, and Pediatric Neuroimmunology Unit (T.A.), Sant Joan de Deu (SJD) Children's Hospital, Universitat de Barcelona, Spain; Department of Neurology (A.B., R.N.), Erasmus University Medical Center, Rotterdam, the Netherlands; Division of Paediatric Neurology (C.L., M.B.), Department of Pediatrics I, Medical University of Innsbruck, Austria; Medical Center of Physical Therapy and Pain Medicine INNOVO (Y.M.), Lviv, Ukraine; Division of Pediatric Neurology (M.B.), Department of Pediatrics and Adolescent Medicine, and Department of Neurology (B.K.), Medical University of Vienna, Austria; Pediatric Neurology (E.W.), Birmingham Women and Children's Hospital, United Kingdom; Department of Neuroscience (L.P.), Pediatric Multiple Sclerosis Center, Bambino Gesù Children Hospital, IRCCS, Rome, Italy; Department of Neurology (M.C.) and Regional Multiple Sclerosis Centre (M.C.), University Hospital San Luigi Gonzaga, Orbassano, Italy; Department of Pediatric Neurology (K.R.), Vestische Kinder und Jugendklinik, Witten/Herdecke University, Datteln, Germany; Children's Neurosciences (M.L.), Evelina London Children's Hospital at Guy's and St Thomas' NHS Foundation Trust, King's Health Partners Academic Health Science Centre; Faculty of Life Sciences and Medicine (M.L.), King's College Hospital, London, United Kingdom; Neurology Department (R.M.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon; French Reference Network of Rare Inflammatory Brain and Spinal Diseases (R.M., K.D.), Le Kremlin Bicêtre, France; School of Medicine (D.K.S.), Brain Institute of Rio Grande do Sul (Brains), Pontifical Catholic University of Rio Grande Do Sul (PUCRS), Porto Alegre, Brazil; and Inserm UMR 1184 (K.D.), Immunology of Viral Infections and Autoimmune Diseases, CEA, IDMIT, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1212/NXI.0000000000000837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413715PMC
September 2020

Epidemiology of Pediatric NMOSD in Germany and Austria.

Front Neurol 2020 15;11:415. Epub 2020 May 15.

Department of Pediatric Neurology, Children's Hospital Datteln, University Witten/Herdecke, Datteln, Germany.

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http://dx.doi.org/10.3389/fneur.2020.00415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326092PMC
May 2020

Clinical and imaging features of children with autoimmune encephalitis and MOG antibodies.

Neurol Neuroimmunol Neuroinflamm 2020 07 1;7(4). Epub 2020 May 1.

From the Department of Radiology (A.W.-P., R.C.), Children's Hospital Datteln, University Witten/Herdecke; Department of Pediatrics (E.-M.W.), Olgahospital, Klinikum Stuttgart, Germany; Division of Pediatric Neurology (M. Baumann, C.L.), Department of Pediatrics I, Medical University of Innsbruck, Austria; Department of Pediatric Neurology (A.B., K.R.), Children's Hospital Datteln, University Witten/Herdecke; Department of Pediatrics (M.H.), Division of Neuropediatrics and Social Pediatrics, Medical University RWTH Aachen, Germany; Charité-Universitätsmedizin Berlin (E.K.), Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Germany; Department of Neuropediatrics (E.K.), Berlin, Germany; Department of Pediatrics and Adolescent Medicine (E.R.-F., M. Breu), Medical University of Vienna; St. Anna Children´s Hospital (E.R.-F.), Vienna, Austria; Klinik für Kinder und Jugendmedizin (Ö.S.), Evangelisches Krankenhaus Hamm, Germany; Department of Neuropediatrics (A.D.M.), Developmental Neurology and Social Pediatrics, Children's Hospital, University of Duisburg-Essen, Germany; Department of Pediatrics (R.P.), Christliches Kinderhospital Osnabrück, Germany; Department of Pediatric Neurology (M.P.), Children's Hospital Auf der Bult, Hannover Germany; Department of Neonatology (C.R.), Pediatric Intensive Care, Sleep Medicine, Children's Hospital Datteln, University Witten/Herdecke, Germany; Institute of Neurology (R.H.), Medical University of Vienna, Austria; Neuroimmunology (F.L.), Institute of Clinical Chemistry and Department of Neurology, Christian-Albrechts-University Kiel and Medical University Hospital Schleswig-Holstein, Germany; and Clinical Department of Neurology (M.R.), Medical University of Innsbruck, Austria.

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http://dx.doi.org/10.1212/NXI.0000000000000731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217659PMC
July 2020

Concentration Dependence of the Unbound Partition Coefficient Kp and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors.

Drug Metab Dispos 2020 07 1;48(7):553-562. Epub 2020 May 1.

Bayer AG, Pharma R&D, Translational Sciences, Research Pharmacokinetics, Berlin, Germany (C.T., C.L., A.R.); Bayer AG, Pharma R&D, Therapeutic Compound Research, Berlin, Germany (D.K.); Bayer AG, Pharma R&D, Small Molecule Innovation, Berlin, Germany (L.B., N.B., A.F.-M) and Technische Universität Berlin, Institut für Chemie, Berlin, Germany (C.T., R.D.S.)

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http://dx.doi.org/10.1124/dmd.120.090563DOI Listing
July 2020

[]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors.

Molecules 2019 Nov 13;24(22). Epub 2019 Nov 13.

Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethovenstraße 55, 38106 Braunschweig, Germany.

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http://dx.doi.org/10.3390/molecules24224090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891749PMC
November 2019

The BCR-ABL inhibitor nilotinib influences phenotype and function of monocyte-derived human dendritic cells.

Cancer Immunol Immunother 2018 May 21;67(5):775-783. Epub 2018 Feb 21.

Department of Medical Oncology, Hematology, Immunology, Rheumatology and Pulmology, University Hospital Tübingen, Otfried-Müller-Straße 10, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00262-018-2129-9DOI Listing
May 2018

Fast and calibration free determination of first order reaction kinetics in API synthesis using in-situ ATR-FTIR.

Eur J Pharm Biopharm 2018 May 28;126:95-100. Epub 2017 Sep 28.

TU Braunschweig, Institute for Chemical and Thermal Process Engineering, Langer Kamp 7, 38106 Braunschweig, Germany; TU Braunschweig, Center of Pharmaceutical Engineering, Franz-Liszt-Straße 35a, 38106 Braunschweig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2017.09.013DOI Listing
May 2018

MOG Spectrum Disorders and Role of MOG-Antibodies in Clinical Practice.

Neuropediatrics 2018 02 31;49(1):3-11. Epub 2017 Aug 31.

Department of Pediatric Neurology, Vestische Kinder- und Jugendklinik Datteln, Witten/Herdecke University, Datteln, Germany.

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http://dx.doi.org/10.1055/s-0037-1604404DOI Listing
February 2018

Impact of Experimental Conditions on the Evaluation of Interactions between Multidrug and Toxin Extrusion Proteins and Candidate Drugs.

Drug Metab Dispos 2016 08 6;44(8):1381-9. Epub 2016 Jun 6.

Pharmacokinetics and Non-Clinical Safety Department, Nippon Boehringer Ingelheim Co., Ltd., Kobe, Japan (C.L., N.I., A.F., H.S., N.O., M.T., K.N., I.W., N.Y.); and Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (H.K.)

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http://dx.doi.org/10.1124/dmd.115.068163DOI Listing
August 2016

Cellular cytokine and chemokine responses to parasite antigens and fungus and mite allergens in children co-infected with helminthes and protozoa parasites.

J Inflamm (Lond) 2015 20;12. Epub 2015 Jan 20.

Institute for Tropical Medicine, University Clinics Tübingen, Wilhelmstraße 27, 72074 Tübingen, Germany ; Institut National d'Hygiène - Onchocerciasis Reference Laboratory, Sokodé, Togo.

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http://dx.doi.org/10.1186/s12950-015-0050-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334608PMC
February 2015

A giant mesenteric desmoid tumor revealed by acute pulmonary embolism due to compression of the inferior vena cava.

Am J Case Rep 2014 Sep 2;15:374-7. Epub 2014 Sep 2.

Department of General and Digestive Surgery, Chalons en Champagne Hopsital, Chalons en Champagne, France.

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http://dx.doi.org/10.12659/AJCR.891044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159246PMC
September 2014

Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease.

Med Microbiol Immunol 2014 Jun 9;203(3):185-93. Epub 2014 Feb 9.

Institute for Tropical Medicine, University of Tübingen, Wilhelmstraße 27, 72074, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00430-014-0331-8DOI Listing
June 2014

Parasite-specific IL-17-type cytokine responses and soluble IL-17 receptor levels in Alveolar Echinococcosis patients.

Clin Dev Immunol 2012 30;2012:735342. Epub 2012 Aug 30.

Institute for Tropical Medicine, University of Tübingen Clinics, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1155/2012/735342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437316PMC
January 2013

Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles.

Eur J Pharm Biopharm 2010 Jun 20;75(2):284-90. Epub 2010 Mar 20.

Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejpb.2010.03.008DOI Listing
June 2010

Acute and chronic neuroendocrine effects of interferon-beta 1a in multiple sclerosis.

Clin Endocrinol (Oxf) 2007 Feb;66(2):295-303

Max Planck Institute of Psychiatry, Section of Neurology, Kraepelinstrasse 10, 80804 München, Germany.

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http://doi.wiley.com/10.1111/j.1365-2265.2006.02725.x
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http://dx.doi.org/10.1111/j.1365-2265.2006.02725.xDOI Listing
February 2007

Hit/Miss monitoring of ESWL by spectral Doppler ultrasound.

Ultrasound Med Biol 2003 May;29(5):705-12

Dornier MedTech, Wessling, Germany.

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http://dx.doi.org/10.1016/s0301-5629(02)00773-1DOI Listing
May 2003